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Sökning: WFRF:(Wandell P. E.)

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1.
  • Malmström, H., et al. (författare)
  • Low fructosamine and mortality - A long term follow-up of 215,011 non-diabetic subjects in the Swedish AMORIS study
  • 2016
  • Ingår i: NMCD. Nutrition Metabolism and Cardiovascular Diseases. - : Elsevier BV. - 0939-4753 .- 1590-3729. ; 26:12, s. 1120-1128
  • Tidskriftsartikel (refereegranskat)abstract
    • Background and aims: Both high and low fasting glucose has been associated with an increased mortality among individuals without diabetes. This J-shaped association has also been shown for HbA1c in relation to all-cause mortality. High fructosamine is associated with increased mortality. In this study we aim to evaluate if low fructosamine is also associated with increased mortality in non-diabetic subjects. Methods and results: We included 215,011 subjects from the AMORIS cohort undergoing occupational health screening or primary care in Stockholm, Sweden. Cause specific mortality was obtained from the Swedish Cause-of-Death Register by record linkage. Hazard ratios for the lowest decile of fructosamine were estimated by Cox regression for all-cause (n = 41,388 deaths) and cause-specific mortality during 25 years of follow-up. We observed gradually increased mortality with lower fructosamine in a large segment of the population. In the lowest decile of fructosamine the sex, age, social class and calendar adjusted hazard ratio was 1.20 (95% CI; 1.18-1.27) compared to deciles 2-9. This increased mortality was attenuated after adjustment for six other biomarkers (HR = 1.11 (95% CI; 1.07-1.15)). Haptoglobin, an indicator of chronic inflammation, made the greatest difference in the point estimate. In sensitivity analyses we found an association between low fructosamine and smoking and adjustment for smoking further attenuated the association between low fructosamine and mortality. Conclusion: Low levels of fructosamine in individuals without diabetes were found to be associated with increased mortality. Smoking and chronic inflammation seem to at least partially explain this association but an independent contribution by low fructosamine cannot be excluded.
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  • Sundborg, E, et al. (författare)
  • Cross-cultural adaptation of an intimate partner violence questionnaire
  • 2012
  • Ingår i: Clinical nursing research. - : SAGE Publications. - 1552-3799 .- 1054-7738. ; 21:4, s. 450-466
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to describe the translation and the cross-cultural adaptation process of questionnaire about intimate partner violence (IPV). IPV is a serious threat to women’s health. There is a need for instruments to measure the results of educational interventions. The Violence Against Women Health Care Provider Survey was found suitable for translation and adaptation to the Swedish cultural context. A five-step process according to Guillemin et al. was followed: (a) translation by independent translators, (b) back translation of each translation independently from each other, (c) committee review with multidisciplinary members produces the final version, and (d) pretesting to ensure equivalence between source and final version, and (e) weighting scores. The Swedish version consisted of the same number of items as the original. The results indicated that the questionnaire can be used in Sweden to measure the effectiveness of IPV training programs.
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  • Sundborg, E, et al. (författare)
  • Psychometric Testing of an Instrument About Intimate Partner Violence
  • 2018
  • Ingår i: Clinical nursing research. - : SAGE Publications. - 1552-3799 .- 1054-7738. ; 27:4, s. 497-515
  • Tidskriftsartikel (refereegranskat)abstract
    • This study used step-by-step exploratory factor analysis in the framework of confirmatory factor analysis (EFA/CFA) to evaluate the psychometric properties of the translated and culturally adapted Swedish version of “The Violence Against Women Health Care Provider Survey.” The Swedish version of the instrument was needed to measure district nurses’ preparedness to encounter women exposed to intimate partner violence. In the first step of EFA/CFA, the eight-factor model was confirmed. The item-total correlations ranged from .22 to 1.01, and Cronbach’s alphas from .68 to .71. After removing four items, the corrected item-total correlations ranged from .40 to .97. On the basis of the analysis, we concluded that the Swedish version of the instrument is valid and reliable for evaluating the preparedness of district nurses in Sweden to encounter women exposed to intimate partner violence.
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  • Uzunel, E, et al. (författare)
  • Association between self-rated health and the risk of hip fracture and mortality in a cohort of older women during a 10-year follow-up
  • 2021
  • Ingår i: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 16:3, s. e0247924-
  • Tidskriftsartikel (refereegranskat)abstract
    • Fragility fracture of the hip is associated with reduced functional status and mortality. Poor self-rated health (SRH) might be such an indicator. Our aim was to study if SRH was associated with hip fractures and all-cause mortality within the next 10 years in community-dwelling older women. A population-based sample of 350 women aged between 69 and 79 years (median 72.4) assessed their SRH by answering the question “How would you rate your health right now” by putting a mark on a visual-analogue scale (0–100 mm). Information on hip fracture and mortality over the next 10 years was retrieved from health care registers. The association between SRH and hip fracture and all-cause mortality was tested with a Cox proportional hazards regression model. SRH was divided into low, intermediate, and high (reference) assessed SRH. During the study, 40 hip fractures and 72 deaths occurred. The median value of SRH was 62 mm (IQR 50–81 mm). The age-adjusted hazard ratio (HR) for hip fracture was significantly higher in the group with low and intermediate SRH; HR: 3.17 (95% CI 1.25–8.01), and HR: 2.75 (95% CI 1.08–7.04), compared with high SRH. Adding bone mineral density (at the femoral neck) gave even greater risk. We did not find the hypothesized association between SRH and mortality. In our study, SRH indicated a higher risk of future hip fracture in older women. SRH might be a marker that could add information about the risk of hip fracture independently of bone mineral density.
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