| 1. |
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
- Almeida, MLS, et al.
(författare)
-
Ruthenium(II)-catalyzed Oppenauer-type oxidation of secondary alcohols
- 1996
-
Ingår i: CHEMISTRY-A EUROPEAN JOURNAL. - : WILEY-V C H VERLAG GMBH. ; 2:12
-
Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Highly efficient ruthenium-catalyzed Oppenauer-type oxidations of secondary alcohols to ketones have been developed. The catalytic system consists of [(PPh(3))(3)RuCl2] (1) and K2CO3 or [(C(4)Ph(4)COHOCC(4)Ph(4))(mu-H)(CO)(4)Ru-2] (2) in refluxing aceton
|
|
| 5. |
- Shi, W, et al.
(författare)
-
Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity
- 2006
-
Ingår i: Journal of Coordination Chemistry. - : Informa UK Limited. - 1026-7441 .- 0095-8972 .- 1029-0389. ; 59:2, s. 119-130
-
Tidskriftsartikel (refereegranskat)abstract
- The complex [Mn-III(HL)(L)(py)(CH3OH)](CH3OH)-C-. (H2L=2-ortho-hydroxyphenylbenzimidazole, py pyridine), 1, has been characterized spectroscopically and by X-ray crystallography. The complex is triclinic, space group P-1(-) with a = 10.396(2), b = 10.7340(10), c = 15.193(2) angstrom, alpha = 73.193(4)degrees, beta = 76.283(8)degrees, gamma = 61.400(40)degrees, V = 1415.1(4)angstrom(3), Z = 2, D-c = 1.445 Mg m(-3), M-r = 615.56, mu = 0.515 mm(-1), F(000) = 640, R = 0.0631, wR = 0.1525. Manganese is six-coordinate in an N3O3 ligand sphere created by two bidentate H2L ligands and solvent molecules with a slightly distorted, axially elongated octahedral geometry. Electronic absorption spectra show pi-pi* and Ligand Metal Charge Transfer (LMCT) transitions in the UV region and d-d transitions in the visible region. Solvent molecules coordinated to the Mn(III) ion in the crystal are thought to retain their coordination in solution. It is shown that 1 has reaction activity with the superoxide ion, as indicated by inhibition of pyrogallol autoxidation and by spin trapping electron paramagnetic resonance (EPR) spectroscopy. The N3O3 ligand set in 1 is similar to that in native MnSOD (superoxide dismutatase) in the substrate-bound state. The correlation between the ligand set in 1 and its reaction with the superoxide ion is discussed.
|
|
| 6. |
- van Zuydam, NR, et al.
(författare)
-
A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes
- 2018
-
Ingår i: Diabetes. - : American Diabetes Association. - 1939-327X .- 0012-1797. ; 67:7, s. 1414-1427
-
Tidskriftsartikel (refereegranskat)abstract
- Identification of sequence variants robustly associated with predisposition to diabetic kidney disease (DKD) has the potential to provide insights into the pathophysiological mechanisms responsible. We conducted a genome-wide association study (GWAS) of DKD in type 2 diabetes (T2D) using eight complementary dichotomous and quantitative DKD phenotypes: the principal dichotomous analysis involved 5,717 T2D subjects, 3,345 with DKD. Promising association signals were evaluated in up to 26,827 subjects with T2D (12,710 with DKD). A combined T1D+T2D GWAS was performed using complementary data available for subjects with T1D, which, with replication samples, involved up to 40,340 subjects with diabetes (18,582 with DKD). Analysis of specific DKD phenotypes identified a novel signal near GABRR1 (rs9942471, P = 4.5 × 10−8) associated with microalbuminuria in European T2D case subjects. However, no replication of this signal was observed in Asian subjects with T2D or in the equivalent T1D analysis. There was only limited support, in this substantially enlarged analysis, for association at previously reported DKD signals, except for those at UMOD and PRKAG2, both associated with estimated glomerular filtration rate. We conclude that, despite challenges in addressing phenotypic heterogeneity, access to increased sample sizes will continue to provide more robust inference regarding risk variant discovery for DKD.
|
|
| 7. |
|
|
| 8. |
- Zhu, YC, et al.
(författare)
-
Demographic Factors Associated With Leading Causes of Injury Mortality in Ningbo, China: 2004-2013
- 2016
-
Ingår i: Asia-Pacific journal of public health. - : SAGE Publications. - 1941-2479 .- 1010-5395. ; 28:8, s. 706-716
-
Tidskriftsartikel (refereegranskat)abstract
- Injuries have emerged as a crucial public health concern in China. Data were obtained from the death registry system in Ningbo during 2004-2013. Mortality rates resulting from all injuries and the 6 most common types of injuries were analyzed to identify time trends using linear regression models on both the absolute scale and log scale. A decreased male to female ratio and increasing age were observed among the total injury deaths. The annual all-injury mortality rates declined considerably during the observation period. Injury mortality rates for motor vehicle traffic crashes, drowning, and suicide all showed a deceasing trend; however, only mortality from falls showed an increasing trend. There was a sharp increasing trend among females, with a disproportionate number of falls. The injury patterns in Ningbo are mostly comparable to those in high-income countries. Appropriate preventive strategies should be urgently tailored to control this aggressive evolution in older individuals and females.
|
|
