| 1. |
- Lu, Quanming, et al.
(författare)
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Features of separatrix regions in magnetic reconnection : Comparison of 2-D particle-in-cell simulations and Cluster observations
- 2010
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Ingår i: Journal of Geophysical Research. - 0148-0227 .- 2156-2202. ; 115:11
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Tidskriftsartikel (refereegranskat)abstract
- In collisionless magnetic reconnection, the in-plane Hall currents are carried mainly by the magnetized electrons. The in-plane Hall currents are directed toward the X line along the magnetic field lines just inside the separatrices and away from the X line along the separatrices. Such a current system leads to the quadrupole out-of-plane magnetic field with the peaks between the regions carrying the in-plane currents. Simultaneously, the electron flow toward the X line along the separatrices causes electron density depletions along the separatrices. In this paper, the features of separatrix regions in magnetic reconnection and the relations between the electron density depletions and the out-of-plane magnetic field are investigated with both two-dimensional particle-in-cell simulations and Cluster observations. We conclude that the electron density depletions are formed because of the magnetic mirror, and they are outside the peaks of the out-of-plane magnetic field. Such a theoretical prediction is confirmed by both simulations and observations.
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| 2. |
- Wang, Lin, et al.
(författare)
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A novel extraction approach and unique physicochemical properties of gelatin from the swim bladder of sturgeon
- 2021
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Ingår i: Journal of the Science of Food and Agriculture. - : John Wiley & Sons. - 0022-5142 .- 1097-0010. ; 101:7, s. 2912-2919
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Gelatin is traditionally produced from mammals and widely applied in the food industry. The production is tedious, time-consuming and environment-unfriendly, while the application is restricted because of zoonosis risk and religious sentiment.RESULTS: Gelatin was extracted by hot water from sturgeon swim bladder after defatting with alcohol and hexane. The yield reached to 94.15% under the optimized conditions of 50 degrees C, 30 min and 10 mL g(-1). Its amino acid and subunit profiles were similar to type I collagen. Compared to commercial porcine, bovine and piscine gelatins, it exhibited higher whiteness (3.38), emulsion activity (171.76 m(2) g(-1)), gel strength (853.23 g), water-holding capacity (92.37%) and viscoelasticity (0.03). But the transmittance (40.56% at 450 nm and 59.07% at 620 nm), emulsion stability (30.09 min), foam expansion (203.00) and stability (26.92), gelling (16.88 degrees C) and melting temperature (21.80 degrees C) were lower. While the pH (6.87) and viscosity (28.60 mPa s) were moderate. Moreover, it made better hydrogels and nanofibers.CONCLUSION: Gelatin was extracted from sturgeon swim bladder using a clean and efficient approach, and exhibited unique properties and great potential for the food industry.
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| 3. |
- Gao, Ruichang, et al.
(författare)
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Sturgeon hydrolysates alleviate DSS-induced colon colitis in mice by modulating NF-kappa B, MAPK, and microbiota composition
- 2020
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Ingår i: Food & Function. - : ROYAL SOC CHEMISTRY. - 2042-6496 .- 2042-650X. ; 11:8, s. 6987-6999
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Tidskriftsartikel (refereegranskat)abstract
- Sturgeon muscle byproduct collected after caviar production is usually not fully utilized, and sometimes may be discarded, thus causing a lot of waste. Yet dietary protein hydrolysates, which may be derived from sturgeon muscle, have been reported to have versatile beneficial biological activities. Studying the biological activities of sturgeon muscle-derived hydrolysates holds much promise for adding value to sturgeon. The current study aimed to study the therapeutic anti-inflammatory effects of sturgeon muscle-derived hydrolysates and the underlying mechanisms. The administration of sturgeon hydrolysates (SH) significantly decreased the severity of DSS-induced damage, evidenced by increased body weight, colon length, and decreased disease activity index (DAI) and histological scores. SH also inhibited myeloperoxidase (MPO) activity and reduced the serum levels of IL-6, IL-1 beta, and TNF-alpha. Western blotting results revealed that SH suppressed DSS-induced activation of the NF-kappa B and MAPK pathways in the colon. Furthermore, SH partially restored the alteration of the gut microbiota in colitic mice. SH increased the Bacteroidetes/Firmicutes ratio and the relative abundance of Ruminococcaceae, Porphyromonadaceae, and Bacteroidetes S24-7, while decreased the abundance of potentially harmful bacteria Erysipelotrichaceae and Enterococcaceae. These results suggest that SH inhibited DSS-induced colitis by regulating the NF-kappa B and MAPK pathways and modulating microbiota composition.
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| 4. |
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| 5. |
- Rich, Rebecca L., et al.
(författare)
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A global benchmark study using affinity-based biosensors
- 2009
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Ingår i: Analytical Biochemistry. - : Elsevier BV. - 0003-2697 .- 1096-0309. ; 386:2, s. 194-216
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Tidskriftsartikel (refereegranskat)abstract
- To explore the variability in biosensor studies, 150 participants from 20 countries were given the same protein samples and asked to determine kinetic rate constants for the interaction. We chose a protein system that was amenable to analysis using different biosensor platforms as well as by users of different expertise levels. The two proteins (a 50-kDa Fab and a 60-kDa glutathione S-transferase [GST] antigen) form a relatively high-affinity complex, so participants needed to optimize several experimental parameters, including ligand immobilization and regeneration conditions as well as analyte concentrations and injection/dissociation times. Although most participants collected binding responses that could be fit to yield kinetic parameters, the quality of a few data sets could have been improved by optimizing the assay design. Once these outliers were removed, the average reported affinity across the remaining panel of participants was 620 pM with a standard deviation of 980 pM. These results demonstrate that when this biosensor assay was designed and executed appropriately, the reported rate constants were consistent, and independent of which protein was immobilized and which biosensor was used.
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