↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Wang ZJ.) "

Sökning: WFRF:(Wang ZJ.)

Resultat 1-10 av 99

Sortera/gruppera träfflistan

Sortering: Träffar per sida:

Numrering	Referens	Omslagsbild	Hitta
1.	Jakobsson, J., et al. (författare) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 2021 Ingår i: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 17:1, s. 1-382 Tidskriftsartikel (refereegranskat)
2.	Ahmad, T, et al. (författare) Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries 2016 Ingår i: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 117:5, s. 601- Tidskriftsartikel (refereegranskat)
3.	Ahmad, T, et al. (författare) In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study 2017 Ingår i: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. - : Elsevier BV. - 1532-2157 .- 0748-7983. ; 43:12, s. 2324-2332 Tidskriftsartikel (refereegranskat)
4.	Ahmad, T, et al. (författare) Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery 2017 Ingår i: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 119:2, s. 258-266 Tidskriftsartikel (refereegranskat)
5.	Abbafati, C, et al. (författare) Five insights from the Global Burden of Disease Study 2019 2020 Ingår i: Lancet (London, England). - 1474-547X .- 0140-6736. ; 396:10258, s. 1135-1159 Tidskriftsartikel (refereegranskat)
6.	Niemi, MEK, et al. (författare) 2021 swepub:Mat__t
7.	Callaway, EM, et al. (författare) A multimodal cell census and atlas of the mammalian primary motor cortex 2021 Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 598:7879, s. 86-102 Tidskriftsartikel (refereegranskat)abstract Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network (BICCN). This was achieved by coordinated large-scale analyses of single-cell transcriptomes, chromatin accessibility, DNA methylomes, spatially resolved single-cell transcriptomes, morphological and electrophysiological properties and cellular resolution input–output mapping, integrated through cross-modal computational analysis. Our results advance the collective knowledge and understanding of brain cell-type organization1–5. First, our study reveals a unified molecular genetic landscape of cortical cell types that integrates their transcriptome, open chromatin and DNA methylation maps. Second, cross-species analysis achieves a consensus taxonomy of transcriptomic types and their hierarchical organization that is conserved from mouse to marmoset and human. Third, in situ single-cell transcriptomics provides a spatially resolved cell-type atlas of the motor cortex. Fourth, cross-modal analysis provides compelling evidence for the transcriptomic, epigenomic and gene regulatory basis of neuronal phenotypes such as their physiological and anatomical properties, demonstrating the biological validity and genomic underpinning of neuron types. We further present an extensive genetic toolset for targeting glutamatergic neuron types towards linking their molecular and developmental identity to their circuit function. Together, our results establish a unifying and mechanistic framework of neuronal cell-type organization that integrates multi-layered molecular genetic and spatial information with multi-faceted phenotypic properties.
8.	Li, ZQ, et al. (författare) Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia 2017 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:11, s. 1576- Tidskriftsartikel (refereegranskat)
9.	Ma, Q, et al. (författare) ZnT8 loss-of-function accelerates functional maturation of hESC-derived β cells and resists metabolic stress in diabetes 2022 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 13:1, s. 4142- Tidskriftsartikel (refereegranskat)abstract Human embryonic stem cell-derived β cells (SC-β cells) hold great promise for treatment of diabetes, yet how to achieve functional maturation and protect them against metabolic stresses such as glucotoxicity and lipotoxicity remains elusive. Our single-cell RNA-seq analysis reveals that ZnT8 loss of function (LOF) accelerates the functional maturation of SC-β cells. As a result, ZnT8 LOF improves glucose-stimulated insulin secretion (GSIS) by releasing the negative feedback of zinc inhibition on insulin secretion. Furthermore, we demonstrate that ZnT8 LOF mutations endow SC-β cells with resistance to lipotoxicity/glucotoxicity-triggered cell death by alleviating endoplasmic reticulum (ER) stress through modulation of zinc levels. Importantly, transplantation of SC-β cells with ZnT8 LOF into mice with preexisting diabetes significantly improves glycemia restoration and glucose tolerance. These findings highlight the beneficial effect of ZnT8 LOF on the functional maturation and survival of SC-β cells that are useful as a potential source for cell replacement therapies.
10.	Ong, KL, et al. (författare) Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 2023 Ingår i: Lancet (London, England). - 1474-547X .- 0140-6736. ; 402:10397, s. 203-234 Tidskriftsartikel (refereegranskat)

Skapa referenser, mejla, bekava och länka

Länka till träfflistan

Resultat 1-10 av 99

Avgränsa träffmängd

Typ av publikation: tidskriftsartikel (93); konferensbidrag (4); forskningsöversikt (1)

Typ av innehåll: refereegranskat (87); övrigt vetenskapligt/konstnärligt (11)

Författare/redaktör: Mokdad, AH (29); Fischer, F (28); Singh, JA (28); Ilesanmi, OS (27); Arabloo, J (26); Kisa, A (26); visa fler...; Olagunju, AT (26); Rawaf, S (26); Samy, AM (26); Shaikh, MA (26); Koyanagi, A (25); Mohammed, S (25); Hay, SI (24); Hosseinzadeh, M (24); Jonas, JB (24); Mestrovic, T (24); Monasta, L (24); Bijani, A (23); Dandona, R (23); Jha, RP (23); Naghavi, M (23); Gupta, R. (22); Alipour, V (22); Dandona, L (22); Farzadfar, F (22); Miller, TR (22); Radfar, A (22); Renzaho, AMN (22); Sathian, B (22); Tovani-Palone, MR (22); Chu, DT (21); Filip, I (21); Fukumoto, T (21); Khader, YS (21); Kim, YJ (21); Majeed, A (21); Mansournia, MA (21); Nangia, V (21); Rawaf, DL (21); Aljunid, SM (20); Banach, M (20); Bhattacharyya, K (20); Eskandarieh, S (20); Ghashghaee, A (20); Haj-Mirzaian, A (20); Jakovljevic, M (20); Jozwiak, JJ (20); Kumar, M (20); Mendoza, W (20); Sahebkar, A (20); visa färre...

Lärosäte: Karolinska Institutet (96); Uppsala universitet (9); Lunds universitet (9); Högskolan Dalarna (8); Göteborgs universitet (4); Umeå universitet (2); visa fler...; Stockholms universitet (2); Linköpings universitet (2); Jönköping University (2); Chalmers tekniska högskola (2); Mittuniversitetet (1); Sveriges Lantbruksuniversitet (1); visa färre...

Språk: Engelska (99)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (24); Naturvetenskap (2); Samhällsvetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - Nationella bibliotekssystem
LIBRIS.kb.se

pil uppåt

Stäng

Kopiera och spara länken för att återkomma till aktuell vy