| 1. |
|
|
| 2. |
- Henriksson, Malin, et al.
(författare)
-
Effects of exercise on symptoms of anxiety in primary care patients: A randomized controlled trial.
- 2022
-
Ingår i: Journal of affective disorders. - : Elsevier BV. - 1573-2517 .- 0165-0327. ; 297, s. 26-34
-
Tidskriftsartikel (refereegranskat)abstract
- There is a need for high-quality research regarding exercise interventions for persons with anxiety disorders. We investigate whether a 12-week exercise intervention, with different intensities, could reduce anxiety symptoms in patients with anxiety disorders.286 patients were recruited from primary care in Sweden. Severity of symptoms was self-assessed using the Beck Anxiety Inventory (BAI) and the Montgomery Åsberg Depression Rating Scale (MADRS-S). Participants were randomly assigned to one of two group exercise programs with cardiorespiratory and resistance training and one control/standard treatment non-exercise group, with 1:1:1 allocation.Patients in both exercise groups showed larger improvements in both anxiety and depressive symptoms compared to the control group. No differences in effect sizes were found between the two groups. To study a clinically relevant improvement, BAI and MADRS-S were dichotomized with the mean change in the control group as reference. In adjusted models the odds ratio for improved symptoms of anxiety after low-intensity training was 3.62 (CI 1.34-9.76) and after moderate/high intensity 4.88 (CI 1.66-14.39), for depressive symptoms 4.96 (CI 1.81-13.6) and 4.36 (CI 1.57-12.08) respectively. There was a significant intensity trend for improvement in anxiety symptoms.The use of self-rating measures which bears the risk of an under- or overestimation of symptoms.A 12-week group exercise program proved effective for patients with anxiety syndromes in primary care. These findings strengthen the view of physical exercise as an effective treatment and could be more frequently made available in clinical practice for persons with anxiety issues.
|
|
| 3. |
- Moghadas, Shahab, et al.
(författare)
-
Snowmelt modeling in urban areas : sensitivity analysis of the energy and mass balance method
- 2012
-
Konferensbidrag (refereegranskat)abstract
- Flooding is one of the main concerns in seeking safe and sustainable urban areas. In many cases the design criteria are based on intense rainfall. It is, therefore, assumed that the peak flow in cities’ drainage systems is due to heavy and fast rainfalls. However snowmelt pattern could be more important for places with cold climate; therefore the need of a better snowmelt and runoff simulation becomes more important particularly when the effects of climate change needs to be considered. Two main methods are basically used for urban snowmelt simulation i.e. temperature index and energy budged methods. Studies done previously show that the energy balance method gives a better estimation for volume and time compare to the temperature index. For urban areas though, it is argued that the data demanding of the energy balance method can be a disadvantage and it could affect the model precision. However, the advances in geographical information systems (GIS) and the requirement for better time resolution than daily have increased the tendency of applying it for urban snow melt. There are couples of studies during recent years e.g. (Ho& Valeo 2005) applying energy budget method in urban areas, even though the efforts basically focused on developing routines and comparing it with the degree day method. There is still a gap in parameter sensitivity analysis especially with two main features of urban snowmelt modeling; firstly, the importance of input data along with difficulties in providing them; and secondly the classification of snow in urban areas based on snow properties. These two concerns were the motives to go one step ahead and to conduct a sensitivity analysis. The aim of the study is therefore to investigate the dependency of the simulation results to the different model parameters as built-in parameters and input data. Such analysis eventually can be used for snow classification which along with GIS technology can provide a reliable platform to simulate snowmelt over an urban catchment more precisely than what the current models are capable of today. Here in this study, a model namely Utah Energy Balance Snow Model (UEB) is used. The model uses a complete energy and mass balance routine to simulate snow accumulation and melt at a point scale. Except using the measured climatic values to run the model, the routines in this model has the capability of producing (simulating) solar radiation and albedo if the measured values are not available. The model has simulated the snow accumulation and melts in rural area with reasonable accuracy in previous studies i.e. (Tarboton et al. 1995). For this research, three snow deposits from 1991 and 1992 are taken to calibrate the model with. The pilot snow packs are identical to municipal snow deposit with density more than natural snow, around 700 Kg/m3. The snowmelt runoff has been measure between March and Jun 1991 and 1992. The necessary input values are collected from Meteorological and Hydrological Institute (SMHI) for the same periods. All input parameters are available on hourly and 3 hourly periods. The method is to run the model with real values collected from SMHI and calibrate it versus the measured data. The model is run using modified parameters to investigate the possible change in the simulation result. Eventually an analysis is done on each parameter and the dependency of the model. An analysis also is done by running the model with different time resolution, i.e. hourly, 3-hourly, and 6-hourly and to investigate the effect of time span in modeling snowmelt and simulation precision.
|
|
| 4. |
- Nyberg, Anna, et al.
(författare)
-
Destructive managerial leadership and psychological well-being among employees in Swedish, Polish, and Italian hotels
- 2011
-
Ingår i: Work. - : IOS Press. - 1051-9815 .- 1875-9270. ; 39:3, s. 267-281
-
Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this cross-sectional exploratory study was to investigate destructive managerial leadership in the hotel industry in Sweden, Poland, and Italy in relation to psychological well-being among employees.Methods and Participants: 554 questionnaires were collected from employees in all occupational groups within hotels. The Copenhagen Psychosocial Questionnaire (COPSOQ) measured working conditions, particularly iso-strain or high work demands combined with low control and poor social support, and psychological well-being, defined in terms of mental health, vitality, and behavioural stress. Items adapted from the Global Leadership and Organisational Behaviour Effectiveness (GLOBE) research program questionnaire measured autocratic, malevolent, and self-centred leadership styles. Differences in ratings between countries were estimated, as well as the relationship between destructive managerial leadership on an organisation level and employee psychological well-being on an individual level. The relationship between destructive leadership and psychological well-being among employees was adjusted for employees' reported iso-strain.Results: Autocratic and malevolent leadership were at the organisation level related to low vitality among employees and self-centred leadership was significantly associated with poormental health, low vitality, and high behavioural stress. Autocratic and malevolent leadership were more strongly related to iso-strain than was self-centred leadership. Variations in leadership practice between countries were seen in autocratic and malevolent leadership.Conclusion: This exploratory study suggests a significant association between destructive managerial leadership on the organisation level and poor psychological well-being among employees on an individual level. Interventions to decrease iso-strain and enhance psychological well-being among employees could be directed at an organisation level.
|
|
| 5. |
- Nyberg, Jenny, 1976, et al.
(författare)
-
Anxiety severity and cognitive function in primary care patients with anxiety disorder: a cross-sectional study.
- 2021
-
Ingår i: BMC psychiatry. - : Springer Science and Business Media LLC. - 1471-244X. ; 21:1
-
Tidskriftsartikel (refereegranskat)abstract
- Deficits in cognitive performance are reported in patients with anxiety disorders, but research is limited and inconsistent. We aimed to investigate cross-sectional associations between cognitive function, with focus on executive function, and anxiety severity in primary care patients diagnosed with anxiety disorders.189 Swedish patients aged 18-65years (31% men) with anxiety disorders diagnosed according to Mini International Neuropsychiatric Interview were included. Severity of anxiety was assessed using Beck Anxiety Inventory self-assessment scale. Digit span, block design and matrix reasoning tests from the Wechsler Adult Intelligence Scale IV, and the design fluency test from the Delis-Kaplan Executive Function System were used. Multivariable linear regression models were applied to investigate the relationship of anxiety severity and cognitive functioning. Comparisons were also performed to a normed non-clinical population, using the Wilcoxon signed rank test.More severe anxiety was associated with lower digit span test scores (R2=0.109, B=-0.040, p=0.018), but not with block design, matrix reasoning or design fluency tests scores, after adjustment for comorbid major depression in a multivariable model. When compared to a normed population, patients with anxiety performed significantly lower on the block design, digit span forward, digit span sequencing and matrix reasoning tests.Severity of anxiety among patients with anxiety disorder was associated with executive functions related to working memory, independently of comorbid major depression, but not with lower fluid intelligence. A further understanding of the executive behavioral control in patients with anxiety could allow for more tailored treatment strategies including medication, therapy and interventions targeted to improve specific cognitive domains.
|
|
| 6. |
- Öhrnell Malekzadeh, Behnosh, et al.
(författare)
-
Effects of implant-delivered insulin on bone formation in osteoporotic rats
- 2018
-
Ingår i: Journal of Biomedical Materials Research - Part A. - : Wiley. - 1549-3296 .- 1552-4965. ; 106:9, s. 2472-80
-
Tidskriftsartikel (refereegranskat)abstract
- © 2018 Wiley Periodicals, Inc. Osteoporosis is a major cause of age-related fractures. Healing complications in osteoporotic patients are often associated with increased mortality and morbidity. Stimulation of the implant-adjacent bone could be beneficial in terms of the surgical outcome. Over the past decade, numerous investigations have implicated insulin in normal bone growth, and recent studies have described the advantages of administering insulin locally to increase bone formation. Therefore, we hypothesized that insulin-coated titanium implants would increase bone formation in osteoporotic animals. The aim of this study was to evaluate the effects of insulin delivered from an implant surface on bone-related gene expression and bone formation in osteoporotic rats. Characterizations of the surfaces of insulin-coated and control implants were performed using ellipsometry and interferometry. Forty ovariectomized and four healthy Sprague Dawley rats were used and implants were inserted in the tibias. The systemic effect of insulin was assessed by measuring the blood glucose levels and total body weight. The animals were sacrificed either 1 day or 3 weeks postimplantation. Implant-adherent cells were analyzed by quantitative real-time PCR, and the bone adjacent to the implants was examined by microcomputed tomography and histomorphometry. The insulin-coated implants had no systemic effects. The insulin-coated samples demonstrated significantly lower expression of the gene for interleukin 1β (p=0.019) at 1 day, and significantly exhibited more periosteal callus (p=0.029) at 3 weeks. Locally delivered insulin has potential for promoting bone formation and it exerts potentially anti-inflammatory effects in osteoporotic rats.
|
|
| 7. |
- Al-Taai, Nameer, et al.
(författare)
-
A Superimposition-Based Cephalometric Method to Quantitate Craniofacial Changes
- 2021
-
Ingår i: International Journal of Environmental Research and Public Health. - : MDPI AG. - 1660-4601 .- 1661-7827. ; 18
-
Tidskriftsartikel (refereegranskat)abstract
- To assess the craniofacial changes related to growth and/or to orthodontic and orthognathic treatments, it is necessary to superimpose serial radiographs on stable structures. However, conventional superimposition provides only a graphical illustration of these changes. To increase the precision of growth and treatment evaluations, it is desirable to quantitate these craniofacial changes. The aims of this study were to (1) evaluate a superimposition-based cephalometric method to process numerical data for craniofacial growth changes and (2) identify a valid, reliable, and feasible method for superimposition. Forty pairs of cephalograms were analyzed at T1 and T2 (mean age 9.9 and 15.0 years, respectively). The superimposition-based cephalometric method involved relating the sagittal and vertical measurements on the T2 radiographs to the nasion and sella landmarks on the T1 radiographs. Validity and reliability were evaluated for three superimposition methods: the sella-nasion (SN); the tuberculum sella-wing (TW); and Bjork's structural. Superimposition-based cephalometrics can be used to quantify craniofacial changes digitally. The numerical data from the superimposition-based cephalometrics reflected a graphical illustration of superimposition and differed significantly from the data acquired through conventional cephalometrics. Superimposition using the TW method is recommended as it is valid, reliable, and feasible.
|
|
| 8. |
- Al-Taai, Nameer, et al.
(författare)
-
Craniofacial changes from 13 to 62 years of age
- 2022
-
Ingår i: European Journal of Orthodontics. - : Oxford University Press (OUP). - 0141-5387 .- 1460-2210. ; 44:5, s. 556-565
-
Tidskriftsartikel (refereegranskat)abstract
- Background In long-term studies of orthodontic, orthognathic, and prosthodontic treatments, control subjects are needed for comparison. Objectives To study the craniofacial (skeletal, soft tissue, and dental) changes that occur in untreated subjects with normal occlusion between 13 and 62 years of age. Materials/Methods Thirty subjects with a Class I normal occlusion and harmonious facial profile were studied. X-ray examinations were performed at 13 (T1), 16 (T2), 31 (T3), and 62 (T4) years of age, and data were obtained from cephalograms. In total, 53 angular and linear parameters were measured using superimposition-based and conventional cephalometric methods to describe the craniofacial changes. Results The jaws showed significant anterior growth from T1 to T2, and significant retrognathism from T3 to T4. The anterior face height and jaw dimensions increased significantly until T3. Significant posterior rotation of the mandible and opening of the vertical jaw relation, in addition to significant retroclination of the incisors and straightening of the facial profile, were found from T3 to T4. Limitations Given the small sample size at T4, it was not possible to analyse the gender dimension. Conclusions/Implications Craniofacial changes continue up to the sixth decade of life. These changes are consistent, albeit to a lesser extent, with the adolescent growth patterns for most of the studied parameters, with the exceptions of incisor inclination, sagittal jaw position, vertical jaw relation and inclination, and posterior face height.
|
|
| 9. |
- Al-Taai, Nameer, 1975-
(författare)
-
Dentoalveolar and craniofacial changes from early adolescence to late adulthood
- 2022
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Objectives: Study I: To evaluate the reliability and validity of different superimposition methods and to increase the precision with which craniofacial growth and treatment can be quantified. Study II: To explore the craniofacial changes that occur from early adolescence to late adulthood. Study III: To assess the impact of premolar extractions on dentoskeletal and facial morphologies up to late adulthood. Study IV: In a 50-year follow-up, to study how early extraction of four premolars affects the development of age-related lower incisor crowding. Materials and Methods: Study I: Forty pairs of cephalograms were analysed at mean ages of 9.9 (T1) and 15.0 (T2) years. Three superimposition methods were assessed: the Sella-Nasion (SN); the Tuberculum Sella-Wing (TW); and Björk’s structural. Björk’s structural method was performed using three techniques: direct, tracing template, and subtraction. Study II: Thirty subjects with a Class I normal occlusion and harmonious facial profile were investigated. Study data were obtained from cephalograms performed at 12 (T1), 15 (T2), 30 (T3), and 62 (T4) years of age. The craniofacial changes were assessed using superimposition-based and conventional cephalometric methods. Study III: Two groups were included. The Extraction group (N=30 with Class I crowding malocclusion) had their first premolars extracted at a mean age of 11.5 years, without subsequent orthodontic treatment. The Control group included 30 untreated subjects with Class I normal occlusion. Study data were obtained from cephalograms performed at 12 (T1), 15 (T2), 30 (T3) and 62 (T4) years of age. The dentoskeletal and soft tissue changes were assessed using superimposition-based and conventional cephalometric methods. Study IV: Two groups were included. The Extraction group (N=24 with Class I crowding malocclusion) that had their first premolars extracted at mean age of 11.5 years, without subsequent orthodontic treatment. The Control group included 21 untreated subjects with Class I normal occlusion. Study data were obtained from dental casts and cephalograms performed at mean ages of 11.4 and 13.0 years, for the two groups, respectively (T1), and at mean ages of 30.9 years (T2) and 61.7 years (T3).Results: Study I: The numerical data from the superimposition-based cephalometrics reflected a graphical illustration of superimposition and differed significantly from the data acquired using conventional cephalometrics. While there were no significant differences between the TW method and Björk’s three techniques, significant differences were found between the SN method and the other methods. Study II: The maxilla and mandible showed significant anterior growth from T1 to T2, and significant retrognathism from T3 to T4. The anterior facial height and jaw dimensions increased significantly until T3. From T3 to T4, significant posterior rotation of the mandible and opening of the vertical jaw relation were observed, in addition to significant retroclination of the upper incisors, decrease in lip prominence, and straightening of the facial profile. Study III: There were no significant differences between the Extraction and Control groups in terms of the skeletal sagittal relation, incisor inclination and protrusion (or for most of the soft tissue parameters) during the observation period. Study IV: The Extraction group showed significant improvement in the space deficiency of the lower teeth and no changes in the irregularity of the lower incisors up to late adulthood. In contrast, both the space deficiency of the lower teeth and irregularity of the lower incisors were significantly exacerbated in the Control group, up to late adulthood. Conclusions: The superimposition-based cephalometric method accurately generates numerical data for the craniofacial changes. Superimposition using the TW method is valid, reliable, and feasible, and is recommended to be used for superimposition-based cephalometrics. Moreover, craniofacial changes and development of lower incisor irregularity and crowding continue up to late adulthood in untreated subjects who were originally classified as having normal occlusion. For successful long-term outcomes, clinicians should therefore consider age-related changes in patients when planning for orthodontic, orthognathic, and prosthodontic treatments. Treatment with the extraction of four premolars alone in patients with Class I malocclusion with severe crowding does not impact the long-term dentoskeletal and soft tissue profile, and results in unchanged lower incisor alignment.
|
|
| 10. |
- Al-Taai, Nameer, et al.
(författare)
-
Dentoskeletal and soft tissue changes after treatment of crowding with premolar extractions: a 50-year follow-up
- 2023
-
Ingår i: European Journal of Orthodontics. - : Oxford University Press (OUP). - 0141-5387 .- 1460-2210. ; 45:1, s. 79-87
-
Tidskriftsartikel (refereegranskat)abstract
- Background The long-term effects on dentofacial morphology of interceptive treatment with premolar extractions, in the absence of subsequent orthodontic treatment, have not been fully explored. Objective The aim was to investigate the effects of premolar extractions (without subsequent orthodontic treatment) on the dentoskeletal and soft tissue profile of patients aged between 12 and 62 years with Class I malocclusion with severe crowding, as compared to untreated controls. Materials and methods The Extraction group (N = 30 with Class I crowding malocclusion) had their first premolars removed in early adolescence without subsequent orthodontic treatment. The Control group included 30 untreated subjects with Class I normal occlusion. Cephalograms were taken at 12 (T1), 15 (T2), 30 (T3), and 62 (T4) years of age. A superimposition-based cephalometric method was used to assess the dentoskeletal and soft tissue changes. Results There were no significant differences between the Extraction and Control groups in terms of skeletal sagittal relation, incisor inclination, and protrusion, or most of the soft tissue parameters throughout the observation period. However, significant differences were observed between the groups with respect to the vertical relations in T2-T3, such that the Extraction group showed more-pronounced decreases in the ML/NSL, ML/NL, and Gonial angles and more-pronounced increases in facial heights. Conclusions and implications Treatment for subjects with Class I malocclusion with severe crowding by the extraction of four premolars, without subsequent orthodontic treatment, does not affect the long-term dentoskeletal and soft tissue profile, as compared to an untreated Control group. The degree of crowding, rather than changes in dentofacial morphology, is crucial in deciding on extraction therapy.
|
|
