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Sökning: WFRF:(Wilhelm Claire)

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1.
  • Glomm, Wilhelm R., et al. (författare)
  • Europium(III)-cored fluorinated dendrimers at the air-water surface
  • 2007
  • Ingår i: Colloids and Surfaces A. - : Elsevier BV. - 0927-7757 .- 1873-4359. ; 299:03-jan, s. 186-197
  • Tidskriftsartikel (refereegranskat)abstract
    • A series of lanthanide (Eu3+) cored fluorinated dendrimers of generations I through 4 (G1-G4) have been studied with respect to their film-forming properties at the air-water surface. All dendrimers studied here formed stable films at the air-water surface. At the air-water surface, the dendrimers are likely to adopt asymmetric funnel-like conformations wherein the lanthanide core is directed towards the water surface and the fluorinated phenyl groups are directed away from the bulk phase. This hypothesis was further tested by addition of an electrolyte (0.01 M MgSO4) to the subphase. The added electrolyte was found to (i) advance the onset of network formation, as well as completion of monolayers, and (ii) increase the collapse pressure. Both features support the asymmetric conformation hypothesis, in that addition of an electrolyte promotes further conformational changes and shields electrostatic repulsion between lanthanide cores, thus allowing for closer packing of the molecules.
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3.
  • Rubia-Rodríguez, Irene, et al. (författare)
  • Whither Magnetic Hyperthermia? : A Tentative Roadmap
  • 2021
  • Ingår i: Materials. - : MDPI AG. - 1996-1944. ; 14:4
  • Tidskriftsartikel (refereegranskat)abstract
    • The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing have been seeking to push the forefront towards some new clinical trials. As many, they did not go at the expected pace. Today, fruitful international cooperation and the wisdom gain after a careful analysis of the lessons learned from seminal clinical trials allow us to have a future with better guarantees for a more definitive takeoff of this genuine nanotherapy against cancer. Deliberately giving prominence to a number of critical aspects, this opinion review offers a blend of state-of-the-art hints and glimpses into the future of the therapy, considering the expected evolution of science and technology behind magnetic hyperthermia.
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