| 1. |
- Dahlberg, Matz, et al.
(författare)
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Inledning
- 2013. - 1
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Ingår i: Välfärdstjänster i privat regi. - Stockholm : SNS förlag. - 9789186949471 ; , s. 21-32
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 2. |
- Dahlberg, Matz, et al.
(författare)
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Inledning
- 2013. - 1
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Ingår i: Välfärdstjänster i privat regi. - Stockholm : SNS förlag. - 9789186949471 ; , s. 221-230
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- I den här antologin har vi behandlat privatiseringar inom den svenska välfärdssektorn. Sedan slutet av 1980-talet har Sverige gått från ett nästan helt offentligt produktionssystem till ett system med en blandning av offentliga och privata utförare som konkurrerar med varandra. Valfrihet för brukarna har införts på flera områden. Vi har beskrivit hur framväxten av privat välfärdsproduktion sett ut och analyserat några centrala drivkrafter bakom denna utveckling.
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| 3. |
- Nörby, Ulrika, et al.
(författare)
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Drugs and Birth Defects: a knowledge database providing risk assessments based on national health registers
- 2013
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Ingår i: European Journal of Clinical Pharmacology. - : Springer Science and Business Media LLC. - 1432-1041 .- 0031-6970. ; 69:4, s. 889-899
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Tidskriftsartikel (refereegranskat)abstract
- To present concept, methods and use of a knowledge database providing assessments of potential fetal risks for all drugs on the Swedish market. Assessments of fetal risks are made primarily by analyzing prospective epidemiological data from the Swedish Medical Birth Register on drug intake in relation to birth outcome. This is complemented by evaluation of the scientific literature. Following standardized working procedures, a statement is compiled for each substance, which is also classified into one of three categories depending on the estimated risk level. The final documents include drug product names on the market, via linkage to a medicinal products register. The information is free and published on the website www.janusinfo.se. It can also be used as an integrated part of electronic health records. The database covers assessments of fetal risks for close to 1,250 medicinal drug substances on the Swedish market. Each year, 96,000 searches are made, which might be compared to the around 100,000 children born in Sweden yearly. Apart from the Swedish Physicians' Desk Reference (Fass), the database is the most commonly used resource among specialists within gynaecology and perinatal medicine for information on drugs during pregnancy. A non-commercial knowledge base with assessments of fetal risk of different drugs is valued by health care professionals and is used extensively in Sweden. Based on analyses of national health registers, the database provides unique information on teratogenic drug risks.
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| 4. |
- Nörby, Ulrika, et al.
(författare)
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Midwives' perception of using a knowledge base on fetal impact of drugs
- 2019
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Ingår i: MEDINFO 2019 : Health and Wellbeing e-Networks for All - Proceedings of the 17th World Congress on Medical and Health Informatics - Health and Wellbeing e-Networks for All - Proceedings of the 17th World Congress on Medical and Health Informatics. - 1879-8365 .- 0926-9630. - 9781643680026 ; 264, s. 1743-1744
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Konferensbidrag (refereegranskat)abstract
- A non-commercial knowledge base providing assessments of fetal risks of medicinal drugs is a useful tool in the everyday work of midwives. The information is freely available on the internet, and according to a questionnaire study, nearly 95% of the midwives are familiar with the database, 30% use the information weekly, and 80% express that it affects their medical decisions. A vast majority of the midwives also state that it is time-saving.
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| 5. |
- Nörby, Ulrika, et al.
(författare)
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Neonatal Morbidity After Maternal Use of Antidepressant Drugs During Pregnancy
- 2016
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Ingår i: Pediatrics. - : American Academy of Pediatrics (AAP). - 0031-4005 .- 1098-4275. ; 138:5
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: To estimate the rate of admissions to NICUs, as well as infants' morbidity and neonatal interventions, after exposure to antidepressant drugs in utero. METHODS: Data on pregnancies, deliveries, prescription drug use, and health status of the newborn infants were obtained from the Swedish Medical Birth Register, the Prescribed Drug Register, and the Swedish Neonatal Quality Register. We included 741 040 singletons, born between July 1, 2006, and December 31, 2012. Of the infants, 17 736 (2.4%) had mothers who used selective serotonin reuptake inhibitors (SSRIs) during pregnancy. Infants exposed to an SSRI were compared with nonexposed infants, and infants exposed during late pregnancy were compared with those exposed during early pregnancy only. The results were analyzed with logistic regression analysis. RESULTS: After maternal use of an SSRI, 13.7% of the infants were admitted to the NICU compared with 8.2% in the population (adjusted odds ratio: 1.5 [95% confidence interval: 1.4-1.5]). The admission rate to the NICU after treatment during late pregnancy was 16.5% compared with 10.8% after treatment during early pregnancy only (adjusted odds ratio: 1.6 [95% confidence interval: 1.5-1.8]). Respiratory and central nervous system disorders and hypoglycemia were more common after maternal use of an SSRI. Infants exposed to SSRIs in late pregnancy compared with early pregnancy had a higher risk of persistent pulmonary hypertension (number needed to harm: 285). CONCLUSIONS: Maternal use of antidepressants during pregnancy was associated with increased neonatal morbidity and a higher rate of admissions to the NICU. The absolute risk for severe disease was low, however.
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| 6. |
- Nörby, Ulrika, et al.
(författare)
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Perinatal outcomes after treatment with ADHD medication during pregnancy
- 2017
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Ingår i: Pediatrics. - : American Academy of Pediatrics (AAP). - 0031-4005 .- 1098-4275. ; 140:6
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: To analyze perinatal outcomes after maternal use of attention-deficit/ hyperactivity disorder (ADHD) medication during pregnancy. METHODS: The study included singletons born between 2006 and 2014 in Sweden. Data on prescription drug use, pregnancies, deliveries, and the newborn infants' health were obtained from the Swedish Medical Birth Register, the Prescribed Drug Register, and the Swedish Neonatal Quality Register. We compared infants exposed to ADHD medication during pregnancy with infants whose mothers never used these drugs and infants whose mothers used ADHD medication before or after pregnancy. Analyses were performed with logistic regression. RESULTS: Among 964 734 infants, 1591 (0.2%) were exposed to ADHD medication during pregnancy and 9475 (1.0%) had mothers treated before or after pregnancy. Exposure during pregnancy increased the risk for admission to a NICU compared with both no use and use before or after pregnancy (adjusted odds ratio [aOR], 1.5; 95% confidence interval [CI], 1.3-1.7; and aOR, 1.2; 95% CI, 1.1-1.4, respectively). Infants exposed during pregnancy had more often central nervous system-related disorders (aOR, 1.9; 95% CI, 1.1-3.1) and were more often moderately preterm (aOR, 1.3; 95% CI, 1.1-1.6) than nonexposed infants. There was no increased risk for congenital malformations or perinatal death. CONCLUSIONS: Treatment with ADHD medication during pregnancy was associated with a higher risk for neonatal morbidity, especially central nervous system-related disorders such as seizures. Because of large differences in background characteristics between treated women and controls, it is uncertain to what extent this can be explained by the ADHD medication per se.
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| 7. |
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| 8. |
- Nörby, Ulrika, et al.
(författare)
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Pregnant women's view on the Swedish internet resource Drugs and Birth Defects intended for health care professionals.
- 2015
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Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : Wiley. - 1600-0412 .- 0001-6349. ; 94:9, s. 960-968
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Tidskriftsartikel (refereegranskat)abstract
- Pregnant women often have questions concerning fetal effects of drugs but reliable information intended for them is limited. This study investigated how pregnant women perceive and value the scientific resource Drugs and Birth Defects (www.janusinfo.se/fosterpaverkan) and compared their opinions to those of health care professionals.
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