| 1. |
- Azevedo, Flavio, et al.
(författare)
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Social and moral psychology of COVID-19 across 69 countries
- 2023
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Ingår i: Scientific Data. - : NATURE PORTFOLIO. - 2052-4463. ; 10:1
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Tidskriftsartikel (refereegranskat)abstract
- The COVID-19 pandemic has affected all domains of human life, including the economic and social fabric of societies. One of the central strategies for managing public health throughout the pandemic has been through persuasive messaging and collective behaviour change. To help scholars better understand the social and moral psychology behind public health behaviour, we present a dataset comprising of 51,404 individuals from 69 countries. This dataset was collected for the International Collaboration on Social & Moral Psychology of COVID-19 project (ICSMP COVID-19). This social science survey invited participants around the world to complete a series of moral and psychological measures and public health attitudes about COVID-19 during an early phase of the COVID-19 pandemic (between April and June 2020). The survey included seven broad categories of questions: COVID-19 beliefs and compliance behaviours; identity and social attitudes; ideology; health and well-being; moral beliefs and motivation; personality traits; and demographic variables. We report both raw and cleaned data, along with all survey materials, data visualisations, and psychometric evaluations of key variables.
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| 2. |
- Van Bavel, Jay J., et al.
(författare)
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National identity predicts public health support during a global pandemic
- 2022
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Ingår i: Nature Communications. - : Nature Portfolio. - 2041-1723. ; 13:1
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Tidskriftsartikel (refereegranskat)abstract
- Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported greater engagement in public health behaviours and support for public health policies in the context of the pandemic. Changing collective behaviour and supporting non-pharmaceutical interventions is an important component in mitigating virus transmission during a pandemic. In a large international collaboration (Study 1, N = 49,968 across 67 countries), we investigated self-reported factors associated with public health behaviours (e.g., spatial distancing and stricter hygiene) and endorsed public policy interventions (e.g., closing bars and restaurants) during the early stage of the COVID-19 pandemic (April-May 2020). Respondents who reported identifying more strongly with their nation consistently reported greater engagement in public health behaviours and support for public health policies. Results were similar for representative and non-representative national samples. Study 2 (N = 42 countries) conceptually replicated the central finding using aggregate indices of national identity (obtained using the World Values Survey) and a measure of actual behaviour change during the pandemic (obtained from Google mobility reports). Higher levels of national identification prior to the pandemic predicted lower mobility during the early stage of the pandemic (r = -0.40). We discuss the potential implications of links between national identity, leadership, and public health for managing COVID-19 and future pandemics.
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| 3. |
- Dziewanowska, Julia, et al.
(författare)
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Nanocrystallization as a tool for controlling in vitro dissolution of borophosphate glass
- 2023
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Ingår i: Ceramics International. - : Elsevier. - 0272-8842 .- 1873-3956. ; 49:16, s. 27382-27390
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Tidskriftsartikel (refereegranskat)abstract
- The controlled nanocrystallization of sodium-calcium-borophosphate glass (Na16.6Ca5.1B10.5Al0.8P10.5 O56.5 in at %) was conducted to investigate its influence on in vitro dissolution. Three temperatures (570 degrees C, 590 degrees C, and 610 degrees C) were selected based on thermal analysis and investigation of the morphology, structure, and in vitro dissolution of glass and glass-ceramics was conducted. The results of X-ray diffraction confirmed the presence of calcium phosphates nanocrystallites in glass-ceramics, with their contents increasing proportionally to the crystallization temperature. Infrared spectroscopy showed the presence of phosphate and borate network units, along with phosphates in a crystalline form. It was found that the target glass shows the highest mass loss in comparison to the glass-ceramics. Controlled nanocrystallization slowed down the dissolution of the materials (>10%), but did not adversely affect the deposition of hydroxyapatite layer. The presence of calcium phosphate nanocrystallites favors the process of B3+ release. The nanocrystallization of borophosphate glasses is a perspective tool for controlling the rate of dissolution of bioactive materials and enhancing their ability to de-posit hydroxyapatite on their surface.
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| 4. |
- Koczkowska, Magdalena, et al.
(författare)
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Personalized health risk assessment based on single-cell RNA sequencing analysis of a male with 45, X/48, XYYY karyotype
- 2022
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Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 12:1
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Tidskriftsartikel (refereegranskat)abstract
- Numeric sex chromosome abnormalities are commonly associated with an increased cancer risk. Here, we report a 14-year-old boy with a rare mosaic 45, X/48, XYYY karyotype presenting with subtle dysmorphic features and relative height deficiency, requiring growth hormone therapy. As only 12 postnatal cases have been described so far with very limited follow-up data, to assess the proband's long-term prognosis, including cancer risk, we performed high-throughput single-cell RNA sequencing (scRNA-seq) analysis. Although comprehensive cytogenetic analysis showed seemingly near perfect balance between 45, X and 48, XYYY cell populations, scRNA-seq revealed widespread differences in genotype distribution among immune cell fractions, specifically in monocytes, B- and T-cells. These results were confirmed at DNA level by digital-droplet PCR on flow-sorted immune cell types. Furthermore, deregulation of predominantly autosomal genes was observed, including TCL1A overexpression in 45, X B-lymphocytes and other known genes associated with hematological malignancies. Together with the standard hematological results, showing increased fractions of monocytes and CD4+/CD8+T lymphocytes ratio, long-term personalized hemato-oncological surveillance was recommended in the reported patient.
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| 5. |
- Wojcik, Natalia Anna, et al.
(författare)
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Effect of crystallinity on structural, thermal, and in vitro dissolution properties of Na2O-CaO-Nb2O5/MgO-P2O5 glass-ceramics
- 2023
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Ingår i: Journal of the European Ceramic Society. - : Elsevier. - 0955-2219 .- 1873-619X. ; 43:5, s. 2234-2244
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Tidskriftsartikel (refereegranskat)abstract
- The impact of the crystallinity on structural, thermal, and in vitro dissolution properties were examined for Na2O-CaO-Nb2O5/MgO-P2O5 glasses/glass-ceramics. Glass-ceramics were synthesized via a spontaneous crystallization process. The Nb content in the materials increased with melting temperature, furthermore, the crystallinity is proportional to the Nb content. The presence of crystalline niobates and phosphates is confirmed by FTIR analysis which is consistent with XRD. The FTIR results indicate that the phosphate network is built of different proportions of Q2, Q1, and Q0 units, depending on the amount and type of crystalline phase. Most of the samples show an improvement in thermal stability. The in vitro dissolution test showed that the highest mass loss for most of the samples occurred during the first 6 days of immersion in the PBS solution. The presence of small phosphate crystals favors the deposition of hydroxyapatite on samples' surfaces while the larger niobate crystals dissolve more readily.
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