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- Bernal, Ximena E., et al.
(författare)
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Empowering Latina scientists
- 2019
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 363:6429, s. 825-826
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Jansson Mörk, Marie, et al.
(författare)
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Validation of a national disease recording system for dairy cattle against veterinary practice records
- 2010
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Ingår i: Preventive Veterinary Medicine. - : Elsevier BV. - 0167-5877 .- 1873-1716. ; 93, s. 183-192
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Tidskriftsartikel (refereegranskat)abstract
- In Sweden, morbidity in dairy cattle is monitored through a national disease recording system. This system gives valuable information for research as well as advisory work and genetic evaluation. Our main objective was to evaluate the completeness in the disease recording system.Farm copies of veterinary records (n = 851) from 112 herds, from March 2003 to April 2004, were compared with the information registered in the recording system. The evaluation of completeness was performed at two stages: (i) in the raw data transferred from the Swedish Board of Agriculture (SBA) to the Swedish Dairy Association (for records, cases and diagnostic events) and (ii) in the dairy disease database (DDD) at the Swedish Dairy Association (for diagnostic events). The evaluation was stratified by record type: manual and computerized records from state-employed veterinarians and private veterinarians, respectively.The completeness was high both for records (95-100%) and cases (90-99%) except manual records from private veterinarians (76% for records and 74% for cases). The overall completeness for diagnostic events was 75% in the DDD, with significant differences between record types. For all record types other than manual records from private veterinarians, the majority of diagnostic events lost disappeared after registration in the raw data from the SBA. The reasons for loss found suggest that there is potential for improvement.A multilevel logistic regression analysis showed that the completeness of diagnostic events in the DDD depended on region, diagnosis and veterinary employment. The random effect of veterinarian accounted for 35% of the modeled variation.Future studies are needed to assess how the differential misclassification affect estimates based on the data, and how to account for it. (C) 2009 Elsevier B.V. All rights reserved.
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| 6. |
- Köhler, Per, et al.
(författare)
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Influence of probe flexibility and gelatin embedding on neuronal density and glial responses to brain implants.
- 2015
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Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 10:3
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Tidskriftsartikel (refereegranskat)abstract
- To develop long-term high quality communication between brain and computer, a key issue is how to reduce the adverse foreign body responses. Here, the impact of probe flexibility and gelatine embedding on long-term (6w) tissue responses, was analyzed. Probes of same polymer material, size and shape, flexible mainly in one direction, were implanted in rat cerebral cortex (nimplants = 3 x 8) in two orientations with respect to the major movement direction of the brain relative to the skull: parallel to (flex mode) or transverse to (rigid mode). Flex mode implants were either embedded in gelatin or non-embedded. Neurons, activated microglia and astrocytes were visualized using immunohistochemistry. The astrocytic reactivity, but not microglial response, was significantly lower to probes implanted in flex mode as compared to rigid mode. The microglial response, but not astrocytic reactivity, was significantly smaller to gelatin embedded probes (flex mode) than non-embedded. Interestingly, the neuronal density was preserved in the inner zone surrounding gelatin embedded probes. This contrasts to the common reports of reduced neuronal density close to implanted probes. In conclusion, sheer stress appears to be an important factor for astrocytic reactivity to implanted probes. Moreover, gelatin embedding can improve the neuronal density and reduce the microglial response close to the probe.
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