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| 2. |
- Geborek, Pierre, et al.
(författare)
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Mononuclear cells recovered from inflammatory synovial membrane using fine-needle biopsy
- 1988
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Ingår i: Rheumatology International. - 1437-160X. ; 8:3, s. 101-105
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Tidskriftsartikel (refereegranskat)abstract
- A simple technique for fine-needle aspiration biopsy from the synovial membrane of arthritis knee joints preceded by lavage of the joint cavity is described. The procedure was atraumatic, well accepted, and could be performed on outpatients. Cells originating from the synovial membrane were obtained in 12 of 17 knees using a 1.2-mm cannula. The yield was 6.0 x 10(3) to 135 x 10(3) mononuclear cells. The cell populations could be expanded by stimulation with antigen and mitogen. The described fine-needle biopsy technique is of value when repeated sampling of synovial membrane cell populations is desired.
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| 3. |
- Scheja, Agneta, et al.
(författare)
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Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma)
- 2001
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Ingår i: Arthritis Research & Therapy. - : Springer Science and Business Media LLC. - 1465-9913 .- 1465-9905. ; 3:3, s. 178-182
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Tidskriftsartikel (refereegranskat)abstract
- In 44 consecutive patients with systemic sclerosis (SSc), plasma concentrations of von Willebrand factor (vWf) were higher than those of the vWf propeptide, but the propeptide showed less variability within patient subgroups. Higher values of the propeptide were observed in patients with early pulmonary involvement. A closer correlation of the propeptide than of vWf to biochemical markers of activity was also evident. Our results suggest that the propeptide, despite a shorter circulating half-time and lower plasma concentrations than vWf, is more useful in the assessment of disease activity in SSc.
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| 4. |
- Wollheim, Frank, et al.
(författare)
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Genetics and susceptibility to RA - More than HLA
- 2003
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Ingår i: Scandinavian Journal of Rheumatology. - : Informa UK Limited. - 1502-7732 .- 0300-9742. ; 32:3, s. 196-196
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Abignano, Giuseppina, et al.
(författare)
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Collagenous colitis in systemic sclerosis: an overlooked and treatable complication.
- 2014
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Ingår i: Journal of Clinical Rheumatology. - 1536-7355. ; 20:5, s. 278-282
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Tidskriftsartikel (refereegranskat)abstract
- Collagenous colitis (CC) is an inflammatory bowel condition of unknown etiology. Systemic sclerosis (SSc) has been associated with CC in a few cases, but it is not clear whether CC could be considered an unusual manifestation of SSc or an independent condition. Here we present a case of SSc-associated CC and compare routine histology and immunofluorescence studies for allograft inflammatory factor 1 and caveolin 1 expression with other cases of CC and healthy controls. All CC biopsies showed characteristic sublaminal collagen accumulation and a decrease of caveolin 1 expression, this latter finding consistent with and common in any fibrotic reaction. In contrast, the expression of allograft inflammatory factor 1 was increased only in the SSc-CC specimen, suggesting a distinct pathogenesis. A literature review revealed 6 previously reported cases of SSc-CC with common clinical features. These observations suggest that CC should be suspected as a rare gastrointestinal complication of SSc and that clinicians should be aware of the possibility in SSc patients developing watery diarrhea.
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| 6. |
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| 7. |
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| 8. |
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| 9. |
- Chard, Jiri, et al.
(författare)
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Osteoarthritis
- 2002
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Ingår i: Clinical evidence. - 1462-3846. ; 14:5, s. 571-572
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Tidskriftsartikel (refereegranskat)
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| 10. |
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