| 1. |
- Dainotti, Maria Giovanna, et al.
(författare)
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Predicting the Redshift of γ-Ray-loud AGNs Using Supervised Machine Learning
- 2021
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 920:2
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Tidskriftsartikel (refereegranskat)abstract
- Active galactic nuclei (AGNs) are very powerful galaxies characterized by extremely bright emissions coming from their central massive black holes. Knowing the redshifts of AGNs provides us with an opportunity to determine their distance to investigate important astrophysical problems, such as the evolution of the early stars and their formation, along with the structure of early galaxies. The redshift determination is challenging because it requires detailed follow-up of multiwavelength observations, often involving various astronomical facilities. Here we employ machine-learning algorithms to estimate redshifts from the observed γ-ray properties and photometric data of γ-ray-loud AGNs from the Fourth Fermi-LAT Catalog. The prediction is obtained with the Superlearner algorithm using a LASSO-selected set of predictors. We obtain a tight correlation, with a Pearson correlation coefficient of 71.3% between the inferred and observed redshifts and an average Δz norm = 11.6 10-4. We stress that, notwithstanding the small sample of γ-ray-loud AGNs, we obtain a reliable predictive model using Superlearner, which is an ensemble of several machine-learning models.
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| 3. |
- Rajab, Amr, et al.
(författare)
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Ten-color 15-antibody flow cytometry panel for immunophenotyping of lymphocyte population
- 2017
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Ingår i: International Journal of Laboratory Hematology. - : Wiley. - 1751-5521. ; 39, s. 76-85
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Forskningsöversikt (refereegranskat)abstract
- We have developed a lymphoproliferative disorder screening tube (LPD-ST) with the aim to provide comprehensive immunophenotyping of lymphocyte subsets with minimal need for additional testing. The LPD-ST consists of CD4/kappa FITC, CD8/lambda PE, CD3/CD14ECD, CD38PC5.5, CD20/CD56PC7, CD10APC, CD19APC-A700, CD5APC-A750, CD57/CD23PB and CD45KO. The LPD-ST was validated against previously used lymphocyte subset panels in Canada (n=60) and in Sweden (n=43) and against the OneFlow™ LST (n=60). The LPD-ST panel was then implemented in clinical practice using dried monoclonal antibody reagents (Duraclone®) on 649 patient samples in Sweden. In 204 of 649 samples (31%), a monotypic B-cell population was found. Of these cases, a final diagnosis could be rendered in 106 cases (52%), and in the remainder, additional B-cell immunophenotyping was performed. In 20 (3%) samples, an aberrant T-cell population was confirmed by additional testing. Of 425 samples diagnosed as normal/reactive lymphoid tissue, 50 (12%) required additional immunophenotyping, mostly due to an abnormal CD4/CD8 ratio. The LPD-ST tube significantly minimizes the need for additional testing, improves the turn-around time, and reduces the cost of LPD immunophenotyping. It is also suitable for investigating paucicellular samples such as cerebrospinal fluid or fine needle aspirates.
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