| 1. |
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- 2019
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Han, Yang, et al.
(författare)
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X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer
- 2012
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Ingår i: Radiation Oncology. - : BioMed Central. - 1748-717X. ; 7:183
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundHistone deacetylase (HDAC) plays an important role in the deacetylation of histone, which can alter gene expression patterns and affect cell behavior associated with malignant transformation. The aims of this study were to investigate the relationships between HDAC1, HDAC2, clinicopathologic characteristics, patient prognosis and apoptosis, to clarify the mechanism of upregulation of the Axis inhibitor Axin (an important regulator of the Wnt pathway) by X-radiation and to elucidate the effect of siRNA on radiation therapy of non-small cell lung cancer (NSCLC).MethodsHDAC1 and HDAC2 expression levels were measured by immunohistochemistry and reverse transcription PCR. Apoptosis was determined by terminal deoxynucleotidyl transferase-mediated dUTP-nick end labeling and fluorescence activated cell sorting. BE1 cells expressing Axin were exposed to 2 Gy of X-radiation.ResultsExpression of HDAC1 and that of HDAC2 were correlated, and significantly higher in NSCLC tissues than in normal lung tissues (P < 0.05). HDAC1 and HDAC2 expression was correlated with pTNM stage and negatively correlated with differentiation of NSCLC and apoptotic index (P < 0.05). The prognosis of patients with low expression of HDAC1 and HDAC2 was better than that of those with high expression. X-radiation and siRNA inhibited HDAC1 and HDAC2 expression in NSCLC cells and Axin levels were significantly higher in BE1 cells.ConclusionsX-radiation and siRNA inhibit expression of HDAC1 and HDAC2, weaken the inhibitory effect of HDAC on Axin, upregulate Axin expression and induce apoptosis of lung cancer cells. Inhibition of HDAC1 and HDAC2 is a means of enhancing the radiosensitivity of NSCLC.
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| 3. |
- Liu, Wei, et al.
(författare)
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Coherent dynamics of multi-spin V-B(-) center in hexagonal boron nitride
- 2022
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Ingår i: Nature Communications. - : Nature Portfolio. - 2041-1723. ; 13:1
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Tidskriftsartikel (refereegranskat)abstract
- Hexagonal boron nitride (hBN) has recently been demonstrated to contain optically polarized and detected electron spins that can be utilized for implementing qubits and quantum sensors in nanolayered-devices. Understanding the coherent dynamics ofmicrowave driven spins in hBN is of crucial importance for advancing these emerging new technologies. Here, we demonstrate and study the Rabi oscillation and related phenomena of a negatively charged boron vacancy (V-B(-)) spin ensemble in hBN. We report on different dynamics of the V-B(-) spins at weak and strong magnetic fields. In the former case the defect behaves like a single electron spin system, while in the latter case it behaves like a multi-spin system exhibiting multiple-frequency dynamical oscillation as beat in the Ramsey fringes. We also carry out theoretical simulations for the spin dynamics of V-B(-) and reveal that the nuclear spins can be driven via the strong electron nuclear coupling existing in V-B(-) center, which can be modulated by the magnetic field and microwave field.
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| 4. |
- Allison, Robert S., et al.
(författare)
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Perspectives on the definition of visually lossless quality for mobile and large format displays
- 2018
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Ingår i: Journal of Electronic Imaging (JEI). - 1017-9909 .- 1560-229X. ; 27:5, s. 1-23
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Tidskriftsartikel (refereegranskat)abstract
- Advances in imaging and display engineering have given rise to new and improved image and videoapplications that aim to maximize visual quality under given resource constraints (e.g., power, bandwidth).Because the human visual system is an imperfect sensor, the images/videos can be represented in a mathematicallylossy fashion but with enough fidelity that the losses are visually imperceptible—commonly termed“visually lossless.” Although a great deal of research has focused on gaining a better understanding ofthe limits of human vision when viewing natural images/video, a universally or even largely accepted definitionof visually lossless remains elusive. Differences in testing methodologies, research objectives, and targetapplications have led to multiple ad-hoc definitions that are often difficult to compare to or otherwise employ inother settings. We present a compendium of technical experiments relating to both vision science and visualquality testing that together explore the research and business perspectives of visually lossless image quality,as well as review recent scientific advances. Together, the studies presented in this paper suggest that a singledefinition of visually lossless quality might not be appropriate; rather, a better goal would be to establish varyinglevels of visually lossless quality that can be quantified in terms of the testing paradigm.
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| 5. |
- Chen, Geng, et al.
(författare)
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Experimental Test of the State Estimation-Reversal Tradeoff Relation in General Quantum Measurements
- 2014
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Ingår i: Physical Review X. - 2160-3308. ; 4:5, s. 021043-
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Tidskriftsartikel (refereegranskat)abstract
- When a measurement has limited strength, only partial information, regarding the initial state, is extracted, and, correspondingly, there is a probability to reverse its effect on the system and retrieve the original state. Recently, a clear and direct quantitative description of this complementary relationship, in terms of a tradeoff relation, was developed by Y. K. Cheong and S. W. Lee. [Phys. Rev. Lett. 109, 150402 (2012)]. Here, this tradeoff relation is experimentally verified using polarization-encoded single photons from a quantum dot. Measurement operators representing a complete range, from not affecting the system to a projection to a single polarization state, are realized. In addition, for each measurement operator, an optimal reversal operator is also implemented. The upper bound of the tradeoff relation is mapped to experimental parameters representing the measurement strength. Our results complement the theoretical work and provide a hands-on characterization of general quantum measurements.
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| 6. |
- Chen, Jun-Tong, et al.
(författare)
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Corydalis sunhangii (Papaveraceae) : A new species from Xizang, China, based on plastome and morphological data
- 2024
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Ingår i: Ecology and Evolution. - : John Wiley & Sons. - 2045-7758. ; 14:4
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Tidskriftsartikel (refereegranskat)abstract
- A new species of Papaveraceae, Corydalis sunhangii, in the section Trachycarpae, is described and illustrated from Nyingchi City, Xizang, China. The new species has some resemblance to Corydalis kingdonis, but differs by radical leaves prominent, usually several, blade tripinnate (vs. insignificant, few, blade bi- to triternate); cauline leaf usually one, much smaller than radical leaves, usually situated in lower half of stem (vs. usually two, larger than radical leaves, concentrated in upper third of stem); racemes densely 13-35-flowered (vs. rather lax, 4-11-flowered); claw of lower petal shallowly saccate (vs. very prominently and deeply saccate); capsule oblong, with raised lines of dense papillae (vs. broadly obovoid, smooth). Phylogenetic analysis, based on 68 protein-coding plastid genes of 49 samples, shows that C. sunhangii is not closely related to any hitherto described species, which is consistent with our morphological analysis.
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| 7. |
- Depalo, Francesco, et al.
(författare)
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Effects of dynamic axial stiffness of elastic moorings for a wave energy converter
- 2022
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Ingår i: Ocean Engineering. - : Elsevier BV. - 0029-8018. ; 251
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Tidskriftsartikel (refereegranskat)abstract
- This work studies the effects of the dynamic axial stiffness of elastic moorings on the dynamic behaviour of a point absorber wave energy converter. Following two mooring analysis procedures, coupled dynamic analysis of a taut-moored WEC with three legs is performed using the FEM program DeepC in three irregular wave conditions. Two synthetic fibre rope materials are investigated, i.e. a normally stiff polyester and a wire-lay 3-strand nylon rope. The results of WEC motions and mooring tensions obtained from a quasi-static stiffness model and the dynamic stiffness model are compared and discussed. The former analysis applies the non-linear stiffness working curves of the ropes in the simulations, while the latter utilizes the dynamic stiffness expression with an iterative process following a practical mooring analysis procedure. For the nylon rope, the influence of the load amplitude on the dynamic stiffness and the WEC response is presented and analysed. It was found that the quasi-static stiffness model tends to underestimate the maximum mooring tensions, leading to 30%–40% lower results compared to the one accounting for the dynamic stiffness effects. For the studied WEC system, the nylon rope shows advantages over polyester, because of the lower mooring tensions and higher WEC motions.
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| 8. |
- Dong, Jiankai, et al.
(författare)
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An experimental study on a novel radiant-convective heating system based on air source heat pump
- 2018
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Ingår i: Energy and Buildings. - : Elsevier BV. - 0378-7788 .- 1872-6178. ; 158, s. 812-821
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Tidskriftsartikel (refereegranskat)abstract
- Air source heat pump (ASHP) has been widely applied to many parts of the world due to its simple structure and low initial cost. To save energy consumed for spacing heating and enhance the indoor thermal environment, improving the performances of ASHP has become one of the research focus in the relevant field. Currently, the most conventional heating terminal of ASHP system for spacing heating is finned tube heat exchanger coupled with air fan, which may cause strong draught sensation and dry eye problem and make users feel uncomfortable during convective heating. On the other hand, radiant heating is attracting more and more attention due to its comfortable indoor thermal environment. In this paper, a novel radiant-convective heating terminal was presented and coupled into an ASHP system. Both the operating characteristics and heating performances of the novel system were experimentally investigated. The experimental results showed that the novel system took about 28 min to enter a steady operating stage, during which the radiant panel surface temperature and outlet air temperature for the novel heating terminal, and COP of the novel system were 40.9 degrees C, 32.1 degrees C, and 3.11, respectively, under a standard heating condition. In addition, all parameters mentioned above saw a linear increase when the outdoor air temperature increased from -4.0 to 10.0 degrees C, and their respective rising rates were 0.41 degrees C, 0.28 degrees C and 0.04 per increased outdoor air temperature. Furthermore, the experimental results also demonstrated that adjusting the indoor air flow rate could effectively allocate the amount of heat generated by different heat transfer modes, which may have significant effects on the indoor thermal environment.
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| 9. |
- Fayazi, Seyedeh Shaghayegh, et al.
(författare)
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Microwave imaging of near-field object using ultra-wideband synthetic aperture radar algorithm
- 2012
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Ingår i: 2012 IEEE ANTENNAS AND PROPAGATION SOCIETY INTERNATIONAL SYMPOSIUM (APSURSI). - 1522-3965. - 9781467304627
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Konferensbidrag (refereegranskat)abstract
- A simple procedure that suppresses artefact from ultra-wideband (UWB) synthetic aperture radar (SAR) images is proposed and verified using experimental data. The proposed imaging solution is useful for imaging small objects located in the near-field region with less ambiguity.
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| 10. |
- Fayazi, Seyedeh Shaghayegh, et al.
(författare)
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UWB SAR Imaging of Near-Field Object for Industrial Process Applications
- 2013
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Ingår i: 7th European Conference on Antennas and Propagation, EuCAP 2013, Gothenburg, Sweden, 8-12 April 2013. - 2164-3342. - 9781467321877 ; , s. 2245-2248
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Konferensbidrag (refereegranskat)abstract
- Ultra wideband technology becomes more widely used for near-field object detection. We present an aperture synthetic radar (SAR) system using ultra-wideband (UWB) signals for such applications. One of the problems with UWB time-domain SAR imaging algorithm is the artefact originated from scattered field of adjacent objects. In this paper an algorithm based on the Range Point Migration (RPM) method is used to alleviate this problem. This method estimates a possibility distribution of the optimal Direction of Arrival (DOA) of the scattered field from objects. A weighting factor based on this possibility is used to suppress the effect of artifact scattered fields. The results in the paper show that the UWB SAR accompanied with RPM can produce an image of an object with a significant suppression of undesired artifact from scattered field of adjacent objects.
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