| 1. |
|
|
| 2. |
- Jin, Yanghao, et al.
(författare)
-
Carbon and H-2 recoveries from plastic waste by using a metal-free porous biocarbon catalyst
- 2023
-
Ingår i: Journal of Cleaner Production. - : Elsevier BV. - 0959-6526 .- 1879-1786. ; 404
-
Tidskriftsartikel (refereegranskat)abstract
- Carbon and H2 recoveries from plastic waste enable high value-added utilizations of plastic waste while mini-mizing its GHG emissions. The objective of this study is to explore the use of a metal-free biocarbon catalyst for waste plastic pyrolysis and in-line catalytic cracking to produce H2-rich gases and carbon. The results show that the biocarbon catalyst exhibits a good catalytic effect and stability for various plastic wastes. Increasing the C/P ratio from 0 to 2, induce an increase in the conversion rate of C and H in plastics to carbon and H2 from 57.1% to 68.7%, and from 22.7% to 53.5%, respectively. Furthermore, a carbon yield as high as 580.6 mg/gplastic and an H2 yield as high as 68.6 mg/gplastic can be obtained. The hierarchical porous structure with tortuous channels of biocarbon extends the residence time of pyrolysis volatiles in the high-temperature catalytic region and thereby significantly promotes cracking reactions.
|
|
| 3. |
- Satizabal, Claudia L., et al.
(författare)
-
Genetic architecture of subcortical brain structures in 38,851 individuals
- 2019
-
Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 51:11, s. 1624-
-
Tidskriftsartikel (refereegranskat)abstract
- Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus, using genome-wide association analyses in almost 40,000 individuals from CHARGE, ENIGMA and UK Biobank. We show that variability in subcortical volumes is heritable, and identify 48 significantly associated loci (40 novel at the time of analysis). Annotation of these loci by utilizing gene expression, methylation and neuropathological data identified 199 genes putatively implicated in neurodevelopment, synaptic signaling, axonal transport, apoptosis, inflammation/infection and susceptibility to neurological disorders. This set of genes is significantly enriched for Drosophila orthologs associated with neurodevelopmental phenotypes, suggesting evolutionarily conserved mechanisms. Our findings uncover novel biology and potential drug targets underlying brain development and disease.
|
|
| 4. |
- Shen, Yang-mei, et al.
(författare)
-
Novel gene hBiot2 is an independent prognostic factor in colorectal cancer patients
- 2012
-
Ingår i: Oncology Reports. - : Spandidos Publications. - 1021-335X .- 1791-2431. ; 27:2, s. 376-382
-
Tidskriftsartikel (refereegranskat)abstract
- The present study investigated the expression of the novel gene hBiot2 in colorectal cancer (CRC) and its relationships with clinicopathological variables in CRC patients. The expression of hBiot2 in 163 primary CRCs together with the corresponding normal mucosa, 36 liver metastases and 5 colon cancer cell lines was examined using real-time PCR. In situ hybridization (ISH) was performed to evaluate the localization of hBiot2 expression in CRC and normal mucosa. hBiot2 expression at the RNA level was localized in the nucleus of tumor cells and normal epithelial cells. The mean expression of hBiot2 in the CRCs (243.571 +/- 564.569) was higher compared to the normal mucosa (107.252 +/- 413.635, Pandlt;0.0001) and liver metastasis samples (42.002 +/- 40.809, P=0.0002). hBiot2 expression was increased from stages I + II to III (P=0.047), and no difference in the expression was found in stages III and IV (P=0.452). A high value of hBiot2 was associated with a poorer prognosis compared with a low value independently of gender, age, tumor site, stage and differentiation (P=0.007, RR 7.519, 95% Cl 1.729-32.704). Liver metastasis, smaller tumors, non-local recurrence and primary liver surgery alone were associated with a higher value of hBiot2 compared to larger tumors, local recurrence and repeated liver surgery (P=0.003, 0.044 and 0.026, respectively). An inverse relationship was found between hBiot2 expression and the metastatic potential of the colon cancer cell lines. Thus, increased expression of hBiot2 may be an early and interim event in the development of CRC. A higher expression of hBiot2 in primary CRC patients independently indicates a poorer prognosis.
|
|
| 5. |
- Yang, Chao-Tung, et al.
(författare)
-
Implementation of a real-time network traffic monitoring service with network functions virtualization
- 2019
-
Ingår i: Future generations computer systems. - : Elsevier. - 0167-739X .- 1872-7115. ; 93, s. 687-701
-
Tidskriftsartikel (refereegranskat)abstract
- The Network Functions Virtualization (NFV) extends the functionality provided by Software-Defined Networking (SDN). It is a virtualization technology that aims to replace the functionality provided by traditional networking hardware using software solutions. Thereby, enabling cheaper and efficient network deployment and management. The use of NFV and SDN is anticipated to enhance the performance of Infrastructure-as-a-Service (IaaS) clouds. However, due to the presence of a large number of network devices in IaaS clouds offering a plethora of networked services, there is need to develop a traffic monitoring system for the efficient network. This paper proposes and validates an extensible SDN and NFV-enabled network traffic monitoring system. Using extensive experiments, we show that the proposed system can closely match the performance of traditional networks at cheaper costs and by adding more flexibility to network management tasks.
|
|
| 6. |
- Cheng, Jie, et al.
(författare)
-
RE (La, Nd and Yb) doped CeO2 abrasive particles for chemical mechanical polishing of dielectric materials : Experimental and computational analysis
- 2020
-
Ingår i: Applied Surface Science. - : ELSEVIER. - 0169-4332 .- 1873-5584. ; 506
-
Tidskriftsartikel (refereegranskat)abstract
- Ce3+ in CeO2, rather than Ce4+, is believed to provide assistance to the breaking up of Si-O bond during chemical mechanical polishing (CMP) of silica. In the paper, lanthanide metals (La, Nd and Yb) doped CeO2 nanoparticles were synthesized by modified incipient impregnation method in order to improve the content of Ce3+ in CeO2 as polishing. X-ray photoelectron spectroscopy (XPS) experiments and density function theory (DFT) calculation demonstrate this approach could achieve surface doping of CeO2 nanoparticles, and facilitates the formation of oxygen vacancy and Ce3+ content. CMP experiments show that the polishing rate and the surface quality of silica wafer are obviously improved by using the doped CeO2 as abrasive particles. Especially for Nd/CeO2, content of Ce3+ increases from 0.146 to 0.235, the polishing rate of silica is accelerated by 29.6% in alkaline slurries, and a better surface quality (Sa = 9.6 angstrom) is obtained.
|
|
| 7. |
|
|
| 8. |
- Feng, Kailun, 1991-, et al.
(författare)
-
Embedding Ensemble Learning into Construction Optimisation : A Computational Reduction Approach
- 2020
-
Tidskriftsartikel (refereegranskat)abstract
- Simulation-based optimisation (SO), which combines simulation and optimisation technologies, is a popular approach for construction planning optimisation. However, in the framework of SO, the simulation is continuously invoked during the optimisation trajectory, which increases the computing loads to levels that are unrealistic to support the real-time construction decision. This study proposes ensemble learning embedded simulation optimisation (ESO) as an alternative approach for construction optimisation. The ensemble learning (EL) algorithm modifies the SO framework through establishing a connection between the simulation and optimisation technologies. This approach reduces the computing loads associated with the conventional SO framework by accurately learning from simulations and providing efficient fitness evaluations for optimisation. A large-scale project application shows that the proposed approach was able to reduce the computing loads of SO by approximately 90% yet still provide comparable optimisation quality. The proposed method is an alternative approach to SO that can be run on standard computing platforms and supports nearly real-time optimisation decisions.
|
|
| 9. |
- Feng, Kailun, 1991-, et al.
(författare)
-
Embedding ensemble learning into simulation-based optimisation : a learning-based optimisation approach for construction planning
- 2023
-
Ingår i: Engineering Construction and Architectural Management. - : Emerald Group Publishing Limited. - 0969-9988 .- 1365-232X. ; 30:1, s. 259-295
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose - Simulation-based optimisation (SO) is a popular optimisation approach for building and civil engineering construction planning. However, in the framework of SO, the simulation is continuously invoked during the optimisation trajectory, which increases the computational loads to levels unrealistic for timely construction decisions. Modification on the optimisation settings such as reducing searching ability is a popular method to address this challenge, but the quality measurement of the obtained optimal decisions, also termed as optimisation quality, is also reduced by this setting. Therefore, this study aims to develop an optimisation approach for construction planning that reduces the high computational loads of SO and provides reliable optimisation quality simultaneously.Design/methodology/approach - This study proposes the optimisation approach by modifying the SO framework through establishing an embedded connection between simulation and optimisation technologies. This approach reduces the computational loads and ensures the optimisation quality associated with the conventional SO approach by accurately learning the knowledge from construction simulations using embedded ensemble learning algorithms, which automatically provides efficient and reliable fitness evaluations for optimisation iterations.Findings - A large-scale project application shows that the proposed approach was able to reduce computational loads of SO by approximately 90%. Meanwhile, the proposed approach outperformed SO in terms of optimisation quality when the optimisation has limited searching ability.Originality/value - The core contribution of this research is to provide an innovative method that improves efficiency and ensures effectiveness, simultaneously, of the well-known SO approach in construction applications. The proposed method is an alternative approach to SO that can run on standard computing platforms and support nearly real-time construction on-site decision-making.
|
|
| 10. |
|
|
