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| 2. |
- An, Junghwa, et al.
(författare)
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Permanent Genetic Resources added to Molecular Ecology Resources Database 1 October 2009-30 November 2009
- 2010
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Ingår i: Molecular Ecology Resources. - : Wiley. - 1755-098X .- 1755-0998. ; 10:2, s. 404-408
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Tidskriftsartikel (refereegranskat)abstract
- This article documents the addition of 411 microsatellite marker loci and 15 pairs of Single Nucleotide Polymorphism (SNP) sequencing primers to the Molecular Ecology Resources Database. Loci were developed for the following species: Acanthopagrus schlegeli, Anopheles lesteri, Aspergillus clavatus, Aspergillus flavus, Aspergillus fumigatus, Aspergillus oryzae, Aspergillus terreus, Branchiostoma japonicum, Branchiostoma belcheri, Colias behrii, Coryphopterus personatus, Cynogolssus semilaevis, Cynoglossus semilaevis, Dendrobium officinale, Dendrobium officinale, Dysoxylum malabaricum, Metrioptera roeselii, Myrmeciza exsul, Ochotona thibetana, Neosartorya fischeri, Nothofagus pumilio, Onychodactylus fischeri, Phoenicopterus roseus, Salvia officinalis L., Scylla paramamosain, Silene latifo, Sula sula, and Vulpes vulpes. These loci were cross-tested on the following species: Aspergillus giganteus, Colias pelidne, Colias interior, Colias meadii, Colias eurytheme, Coryphopterus lipernes, Coryphopterus glaucofrenum, Coryphopterus eidolon, Gnatholepis thompsoni, Elacatinus evelynae, Dendrobium loddigesii Dendrobium devonianum, Dysoxylum binectariferum, Nothofagus antarctica, Nothofagus dombeyii, Nothofagus nervosa, Nothofagus obliqua, Sula nebouxii, and Sula variegata. This article also documents the addition of 39 sequencing primer pairs and 15 allele specific primers or probes for Paralithodes camtschaticus.
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| 3. |
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- 2019
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Tidskriftsartikel (refereegranskat)
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| 4. |
- Bi, Hui, et al.
(författare)
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Investigation on the joint travel behavior in bike sharing systems during the COVID-19 pandemic: Insights from New York City
- 2024
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Ingår i: Journal of Transport Geography. - 0966-6923. ; 117
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Tidskriftsartikel (refereegranskat)abstract
- As the COVID-19 pandemic worsened, many people saw bikes as one of the safest means of transportation in the hard-hit cities. All the bike sharing utilization patterns during the pandemic are worthy of careful attention. However, there is still a lack of comprehensive understanding of niche but notable cycling behaviors, such as multi-person round trip (MPRT), defined as two or more cyclists intentionally riding together then returning bikes to the original docking station. This study extends the relevant literature by firstly proposing a MPRT identification framework based on individual bike sharing trip records, with consideration of interpersonal relationships between co-travelers, as well as the specificity of round trips against one-way trips. Taking New York City as a case study, this study examines the changes over space and time of MPRT frequencies from 2019 (i.e. pre-pandemic period) to 2020 (i.e. pandemic period), and the reasons for it. Notably, special consideration of the aforementioned analysis is paid to the influence of the real-time situation of COVID-19 in terms of cases, deaths, hospitalizations, and tests. Results reveal that (1) the MPRT frequencies obey a long tail distribution, both prior to and during the COVID-19 outbreak; (2) the group size, temporal patterns and co-traveler community are profoundly affected by the COVID-19 outbreak; (3) four indicators related to COVID-19 show different influences on co-travelers over time; (4) bike sharing availability and personal economic situation are closely related with MPRT frequencies. These findings can help develop more targeted strategies for improving the operation of a bike sharing system to meet the possible diversified demands of cyclists during the future pandemics.
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| 5. |
- Deng, Min, et al.
(författare)
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Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis
- 2013
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Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 45:6, s. 697-
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Tidskriftsartikel (refereegranskat)abstract
- To identify susceptibility genes for amyotrophic lateral sclerosis (ALS), we conducted a genome-wide association study (GWAS) in 506 individuals with sporadic ALS and 1,859 controls of Han Chinese ancestry. Ninety top SNPs suggested by the current GWAS and 6 SNPs identified by previous GWAS were analyzed in an independent cohort of 706 individuals with ALS and 1,777 controls of Han Chinese ancestry. We discovered two new susceptibility loci for ALS at 1q32 (CAMK1G, rs6703183, P-combined = 2.92 x 10(-8), odds ratio (OR) = 1.31) and 22p11 (CABIN1 and SUSD2, rs8141797, P-combined = 2.35 x 10(-9), OR = 1.52). These two loci explain 12.48% of the overall variance in disease risk in the Han Chinese population. We found no association evidence for the previously reported loci in the Han Chinese population, suggesting genetic heterogeneity of disease susceptibility for ALS between ancestry groups. Our study identifies two new susceptibility loci and suggests new pathogenic mechanisms of ALS.
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| 6. |
- Huang, Shirong, et al.
(författare)
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Infrared Emissivity Measurement for Vertically Aligned Multiwall Carbon Nanotubes (CNTs) Based Heat Spreader Applied in High Power Electronics Packaging
- 2016
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Ingår i: 6th Electronic System-integration Technology Conference (ESTC 2016). - 9781509014026 ; , s. Article no 7764696-
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Konferensbidrag (refereegranskat)abstract
- Vertically-aligned multiwall carbon nanotubes were deposited on silicon substrate by low pressure chemical vapor deposition (LPCVD), which can be utilized as heat spreaders in high power electronic packaging due to their remarkable thermal conductivity. The infrared emissivity of the vertically aligned multiwall carbon nanotubes was then characterized based on the FLIR SC600 infrared imaging system. The average infrared emissivity of the multiwall carbon nanotubes sample was about 0.92, which agrees well with experimental results reported before. Scanning electron microscopy (SEM) images of the multiwall carbon nanotubes were further analyzed to explain its high emissivity, and the reason can be attributed to the homogeneous sparseness and aligned structure of the vertically aligned multiwall carbon nanotubes
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| 7. |
- Klionsky, Daniel J., et al.
(författare)
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Guidelines for the use and interpretation of assays for monitoring autophagy
- 2012
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Ingår i: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 8:4, s. 445-544
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Forskningsöversikt (refereegranskat)abstract
- In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field.
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| 8. |
- Xu, Hui, et al.
(författare)
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Impact of Pore Structure on Two-Electron Oxygen Reduction Reaction in Nitrogen-Doped Carbon Materials : Rotating Ring-Disk Electrode vs. Flow Cell
- 2022
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Ingår i: ChemSusChem. - : Wiley. - 1864-5631 .- 1864-564X. ; 15:5
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Tidskriftsartikel (refereegranskat)abstract
- The impact of pore structure on the two-electron oxygen reduction reaction (ORR) in nitrogen-doped carbon materials is currently under debate, and previous studies are mainly limited to the rotating ring-disk electrode (RRDE) rather than the practical flow cell (FC) system. In this study, assisted by a group of reliable pore models, the impact of two pore structure parameters, that is, Brunauer–Emmett–Teller surface area (SBET) and micropore surface fraction (fmicro), on ORR activity and selectivity are investigated in both RRDE and FC. The ORR mass activity correlates positively to the SBET in the RRDE and FC because a higher SBET can host more active sites. The H2O2 selectivity is independent of fmicro in the RRDE but correlates negatively to fmicro in the FC. The inconsistency results from different states of the electrode in the RRDE and the FC. These insights will guide the design of carbon materials for H2O2 synthesis.
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| 9. |
- Ye, Hui, et al.
(författare)
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Preventing Aging of Electrically Conductive Adhesives on Metal Substrate Using Graphene-Based Barrier
- 2016
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Ingår i: China Semiconductor Technology International Conference 2016, CSTIC 2016. - 9781467388047
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Konferensbidrag (refereegranskat)abstract
- Electrically conductive adhesives (ECAs) seem to be a promising substitute to traditional metal-based solders, because of them being environmentally friendly materials requiring much lower processing temperatures, and offering a much finer pitch. However, a critical problem related to the use of ECAs is that the contact resistance to the metal pad tends to increase significantly during aging tests due to galvanic corrosion, particularly in 85oC/85% relative humidity (RH) atmospheres. In this respect the reported impermeability of graphene, a property prohibiting most molecules including water vapor from penetrating the film, has made graphene a major candidate as an anti-corrosion barrier material. The use of graphene as an anti-corrosion barrier material on steel and other metals has already been reported in literature. In this paper, the use of graphene-based barriers[12] between the ECA and the copper pads on a printed circuit board for alleviating the galvanic corrosion problem is reported. A PCB test board was designed for monitoring the effects of introducing the graphene-based barrier on the contact resistance between ECA and copper while exposing the board to a 500 hour aging test in 85℃/85% RH. For samples without graphene-based barriers it was found that the contact resistance increased rapidly during the first 200 hours of the aging test, while the contact resistance for samples with the graphene-based barriers remained stable. For these samples with graphene-based barriers, the contact resistance showed a much smaller decay during the aging test than for those samples without graphene-based barriers. These findings indicate that graphene-based barriers could be a solution for improving the reliability of electrically conductive adhesives, especially in harsh 85oC/85% RH environment conditions.
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| 10. |
- Bi, Hui, et al.
(författare)
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Bicycle safety outside the crosswalks: Investigating cyclists' risky street-crossing behavior and its relationship with built environment
- 2023
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Ingår i: Journal of Transport Geography. - : Elsevier BV. - 0966-6923. ; 108
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Tidskriftsartikel (refereegranskat)abstract
- Most bicycle accidents are inextricably bound up with risky riding behaviors, which crossing the street illegally at unprotected mid-block locations is nothing to sneeze at. Compared with cyclists crossing the street at the crosswalk or intersections, there is a huge risk of accidents when they ignore or disobey road rules and across recklessly. Yet, the misbehavior of cyclists is an under-explored area in cyclist research due to the limited availability of detailed cycling data. This study creatively develops a GPS-based detection framework to capture risky street-crossing actions for the cyclists from large-scale bike sharing trajectory data. A data-driven modeling approach, based on structural topic modeling (STM), is developed to reveal the complexity and regularity of cyclists' habitual risky crossing behavior. Since objective built environment is one of the key factors associated with cycling, another goal of this paper is to apply a gradient boosting decision tree (GBDT) model to disentangle how the features of built environment may influence the frequency of risky crossing events. The case study results show that risky street-crossing behavior is prevalent in bicycle traffic – for example, 16.94% of cycling trips are involved in illegal crossing action. Most cyclists engage in illegal crossing behavior at the approximate central part of the streets and during the day, which reveals the presence of heterogeneity over space and time. Strong correlations between commuting activities and risky street-crossing behaviors are identified from topic modeling. Meanwhile, the latent illegal crossing patterns unraveled here highlight that typical reasons for committing the risky riding action include the lure of the travel destination across the road and the inconvenience of riding round in distant legal crossing facilities. GBDT findings provide new insights on the existence of the association between built environment and cyclists' illegal crossing action. The places related employment and catering play a dominant role in contributing risky street-crossing behavior, and the influences of road length, road level, bus stop and metro station are not neglectable. Most built environment attributes show nonlinear correlations with crossing frequency. It is anticipated that this study would successfully shed a first light on the pattern of cyclists' risky street-crossing behavior at the metropolitan scale, and compliment engineering practices to improve crossing behaviors and bicycle safety.
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