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Sökning: WFRF:(Zachariae Claus)

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1.
  • Ahrensbøll-Friis, Ulrik, et al. (författare)
  • Allergic contact dermatitis from dyes used in the temple of spectacles
  • 2022
  • Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 86:1, s. 25-28
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: We observed an increasing number of patients who presented with facial or retro-auricular dermatitis after skin contact with plastic spectacles or plastic covered temples. Objectives: To identify the allergens in plastic spectacles that may cause allergic contact dermatitis. Methods: All patients with suspected allergic contact dermatitis to eyewear were tested with Solvent Orange 60 (SO60), four additionally with Solvent Yellow 14 (SY14), and five with scrapings from their own spectacles. In one case, a chemical analysis of the spectacles was performed to uncover the causative allergen. Results: Three patients were allergic to SO60, two patients to SY14, and two patients were allergic to both SO60 and SY14. Conclusion: Patients with suspected allergic contact dermatitis from spectacles should be tested with SO60 and SY14, and based on findings from previous reports, also with Solvent Red 179.
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2.
  • Bennike, Niels H., et al. (författare)
  • Allergic contact dermatitis caused by hydroperoxides of limonene and dose-response relationship-A repeated open application test (ROAT) study
  • 2019
  • Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 80:4, s. 208-216
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Contact allergy to oxidized limonene, with hydroperoxides of limonene (Lim-OOHs) as the main allergens, is common. However, high proportions of weak positive and doubtful patch test reactions have been reported. Objectives: To determine the clinical relevance, elicitation threshold and dose-response relationship of Lim-OOHs in individuals with a positive or doubtful patch test reaction to standard Lim-OOHs 0.3% pet. Methods: A multicentre 3-week double-blind vehicle-controlled repeated open application test (ROAT) study with a simulated fine fragrance containing Lim-OOHs at 1260, 420 and 140 ppm, equal to a dose/area per application of Lim-OOHs of 3.0, 0.99 and 0.33 mu g/cm(2), was performed. Results: Among 11 subjects allergic to Lim-OOHs, 11 (100%), 7 (64%), and 3 (27%), respectively, reacted to the applied doses. No reactions were seen in 17 healthy controls exposed to the highest dose. This difference in reactivity was statistically significant (P < 0.0001). Among 13 subjects with doubtful patch test reactions to Lim-OOHs, two (15%) had positive ROAT reactions to the highest Lim-OOH dose applied (P = 0.36 as compared with controls). Conclusions: Contact allergy to Lim-OOHs is of clinical relevance in patients with positive patch test reactions. A doubtful patch test reaction to Lim-OOHs 0.3% pet. can be of clinical relevance.
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3.
  • Friis, Ulrik Fischer, et al. (författare)
  • CI Solvent Yellow 14 (Sudan I) identified as the allergen in a plastic part of glasses
  • 2020
  • Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 82:3, s. 183-185
  • Tidskriftsartikel (refereegranskat)abstract
    • There have been reports of allergic contact dermatitis in response to the plastic part of eyewear. Different substances have been identified as the causative allergens: Solvent Orange 60,1 methylisothiazolinone,2 and triethylene glycol bis(−2ethylhexanoate).3 Here we present the first known case of allergic contact dermatitis caused by CI Solvent Yellow 14 (CAS no. 842–07‐9) used in the plastic part of the glasses, in the temple tips.
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