| 1. |
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- 2019
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Fu, Yifeng, 1984, et al.
(författare)
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Templated Growth of Covalently Bonded Three-Dimensional Carbon Nanotube Networks Originated from Graphene
- 2012
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Ingår i: Advanced Materials. - : Wiley. - 0935-9648 .- 1521-4095. ; 24:12, s. 1576-1581
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Tidskriftsartikel (refereegranskat)abstract
- A template-assisted method that enables the growth of covalently bonded three-dimensional carbon nanotubes (CNTs) originating from graphene at a large scale is demonstrated. Atomic force microscopy-based mechanical tests show that the covalently bonded CNT structure can effectively distribute external loading throughout the network to improve the mechanical strength of the material.
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| 3. |
- Huang, Liping, et al.
(författare)
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Interim effects of salt substitution on urinary electrolytes and blood pressure in the China Salt Substitute and Stroke Study (SSaSS).
- 2020
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Ingår i: American Heart Journal. - : Elsevier BV. - 0002-8703 .- 1097-6744. ; 221, s. 136-145
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Tidskriftsartikel (refereegranskat)abstract
- The Salt Substitute and Stroke Study is an ongoing 5-year large-scale cluster randomized trial investigating the effects of potassium-enriched salt substitute compared to usual salt on the risk of stroke. The study involves 600 villages and 20,996 individuals in rural China. Intermediate risk markers were measured in a random subsample of villages every 12 months over 3 years to track progress against key assumptions underlying study design. Measures of 24-hour urinary sodium, 24-hour urinary potassium, blood pressure and participants' use of salt substitute were recorded, with differences between intervention and control groups estimated using generalized linear mixed models. The primary outcome of annual event rate in the two groups combined was determined by dividing confirmed fatal and non-fatal strokes by total follow-up time in the first 2 years. The mean differences (95% CI) were -0.32 g (-0.68 to 0.05) for 24-hour urinary sodium, +0.77 g (+0.60 to +0.93) for 24-hour urinary potassium, -2.65 mmHg (-4.32 to -0.97) for systolic blood pressure and +0.30 mmHg (-0.72 to +1.32) for diastolic blood pressure. Use of salt substitute was reported by 97.5% in the intervention group versus 4.2% in the control group (P<.0001). The overall estimated annual event rate for fatal and non-fatal stroke was 3.2%. The systolic blood pressure difference and the annual stroke rate were both in line with the statistical assumptions underlying study design. The trial should be well placed to address the primary hypothesis at completion of follow-up.
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| 4. |
- Canelas, A.B., et al.
(författare)
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Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains
- 2010
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723 .- 2041-1723. ; 1:9
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Tidskriftsartikel (refereegranskat)abstract
- The field of systems biology is often held back by difficulties in obtaining comprehensive, high-quality, quantitative data sets. In this paper, we undertook an interlaboratory effort to generate such a data set for a very large number of cellular components in the yeast Saccharomyces cerevisiae, a widely used model organism that is also used in the production of fuels, chemicals, food ingredients and pharmaceuticals. With the current focus on biofuels and sustainability, there is much interest in harnessing this species as a general cell factory. In this study, we characterized two yeast strains, under two standard growth conditions. We ensured the high quality of the experimental data by evaluating a wide range of sampling and analytical techniques. Here we show significant differences in the maximum specific growth rate and biomass yield between the two strains. On the basis of the integrated analysis of the high-throughput data, we hypothesize that differences in phenotype are due to differences in protein metabolism.
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| 5. |
- Cao, Yuan, et al.
(författare)
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Hybrid Trusted/Untrusted Relay Based Quantum Key Distribution over Optical Backbone Networks
- 2021
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Ingår i: IEEE Journal on Selected Areas in Communications. - 0733-8716 .- 1558-0008. ; 39:9, s. 2701-2718
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Tidskriftsartikel (refereegranskat)abstract
- Quantum key distribution (QKD) has demonstrated a great potential to provide future-proofed security, especially for 5G and beyond communications. As the critical infrastructure for 5G and beyond communications, optical networks can offer a cost-effective solution to QKD deployment utilizing the existing fiber resources. In particular, measurement-device-independent QKD shows its ability to extend the secure distance with the aid of an untrusted relay. Compared to the trusted relay, the untrusted relay has obviously better security, since it does not rely on any assumption on measurement and even allows to be accessed by an eavesdropper. However, it cannot extend QKD to an arbitrary distance like the trusted relay, such that it is expected to be combined with the trusted relay for large-scale QKD deployment. In this work, we study the hybrid trusted/untrusted relay based QKD deployment over optical backbone networks and focus on cost optimization during the deployment phase. A new network architecture of hybrid trusted/untrusted relay based QKD over optical backbone networks is described, where the node structures of the trusted relay and untrusted relay are elaborated. The corresponding network, cost, and security models are formulated. To optimize the deployment cost, an integer linear programming model and a heuristic algorithm are designed. Numerical simulations verify that the cost-optimized design can significantly outperform the benchmark algorithm in terms of deployment cost and security level. Up to 25% cost saving can be achieved by deploying QKD with the hybrid trusted/untrusted relay scheme while keeping much higher security level relative to the conventional point-to-point QKD protocols that are only with the trusted relays.
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| 6. |
- Chen, Lei, 1981-, et al.
(författare)
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Mathematical Modeling for Optimal Deployment of In-Building Distributed Antenna Systems
- 2012
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Ingår i: Communications in China (ICCC), 2012. - : IEEE. - 9781467328142 ; , s. 786-791
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Konferensbidrag (refereegranskat)abstract
- In-building Distributed Antenna System (IB-DAS) has been proved to be one of the most efficient methods to provide sufficient coverage and capacity for indoor users. The target of a successful IB-DAS deployment is to guarantee the coverage as well as the capacity of the in-building areas with minimum deployment cost. We consider the optimaldeployment of the IB-DAS based on passive DAS in this paper. Mixed Integer Programming model has been developed forthe topology design of IB-DAS through the optimal installation of power splitters in order to connect all the antennas with minimum cable cost, meanwhile, the transmit power at each antenna are kept within the satisfied level for the service guarantee. The model can deliver optimal solutions to systems with a practical size where passive DAS is commonly deployed. To improve the time efficiency, preprocessing has been done to integrate the building layout data into themodeling. Application of the model over realistic IB-DAS deployment has been conducted, which demonstrates the effectiveness of the model.
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| 7. |
- Chumnanpuen, Pramote, 1983, et al.
(författare)
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Integrated analysis of transcriptome and lipid profiling reveals the co-influences of inositol-choline and Snf1 in controlling lipid biosynthesis in yeast
- 2012
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Ingår i: Molecular Genetics and Genomics. - : Springer Science and Business Media LLC. - 1617-4615 .- 1617-4623. ; 287:7, s. 541-554
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Tidskriftsartikel (refereegranskat)abstract
- In the yeast Saccharomyces cerevisiae many genes involved in lipid biosynthesis are transcriptionally controlled by inositol-choline and the protein kinase Snf1. Here we undertook a global study on how inositol-choline and Snf1 interact in controlling lipid metabolism in yeast. Using both a reference strain (CEN.PK113-7D) and a snf1 Delta strain cultured at different nutrient limitations (carbon and nitrogen), at a fixed specific growth rate of 0.1 h(-1), and at different inositol choline concentrations, we quantified the expression of genes involved in lipid biosynthesis and the fluxes towards the different lipid components. Through integrated analysis of the transcriptome, the lipid profiling and the fluxome, it was possible to obtain a high quality, large-scale dataset that could be used to identify correlations and associations between the different components. At the transcription level, Snf1 and inositol-choline interact either directly through the main phospholipid-involving transcription factors (i.e. Ino2, Ino4, and Opi1) or through other transcription factors e.g. Gis1, Mga2, and Hac1. However, there seems to be flux regulation at the enzyme levels of several lipid involving enzymes. The analysis showed the strength of using both transcriptome and lipid profiling analysis for mapping the co-influence of inositol-choline and Snf1 on phospholipid metabolism.
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| 8. |
- Fan, Qunping, et al.
(författare)
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Unidirectional Sidechain Engineering to Construct Dual-Asymmetric Acceptors for 19.23 % Efficiency Organic Solar Cells with Low Energy Loss and Efficient Charge Transfer
- 2023
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Ingår i: Angewandte Chemie International Edition. - : WILEY-V C H VERLAG GMBH. - 1433-7851 .- 1521-3773. ; 62:36
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Tidskriftsartikel (refereegranskat)abstract
- Achieving both high open-circuit voltage (V-oc) and short-circuit current density (J(sc)) to boost power-conversion efficiency (PCE) is a major challenge for organic solar cells (OSCs), wherein high energy loss (E-loss) and inefficient charge transfer usually take place. Here, three new Y-series acceptors of mono-asymmetric asy-YC11 and dual-asymmetric bi-asy-YC9 and bi-asy-YC12 are developed. They share the same asymmetric D(1)AD(2) (D-1=thieno[3,2-b]thiophene and D-2=selenopheno[3,2-b]thiophene) fused-core but have different unidirectional sidechain on D-1 side, allowing fine-tuned molecular properties, such as intermolecular interaction, packing pattern, and crystallinity. Among the binary blends, the PM6 : bi-asy-YC12 one has better morphology with appropriate phase separation and higher order packing than the PM6 : asy-YC9 and PM6 : bi-asy-YC11 ones. Therefore, the PM6 : bi-asy-YC12-based OSCs offer a higher PCE of 17.16 % with both high V-oc and J(sc), due to the reduced E-loss and efficient charge transfer properties. Inspired by the high V-oc and strong NIR-absorption, bi-asy-YC12 is introduced into efficient binary PM6 : L8-BO to construct ternary OSCs. Thanks to the broadened absorption, optimized morphology, and furtherly minimized E-loss, the PM6 : L8-BO : bi-asy-YC12-based OSCs achieve a champion PCE of 19.23 %, which is one of the highest efficiencies among these annealing-free devices. Our developed unidirectional sidechain engineering for constructing bi-asymmetric Y-series acceptors provides an approach to boost PCE of OSCs.
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| 9. |
- Liu, Linpeng, et al.
(författare)
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Ni and Fe catalyzed cascade radical reactions of oxime esters with diselenides
- 2022
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Ingår i: Organic Chemistry Frontiers. - : Royal Society of Chemistry (RSC). - 2052-4129. ; 9:13, s. 3480-3485
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Tidskriftsartikel (refereegranskat)abstract
- A radical cyclization and ring-opening of oxime esters with diselenides was developed. Both Ni(0) and Fe(II) catalysts could be employed for the selenylation of olefin-containing and cyclic oxime ester derivatives. With this method, a variety of functionalized pyrrolines and alkyl nitriles were synthesized in good yields. Moreover, a mechanism involving iminyl radical and carbon-centered radical intermediates was proposed.
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| 10. |
- Lu, Yiping, et al.
(författare)
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Directly cast bulk eutectic and near-eutectic high entropy alloys with balanced strength and ductility in a wide temperature range
- 2017
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Ingår i: Acta Materialia. - : Elsevier BV. - 1359-6454. ; 124, s. 143-150
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Tidskriftsartikel (refereegranskat)abstract
- High entropy alloys (HEAs) usually possess weak liquidity and castability, and considerable compositional inhomogeneity, mainly because they contain multiple elements with high concentrations. As a result, large-scale production of HEAs by casting is limited. To address the issue, the concept of eutectic high entropy alloys (EHEAs) was proposed, which has led to some promise in achieving good quality industrial scale HEAs ingots, and more importantly also good mechanical properties. In the practical large-scale casting, the actual composition of designed EHEAs could potentially deviate from the eutectic composition. The influence of such deviation on mechanical properties of EHEAs is important for industrial production, which constitutes the topic of the current work. Here we prepared industrial-scale HEAs ingots near the eutectic composition: hypoeutectic alloy, eutectic alloy and hypereutectic alloy. Our results showed that the deviation from eutectic composition does not significantly affect the mechanical properties, castability and the good mechanical properties of EHEAs can be achieved in a wide compositional range, and at both room and cryogenic temperatures. Our results suggested that EHEAs with simultaneous high strength and high ductility, and good liquidity and castability can be readily adapted to large-scale industrial production. The deformation behavior and microstructure evolution of the eutectic and near-eutectic HEAs were thoroughly studied using a combination of techniques, including strain measurement by digital image correlation, in-situ synchrotron X-ray diffraction, and transmission electron microscopy. The wavy strain distribution and the therefore resulted delay of necking in EHEAs were reported for the first time.
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