| 1. |
- Kerrebrouck, Joris Van, et al.
(författare)
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726.7-Gb/s 1.5-μm single-mode VCSEL discrete multi-tone transmission over 2.5-km multicore fiber
- 2018
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Ingår i: 2018 Optical Fiber Communications Conference and Exposition, OFC 2018 - Proceedings. - : Institute of Electrical and Electronics Engineers Inc.. - 9781943580385 ; , s. 1-3
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Konferensbidrag (refereegranskat)abstract
- A 107Gb/s net-rate DMT optical signal was generated using a single-mode long-wavelength VCSEL with a modulation bandwidth of 23 GHz. We experimentally demonstrated a total net-rate up to 726.7Gb/s at 1.5μm over 2.5km 7-core dispersion-uncompensated MCF.
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| 2. |
- Li, Yanying, et al.
(författare)
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A D-peptide ligand of neuropeptide Y receptor Y-1 serves as nanocarrier traversing of the blood brain barrier and targets glioma
- 2022
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Ingår i: Nano Today. - : Elsevier. - 1748-0132 .- 1878-044X. ; 44
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Tidskriftsartikel (refereegranskat)abstract
- Diseases of the central nervous system (CNS) are challenging for drug treatment because the blood-brain barrier (BBB) restricts entry of drugs into the brain tissue. Therefore, strategies for drug transport across the BBB are an important component in development of CNS drug therapies. Here, a D-amino acid ligand of the neuropeptide Y (NPY) receptor Y1 is described, (D)[Asn(28), Pro(30), Trp(32)]-DNPY (25-36) (termed DAPT), with 2.5 times higher number of hydrogen bonds interacting with the receptor, based on docking into a structural model, than the corresponding peptide with standard L-amino acids (LAPT). Using in vitro BBB models, in vivo healthy mice with intact BBB, and U87-MG orthotopic tumor-bearing mice, we demonstrate that DAPT exhibits significantly higher ability than LAPT to serve as nanocarrier across the BBB and specifically targets gliomas. Using DAPT nanomicelles loaded with IRDye780, it was possible to achieve excellent photothermal therapeutic and photoacoustic cancer imaging. Thus, this study demonstrates the importance of ligand stability and affinity in Y1 receptor-mediated transcytosis and paves the way for versatile brain tumor imaging and therapy using nanomicelles.
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| 3. |
- Xu, Weidong, et al.
(författare)
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Iodomethane-Mediated Organometal Halide Perovskite with Record Photoluminescence Lifetime
- 2016
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Ingår i: ACS Applied Materials and Interfaces. - : AMER CHEMICAL SOC. - 1944-8244 .- 1944-8252. ; 8:35, s. 23181-23189
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Tidskriftsartikel (refereegranskat)abstract
- Organometallic lead halide perovskites are excellent light harvesters for high-efficiency photovoltaic devices. However, as the key component in these devices, a perovskite thin film with good morphology and minimal trap states is still difficult to obtain. Herein we show that by incorporating a low boiling point alkyl halide such as iodomethane (CH3I) into the precursor solution, a perovskite (CH3NH3PbI3-xClx) film with improved grain size and orientation can be easily achieved. More importantly, these films exhibit a significantly reduced amount of trap states. Record photoluminescence lifetimes of more than 4 mu s are achieved; these lifetimes are significantly longer than that of pristine CH3NH3PbI3-xClx films. Planar heterojunction solar cells incorporating these CH3I-mediated perovskites have demonstrated a dramatically increased power conversion efficiency compared to the ones using pristine CH3NH3PbI3-xClx. Photoluminescence, transient absorption, and microwave detected photoconductivity measurements all provide consistent evidence that CH3I addition increases the number of excitons generated and their diffusion length, both of which assist efficient carrier transport in the photovoltaic device. The simple incorporation of alkyl halide to enhance perovskite surface passivation introduces an important direction for future progress on high efficiency perovskite optoelectronic devices.
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