1. |
- Fu, Xi, et al.
(författare)
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Microbial Virulence Factors, Antimicrobial Resistance Genes, Metabolites, and Synthetic Chemicals in Cabins of Commercial Aircraft
- 2023
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Ingår i: Metabolites. - : MDPI. - 2218-1989 .- 2218-1989. ; 13:3
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Tidskriftsartikel (refereegranskat)abstract
- Passengers are at a higher risk of respiratory infections and chronic diseases due to microbial exposure in airline cabins. However, the presence of virulence factors (VFs), antimicrobial resistance genes (ARGs), metabolites, and chemicals are yet to be studied. To address this gap, we collected dust samples from the cabins of two airlines, one with textile seats (TSC) and one with leather seats (LSC), and analyzed the exposure using shotgun metagenomics and LC/MS. Results showed that the abundances of 17 VFs and 11 risk chemicals were significantly higher in TSC than LSC (p < 0.01). The predominant VFs in TSC were related to adherence, biofilm formation, and immune modulation, mainly derived from facultative pathogens such as Haemophilus parainfluenzae and Streptococcus pneumoniae. The predominant risk chemicals in TSC included pesticides/herbicides (carbofuran, bromacil, and propazine) and detergents (triethanolamine, diethanolamine, and diethyl phthalate). The abundances of these VFs and detergents followed the trend of TSC > LSC > school classrooms (p < 0.01), potentially explaining the higher incidence of infectious and chronic inflammatory diseases in aircraft. The level of ARGs in aircraft was similar to that in school environments. This is the first multi-omic survey in commercial aircraft, highlighting that surface material choice is a potential intervention strategy for improving passenger health.
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2. |
- Meng, Lu, et al.
(författare)
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Study on the safety performance of an offshore stationary lead-cooled fast reactor design loaded with nitride fuel
- 2024
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Ingår i: Annals of Nuclear Energy. - 0306-4549 .- 1873-2100. ; 208
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Tidskriftsartikel (refereegranskat)abstract
- As a new generation of reactor type, lead-cooled fast reactors, have better safety behaviors, higher reliability, and better economic performance, aiming at island power supply through nuclear energy, seawater desalination, optimization of nuclear submarines, etc. Its evolution of nuclear waste and the advantages of nuclear non-proliferation provide a good prospect for development. This paper studied the safety performances of an offshore stationary lead-cooled reactor (OSLR) proposed in the National Key Research and Development Program of China. The transient analysis code SAS4A/SASSYS-1 was used to perform simulations of unprotected over-power accidents (UTOP) and unprotected loss of heat sink (ULOHS) accidents. The results indicated that offshore stationary lead-cooled reactors can withstand a maximum positive reactivity insertion of 0.5$ within 1 s during UTOP accidents without exceeding the working limits of the core. In ULOHS accidents, the inherent safety characteristics of OSLR allowed it to withstand 75 % heat removal capability of IHX. The simulation results were used to analyze the response of this stationary offshore reactor to transient accident conditions and the limits of its ability to withstand accidents in order to provide reference data for subsequent design and ideas for possible development of natural cycle lead-cooled reactors in the future.
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3. |
- Pecunia, Vincenzo, et al.
(författare)
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Roadmap on energy harvesting materials
- 2023
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Ingår i: Journal of Physics. - : IOP Publishing. - 2515-7639. ; 6:4
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Tidskriftsartikel (refereegranskat)abstract
- Ambient energy harvesting has great potential to contribute to sustainable development and address growing environmental challenges. Converting waste energy from energy-intensive processes and systems (e.g. combustion engines and furnaces) is crucial to reducing their environmental impact and achieving net-zero emissions. Compact energy harvesters will also be key to powering the exponentially growing smart devices ecosystem that is part of the Internet of Things, thus enabling futuristic applications that can improve our quality of life (e.g. smart homes, smart cities, smart manufacturing, and smart healthcare). To achieve these goals, innovative materials are needed to efficiently convert ambient energy into electricity through various physical mechanisms, such as the photovoltaic effect, thermoelectricity, piezoelectricity, triboelectricity, and radiofrequency wireless power transfer. By bringing together the perspectives of experts in various types of energy harvesting materials, this Roadmap provides extensive insights into recent advances and present challenges in the field. Additionally, the Roadmap analyses the key performance metrics of these technologies in relation to their ultimate energy conversion limits. Building on these insights, the Roadmap outlines promising directions for future research to fully harness the potential of energy harvesting materials for green energy anytime, anywhere.
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4. |
- Chen, Guang, et al.
(författare)
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NeuroIV : Neuromorphic Vision Meets Intelligent Vehicle Towards Safe Driving With a New Database and Baseline Evaluations
- 2022
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Ingår i: IEEE transactions on intelligent transportation systems (Print). - : Institute of Electrical and Electronics Engineers (IEEE). - 1524-9050 .- 1558-0016. ; 23:2, s. 1171-1183
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Tidskriftsartikel (refereegranskat)abstract
- Neuromorphic vision sensors such as the Dynamic and Active-pixel Vision Sensor (DAVIS) using silicon retina are inspired by biological vision, they generate streams of asynchronous events to indicate local log-intensity brightness changes. Their properties of high temporal resolution, low-bandwidth, lightweight computation, and low-latency make them a good fit for many applications of motion perception in the intelligent vehicle. However, as a younger and smaller research field compared to classical computer vision, neuromorphic vision is rarely connected with the intelligent vehicle. For this purpose, we present three novel datasets recorded with DAVIS sensors and depth sensor for the distracted driving research and focus on driver drowsiness detection, driver gaze-zone recognition, and driver hand-gesture recognition. To facilitate the comparison with classical computer vision, we record the RGB, depth and infrared data with a depth sensor simultaneously. The total volume of this dataset has 27360 samples. To unlock the potential of neuromorphic vision on the intelligent vehicle, we utilize three popular event-encoding methods to convert asynchronous event slices to event-frames and adapt state-of-the-art convolutional architectures to extensively evaluate their performances on this dataset. Together with qualitative and quantitative results, this work provides a new database and baseline evaluations named NeuroIV in cross-cutting areas of neuromorphic vision and intelligent vehicle.
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5. |
- Fan, Baobing, et al.
(författare)
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Correlation of Broad Absorption Band with Small Singlet-Triplet Energy Gap in Organic Photovoltaics
- 2023
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Ingår i: Angewandte Chemie International Edition. - : WILEY-V C H VERLAG GMBH. - 1433-7851 .- 1521-3773.
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Tidskriftsartikel (refereegranskat)abstract
- Organic photovoltaics (OPV) are one of the most effective ways to harvest renewable solar energy, with the power conversion efficiency (PCE) of the devices soaring above 19% when processed with halogenated solvents. The superior photocurrent of OPV over other emerging photovoltaics offers more opportunities to further improve the efficiency. Tailoring the absorption band of photoactive materials is an effective way to further enhance OPV photocurrent. However, the field has mostly been focusing on improving the near-infrared region photo-response, with the absorption shoulders in short-wavelength region (SWR) usually being neglected. Herein, by developing a series of non-fullerene acceptors (NFAs) with varied side-group conjugations, we observe an enhanced SWR absorption band with increased side-group conjugation length. The underpinning factors of how molecular structures and geometries improve SWR absorption are clearly elucidated through theoretical modelling and crystallography. Moreover, a clear relationship between the enhanced SWR absorption and reduced singlet-triplet energy gap is established, both of which are favorable for the OPV performance and can be tailored by rational structure design of NFAs. Finally, the rationally designed NFA, BO-TTBr, affords a decent PCE of 18.5% when processed with a non-halogenated green solvent.
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6. |
- Sun, Huaiwei, et al.
(författare)
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Drivers of the water use efficiency changes in China during 1982–2015
- 2021
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Ingår i: Science of the Total Environment. - : Elsevier BV. - 0048-9697. ; 799
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Tidskriftsartikel (refereegranskat)abstract
- This study investigates the drivers of water use efficiency (WUE), a key metric of water resources management, and its changes over eight regions across China from 1982 to 2015 based on gross primary production (GPP) and actual evapotranspiration (AET) datasets. The order of seasonal change of WUE from large to small is autumn, summer, spring and winter. The drivers include seven variables, air temperature, specific humidity, precipitation, short-wave radiation, Normalized Difference Vegetation Index (NDVI), soil moisture and CO2. Our analysis suggests that the sensitivity of annual average NDVI to WUE changes was high nationwide, but there were some differences in seasonal scales. The annual average contribution of air temperature and CO2 affecting WUE change was relatively high in China's largest area (SW, SE, E, NP). Other influencing factors were only relatively high in the local area. Seasonally, NDVI is the driving factor with the highest contribution rate in summer and autumn for NC and NW region. The seasonal contribution rates of driving factors in other regions are significantly different. For the study period (1982–2015), the shrubland ecosystem had the highest annual WUE followed by forest and cropland. The WUE of the farmland ecosystem was higher than that of the grassland ecosystem in most areas.
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7. |
- Sun, Huaiwei, et al.
(författare)
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The altered drivers of evapotranspiration trends around the recent warming hiatus in China
- 2022
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Ingår i: International Journal of Climatology. - : Wiley. - 0899-8418 .- 1097-0088. ; 42:16, s. 8405-8422
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Tidskriftsartikel (refereegranskat)abstract
- This study focuses on the trends and the causes of variation in actual evapotranspiration (AET) around the warming hiatus over China by a comprehensive analysis applying various temporal–spatial methods. It is observed that the annual AET showed a different trend around 2000 for China as a whole. By employing segmented regression analysis for detecting warming hiatus points, high temporal inconsistency can be found in eight climatic regions of China. The impacts of meteorological variables on AET were further identified by affecting the intensity and relative change of meteorological factors. AET was highly correlated (p <.01) with solar radiation in the southeast (R = 0.80) and air specific humidity in the northwest areas (R = 0.83). AET changes presented the highest sensitivity to specific humidity in Northwest before 2006 and in north central China after 2003, with sensitivity coefficients of 1.48 and 1.74, respectively. Three variables, including air specific humidity (with an average contribution rate of ~17% in the northwest), short-wave radiation and air temperature, can be the main factors that lead to the changes in AET. The specific meteorological factors varied from region to region: the changes in AET can be ascribed to the increased wind and short-wave radiation in north central China and east China, the decreased air temperature in Tibetan Plateau, the increased specific humidity in southeast China during warming hiatus, and so on. After the warming hiatus occurred, the dominant factor of AET trends changed from air specific humidity to short-wave radiation and other factors. Generally, air specific humidity and air temperature have played leading roles in AET trends during the past 30 years.
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8. |
- Wallmann, Tatjana, et al.
(författare)
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Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity
- 2018
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Ingår i: iScience. - : Elsevier BV. - 2589-0042. ; 9, s. 71-83
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Tidskriftsartikel (refereegranskat)abstract
- High-grade gliomas (HGGs) are the most aggressive and invasive primary brain tumors. The platelet-derived growth factor (PDGF) signaling pathway drives HGG progression, and enhanced expression of PDGF receptors (PDGFRs) is a well-established aberration in a subset of glioblastomas (GBMs). PDGFRA is expressed in glioma cells, whereas PDGFRB is mostly restricted to the glioma-associated stroma. Here we show that the spatial location of TAMMs correlates with the expansion of a subset of tumor cells that have acquired expression of PDGFRB in both mouse and human low-grade glioma and HCGs. Furthermore, M2-polarized microglia but not bone marrow (BM)-derived macrophages (BMDMs) induced PDGFRB expression in glioma cells and stimulated their migratory capacity. These findings illustrate a heterotypic cross-talk between microglia and glioma cells that may enhance the migratory and invasive capacity of the latter by inducing PDGFRB.
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9. |
- Yang, Zhimo, et al.
(författare)
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Facile synthesis of Fe-doped Sn4P3 anode materials for high-performance lithium-ion batteries
- 2023
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Ingår i: Solid State Sciences. - : Elsevier BV. - 1293-2558 .- 1873-3085. ; 136
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Tidskriftsartikel (refereegranskat)abstract
- Metal doping plays a momentous role in heightening the electronic conductivity of Sn4P3. This work proposes the facile synthesis of Fe-doped Sn4P3 via a solid-state reaction process. The resulting Fe-doped Sn4P3 is stacked by a great quantity of nanoparticles. As the ionic radius of Fe3+ (64.5 p.m.) is slightly smaller than that of Sn4+ (69 p.m.), Fe3+can easily dope into the structure of Sn4P3. The Sn4P3 anode with 5% Fe doping delivers a larger initial discharge capacity of 1105.1 mAh/g and coloumbic efficiency of 86.2%. After 200 cycles, a high discharge capacity of 972.4 mAh/g is reached, while the discharge capacity of un-doped Sn4P3 anode merely maintains at about 423.3 mAh/g. As an inactive matrix, Fe atoms can disperse among Sn atoms, thus inhibiting the aggregation of Sn atoms during cycling. The results display that Fe doping in Sn4P3 structure is extremely vital to heighten the architecture stability and electrochemical performance. This facile solid-state reaction process can be enlarged to the manufacture of other metal-doped Sn4P3 in the field of lithium-ion batteries.
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