| 1. |
- Jung, Christian, et al.
(författare)
-
A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention
- 2019
-
Ingår i: Journal of critical care. - : W B SAUNDERS CO-ELSEVIER INC. - 0883-9441 .- 1557-8615. ; 52, s. 141-148
-
Tidskriftsartikel (refereegranskat)abstract
- Background: We aimed to evaluate differences in outcome between patients admitted to intensive care unit (ICU) after elective versus acute surgery in a multinational cohort of very old patients (80 years; VIP). Predictors of mortality, with special emphasis on frailty, were assessed.Methods: In total, 5063 VIPs were induded in this analysis, 922 were admitted after elective surgery or intervention, 4141 acutely, with 402 after acute surgery. Differences were calculated using Mann-Whitney-U test and Wilcoxon test. Univariate and multivariable logistic regression were used to assess associations with mortality.Results: Compared patients admitted after acute surgery, patients admitted after elective surgery suffered less often from frailty as defined as CFS (28% vs 46%; p < 0.001), evidenced lower SOFA scores (4 +/- 5 vs 7 +/- 7; p < 0.001). Presence of frailty (CFS >4) was associated with significantly increased mortality both in elective surgery patients (7% vs 12%; p = 0.01), in acute surgery (7% vs 12%; p = 0.02).Conclusions: VIPs admitted to ICU after elective surgery evidenced favorable outcome over patients after acute surgery even after correction for relevant confounders. Frailty might be used to guide clinicians in risk stratification in both patients admitted after elective and acute surgery.
|
|
| 2. |
- Joshi, Siddarth Koduru, et al.
(författare)
-
Space QUEST mission proposal : experimentally testing decoherence due to gravity
- 2018
-
Ingår i: New Journal of Physics. - : IOP Publishing. - 1367-2630. ; 20
-
Tidskriftsartikel (refereegranskat)abstract
- Models of quantum systems on curved space-times lack sufficient experimental verification. Some speculative theories suggest that quantum correlations, such as entanglement, may exhibit different behavior to purely classical correlations in curved space. By measuring this effect or lack thereof, we can test the hypotheses behind several such models. For instance, as predicted by Ralph et al [5] and Ralph and Pienaar [1], a bipartite entangled system could decohere if each particle traversed through a different gravitational field gradient. We propose to study this effect in a ground to space uplink scenario. We extend the above theoretical predictions of Ralph and coworkers and discuss the scientific consequences of detecting/failing to detect the predicted gravitational decoherence. We present a detailed mission design of the European Space Agency's Space QUEST (Space-Quantum Entanglement Space Test) mission, and study the feasibility of the mission scheme.
|
|
| 3. |
- Pioro, Michal, et al.
(författare)
-
Optimized IP-based vs. explicit paths for one-to-one backup in MPLS fast reroute
- 2010
-
Konferensbidrag (refereegranskat)abstract
- Primary and backup paths in MPLS fast reroute (FRR) may be established as shortest paths according to the administrative link costs of the IP control plane, or as explicitly calculated arbitrary paths. In both cases, the path layout can be optimized so that the maximum link utilization for a set of considered failure scenarios is minimized. In this paper, we propose a linear program for the optimization of the path layout for explicitly calculated paths, which can either produce single paths and route entire traffic along those paths, or generate multiple paths and spread the traffic among those paths providing load balancing. We compare the resulting lowest maximum link utilization in both cases with the lowest maximum link utilization that can be obtained by optimizing unique IP-based paths. Our results quantify the gain in resource efficiency usage provided by optimized explicit multiple paths or explicit single paths as compared to optimized IP-based paths.
|
|
| 4. |
- Żukowski, C., et al.
(författare)
-
Compact Node-Link Formulations for the Optimal Single-Path MPLS Fact Reroute Layout
- 2011
-
Ingår i: Advances in Electronics and Telecommunications. - 2081-8580. ; 2:3, s. 55-60
-
Tidskriftsartikel (refereegranskat)abstract
- This paper discusses compact node-link formulations for MPLS fast reroute optimal single path layout. We propose mathematical formulations for MPLS fast reroute local protection mechanisms. In fact, we compare one-to-one (also called detour) local protection and many-to-one (also called facility backup) local protection mechanisms with respect to minimized maximum link utilization. The optimal results provided by the node-links are compared with the suboptimal results provided by algorithms based on non-compact linear programming (path generation) approach and IP-based approach.
|
|
