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- Thomas, HS, et al.
(författare)
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- 2019
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swepub:Mat__t
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- Drake, TM, et al.
(författare)
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Surgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study
- 2020
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Ingår i: BMJ global health. - : BMJ. - 2059-7908. ; 5:12
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Tidskriftsartikel (refereegranskat)abstract
- Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings.MethodsA multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI).ResultsOf 1159 children across 181 hospitals in 51 countries, 523 (45·1%) children were from high HDI, 397 (34·2%) from middle HDI and 239 (20·6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12·8% (51/397) in middle HDI and 24·7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI.ConclusionThe odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.
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- Amirah Hamzah, Hamizah, et al.
(författare)
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Heavy metal speciation in surface sediments and their impact on the bioaccumulation of green mussels (Perna viridis) from the eastern part of the Straits of Johor, Malaysia
- 2023
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Ingår i: Total Environment Research Themes. - : Elsevier. - 2772-8099. ; 7
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Tidskriftsartikel (refereegranskat)abstract
- Many aquatic ecosystems are vulnerable to many pollutants, particularly heavy metals that are now a threat to public health. It may be more effective to manage pollution in waterways if we can better understand the connection between heavy metals in sediments and their accumulation in green mussels. In this study, lead levels in green mussels (Perna viridis) were above the permissible maximum level (WHO, Malaysia Food Regulation, and the FAO). Moreover, zinc levels exceeded the FAO's maximum recommended range. The fractionate of heavy metals in surface sediment from the eastern part of the Johore Straits was investigated using the sequential extraction techniques (SET) method. In the majority of sampling stations, copper's chemical speciation followed the following order: residual > oxidisable-organic > exchangeable > acid reducible, while zinc's and lead's chemical speciation followed the following pattern: residual > oxidisable-organic > acid reducible > exchangeable. The results of Pearson's correlation studies demonstrated a substantial association between Zn concentration in the tissues of green mussels and total Zinc, exchangeable (F1), acid-reducible (F2), and residual (F4) Zn in surface sediment. Green mussel Cu content and surface sediment Cu of exchangeable (F1), residual (F4), and total Cu were found to correlate. As a result, green mussels are being used as a biomonitoring agent for heavy metal contamination on the eastern side of the Straits of Johor in Malaysia.
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