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1.
  • Bergknut, Niklas (författare)
  • Pedicle Screw-Rod Fixation of the Canine Lumbosacral Junction
  • 2012
  • Ingår i: Veterinary Surgery. - 0161-3499 .- 1532-950X. ; 41, s. 720-732
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective To assess pedicle screw-rod fixation (PSRF) of the canine lumbosacral junction (LSJ) ex vivo and in vivo. Study Design Ex vivo cadaver study and in vivo pilot study. Sample Population Six canine cadaveric lumbosacral spinal specimens and 3 Greyhound dogs diagnosed with degenerative lumbosacral stenosis (DLSS). Methods Ex vivo study: PSRF of the LSJ was performed in 6 spinal specimens using guidelines and was evaluated by radiography, computed tomography, and magnetic resonance imaging. In vivo study: 3 Greyhounds diagnosed with DLSS had dorsal laminectomy and partial discectomy combined with PSRF of the LSJ. Curettage of the endplates with insertion of an autologous cancellous bone graft was performed to promote spinal fusion. During 18-month follow-up, dogs were monitored by clinical evaluation, diagnostic imaging, and force plate analysis. Dogs were euthanatized for reasons unrelated to PSRF or their lumbosacral disease, and postmortem imaging and histopathologic investigations of the LSJ were performed. Results Ex vivo study: Sixteen of 24 inserted screws had an acceptable placement. In vivo study: Ten of 12 inserted screws had acceptable placement. Clinical signs of ``lower'' back pain resolved at 4 weeks after surgery. Diagnostic imaging and histopathology showed no bony spinal fusion of the LSJ. Force plate analysis revealed a trend toward improved pelvic limb function relative to preoperative function. Conclusions PSRF of the LSJ of large breed dogs is technically possible. Improvements to the surgical technique to induce spinal fusion and assessment in a larger sample size are required before it can be recommended.
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2.
  • Bergknut, Niklas, et al. (författare)
  • Soft Tissue Artifact in Canine Kinematic Gait Analysis
  • 2012
  • Ingår i: Veterinary Surgery. - 0161-3499 .- 1532-950X. ; 41, s. 829-837
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective To investigate, noninvasively, the soft tissue artifact (STA) in canine kinematic gait analysis. Study Design Experimental study. Animals Labrador retrievers (n = 4). Methods Kinematic study: Reflective markers were glued to the skin over bony landmarks, with the distance between 2 markers representing the length of the underlying scapula, humerus, ulna, femur, and crus. The distance between these markers (marker distance [MD]) was measured with infrared cameras while the dogs stood still or walked on a treadmill. Fluoroscopy study: Radiopaque markers were glued on the skin over the spinous process of the L6 vertebra and the stifle to allow fluoroscopic observation of the markers and underlying skeletal segments while the dogs walked on the treadmill. The position of the markers was compared with the position of the underlying skeletal segments during different phases of the step cycle. Results Kinematic study: Significant differences were found between MD during standing and walking for all bones investigated. Mean percentage differences in MD ranged from 18% to +6%. Fluoroscopy study: Significant displacements relative to the bony landmarks were found ranging from 0.4 to 1.2 cm. Conclusions Analysis of the motion of skeletal structures with the use of markers attached to the skin showed that the skin moves relative to underlying skeletal structures. When working with a 3-D motion-capture system using skin markers, researchers should be aware that the STA could significantly influence their results.
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3.
  • Höglund, Odd, et al. (författare)
  • Intraoperative Changes in Blood Pressure, Heart Rate, Plasma Vasopressin, and Urinary Noradrenalin During Elective Ovariohysterectomy in Dogs : Repeatability at Removal of the 1st and 2nd Ovary
  • 2014
  • Ingår i: Veterinary Surgery. - 0161-3499 .- 1532-950X. ; 43, s. 852-859
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: whether this is repeated during removal of the 2nd ovary in elective ovariohysterectomy.To investigate the physiologic reactions after removal of 1st ovary and Study Design:Prospective study. Animals:Dogs (n¼10). Methods: anesthetized with propofol and iso iso during surgery on physiologic variables were analyzed using mixed linear models. Blood and urine samples were collected before anesthesia, before incision, before and after removal of ovaries with a 15 minute pause between ovary removal, and after abdominal closure. Plasma vasopressin and urinary noradrenalin and creatinine concentrations were analyzed.Dogs were premedicated with acepromazine, carprofen, and methadone andflurane. Blood pressure, heart rate, and end‐tidalflurane concentration were measured every minute. The effects of various events Results: greater than for the 2nd ovary because of an elevation in baseline. Similarly, the heart rate increased at the removal of the 1st ovary but not at removal of the 2nd ovary. Plasma vasopressin concentration increased at removal of both ovaries. Urinary noradrenalin/ creatinine ratio increased at anesthesia, removal of both ovaries, and was elevated at closure of the abdomen. End pressure and vasopressin concentrations changed in parallel using z comparison.The magnitude of blood pressure increase at removal of the 1st ovary was‐tidal isoflurane concentration did not change. Blood‐scores for Conclusions: concentration, and urinary noradrenalin/creatinine ratio did not differ between removals of the ovaries. Relative changes differed between repeated noxious stimuli, which should be considered in evaluation of methods at ovary removal.Peak values for blood pressure, heart rate, plasma vasopressin
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  • Bergström, Annika, et al. (författare)
  • Reduction of Surgical Complications in Dogs and Cats by the Use of a Surgical Safety Checklist
  • 2016
  • Ingår i: Veterinary Surgery. - : Wiley. - 0161-3499 .- 1532-950X. ; 45, s. 571-576
  • Tidskriftsartikel (refereegranskat)abstract
    • ObjectiveTo examine whether the use of a surgical safety checklist (SSC) could reduce the incidence of complications after small animal surgery.Study DesignProspective clinical study. Animals: Client-owned dogs and cats (n=520).MethodsConsecutive cases were enrolled in the study, the first 300 cases without implementation of the surgical checklist (SSC-), followed by 220 cases with implementation of the checklist (SSC+). The checklist was adapted from the WHO surgical checklist and consisted of three different check points: (1) before induction of anaesthesia (sign in), (2) before surgical incision (time out), and (3) before recovery (sign out). In-hospital outcomes were prospectively recorded, and complications within 6 weeks were retrospectively recorded by reviewing medical records and by telephone interviews with owners. The severity of each recorded complication was graded as minor, moderate, or severe. Comparisons were made between SSC- and SSC+ outcomes.ResultsThere were significantly more complications in SSC- animals than SSC+ animals (SSC- 52/300 vs. SSC+ 15/220, P=.0003). There was a significantly higher frequency of SSI (P=.045) and wound healing complications (P=.0006) for SSC- animals than SSC+ animals.ConclusionThe frequency and severity of postoperative complications was significantly decreased after introduction of a surgical checklist. All veterinary hospitals should consider using a surgical checklist. Compliance with implementation of the checklist is important for success.
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6.
  • Comino, Francesco, et al. (författare)
  • Standing laparoscopy combined with a conventional inguinal approach to treat extended septic funiculitis in 12 horses
  • 2022
  • Ingår i: Veterinary Surgery. - : Wiley. - 0161-3499 .- 1532-950X. ; 51, s. 853-858
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective To describe a 2-step surgical procedure combining standing laparoscopy with a conventional inguinal approach to treat deep intra-abdominal funiculitis (extended septic funiculitis) after castration. Study design Retrospective case series. Sample population Twelve client-owned horses. Methods Medical records of horses treated for extended septic funiculitis with the 2-step surgical procedure were reviewed. Data collected included the initial castration technique, number of surgical interventions for septic funiculitis prior to presentation, clinical signs, diagnostic and surgical procedure, and short-term and long-term survival. Results Complete resection of the infected spermatic cord was achieved without intraoperative complications. Intra-abdominal adhesions were documented in 6 horses, involving the ascending colon (4 cases) and descending colon (2 cases). Postoperatively, minor incisional swelling (2/12) and emphysema (3/12) at the laparoscopic portals were observed. All horses survived to discharge. At 3 months, wounds had completely healed without complications. No recurrence of signs was recorded at long-term follow up (4-36 months after discharge). Conclusion In cases of extended septic funiculitis, complete resection of the infected spermatic cord can be safely performed using a laparoscopic-assisted surgical approach, reducing postoperative complications and risk of recurrence of infection.
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7.
  • Höglund, Odd, et al. (författare)
  • A Self-locking Implant for Short-Term Use as an Alternative to Purse-String Suture in Colon Anastomosis
  • 2015
  • Ingår i: Veterinary Surgery. - 0161-3499 .- 1532-950X. ; 44, s. E55-E55
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • Colorectal cancer is common in humans where treatment involves surgical removal of the cancerous part of the intestines. A new short term implant, based on the principle of a self-locking loop, was developed to replace the purse string suture for temporary sealing of the lumen in colon anastomosis. The aim of this in vivo study was to test the self-locking implant, in conjunction with a new suture-free method (Adaptive Anaerobic Anastomosis) and the traditional circular staplers, to perform colonic anastomosis. A flexible band with a locking mechanism was constructed. Small protrusions, designed for increased friction between implant and tissue, were added to one side of the flexible band in order to enhance the grip at closure of the loop around tissue. The in vivo test was performed on six female pigs of approximately 50 kg, where the self-locking implant was used for closure of the lumen around anvils and trocars. Adaptive Anaerobic Anastomosis (n=3) and traditional circular stapler anastomosis (n=3). The self-locking implant could close the lumen of colon around the anvil and trocar of both tested techniques. Subjectively, the device achieved a tight closure of the colon. The technology was perceived as potentially timesaving and easy to use. We conclude the device may be an alternative to the traditional purse-string suture for temporary closure of the colon lumen in colon anastomosis.
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8.
  • Höglund, Odd, et al. (författare)
  • A surgical selflocking loop tested for colon anastomosis.
  • 2015
  • Ingår i: Veterinary Surgery. - 0161-3499 .- 1532-950X. ; 44, s. E34-E34
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • Introduction Colorectal cancer is common in humans. After removal of the pathologic part of the colon, leakage at the site of anastomosis is a frequently reported complication. A new suture-free method for anastomosis of the colon has been developed, CARP (Compression Anastomotic Ring-locking Procedure). The use of staplers, the traditional method to seal the lumen of colon, may interfere with the CARP method. A new technology, based on the principle of a self-locking loop, was therefore developed for temporary sealing of the lumen i conjunction with the CARP method. The aim of this in vitro and in vivo study was to test the self-locking loop with the CARP implant for closure of the colon. Materials and methods A flexible band with a case containing a locking mechanism was constructed. Studs were added to one side of the flexible band in order to enhance the tissue grip at closure of the loop around tissue. Fresh intestines (lukewarm) from a pig were used in this cadaver test. The colon was transected approximately 15 cm from the anus. The CARP implant (anvil) was inserted into the lumen. The self-locking loop was placed around the transected colon and the loop was tightened around the CARP implant inside the lumen. The closure was visually inspected and the locked loop was removed for inspection of the compressed colonic tissue. The procedure was repeated ten times. The test was repeated in vivo in four pigs of approximately 50 kg, where the self-locking loop was used for closure of the lumen in conjunction with both CARP and circular stapler anastomosis. Results The self-locking implant could close the colonic lumen around the anvil in both the in vitro (n=10) and in vivo (n=8) model. Subjectively, the device achieved a tight closure of the colon and no damage to the intestines was seen on visual inspection at removal of the self-locking implant. Discussion/conclusion Subjectively, the technology was perceived as potentially timesaving and easy to use. The self-locking loop may be an alternative to staplers or purse-string closure for temporary closure of the colon lumen in conjunction with the CARP method. Further development, such as designing a tool for tightening the loop in a laparoscopic procedure, should be addressed.
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9.
  • Höglund, Odd (författare)
  • Adjunctive fixation of the humeral epicondyle in a lateral condylar fracture model: Ex vivo comparison of pins and plates with a novel composite (AdhFix)
  • 2024
  • Ingår i: Veterinary Surgery. - 0161-3499 .- 1532-950X. ; 53, s. 311-319
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To compare the biomechanical properties of using a novel composite construct (AdhFix) to an interfragmentary Kirschner wire or a reconstruction plate as adjunctive epicondylar stabilization in simulated lateral unicondylar humeral fractures.Study design: Cadaveric biomechanical assessment.Sample population: Paired humeri harvested from skeletally mature dogs (14-41 kg), nine cadavers per group.Methods: Simulated lateral unicondylar humeral fractures were stabilized with a transcondylar 4.5 mm cortical screw placed in lag fashion. Adjunct fixations consisting of a novel composite incorporating 2.7 mm cortical screws on one side, and either a 2.7 mm reconstruction plate or a 1.6 mm Kirschner wire on the contralateral side, were tested within paired humeri. Repaired humeri were axially loaded to failure and construct stiffness, yield load, and ultimate load were obtained from the load-deformation curves.Results: In pairwise comparison, yield load was significantly higher for AdhFix group compared to the pin group, p = .016. No statistical significance was seen in the comparison between AdhFix group and the plate group, p = .25.Conclusion: Adhfix was mechanically superior to K-wires, and comparable to plate fixation, for adjunctive fixation in a lateral humeral condylar model. Our results support further investigation of the novel composite for adjunct fracture fixation in lateral humeral condylar fractures.Clinical significance: The novel composite tested may be a viable alternative for adjunct fixation of humeral condylar fractures, a technique that circumvents plate contouring.
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  • Höglund, Odd (författare)
  • Evaluation of a resorbable self-locking ligation device for performing peripheral lung biopsies in a caprine cadaveric model
  • 2019
  • Ingår i: Veterinary Surgery. - : Wiley. - 0161-3499 .- 1532-950X. ; 48, s. 845-849
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective To compare airway leak pressures after sealing peripheral lung biopsy sites with a resorbable ligation device (LigaTie) or thoracoabdominal (TA) staples. Study design Ex vivo study. Animals Four normal caprine cadavers. Methods Twelve lung lobes were harvested from 4 goats immediately after euthanasia. Each lobe was inflated to 20 cm H2O to test for leaks prior to biopsy. Pressure was then maintained at 10 cm H2O. Biopsy samples were obtained 3 cm from the periphery with a resorbable ligation device or a TA stapler (n = 6 per group). After biopsy, inflation pressure was slowly increased to 40 cm H2O while lungs were submerged in water. The pressure at which bubbles were first seen was recorded as the airway leak pressure. The length, width, volume, and weight were recorded for each biopsy sample. Results Five of 6 LigaTie biopsy sites sustained the maximum pressure of 40 cm H2O without leaking. One site leaked at 24 cm H2O. The TA-stapled sites sustained airway pressure to median 25.5 cm H2O (interquartile range, 23.5-26 cm H2O), and none of them reached the maximum pressure (P = .015). There were no differences in biopsy length, volume, or weight between groups. Conclusion Biopsy sites sealed with LigaTie withstood higher airway pressure without leaking compared with TA-stapled biopsy sites in normal cadaveric specimens. Clinical significance The LigaTie may be an alternative technique for sealing peripheral lung biopsy sites.
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12.
  • Höglund, Odd (författare)
  • Laparoscopic cryptorchidectomy using a resorbable self-locking loop device in dorsally recumbent horses
  • 2024
  • Ingår i: Veterinary Surgery. - 0161-3499 .- 1532-950X. ; 53, s. 357-366
  • Tidskriftsartikel (refereegranskat)abstract
    • ObjectiveTo report the use and feasibility of a self-locking resorbable loop device for cryptorchidectomy. Study designClinical prospective study. PopulationTwenty horses. MethodsHorses suspected to have an abdominal testicle/s after admission work-up were enrolled. Horses were anesthetized in dorsal recumbency and a standard laparoscopic technique was performed. The looped device was inserted into the abdomen, glided around the testis/cord and tightened. Then, the spermatic cord was transected prior testis removal. Surgical procedure details and remarks, perioperative complications and total surgical time were recorded. Short- (>3 weeks) and long-term (>6 months) follow-ups were obtained by telephone questionnaire. ResultsMedian total surgical time was 67 min (range: 43-189 min) and significantly shortened after the first four horses. The loop device was easily glided around 13/20 abdominal testes and required more time and technical skills around larger testes (& GE;3 years). Excellent intraoperative hemostasis was achieved in 17 horses. Three horses demonstrated mild intraoperative bleeding that required retightening, device replacement or adding a second device, respectively. Three horses developed mild postoperative hemoabdomen identified ultrasonographically and were successfully managed medically. Follow-up revealed no significant complications related to the procedure. One horse was euthanized for colic 4 months after surgery and one died of hemolytic shock 17 months postoperatively. ConclusionThis device represents another method to perform equine cryptorchidectomy that requires minimal training and laparoscopic expertise but demands knowledge of the device and application to prevent complications. Clinical significanceLaparoscopic cryptorchidectomy using this device is an alternative technique for horses <3 years.
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15.
  • Höglund, Odd (författare)
  • Resorbable self-locking device for canine lung lobectomy: A clinical and experimental study
  • 2021
  • Ingår i: Veterinary Surgery. - : Wiley. - 0161-3499 .- 1532-950X. ; 50, s. O32-O39
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective To test the feasibility of a resorbable self-locking device for sealing of lung tissue in lung lobectomy in experimental dogs and dogs with pulmonary mass, and to study its resorption with CT.Study design Experimental study and clinical case series.Animals Five beagles in the experimental group; six canine patients with a pulmonary mass in the clinical group.Methods In both groups, an intercostal incision into thorax was performed. A resorbable self-locking device, LigaTie, was applied at the hilum of left cranial lobe in the experimental group and the affected lobe in the clinical group. Each lobe was removed by cutting the tissue just distal to the device. Video-assisted thoracic surgery was used in the experimental group; postoperative diagnostic imaging was repeated monthly until the device was not apparent on CT.Results Application of LigaTie was feasible for lung lobectomy in all dogs. The device enabled en bloc ligation of the hilum of the affected lobe including the pulmonary arteries and veins and lobular bronchus. No air leakage from the resection stump was observed in any dog. Trace of the device on CT images gradually decreased and was undetectable at 4 months postoperatively in experimental dogs.Conclusion This study suggested that the resorbable self-locking device may be used for sealing of airways in complete lung lobectomy.Clinical relevance The resorbable self-locking device is suggested to be useful for canine lung lobectomy and may facilitate thoracoscopic lung lobectomy. Further investigations on its clinical application in small animal surgery are warranted.
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  • Höglund, Odd (författare)
  • Thoracoscopic-assisted lung lobectomy in cat cadavers using a resorbable self-locking ligation device
  • 2019
  • Ingår i: Veterinary Surgery. - : Wiley. - 0161-3499 .- 1532-950X. ; 48, s. 563-569
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective To compare the maximum pressure sustained by airways sealed with a resorbable ligation device (LigaTie) and with thoracoabdominal (TA) staples during thoracoscopic-assisted hilar lung lobectomies. Study design In situ cadaveric study. Animals Ten feline cadavers. Methods Twenty lung lobectomies were performed with either a LigaTie or a TA stapler (n = 10 per group) by using a thoracoscopic-assisted technique. Procedures were randomly performed on the cranial lung lobes only. The distance between the ligation and the hilus was measured on each specimen. Airway pressures were tested to a maximum pressure of 40 cmH(2)O. Results All LigaTie sites reached a maximum airway pressure without leaking and were easily placed at the hilus. Four of 10 TA stapled sites leaked at a mean pressure of 22 cmH(2)O (P = .010). All leaks occurred when the TA staple line was >5 mm from the hilus; no leaks occurred when the TA staple line was <= 5 mm from the hilus (P < .001). No difference was found between fresh and frozen cadavers (P = .483) or right vs left lung lobe (P = .284). Conclusion Lung lobectomies were consistently performed at the hilus only when the LigaTie was used. Lung lobectomies were less likely to leak when performed with the LigaTie rather compared with TA staples. Clinical significance The LigaTie may be an effective alternative for lung lobectomies at the pulmonary hilus in cats and small breed dogs. Our findings provide justification for additional clinical testing.
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  • Palmer, Michael, et al. (författare)
  • Strong Resorbable Glue for Tarsal Arthrodesis
  • 2022
  • Ingår i: Veterinary Surgery. - : Wiley. - 0161-3499 .- 1532-950X. ; 51, s. 48-48
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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20.
  • Skov Hansen, Sabrina, et al. (författare)
  • The influence of tenoscopic approaches on radiocarpal joint perforation during carpal sheath tenoscopy in horses
  • 2020
  • Ingår i: Veterinary Surgery. - : Wiley. - 0161-3499 .- 1532-950X. ; 49, s. 274-280
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective To report the frequency of radiocarpal joint (RCJ) perforation during two proximolateral carpal sheath (CS) approaches and to investigate whether the presence or absence of a natural communication between the RCJ and CS. Study design Experimental, randomized, controlled study. Sample population Twelve adult horses and 12 cadaver front limbs. Methods Proximolateral CS tenoscopy was performed on both carpi of 12 horses under general anaesthesia. Limbs were randomly assigned into two groups. In group 1, the instrument portal was centered at the level of the distal radial physeal remnant (PR). In group 2, the instrument portal was centered 2 cm proximal to the PR. Immediately after tenoscopy, dye-coloured fluid was instilled arthroscopically into the dorsolateral RCJ, and the open tenoscopic portals were evaluated for leakage. Twelve cadaver front limbs were examined for naturally occuring RCJ and CS communication by using positive-contrast computed tomography (CT). Frequency of perforations were compared with McNemar's test for two matched proportions. Results In group 1, 10 of 12 RCJ were perforated during tenoscopy, and, in group 2, four of 12 RCJ were perforated (P = 0.03). No diffusion of contrast from the RCJ to the CS was detected by CT. Conclusion Perforation of the RCJ was common when CS instrument portals were placed at the level of the PR. No natural communication was detected between the RCJ and CS. Clinical significance Carpal sheath tenoscopic instrument portals may need to be placed >2 cm proximal to the PR to prevent inadvertent RCJ perforation, especially in horses undergoing tenoscopic treatment of a septic CS.
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21.
  • Smith, Matthew R W, et al. (författare)
  • Increased Cartilage Oligomeric Matrix Protein Concentrations in Equine Digital Flexor Tendon Sheath Synovial Fluid Predicts Intrathecal Tendon Damage.
  • 2011
  • Ingår i: Veterinary surgery : VS : the official journal of the American College of Veterinary Surgeons. - 1532-950X. ; Dec, s. 54-58
  • Tidskriftsartikel (refereegranskat)abstract
    • Objectives: To evaluate digital flexor tendon sheath (DFTS) synovial fluid cartilage oligomeric matrix protein (COMP) concentrations as a molecular marker for intrathecal pathology. Study Design: Case control study. Animals: Horses (n=46) with DFTS tenosynovitis; 23 fresh cadaver horses. Methods: DFTS synovial fluid samples were collected from clinical cases with noninfected DFTS tenosynovitis and from control DFTS. Clinical and surgical findings were recorded, and dissection of control limbs was performed to confirm the DFTS to be grossly normal. Synovial fluid COMP was quantified using a homologous competitive inhibition ELISA. Results: Abnormalities were identified tenoscopically: intrathecal tendon/ligament tearing was identified in 37 cases and 9 had other lesions. In control horses, synovial fluid COMP was higher in younger horses. Clinical cases with intrathecal tendon/ligament tearing had higher synovial fluid COMP than either clinical cases with other lesions, or controls. In horses ≥5 years old, the sensitivity and specificity of the assay was high for diagnosing intrathecal tendon/ligament tearing. Conclusions: COMP concentrations in DFTS synovial fluid were significantly greater than those in normal horses with noninfected tenosynovitis caused by intrathecal tendon/ligament tearing, but not by other lesions.
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