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| 5. |
- Ledin, Torbjörn, et al.
(författare)
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Chronic toxic encephalopathy investigated using dynamic posturography
- 1991
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Ingår i: American Journal of Otolaryngology. - 0196-0709 .- 1532-818X. ; 12:2, s. 96-100
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Tidskriftsartikel (refereegranskat)abstract
- Seven male patients previously exposed to industrial solvents and diagnosed with chronic toxic encephalopathy (aged 38 to 69 years; mean age, 56 years) were investigated by dynamic posturography and compared with healthy, age-matched male control patients. Dynamic posturography comprises two phases: a sensory organization (SO) phase, in which the support surface and visual surround are either stable or referenced to the patient's sway, with eyes open or closed, and a movement coordination (MC) phase, in which the platform makes active movements. In SO testing, the patient group showed significantly impaired equilibrium performance compared with the control group in most test conditions. The MC test revealed no differences between groups. A relationship was found between the equilibrium score resulting from SO testing with stable support and visual surround and the sway area of the confidence ellipse elicited 3 years previously by static posturography with eyes open. We conclude that patients with chronic toxic encephalopathy have impaired equilibrium, as demonstrated by dynamic posturography testing.
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| 6. |
- Ledin, Torbjörn, et al.
(författare)
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Posturography findings in workers exposed to industrial solvents
- 1989
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Ingår i: Acta Oto-Laryngologica. - : Informa UK Limited. - 0001-6489 .- 1651-2251. ; 107:5-6, s. 357-361
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Tidskriftsartikel (refereegranskat)abstract
- Postural control was investigated by static posturography in 18 workers exposed to industrial solvents, 9 patients with psycho-organic syndrome due to industrial solvent exposure, and 52 controls. Both groups of exposed subjects showed larger sway areas with eyes open as well as closed, compared with the controls. No differences were found in the Romberg quotient (the relationship between sway areas with eyes closed/open). The correlation between static posturography and the otoneurological test battery was positive for the visual suppression test in the styrene group. In the industrial solvent group no significant correlations were found. The visual suppression test and some auditory tests were pathological in the exposed groups. The otoneurological test battery—especially the visual suppression test and static posturography—seems to contribute in the assessment of solvent related CNS lesions.
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- Möller, Claes, 1950-, et al.
(författare)
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Influence of age on the broad frequency rotatory test
- 1988
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Ingår i: Basics of neurootology and applied neurootological dignostics in presbyvertigo, presbyataxia and presbytinnitus. - Hamburg : Verner Rudat. ; , s. 65-70
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Konferensbidrag (refereegranskat)
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| 9. |
- Möller, Claes, 1950-, et al.
(författare)
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Otoneurological findings in workers exposed to styrene
- 1990
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Ingår i: Scandinavian Journal of Work, Environment and Health. - : Scandinavian Journal of Work, Environment and Health. - 0355-3140 .- 1795-990X. ; 16:3, s. 189-194
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Tidskriftsartikel (refereegranskat)abstract
- An otoneurological test battery was administered to 18 workers with long-term exposure (6-15 years) to styrene at levels well below the current Swedish limit (110 mg/m3). The results were compared with those of a reference group. Disturbances were found in the central auditory pathways of seven workers. Tests reflecting central processing of impulses from different sensory equilibrium organs were abnormal for 16 workers. The most relevant tests seemed to be static posturography and the rotatory visual suppression test. In the posturography the styrene group had a significantly larger sway area than the reference group. In the visual suppression test, the styrene workers displayed a significantly poorer ability to suppress vestibular nystagmus than the reference group. It was concluded that styrene exposure in industrial environments at moderate or low levels causes central nervous system disturbances which are not always diagnosable with psychometric tests but can be apparent in special otoneurological tests.
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| 10. |
- Möller, Claes, 1950-, et al.
(författare)
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The plasticity of compensatory eye movements in bilateral vestibular loss : a study with low and high frequency rotatory tests
- 1989
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Ingår i: Acta Oto-Laryngologica. - : Informa UK Limited. - 0001-6489 .- 1651-2251. ; 108:5-6, s. 345-354
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Tidskriftsartikel (refereegranskat)abstract
- Twelve subjects with bilateral vestibular loss, with a mean age of 27 years (18-49) were studied. The loss was based on symptoms of oscillopsia and ice-water caloric tests. Nine subjects were evaluated by low-frequency sinusoidal harmonic acceleration (SHA) rotatory tests (0.01-0.32 Hz), and 3 subjects with high broad-frequency band rotatory tests (0.25-3.25 Hz). During alertness tests (darkness) all subjects had absent or very low gains. When tested with a stationary light in the middle of the swing, the SHA tests showed perfect compensatory eye movements with gains of 1 and phases of approximately 0 degrees. In the broad-frequency test, the gain was near 1 below 1 Hz, decreasing rapidly at higher frequencies. In imaginary stationary target tests (darkness), the gain was enhanced to 'normal' values (0.5) with a phase lead in the low-frequency range (SHA). This could not be replicated in the high-frequency tests. Testing with stationary acoustic guidance (darkness), further enhanced the gain in the SHA tests. A small increase of gain could also be found in the high-frequency tests. Compensatory eye movements, when tested in low-frequency rotatory tests (less than 1 Hz), are to a large extent influenced by non-vestibular mechanisms. By voluntary modifications, normal gains could be produced by patients with 'bilateral vestibular loss'. The phase lead found is proposed to be of central non-vestibular origin. Testing in higher frequency ranges (greater than 1 Hz) could not replicate these findings, thus the broad-frequency band rotatory test should be preferred for adequate vestibular quantification.
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| 11. |
- Möller, Claes, 1950-, et al.
(författare)
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The plasticity of compensatory eye movements in rotatory tests: 1 : the effect of alertness and eye closure
- 1990
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Ingår i: Acta Oto-Laryngologica. - : Informa UK Limited. - 0001-6489 .- 1651-2251. ; 109:1-2, s. 15-24
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Tidskriftsartikel (refereegranskat)abstract
- Fifteen voluntary subjects with a mean age of 26 years (17–39), participated in two rotatory experiments. The rotatory test used was sinusoidal harmonic acceleration (SHA) test at frequencies of 0.01–0.32 Hz. Compensatory eye movements were measured by means of EOG. Experiment A included rotation in darkness during alerting tasks (day 1), rotation in darkness with no tasks (day 2) and rotation in darkness during alerting tasks (day 3). In the altertness tests, the gain varied between 0.5 and 0.77. Phase values decreased with increasing frequency. The alertness results between days 1 and 3 did not differ in gain or phase. The gain of day 2 (no tasks) displayed significantly reduced gain at all frequencies, and a more pronounced decrease in phase than in the alertness tests. Experiment B compared testing with eyes open (day 1) and eyes closed (day 2) during alerting tasks. These tests displayed significantly decreased gain at all frequencies with eyes closed compared with eyes open and with more negative phase at 0.08–0.32 Hz with eyes closed. The results indicate a central effect of the alertness level on compensatory eye movements, and the effect of eye closure might be explained by bio-mechanical and possibly even central effects on the eye movements. In low-frequency testing, as short a test time as possible should be used, and due to different alertness levels, the results should be evaluated with great caution.
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| 12. |
- Möller, Claes, 1950-, et al.
(författare)
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Usher syndrome : an otoneurologic study
- 1989
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Ingår i: The Laryngoscope. - : Wiley. - 0023-852X .- 1531-4995. ; 99:1, s. 73-79
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Tidskriftsartikel (refereegranskat)abstract
- Usher syndrome is an autosomal recessive disorder characterized by severe hearing loss or deafness and retinitis pigmentosa. Eleven families with 25 affected members were studied. The test battery included genetic studies, clinical examination, audiological, ophthalmologic, and otoneurological tests, and magnetic resonance imaging. Sixteen affected persons had profound hearing loss or were considered anacusic, with absent bilateral vestibular responses. These patients had varying degrees of retinitis pigmentosa. These 16 patients were considered to have type I Usher syndrome. Nine persons were diagnosed as Usher type II with a moderate to profound hearing loss, normal vestibular function, and retinitis pigmentosa of varying degree. Magnetic resonance imaging was normal in all cases. Otoneurological tests indicated no central nervous system disturbances. The conclusion is that hearing loss and balance problems in Usher syndrome are due to inner ear damage with no evidence of central nervous system disturbances. Furthermore, the ataxia seen in Usher type I is due to a combination of retinitis pigmentosa and bilateral peripheral vestibular deficiency.
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| 13. |
- Möller, Claes, 1950-, et al.
(författare)
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Usher's syndrome
- 1988
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Ingår i: Vertigo, nausea, tinnitus and hypoacusia in metabolic disorders. - Amsterdam : Elsevier. - 9780444810243 ; , s. 319-326
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 14. |
- Tham, Richard, et al.
(författare)
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Vestibulotoxicity of organic solvents
- 1991
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Ingår i: Fourth international conference on combined effect of environmental factors. - : Johns Hopkins University. ; , s. 101-105
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Konferensbidrag (refereegranskat)
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| 15. |
- Vrethem, Magnus, et al.
(författare)
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Correlation between dynamic posturography, clinical investigation, and neurography in patients with polyneuropathy
- 1991
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Ingår i: Journal for Oto-Rhino-Laryngology. - : S. Karger AG. - 0301-1569 .- 1423-0275. ; 53:5, s. 294-298
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Tidskriftsartikel (refereegranskat)abstract
- Dynamic posturography (PG) is a new objective method to study functional performance in diseases affecting balance. It measures muscle response latencies and sway angles to standardized alterations of a moveable platform and moveable surroundings. Twenty-eight patients with polyneuropathy (PN) were studied by clinical investigation, vibrametry, neurography, and dynamic PG. The results of dynamic PG and vibrametry were compared with those of 29 healthy controls. In the patients with PN, clinical scores correlated to the latencies of the muscle response when the platform was suddenly moved forward, and to equilibrium performance (sway angles) in dynamic PG test conditions with eyes closed and the platform either stable or ‘sway-referenced’. That is, the platform moves in response to the patient’s anterior-posterior sway, creating a disturbed proprioceptive input to the brain. Clinical scores also correlated to the equilibrium performance when both platform and surroundings were sway-referenced. In conclusion dynamic PG, in addition to clinical investigations and neurophysiology, is a valuable and objective method for estimating the equilibrium performance in patients with PN.
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| 17. |
- Ödkvist, Lars M., et al.
(författare)
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Findings in olivopontocerebellar degeneration
- 1988
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Ingår i: Vertigo, nausea, tinnitus, and hypoacusia in metabolic disorders. - 9780444810243 ; , s. 327-331
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Konferensbidrag (refereegranskat)
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| 18. |
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| 19. |
- Ödkvist, Lars, 1935-, et al.
(författare)
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Neurootology in neck trauma patients
- 2004
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Ingår i: Bárány Society XXIII International Congress,2004. ; , s. 156-156
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 20. |
- Ödkvist, Lars, et al.
(författare)
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Otolithic tests in Menière’s disease
- 1995
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Ingår i: Ménièr's Disease, 1995. - 8798242253 ; , s. 259-265
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 21. |
- Ödkvist, Lars, et al.
(författare)
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The subjective horizontal in eccentric rotation influenced by peripheral vestibular lesion
- 1996
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Ingår i: Acta Oto-Laryngologica. - : Informa Healthcare. - 0001-6489 .- 1651-2251. ; 116:2, s. 181-184
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Tidskriftsartikel (refereegranskat)abstract
- Peripheral vestibular equilibrium disorders may originate in various parts of the labyrinth or the vestibular nerve. Traditionally, the function of the lateral semicircular canals has been assessed with caloric irrigation, and sometimes falsely been interpreted as a vestibular nerve lesion. the vertical semicircular canals are not easily assessed. Caloric testing with the head in different positions is not very helpful, but the canals may pairwise be tested using specific rotational techniques. Often the otolithic organs, capable of detecting linear acceleration forces, are forgotten as a source of vertigo and dizziness. We have implemented horizontal rotatory testing with the subject seated eccentrically facing the direction of rotation as a means of assessing otolithic function. the subject experiences a lateral tilt and is instructed in darkness to put a short light bar in the position he thinks a water surface would have, which is identical to his perceived tilt. in 39 normal subjects, a theoretical tilt of 24° was estimated as approximately 19.5°, and the standard deviation was 6°. A side difference index was proposed to be normal if below 25%. the preliminary findings in a few patients with known labyrinthine lesions are presented. We propose that otolithic as well as lateral semicircular canal functions are useful to monitor in patients with suspected peripheral equilibrium disorders.
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