| 1. |
- Azevedo, Flavio, et al.
(författare)
-
Social and moral psychology of COVID-19 across 69 countries
- 2023
-
Ingår i: Scientific Data. - : NATURE PORTFOLIO. - 2052-4463. ; 10:1
-
Tidskriftsartikel (refereegranskat)abstract
- The COVID-19 pandemic has affected all domains of human life, including the economic and social fabric of societies. One of the central strategies for managing public health throughout the pandemic has been through persuasive messaging and collective behaviour change. To help scholars better understand the social and moral psychology behind public health behaviour, we present a dataset comprising of 51,404 individuals from 69 countries. This dataset was collected for the International Collaboration on Social & Moral Psychology of COVID-19 project (ICSMP COVID-19). This social science survey invited participants around the world to complete a series of moral and psychological measures and public health attitudes about COVID-19 during an early phase of the COVID-19 pandemic (between April and June 2020). The survey included seven broad categories of questions: COVID-19 beliefs and compliance behaviours; identity and social attitudes; ideology; health and well-being; moral beliefs and motivation; personality traits; and demographic variables. We report both raw and cleaned data, along with all survey materials, data visualisations, and psychometric evaluations of key variables.
|
|
| 2. |
- Van Bavel, Jay J., et al.
(författare)
-
National identity predicts public health support during a global pandemic
- 2022
-
Ingår i: Nature Communications. - : Nature Portfolio. - 2041-1723. ; 13:1
-
Tidskriftsartikel (refereegranskat)abstract
- Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported greater engagement in public health behaviours and support for public health policies in the context of the pandemic. Changing collective behaviour and supporting non-pharmaceutical interventions is an important component in mitigating virus transmission during a pandemic. In a large international collaboration (Study 1, N = 49,968 across 67 countries), we investigated self-reported factors associated with public health behaviours (e.g., spatial distancing and stricter hygiene) and endorsed public policy interventions (e.g., closing bars and restaurants) during the early stage of the COVID-19 pandemic (April-May 2020). Respondents who reported identifying more strongly with their nation consistently reported greater engagement in public health behaviours and support for public health policies. Results were similar for representative and non-representative national samples. Study 2 (N = 42 countries) conceptually replicated the central finding using aggregate indices of national identity (obtained using the World Values Survey) and a measure of actual behaviour change during the pandemic (obtained from Google mobility reports). Higher levels of national identification prior to the pandemic predicted lower mobility during the early stage of the pandemic (r = -0.40). We discuss the potential implications of links between national identity, leadership, and public health for managing COVID-19 and future pandemics.
|
|
| 3. |
- Wang, Zhaoming, et al.
(författare)
-
Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
- 2014
-
Ingår i: Human Molecular Genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 23:24, s. 6616-6633
-
Tidskriftsartikel (refereegranskat)abstract
- Genome-wide association studies (GWAS) have mapped risk alleles for at least 10 distinct cancers to a small region of 63 000 bp on chromosome 5p15.33. This region harbors the TERT and CLPTM1L genes; the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play a role in apoptosis. To investigate further the genetic architecture of common susceptibility alleles in this region, we conducted an agnostic subset-based meta-analysis (association analysis based on subsets) across six distinct cancers in 34 248 cases and 45 036 controls. Based on sequential conditional analysis, we identified as many as six independent risk loci marked by common single-nucleotide polymorphisms: five in the TERT gene (Region 1: rs7726159, P = 2.10 × 10(-39); Region 3: rs2853677, P = 3.30 × 10(-36) and PConditional = 2.36 × 10(-8); Region 4: rs2736098, P = 3.87 × 10(-12) and PConditional = 5.19 × 10(-6), Region 5: rs13172201, P = 0.041 and PConditional = 2.04 × 10(-6); and Region 6: rs10069690, P = 7.49 × 10(-15) and PConditional = 5.35 × 10(-7)) and one in the neighboring CLPTM1L gene (Region 2: rs451360; P = 1.90 × 10(-18) and PConditional = 7.06 × 10(-16)). Between three and five cancers mapped to each independent locus with both risk-enhancing and protective effects. Allele-specific effects on DNA methylation were seen for a subset of risk loci, indicating that methylation and subsequent effects on gene expression may contribute to the biology of risk variants on 5p15.33. Our results provide strong support for extensive pleiotropy across this region of 5p15.33, to an extent not previously observed in other cancer susceptibility loci.
|
|
| 4. |
|
|
| 5. |
|
|
| 6. |
- Ahlgren, Per, 1960-, et al.
(författare)
-
A bibliometric analysis of battery research with the BATTERY 2030+ roadmap as point of departure
- 2022
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- In this bibliometric study, we analyze the six battery research subfields identified in the BATTERY 2030+ roadmap: Battery Interface Genome, Materials Acceleration Platform, Recyclability, Smart functionalities: Self-healing, Smart functionalities: Sensing, and Manufacturability. In addition, we analyze the entire research field related to BATTERY 2030+ as a whole, using two operationalizations. We (a) evaluate the European standing in the subfields/the BATTERY 2030+ field in comparison to the rest of the world, and (b) identify strongholds of the subfields/the BATTERY 2030+ field across Europe. For each subfield and the field as a whole, we used seed articles, i.e. articles listed in the BATTERY 2030+ roadmap or cited by such articles, in order to generate additional, similar articles located in an algorithmically obtained classification system. The output of the analysis is publication volumes, field normalized citation impact values with comparisons between country/country aggregates and between organizations, co-publishing networks between countries and organizations, and keyword co-occurrence networks. For the results related to (a), the performance of EU & associated (countries) is similar to China and the aggregate Japan-South Korea-Singapore and well below North America regarding citation impact and with respect to the field as a whole. Exceptions are, however, the subfields Battery Interface Genome and Recyclability. For the results related to (b), there is a large variability in the EU & associated organizations regarding volume in the different subfields. For citation impact, examples of high-performing EU & associated organizations are ETH Zurich and Max Planck Society for the Advancement of Science.
|
|
| 7. |
- Ahlgren, Per, 1960-, et al.
(författare)
-
BATTERY 2030+ and its Research Roadmap : A Bibliometric Analysis.
- 2023
-
Ingår i: ChemSusChem. - : Wiley. - 1864-5631 .- 1864-564X. ; 16:21
-
Tidskriftsartikel (refereegranskat)abstract
- In this bibliometric study, we analyze two of the six battery research subfields identified in the BATTERY 2030+ roadmap: Materials Acceleration Platform and Smart functionalities: Sensing. In addition, we analyze the entire research field related to BATTERY 2030+ as a whole. We (a) evaluate the European standing in the two subfields/the BATTERY 2030+ field in comparison to the rest of the world, and (b) identify strongholds of the two subfields/the BATTERY 2030+ field across Europe. For each subfield and the field as a whole, we used seed articles, i. e. articles listed in the BATTERY 2030+ roadmap or cited by such articles, in order to generate additional, similar articles located in an algorithmically obtained classification system. The output of the analysis is publication volumes, field normalized citation impact values with comparisons between country/country aggregates and between organizations, co-publishing networks between countries and organizations, and keyword co-occurrence networks.
|
|
| 8. |
- Amici, Julia, et al.
(författare)
-
A Roadmap for Transforming Research to Invent the Batteries of the Future Designed within the European Large Scale Research Initiative BATTERY 2030
- 2022
-
Ingår i: Advanced Energy Materials. - : John Wiley & Sons. - 1614-6832 .- 1614-6840. ; 12:17
-
Forskningsöversikt (refereegranskat)abstract
- This roadmap presents the transformational research ideas proposed by "BATTERY 2030+," the European large-scale research initiative for future battery chemistries. A "chemistry-neutral" roadmap to advance battery research, particularly at low technology readiness levels, is outlined, with a time horizon of more than ten years. The roadmap is centered around six themes: 1) accelerated materials discovery platform, 2) battery interface genome, with the integration of smart functionalities such as 3) sensing and 4) self-healing processes. Beyond chemistry related aspects also include crosscutting research regarding 5) manufacturability and 6) recyclability. This roadmap should be seen as an enabling complement to the global battery roadmaps which focus on expected ultrahigh battery performance, especially for the future of transport. Batteries are used in many applications and are considered to be one technology necessary to reach the climate goals. Currently the market is dominated by lithium-ion batteries, which perform well, but despite new generations coming in the near future, they will soon approach their performance limits. Without major breakthroughs, battery performance and production requirements will not be sufficient to enable the building of a climate-neutral society. Through this "chemistry neutral" approach a generic toolbox transforming the way batteries are developed, designed and manufactured, will be created.
|
|
| 9. |
- Amundadottir, Laufey, et al.
(författare)
-
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.
- 2009
-
Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 41, s. 986-990
-
Tidskriftsartikel (refereegranskat)abstract
- We conducted a two-stage genome-wide association study of pancreatic cancer, a cancer with one of the lowest survival rates worldwide. We genotyped 558,542 SNPs in 1,896 individuals with pancreatic cancer and 1,939 controls drawn from 12 prospective cohorts plus one hospital-based case-control study. We conducted a combined analysis of these groups plus an additional 2,457 affected individuals and 2,654 controls from eight case-control studies, adjusting for study, sex, ancestry and five principal components. We identified an association between a locus on 9q34 and pancreatic cancer marked by the SNP rs505922 (combined P = 5.37 x 10(-8); multiplicative per-allele odds ratio 1.20; 95% confidence interval 1.12-1.28). This SNP maps to the first intron of the ABO blood group gene. Our results are consistent with earlier epidemiologic evidence suggesting that people with blood group O may have a lower risk of pancreatic cancer than those with groups A or B.
|
|
| 10. |
- Andersson, Stefan S., et al.
(författare)
-
Origin of the high-temperature Olserum-Djupedal REE-phosphate mineralisation, SE Sweden : A unique contact metamorphic-hydrothermal system
- 2018
-
Ingår i: Ore Geology Reviews. - : Elsevier BV. - 0169-1368 .- 1872-7360. ; 101, s. 740-764
-
Tidskriftsartikel (refereegranskat)abstract
- The Swedish part of the Fennoscandian Shield hosts a variety of rare earth element (REE) deposits, including magmatic to magmatic-hydrothermal types. This paper focuses on the origin of the Olserum-Djupedal REEphosphate mineralisation located in the sparsely studied Vastervik region, SE Sweden. Here, mineralisation occurs in three main areas, Olserum, Djupedal and Bersummen. Primary hydrothermal REE mineralisation formed at high temperatures (about 600 degrees C), leading to precipitation of monazite-(Ce), xenotime-(Y), fluor apatite and minor (Y,REE,U,Fe)-(Nb,Ta)-oxides in veins and vein zones dominated by biotite, amphibole, magnetite and quartz. The veins are hosted primarily by metasedimentary rocks present close to, or within, the contact aureole of a local 1.8 Ga ferroan alkali feldspar granite pluton, but also occur within in the chemically most primitive granite in the outermost part of that pluton. In the Djupedal area, REE-mineralised metasedimentary bodies are extensively migmatised, with migmatisation post-dating the main stage of mineralisation. In the Olserum and Bersummen areas, the REE-bearing veins are cross-cut by abundant pegmatitic to granitic dykes. The field-relationships demonstrate a-protracted magmatic evolution of the granitic,pluton and a clear spatial and temporal relationship of the REE mineralisation to the granite. The major and trace element chemistry of ore-associated biotite and magnetite support genetic links between all mineralised areas. Biotite mineral chemistry data further demonstrate a distinct chemical trend from meta sediment-hosted ore-associated biotite distal to the major contact of the granite to the biotite in the granite hosted veins. This trend is characterised by a systematic decrease in Mg and Na and a coupled increase in Fe and Ti with proximity to the granite-hosted veins. The halogen compositions of ore-associated biotite indicate elevated contents of HCl and HF in the primary REE mineralising fluid. Calculated log(f(HF)/f(HCL)) values in the Olserum area suggest a constant ratio of about -1 at temperatures of 650-550 degrees C during the evolution of the primary hydrothermal system. In the Djupedal and Bersummen areas, the fluid locally equilibrated at lower log (f(HF)/f(HCl)) values down to -2. High Na contents in ore-associated biotite and amphibole, and the abundance of primary ore-associated biotite indicate a K- and Na-rich character of the primary REE mineralising fluid and suggest initial high-temperature K-Na metasomatism. With subsequent cooling of the system, the fluid evolved locally to more Ca-rich compositions as indicated by the presence of the Ca-rich minerals allanite-(Ce) and uvitic tourmaline and by the significant calcic alteration of monazite-(Ce). The later Ca-rich stages were probably coeval with low to medium-high temperature (200-500 degrees C) Na-Ca metasomatism variably affecting the granite and the wall rocks, producing distinct white quartz-plagioclase rocks. All observations and data lead us to discard the prevailing model that the REE mineralisation in the Olserum-Djupedal district represents assimilated and remobilised former heavy mineral-rich beds. Instead, we propose that the primary REE mineralisation formed by granite-derived fluids enriched in REE and P that were expelled early during the evolution of a local granitic pluton. The REE mineralisation developed primarily in the contact aureole of this granite and represents the product of a high temperature contact metamorphic-hydrothermal mineralising system. The REE mineralisation probably formed synchronously with K-Na and subsequent Na-Ca metasomatism affecting the granite and the wall rocks. The later Na-Ca metasomatic stage is probably related to a regional Na +/- Ca metasomatic and associated U +/- REE mineralising system operating concurrently with granitic magmatism at c. 1.8 Ga in the Vastervik region. This highlights the potential for discovering hitherto unknown REE deposits and for the reappraisal of already known deposits in this part of the Fennoscandian Shield.
|
|
| 11. |
|
|
| 12. |
- Anheden, Marie, et al.
(författare)
-
Value chain for production of bio-oil from kraft lignin for use as bio-jet fuel
- 2017
-
Ingår i: The 7th Nordic Wood Biorefinery Conference held in Stockholm, Sweden, 28-30 Mar. 2017. - Stockholm : RISE Bioekonomi. - 9789186018207 ; , s. 104-109
-
Konferensbidrag (refereegranskat)abstract
- The LignoJet project aimed to achieve an intermediate lignin-oil product miscible with fossil feedstock and with a significantly reduced oxygen content. A technical concept for production has been studied that involves combined catalysed depolymerisation and hydrodeoxygenation, so called hydrogenolytic depolymerisation, of kraft lignin. Kraft lignin was separated through membrane ultrafiltration from softwood and eucalyptus black liquor followed by precipitation through LignoBoost technology. A difference in lignin properties was observed between ultrafiltration of softwood and eucalyptus black liquor through 15 and 150kDa ceramic membranes. Lignin-oils with similar oxygen content were produced regardless of origin and fractionation technique. A lignin-oil with favourable properties as precursor for refinery integration for jet fuel production as produced in small-scale batch experiments using nickel-based catalyst. Stable pumpable oils with melting point of less than 25-50 deg C and with 20-30% lower oxygen content and aromatic content were obtained that would be suitable as jet fuel precursors. The estimated production cost was found to be competitive with that of other liquid biofuels, while additional revenues could potentially be achieved by also producing chemical and materials from suitable fractions of the lignin-oil.
|
|
| 13. |
- Berg, Cecilia, et al.
(författare)
-
Developmental exposure to fluoxetine modulates the serotonin system in hypothalamus
- 2013
-
Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 8:1
-
Tidskriftsartikel (refereegranskat)abstract
- The selective serotonin reuptake inhibitor (SSRI) fluoxetine (FLU, Prozac®) is commonly prescribed for depression in pregnant women. This results in SSRI exposure of the developing fetus. However, there are knowledge gaps regarding the impact of SSRI exposure during development. Given the role of serotonin in brain development and its cross-talk with sex hormone function, we investigated effects of developmental exposure to pharmacologically relevant concentrations of FLU (3 and 30 nM (measured)) on brain neurotransmitter levels, gonadal differentiation, aromatase activity in brain and gonads, and the thyroid system, using the Xenopus tropicalis model. Tadpoles were chronically exposed (8 weeks) until metamorphosis. At metamorphosis brains were cryosectioned and levels of serotonin, dopamine, norepinephrine, and their metabolites 5-hydroxyindoleacetic acid, 3,4-dihydroxyphenylacetic acid, and homovanillic acid were measured in discrete regions (telencephalon, hypothalamus and the reticular formation) of the cryosections using high-performance liquid chromatography. Exposure to 30 nM FLU increased the concentration of 5-hydroxyindoleacetic acid in hypothalamus compared with controls. FLU exposure did not affect survival, time to metamorphosis, thyroid histology, gonadal sex differentiation, or aromatase activity implying that the effect on the serotonergic neurotransmitter system in the hypothalamus region was specific. The FLU concentration that impacted the serotonin system is lower than the concentration measured in umbilical cord serum, suggesting that the serotonin system of the developing brain is highly sensitive to in utero exposure to FLU. To our knowledge this is the first study showing effects of developmental FLU exposure on brain neurochemistry. Given that SSRIs are present in the aquatic environment the current results warrant further investigation into the neurobehavioral effects of SSRIs in aquatic wildlife.
|
|
| 14. |
- Berg, Daniel, 1971, et al.
(författare)
-
Duo Granmo-Berg
- 2017
-
Ingår i: Marten Recordings, Mölndal, Sweden.
-
Konstnärligt arbete (övrigt vetenskapligt/konstnärligt)abstract
- This Swedish violinist and marimba a duo is confidently carving a genre of their own. Granmo-Berg’s years of experience and passion shines through every moment of this High-End live recording. With only two microphones, the sound is natural, dynamic and lively. The music is an eclectic mixture of Classical, Percussion and Latin composed by Bach, Vivaldi and Béla Bartók. It also includes works by well known Swedish composers, and songs written by themselves. Recorded by renowned musician and producer Peter Axelsson at Marten Recordings state-of-the-art studio.
|
|
| 15. |
- Berg, Daniel, 1971, et al.
(författare)
-
Sinnenas musik : En exkursion i sex satser
- 2023
-
Bok (övrigt vetenskapligt/konstnärligt)abstract
- Vad händer när musik möter människans olika sinnen? Hur påverkas vi av musiken vi hör, och vad kan vi med sinnenas hjälp lära oss? Hur låter champagne, hur doftar Vivaldi och vad kan klanger ge för aromatiska associationer? ”Sinnenas musik” är en utforskning av musikens betydelse för våra sinnen och hur våra sinnen korsbefruktar varandra. Att musik har betydelse för både kropp och själ har nog de flesta personlig erfarenhet av. Inte minst hjärnans olika funktioner påverkas av tonkonst, som motivation, uppmärksamhet, känslor, minne och språkförmåga. Ny forskning visar också att kultur i olika former kan vara skyddande mot bland annat Alzheimers sjukdom. Så vare sig du lever i allegrissimo eller i ett lugnare andante, i dur eller moll, gillar ensemblespel eller föredrar solouppträdanden, påverkas alla dina sinnen av musik kanske också på ett sätt som du inte är helt medveten om. Boken har tillkommit efter en seminarieserie på Jonsereds herrgård vid Göteborgs universitet. Redaktörer är Anna Falkenland och Lena Ulrika Rudeke. Textförfattaren Eva Lundgren är redaktör och journalist. Förord av Catharina Dyrssen, professor emerita i arkitektur och designmetodik. Länk till musik med Duo Granmo-Berg – Tobias Granmo, violinist och lektor i kammarmusik, och Daniel Berg, slagverkare, kompositör och professor i musikalisk gestaltning. Boken avslutas med en ackompanjerande bildsvit för fortsatt utforskande av sinnenas korsbefruktning.
|
|
| 16. |
- Berg, Monika, 1979-, et al.
(författare)
-
Building Institutional Trust Through Service Experiences : Private Versus Public Provision Matter
- 2020
-
Ingår i: Journal of public administration research and theory. - : Oxford University Press. - 1053-1858 .- 1477-9803. ; 30:2, s. 290-306
-
Tidskriftsartikel (refereegranskat)abstract
- Welfare service experiences are known to shape citizens' trust in public institutions and their sup-port of the welfare state. But, there is poor understanding of how this relationship is shaped in systems of mixed provision, that is, welfare states that use public in-house as well as contracted private providers for publically funded services. Drawing on the notion of system trust this article provides a theoretical account of how mixed-provision welfare systems condition the relationship between service experience and trust, affecting the legitimacy of the state. Utilizing a random-ized vignette experiment with participants in a general citizen survey in Sweden, we investigate whether it matters for the formation of institutional trust if the welfare service is provided by a public or third-party private provider. The main result show that the spillover of trust from positive service experiences with the provider to trust in public institutions is higher in cases of public ser-vice provision. Thus, the possibility of using welfare services to build trust in the welfare system seems to be greater when public provision is used.
|
|
| 17. |
- Berg, Monika, 1979-, et al.
(författare)
-
Trust and safety in the segregated city : contextualizing the relationship between institutional trust, crime-related insecurity and generalized trust
- 2016
-
Ingår i: Scandinavian Political Studies. - : Wiley-Blackwell. - 0080-6757 .- 1467-9477. ; 39:4, s. 458-481
-
Tidskriftsartikel (refereegranskat)abstract
- Trust is a crucial asset for any society, and the quest to generate and uphold trust is as crucial as ever. Several contemporary societal developments are proposed as being particularly challenging for upholding and restoring the levels of trust in society, including increasing ethnic diversity, rising inequality and the related geographical segregation. It has been convincingly argued that democratic institutions may generate trust by neutralizing some of these effects. This article explores how the mechanisms of trust differ in segregated, disadvantaged neighbourhoods as opposed to the surrounding general society. The empirical material consists of individual-level data from a segregated neighbourhood (Vivalla) in a medium-sized city in Sweden (Örebro), with a random sample from the population of the city (the Vivalla area excluded) as the comparison reference point, representing the general society. In the article we introduce perceived safety as an important mediator between trust in legal and government institutions and generalized trust, through which the differing mechanisms become evident. In the disadvantaged neighbourhood, we show that trust in government institutions has the function of primarily decreasing crime-related insecurity, which in its turn affects generalized trust. Thus, the relationship is indirect. In the city population, the effect instead goes directly from trust in government institutions to generalized trust. The results suggest that the potentials of different means to build and restore trust are dependent on local context.
|
|
| 18. |
- Berg, Tracy J., et al.
(författare)
-
The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2
- 2021
-
Ingår i: Cancer Research. - : American Association For Cancer Research (AACR). - 0008-5472 .- 1538-7445. ; 81:8, s. 2101-2115
-
Tidskriftsartikel (refereegranskat)abstract
- The tumor microenvironment plays an essential role in supporting glioma stemness and radioresistance. Following radiotherapy, recurrent gliomas form in an irradiated microenvironment. Here we report that astrocytes, when pre-irradiated, increase stemness and survival of cocultured glioma cells. Tumor-naive brains increased reactive astrocytes in response to radiation, and mice subjected to radiation prior to implantation of glioma cells developed more aggressive tumors. Extracellular matrix derived from irradiated astrocytes were found to be a major driver of this phenotype and astrocyte-derived transglutaminase 2 (TGM2) was identified as a promoter of glioma stemness and radioresistance. TGM2 levels increased after radiation in vivo and in recurrent human glioma, and TGM2 inhibitors abrogated glioma stemness and survival. These data suggest that irradiation of the brain results in the formation of a tumor-supportive microenvironment. Therapeutic targeting of radiation-induced, astrocyte-derived extracellular matrix proteins may enhance the efficacy of standard-of-care radiotherapy by reducing stemness in glioma. Significance: These findings presented here indicate that radiotherapy can result in a tumor-supportive microenvironment, the targeting of which may be necessary to overcome tumor cell therapeutic resistance and recurrence.
|
|
| 19. |
- Carrington, T., et al.
(författare)
-
The average professional : On the selection and socialisation of auditors
- 2023
-
Ingår i: Auditing Transformation: Regulation, Digitalisation and Sustainability. - : Taylor and Francis. - 9781003411390 - 9781032533032 ; , s. 275-293
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- By collecting and analysing survey data from newly employed audit assistants at the largest accounting firms in Sweden, this chapter aims to analyse key aspects of becoming an auditor. The study investigates the characteristics of these audit assistants and to what extent their opinions coincide with the opinions of other highly educated citizens. It also investigates to what extent four value commitments of the new recruits coincide with these of senior auditors. The results show that the ones recruited today are more diverse than their older peers with respect to educational, socio-economical, and geographical backgrounds. While sharing high confidence in the universities, the legal system, and the police, the audit recruits' opinions (i.e. trust in societal institutions like the media) deviate from other citizens with higher education. The similar opinions related to auditing (e.g. professional and client commitments) indicate that the newly recruited auditors seem to already closely reflect the identity of authorised and approved auditors when being employed. They also believe that the reason for their being hired is more related to ‘soft’ skills than to ‘hard’ accounting and auditing knowledge.
|
|
| 20. |
- Carrington, Thomas, 1974-, et al.
(författare)
-
The average professional : On the selection and socialisation of auditors
- 2023
-
Ingår i: Auditing Transformation. - : Routledge. - 9781003411390 - 9781032533032 ; , s. 275-293
-
Bokkapitel (refereegranskat)abstract
- By collecting and analysing survey data from newly employed audit assistants at the largest accounting firms in Sweden, this chapter aims to analyse key aspects of becoming an auditor. The study investigates the characteristics of these audit assistants and to what extent their opinions coincide with the opinions of other highly educated citizens. It also investigates to what extent four value commitments of the new recruits coincide with these of senior auditors. The results show that the ones recruited today are more diverse than their older peers with respect to educational, socio-economical, and geographical backgrounds. While sharing high confidence in the universities, the legal system, and the police, the audit recruits' opinions (i.e. trust in societal institutions like the media) deviate from other citizens with higher education. The similar opinions related to auditing (e.g. professional and client commitments) indicate that the newly recruited auditors seem to already closely reflect the identity of authorised and approved auditors when being employed. They also believe that the reason for their being hired is more related to ‘soft’ skills than to ‘hard’ accounting and auditing knowledge.
|
|
| 21. |
- Collins, Ruairi, et al.
(författare)
-
Biochemical discrimination between selenium and sulfur 1 : a single residue provides selenium specificity to human selenocysteine lyase
- 2012
-
Ingår i: PLoS One. - Stockholm : Karolinska Institutet, Dept of Medical Biochemistry and Biophysics. - 1932-6203.
-
Tidskriftsartikel (refereegranskat)abstract
- Selenium and sulfur are two closely related basic elements utilized in nature for a vast array of biochemical reactions. While toxic at higher concentrations, selenium is an essential trace element incorporated into selenoproteins as selenocysteine (Sec), the selenium analogue of cysteine (Cys). Sec lyases (SCLs) and Cys desulfurases (CDs) catalyze the removal of selenium or sulfur from Sec or Cys and generally act on both substrates. In contrast, human SCL (hSCL) is specific for Sec although the only difference between Sec and Cys is the identity of a single atom. The chemical basis of this selenium-over-sulfur discrimination is not understood. Here we describe the X-ray crystal structure of hSCL and identify Asp146 as the key residue that provides the Sec specificity. A D146K variant resulted in loss of Sec specificity and appearance of CD activity. A dynamic active site segment also provides the structural prerequisites for direct product delivery of selenide produced by Sec cleavage, thus avoiding release of reactive selenide species into the cell. We thus here define a molecular determinant for enzymatic specificity discrimination between a single selenium versus sulfur atom, elements with very similar chemical properties. Our findings thus provide molecular insights into a key level of control in human selenium and selenoprotein turnover and metabolism.
|
|
| 22. |
- Diaz de Grenu, Borja, et al.
(författare)
-
Fluorescent Discrimination between Traces of Chemical Warfare Agents and Their Mimics
- 2014
-
Ingår i: Journal of the American Chemical Society. - : American Chemical Society (ACS). - 0002-7863 .- 1520-5126. ; 136:11, s. 4125-4128
-
Tidskriftsartikel (refereegranskat)abstract
- An array of fluorogenic probes is able to discriminate between nerve agents, sarin, soman, tabun, VX and their mimics, in water or organic solvent, by qualitative fluorescence patterns and quantitative multivariate analysis, thus making the system suitable for the in-the-field detection of traces of chemical warfare agents as well as to differentiate between the real nerve agents and other related compounds.
|
|
| 23. |
- Edström, Kristina, Professor, 1958-
(författare)
-
Battery 2030+ Roadmap
- 2020
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Climate change is the biggest challenge facing the world today. Europe is committed to achieving a climate-neutral society by 2050, as stated in the European Green Deal.1 The transition towards a climate-neutral Europe requires fundamental changes in the way we generate and use energy. If batteries can be made simultaneously more sustainable, safe, ultrahigh performing, and affordable, they will be true enablers, “accelerating the shift towards sustainable and smart mobility; supplying clean, affordable and secure energy; and mobilizing industry for a clean and circular economy” - all of which are important elements of the UN Sustainable Development Goals.In other words, batteries are a key technology for battling carbon dioxide emissions from the transport, power, and industry sectors. However, to reach our sustainability goals, batteries must exhibit ultra-high performance beyond their capabilities today. Ultra-high performance includes energy and power performance approaching theoretical limits, outstanding lifetime and reliability, and enhanced safety and environmental sustainability. Furthermore, to be commercially successful, these batteries must support scalability that enables cost-effective large-scale production.BATTERY 2030+, is the large-scale, long-term European research initiative with the vision of inventing the sustainable batteries of the future, to enable Europe to reach the goals envisaged in the European Green Deal. BATTERY 2030+ is at the heart of a green and connected society.BATTERY 2030+ will contribute to create a vibrant battery research and development (R&D) community in Europe, focusing on long-term research that will continuously feed new knowledge and technologies throughout the value chain, resulting in new products and innovations. In addition, the initiative will attract talent from across Europe and contribute to ensure access to competences needed for ongoing societal transformation.The BATTERY 2030+ aims are:• to invent ultra-high performance batteries that are safe, affordable, and sustainable, witha long lifetime.• to provide new tools and breakthrough technologies to the European battery industrythroughout the value chain.• to enable long-term European leadership in both existing markets (e.g., transport andstationary storage) and future emerging sectors (e.g., robotics, aerospace, medical devices, and Internet of things)With this roadmap, BATTERY 2030+ advocates research directions based on a chemistry-neutral approach that will allow Europe to reach or even surpass its ambitious battery performance targets set in the European Strategic Energy Technology Plan (SET-Plan)3 and foster innovation throughout the battery value chain.
|
|
| 24. |
- Fehlmann, Tobias, et al.
(författare)
-
Common diseases alter the physiological age-related blood microRNA profile
- 2020
-
Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 11:1
-
Tidskriftsartikel (refereegranskat)abstract
- Aging is a key risk factor for chronic diseases of the elderly. MicroRNAs regulate post-transcriptional gene silencing through base-pair binding on their target mRNAs. We identified nonlinear changes in age-related microRNAs by analyzing whole blood from 1334 healthy individuals. We observed a larger influence of the age as compared to the sex and provide evidence for a shift to the 5’ mature form of miRNAs in healthy aging. The addition of 3059 diseased patients uncovered pan-disease and disease-specific alterations in aging profiles. Disease biomarker sets for all diseases were different between young and old patients. Computational deconvolution of whole-blood miRNAs into blood cell types suggests that cell intrinsic gene expression changes may impart greater significance than cell abundance changes to the whole blood miRNA profile. Altogether, these data provide a foundation for understanding the relationship between healthy aging and disease, and for the development of age-specific disease biomarkers.
|
|
| 25. |
- Forsberg, Tobias, et al.
(författare)
-
Condition Monitoring of Train Ride Stability
- 2007
-
Ingår i: Proceedings of the 7th International Conference on Railway Bogies and Running Gears, BOGIE'07, Budapest, September 3-6, 2007. ; , s. 271-280
-
Konferensbidrag (refereegranskat)
|
|
