1. |
- Bonnett, Brenda, et al.
(författare)
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Lifestyle risk factors for progesterone-related diabetes mellitus in elkhounds - a case-control study
- 2011
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Ingår i: Journal of Small Animal Practice. - : Wiley. - 0022-4510 .- 1748-5827. ; 52, s. 240-245
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Tidskriftsartikel (refereegranskat)abstract
- Methods: Owners of 48 diabetic elkhounds and 58 healthy elkhounds were interviewed by phone concerning lifetime diet and exercise routines. A logistic model was developed to assess the impact of diet and exercise on diabetes diagnosis. The agreement between lifetime owner-perceived body condition score (BCS) and veterinary-perceived BCS at inclusion was estimated in healthy control dogs using the Kappa statistic.Results: The model showed that diabetic dogs had increased odds for having been overweight (before diagnosis) compared with controls (OR=2 center dot 8, 95% confidence interval 1 center dot 1-7 center dot 5, P=0 center dot 034). Although feeding other food than commercial dog feed was associated with diabetes case status, the effect was not significant after BCS was entered into the model. The overall agreement between lifetime owner- and veterinary-perceived BCS at inclusion in the study was 75% and had a Kappa statistic of 0 center dot 16 (P=0 center dot 12).Clinical Significance: This study indicates that a high owner-perceived lifetime BCS is associated with progesterone-related diabetes in elkhounds.
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2. |
- Bremer, Hanna, et al.
(författare)
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Disease patterns and incidence of immune-mediated disease in insured Swedish Nova Scotia Duck Tolling Retrievers
- 2015
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Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 177
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Tidskriftsartikel (refereegranskat)abstract
- In this study, morbidity in insured Nova Scotia Duck Tolling Retriever (NSDTR) dogs from Sweden was investigated and compared with all other breeds and other retriever breeds. In addition to describing common morbidities in NSDTRs, the hypotheses that NSDTRs are predisposed to lymphoma, immune-mediated rheumatic disease (IMRD) and steroid-responsive meningitis-arteritis (SRMA) were tested. Included in the study were 445,336 dogs; of which, 2890 were NSDTRs that had been covered by veterinary insurance from the Agria Insurance Company (Stockholm, Sweden) at some point during the years 1995-2006. Incidences of various health problems were calculated using the number of veterinary visits as the numerator and the exact time at risk as the denominator. Overall, morbidity was higher in NSDTRs compared with all other breeds, but similar compared with other retriever breeds. The most common causes of veterinary visits in NSDTRs were injuries, gastrointestinal disease and locomotor disorders, with NSDTRs at increased risk of these compared with all other breeds. The incidences for IMRD, SRMA and lymphoma were significantly higher in NSDTRs than in all other dog breeds and all other retriever breeds. The study describes morbidity in NSDTRs, and identifies several disorders to which the breed is predisposed.
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3. |
- Egenvall, Agneta, et al.
(författare)
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Insurance data for research in companion animals: benefits and limitations
- 2009
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Ingår i: Acta Veterinaria Scandinavica. - : Springer Science and Business Media LLC. - 0044-605X .- 1751-0147. ; 51
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Forskningsöversikt (refereegranskat)abstract
- The primary aim of this article is to review the use of animal health insurance data in the scientific literature, especially in regard to morbidity or mortality in companion animals and horses. Methods and results were compared among studies on similar health conditions from different nations and years. A further objective was to critically evaluate benefits and limitations of such databases, to suggest ways to maximize their utility and to discuss the future use of animal insurance data for research purposes. Examples of studies on morbidity, mortality and survival estimates in dogs and horses, as well as neoplasia in dogs, are discussed.We conclude that insurance data can and should be used for research purposes in companion animals and horses. Insurance data have been successfully used, e. g. to quantify certain features that may have been hitherto assumed, but unmeasured. Validation of insurance databases is necessary if they are to be used in research. This must include the description of the insured population and an evaluation of the extent to which it represents the source population. Data content and accuracy must be determined over time, including the accuracy/consistency of diagnostic information. Readers must be cautioned as to limitations of the databases and, as always, critically appraise findings and synthesize information with other research. Similar findings from different study designs provide stronger evidence than a sole report. Insurance data can highlight common, expensive and severe conditions that may not be evident from teaching hospital case loads but may be significant burdens on the health of a population.
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4. |
- Egenvall, Agneta, et al.
(författare)
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Integrating databases for research on health and performance in small animals and horses in the Nordic countries
- 2011
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Ingår i: Acta Veterinaria Scandinavica. - 0044-605X .- 1751-0147. ; 53, s. 1-6
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Tidskriftsartikel (refereegranskat)abstract
- Nordic examples of the use of secondary small animal and equine databases include studies based on data from tumour registries, breeding registries, young horse quality contest results, competition data, insurance databases, clinic data, prescription data and hunting ability tests. In spite of this extensive use of secondary databases, integration between databases is less common. The aim of this presentation is to briefly review key papers that exemplify different ways of utilizing data from multiple sources, to highlight the benefits and limitations of the approaches, to discuss key issues/challenges that must be addressed when integrating data and to suggest future directions. Data from pedigree databases have been individually merged with competition data and young horse quality contest data, and true integration has also been done with canine insurance data and with equine clinical data. Data have also been merged on postal code level; i.e. insurance data were merged to a digitized map of Sweden and additional meteorological information added. In addition to all the data quality and validity issues inherent in the use of a single database, additional obstacles arise when combining information from several databases. Loss of individuals due to incorrect or mismatched identifying information can be considerable. If there are any possible biases affecting whether or not individuals can be properly linked, misinformation may result in a further reduction in power. Issues of confidentiality may be more difficult to address across multiple databases. For example, human identity information must be protected, but may be required to ensure valid merging of data. There is a great potential to better address complex issues of health and disease in companion animals and horses by integrating information across existing databases. The challenges outlined in this article should not preclude the ongoing pursuit of this approach.
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5. |
- Egenvall, Agneta, et al.
(författare)
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Morbidity of insured Swedish cats during 1999-2006 by age, breed, sex, and diagnosis
- 2010
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Ingår i: Journal of Feline Medicine and Surgery. - : SAGE Publications. - 1098-612X .- 1532-2750. ; 12, s. 948-959
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the study was to describe patterns of morbidity, as reflected by reimbursed claims for veterinary care among cats covered by a Swedish insurance company during 1999-2006. The annual incidence rates of having at least one veterinary care event were calculated overall and stratified by sex, age, breed, diagnosis and urban/other location. The total rate was 875 (95% Cl 858-892) cats with claims per 10,000 cat-years at risk. The Siamese, Burmese, and the Abyssinians had high rates of claims, compared to the Norwegian Forest cat, the Maine Coon, the European Shorthair and domestic cats. The most common causes for insurance claims were trauma, gastrointestinal and lower urinary tract problems and there was substantial breed, sex and age variation for certain problems. For example, among cats under 9 years of age, the rate for lower urinary tract problems was 2-3 times higher in males than females. (C) 2010 Published by Elsevier Ltd on behalf of ISFM and AAFP.
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6. |
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7. |
- Hanson, Jeanette, et al.
(författare)
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Naturally Occurring Adrenocortical Insufficiency – An Epidemiological Study Based on a Swedish-Insured Dog Population of 525,028 Dogs
- 2016
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Ingår i: Journal of Veterinary Internal Medicine. - : Wiley. - 0891-6640 .- 1939-1676. ; 30, s. 76-84
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Tidskriftsartikel (refereegranskat)abstract
- Background: Naturally occurring adrenocortical insufficiency (NOAI) in dogs is considered an uncommon disease with good prognosis with hormonal replacement treatment. However, there are no epidemiological studies with estimates for the general dog population. Objectives: To investigate the epidemiological characteristics of NOAI in a large population of insured dogs. Animals: Data were derived from 525,028 client-owned dogs insured by a Swedish insurance company representing 2,364,652 dog-years at risk (DYAR) during the period between 1995–2006. Methods: Retrospective cohort study. Incidence rates, prevalences, and relative risks for dogs with NOAI (AI with no previous claim for hypercortisolism), were calculated for the whole dog population, and for subgroups divided by breed and sex. Mortality rates were calculated and compared in dogs with NOAI and the remaining dogs overall. Results: In total 534 dogs were identified with NOAI. The overall incidence was 2.3 cases per 10,000 DYAR. The relative risk of disease was significantly higher in the Portuguese Water Dog, Standard Poodle, Bearded Collie, Cairn Terrier, and Cocker Spaniel compared with other breeds combined. Female dogs overall were at higher risk of developing AI than male dogs (RR 1.85; 95% CI, 1.55–2.22; P < .001). The relative risk of death was 1.9 times higher in dogs with NOAI than in dogs overall. Conclusion and Clinical Importance: The data supports the existence of breed-specific differences in incidence rates of NOAI in dogs.
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9. |
- Hedhammar, Åke, et al.
(författare)
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International and collaborative strategies to enhance genetic health in purebred dogs
- 2011
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Ingår i: Veterinary Journal. - : Elsevier BV. - 1090-0233 .- 1532-2971. ; 189, s. 189-196
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Tidskriftsartikel (refereegranskat)abstract
- Health problems in pedigree dogs have recently been highlighted in the media worldwide and verified internationally by cynological organisations. Collaborative actions are now needed to deal with both existing and future issues. In this article, potential roles for various stakeholders are discussed and the value of national and international platforms for collaborations is stressed. Development of specific strategies for action must be based on criteria of significance, such as severity, prevalence and inheritance, as well as availability of effective preventive measures. Assessment of options should be founded on evidence from appropriate populations-at-risk and consider broader issues, such as demographics and human-animal interactions. Existing data, such as those from insurance statistics and health surveys, should be used as a reference until representative national/international population-level breed-specific data are available. Key issues and challenges, as well as possible strategies to address them, are discussed. (C) 2011 Elsevier Ltd. All rights reserved.
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10. |
- Wang, Shizhi, et al.
(författare)
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Breeding policies and management of pedigree dogs in 15 national kennel clubs
- 2018
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Ingår i: Veterinary Journal. - : Elsevier BV. - 1090-0233 .- 1532-2971. ; 234, s. 130-135
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Tidskriftsartikel (refereegranskat)abstract
- To improve the health and welfare of pedigree dogs, national kennel clubs (KCs) are key players in the governance and regulation of dog breeding. In a survey conducted to investigate differences between KCs in breeding policies and management of pedigree dogs, a questionnaire was completed by 15 KCs from 11 European countries (Austria, Belgium, Denmark, France, Germany, Ireland, Latvia, The Netherlands, Norway, Sweden and the United Kingdom) and four non-European countries (Australia, Mexico, Uruguay and the USA). The most important concerns reported by KCs were exaggerated morphological features and inherited disorders. A wide variety of information, tools and strategies was used to address these issues, with implementation differing across countries and breeds. KCs reported progress in the collection and provision of information related to canine health and welfare. Implementation of advanced breeding tools, such as genetic evaluation and online advisory mating tools, and balanced breeding strategies, endorsed by clubs and breeders, remain challenging and require further development. (C) 2018 Elsevier Ltd. All rights reserved.
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11. |
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12. |
- Öhlund, Malin, et al.
(författare)
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Incidence of Diabetes Mellitus in Insured Swedish Cats in Relation to Age, Breed and Sex
- 2015
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Ingår i: Journal of Veterinary Internal Medicine. - : Wiley. - 0891-6640 .- 1939-1676. ; 29:5, s. 1342-1347
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Tidskriftsartikel (refereegranskat)abstract
- Background: Diabetes mellitus ( DM) is a common endocrinopathy in cats. Most affected cats suffer from a type of diabetes similar to type 2 diabetes in humans. An increasing prevalence has been described in cats, as in humans, related to obesity and other lifestyle factors. Objectives: To describe the incidence of DM in insured Swedish cats and the association of DM with demographic risk factors, such as age, breed and sex. Animals: A cohort of 504,688 individual cats accounting for 1,229,699 cat- years at risk ( CYAR) insured by a Swedish insurance company from 2009 to 2013. Methods: We used reimbursed insurance claims for the diagnosis of DM. Overall incidence rates and incidence rates stratified on year, age, breed, and sex were estimated. Results: The overall incidence rate of DM in the cohort was 11.6 cases ( 95% confidence interval [ CI], 11.0- 12.2) per 10,000 CYAR. Male cats had twice as high incidence rate ( 15.4; 95% CI, 14.4- 16.4) as females ( 7.6; 95% CI, 6.9- 8.3). Domestic cats were at higher risk compared to purebred cats. A significant association with breed was seen, with the Burmese, Russian Blue, Norwegian Forest cat, and Abyssinian breeds at a higher risk compared to other cats. No sex predisposition was found among Burmese cats. Several breeds with a lower risk of DM were identified. Conclusions and clinical importance: Our results verify that the Burmese breed is at increased risk of developing DM. We also identified several previously unreported breeds with increased or decreased risk of DM.
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