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| 4. |
- Bravo, L, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 5. |
- Tabiri, S, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 6. |
- Glasbey, JC, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 11. |
- Milikić, J., et al.
(författare)
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A Pt/MnV2O6 nanocomposite for the borohydride oxidation reaction
- 2021
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Ingår i: Journal of Energy Challenges and Mechanics. - : Elsevier B.V.. - 2056-9386. ; 55, s. 428-436
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Tidskriftsartikel (refereegranskat)abstract
- Problems associated with carbon support corrosion under operating fuel cell conditions require the identification of alternative supports for platinum-based nanosized electrocatalysts. Platinum supported on manganese vanadate (Pt/MnV2O6) was prepared by microwave irradiation method and characterized using X-ray diffraction, Fourier-transform infrared spectroscopy, X-ray photoelectron spectroscopy, scanning electron microscopy with energy dispersive spectroscopy, and transmission electron microscopy. The borohydride oxidation reaction (BOR) on Pt/MnV2O6 was studied in highly alkaline media using voltammetry, chronoamperometry, and electrochemical impedance spectroscopy. BOR electrocatalytic activity of Pt/MnV2O6 was also compared with that of commercial Pt/C (46 wt% Pt) electrocatalyst. The apparent activation energy of BOR at Pt/MnV2O6 was estimated to be 32 kJ mol−1 and the order of reaction to be 0.51, indicating that borohydride hydrolysis proceeds in parallel with its oxidation. Long-term stability of Pt/MnV2O6 under BOR typical conditions was observed. A laboratory-scale direct borohydride fuel cell assembled with a Pt/MnV2O6 anode reached a specific power of 274 W g−1. Experimental results on Pt/MnV2O6 were complemented by DFT calculations, which indicated good adherence of Pt to MnV2O6, beneficial for electrocatalyst stability.
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| 13. |
- Avaz, S., et al.
(författare)
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Graphene based nanosensor for aqueous phase detection of nitroaromatics
- 2017
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Ingår i: RSC Advances. - : Royal Society of Chemistry (RSC). - 2046-2069. ; 7:41, s. 25519-25527
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Tidskriftsartikel (refereegranskat)abstract
- A graphene-based nanosensor was fabricated to selectively detect nitrotriazolone (NTO) molecules with a molecularly imprinted film via simple electrical measurements. Molecularly imprinted polymer comprising chitosan was used as sensitive layer. Gold electrodes for electrical measurements were lithographically fabricated on Si/SiO2 substrate, followed by monolayer graphene transfer and polymeric film coating. Monolayer graphene and molecularly imprinted polymer were characterized by ATR-FTIR, UV-Vis, SEM and Raman spectroscopy. Transfer-length measurements (TLM) indicate that the sensor selectively and linearly responds against aqueous NTO solutions within a wide range of concentration of 0.01-0.1 mg mL(-1) that covers the lowest toxic level of NTO determined by USEPA. This nanosensor with embedded electrodes is re-usable and suitable for field applications, offering real-time electrical measurements unlike current techniques where complex analytics are required.
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- d’Alessandro, N., et al.
(författare)
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RAMCESS 2.x FRAMEWORK - EXPRESSIVE VOICE ANALYSIS FOR REALTIME AND ACCURATE SYNTHESIS OF SINGING
- 2008
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Ingår i: Journal on Multimodal User Interfaces. - : Springer. - 1783-7677 .- 1783-8738. ; 2, s. 133-144
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Tidskriftsartikel (refereegranskat)abstract
- In this paper we present the work that has been achieved in the context of the second version of the RAMCESS singing synthesis framework. The main improvement of this study is the integration of new algorithms for expressive voice analysis, especially the separation of the glottal source and the vocal tract. Realtime synthesis modules have also been refined. These elements have been integrated in an existing digital instrument: the HANDSKETCH 1.X, a bimanual controller. Moreover this digital instrument is compared to existing systems.
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| 17. |
- Demir, E. S., et al.
(författare)
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In vitro activity of ceragenins against Burkholderia cepacia complex
- 2022
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Ingår i: Journal of Antibiotics. - : Springer Nature. - 0021-8820 .- 1881-1469. ; 75:7, s. 403-409
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Tidskriftsartikel (refereegranskat)abstract
- Burkholderia cepacia complex (Bcc) species are aerobic, Gram-negative and non-fermantative bacilli. Bcc can cause clinical symptoms in patients with cystic fibrosis, ranging from asymptomatic carriage to fatal pneumonia. A pressing need exists for new antimicrobial agents that target Bcc. Ceragenins, CSA-13, CSA-131 and CSA-131 with 5% Pluronic® F127 (CSA-131P), were evaluated against Bcc clinical isolates (n = 42). MICs of ceragenins and conventional antibiotics were determined. Time-kill curve experiments were performed with 1x, 4x MICs of ceragenins and sulfamethoxazole-trimethoprim (SXT), levofloxacin. MIC50/ MIC90 results (mg l−1) of CSA-13, CSA-131 and CSA-131P were determined as 16/64, 16/128 and 16/128, respectively. CSA-13 and CSA-131 showed bactericidal activity. CSA-13 - levofloxacin combination displayed synergistic activity against Bcc. First-generation (CSA-13) and second-generation (CSA-131 and CSA-131P) ceragenins have significant antimicrobial effects on Bcc. The findings of this study demonstrate that combinations of ceragenins with currently marketed antibiotics could be synergistic in vitro against Bcc isolates. These results suggest that combination therapy with conventional antibiotics could be an alternative approach for treating Bcc infections in the future.
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| 18. |
- Haas, Brian J., et al.
(författare)
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Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans
- 2009
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 461:7262, s. 393-398
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Tidskriftsartikel (refereegranskat)abstract
- Phytophthora infestans is the most destructive pathogen of potato and a model organism for the oomycetes, a distinct lineage of fungus-like eukaryotes that are related to organisms such as brown algae and diatoms. As the agent of the Irish potato famine in the mid-nineteenth century, P. infestans has had a tremendous effect on human history, resulting in famine and population displacement(1). To this day, it affects world agriculture by causing the most destructive disease of potato, the fourth largest food crop and a critical alternative to the major cereal crops for feeding the world's population(1). Current annual worldwide potato crop losses due to late blight are conservatively estimated at $6.7 billion(2). Management of this devastating pathogen is challenged by its remarkable speed of adaptation to control strategies such as genetically resistant cultivars(3,4). Here we report the sequence of the P. infestans genome, which at similar to 240 megabases (Mb) is by far the largest and most complex genome sequenced so far in the chromalveolates. Its expansion results from a proliferation of repetitive DNA accounting for similar to 74% of the genome. Comparison with two other Phytophthora genomes showed rapid turnover and extensive expansion of specific families of secreted disease effector proteins, including many genes that are induced during infection or are predicted to have activities that alter host physiology. These fast-evolving effector genes are localized to highly dynamic and expanded regions of the P. infestans genome. This probably plays a crucial part in the rapid adaptability of the pathogen to host plants and underpins its evolutionary potential.
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| 21. |
- Kutkin, A. M., et al.
(författare)
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Apertif 1.4 GHz continuum observations of the Boötes field and their combined view with LOFAR
- 2023
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Ingår i: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 676
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Tidskriftsartikel (refereegranskat)abstract
- We present a new image of a 26.5 square degrees region in the Boötes constellation obtained at 1.4 GHz using the Aperture Tile in Focus (Apertif) system on the Westerbork Synthesis Radio Telescope. We use a newly developed processing pipeline that includes direction-dependent self-calibration, which provides a significant improvement in the quality of the images compared to those released as part of the Apertif first data release. For the Boötes region, we mosaicked 187 Apertif images and extracted a source catalog. The mosaic image has an angular resolution of 27 × 11.5″ and a median background noise of 40 μJy beam-1. The catalog has 8994 sources and is complete down to the 0.3 mJy level. We combined the Apertif image with LOFAR images of the Boötes field at 54 and 150 MHz to study the spectral properties of the sources. We find a spectral flattening toward sources with a low flux density. Using the spectral index limits from Apertif nondetections, we derive that up to 9% of the sources have ultrasteep spectra with a slope below -1.2. A steepening of the spectral index with increasing redshift is also seen in the data, which shows a different dependence for the low-and high-frequency spectral index. The explanation probably is that a population of sources has concave radio spectra with a turnover frequency of about the LOFAR band. Additionally, we discuss cases of individual extended sources with an interesting resolved spectral structure. With the improved pipeline, we aim to continue to process data from the Apertif wide-area surveys and release the improved 1.4-GHz images of several well-known fields.
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| 22. |
- Ovadia, C., et al.
(författare)
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Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses
- 2019
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Ingår i: The Lancet. - : Elsevier BV. - 0140-6736. ; 393:10174, s. 899-909
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Tidskriftsartikel (refereegranskat)abstract
- Background Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes, but the association with the concentration of specific biochemical markers is unclear. We aimed to quantify the adverse perinatal effects of intrahepatic cholestasis of pregnancy in women with increased serum bile acid concentrations and determine whether elevated bile acid concentrations were associated with the risk of stillbirth and preterm birth. Methods We did a systematic review by searching PubMed, Web of Science, and Embase databases for studies published from database inception to June 1, 2018, reporting perinatal outcomes for women with intrahepatic cholestasis of pregnancy when serum bile acid concentrations were available. Inclusion criteria were studies defining intrahepatic cholestasis of pregnancy based upon pruritus and elevated serum bile acid concentrations, with or without raised liver aminotransferase concentrations. Eligible studies were case-control, cohort, and population-based studies, and randomised controlled trials, with at least 30 participants, and that reported bile acid concentrations and perinatal outcomes. Studies at potential higher risk of reporter bias were excluded, including case reports, studies not comprising cohorts, or successive cases seen in a unit; we also excluded studies with high risk of bias from groups selected (eg, a subgroup of babies with poor outcomes were explicitly excluded), conference abstracts, and Letters to the Editor without clear peer review. We also included unpublished data from two UK hospitals. We did a random effects meta-analysis to determine risk of adverse perinatal outcomes. Aggregate data for maternal and perinatal outcomes were extracted from case-control studies, and individual patient data (IPD) were requested from study authors for all types of study (as no control group was required for the IPD analysis) to assess associations between biochemical markers and adverse outcomes using logistic and stepwise logistic regression. This study is registered with PROSPERO, number CRD42017069134. Findings We assessed 109 full-text articles, of which 23 studies were eligible for the aggregate data meta-analysis (5557 intrahepatic cholestasis of pregnancy cases and 165 136 controls), and 27 provided IPD (5269 intrahepatic cholestasis of pregnancy cases). Stillbirth occurred in 45 (0.83%) of 4936 intrahepatic cholestasis of pregnancy cases and 519 (0.32%) of 163 947 control pregnancies (odds ratio [OR] 1.46 [95% CI 0.73-2.89]; I-2 = 59.8%). In singleton pregnancies, stillbirth was associated with maximum total bile acid concentration (area under the receiver operating characteristic curve [ROC AUC]) 0.83 [95% CI 0.74-0.92]), but not alanine aminotransferase (ROC AUC 0.46 [0.35-0.57]). For singleton pregnancies, the prevalence of stillbirth was three (0.13%; 95% CI 0.02-0.38) of 2310 intrahepatic cholestasis of pregnancy cases in women with serum total bile acids of less than 40 mu mol/L versus four (0.28%; 0.08-0.72) of 1412 cases with total bile acids of 40-99 mu mol/L (hazard ratio [HR] 2.35 [95% CI 0.52-10.50]; p=0.26), and versus 18 (3.44%; 2.05-5.37) of 524 cases for bile acids of 100 mu mol/L or more (HR 30.50 [8.83-105.30]; p<0.0001). Interpretation The risk of stillbirth is increased in women with intrahepatic cholestasis of pregnancy and singleton pregnancies when serum bile acids concentrations are of 100 mu mol/L or more. Because most women with intrahepatic cholestasis of pregnancy have bile acids below this concentration, they can probably be reassured that the risk of stillbirth is similar to that of pregnant women in the general population, provided repeat bile acid testing is done until delivery. Funding Tommy's, ICP Support, UK National Institute of Health Research, Wellcome Trust, and Genesis Research Trust. Copyright (c) 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
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| 23. |
- Savarese, G, et al.
(författare)
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Correction
- 2023
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Ingår i: JACC. Heart failure. - 2213-1787. ; 11:12, s. 1773-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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