SwePub - sökning: WFRF:(Ehrenberg M)

Numrering	Referens	Omslagsbild	Hitta
1.	Walters, AS, et al. (författare) Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome 2003 Ingår i: Sleep medicine. - 1389-9457. ; 4:2, s. 121-132 Tidskriftsartikel (refereegranskat)
2.	Karlsson, M, et al. (författare) Initiation of Escherichia coli ribosomes on matrix coupled mRNAs studied by optical biosensor technique 1999 Ingår i: BIOCHIMIE. - : EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. - 0300-9084. ; 81:10, s. 995-1002 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract The optical biosensor technique, based on the surface plasmon resonance (SPR) phenomenon, has been used to study the initiation of protein synthesis by E. coli ribosomes on surface coupled mRNA. mRNA was first periodate oxidized and then hydrazide coupled
3.	Valle, M., Zavialov, A., Li, W., Stagg, S.M., Sengupta, J., Nielsen, R., Nissen, P., Harvey, S., Ehrenberg, M. and Frank, J. (författare) Incorporation of aminoacyl-tRNA in the ribosome as seen by cryo-EM. 2003 Ingår i: Nature Structural Biology. ; 10, s. 899-906 Tidskriftsartikel (refereegranskat)
4.	Ehrenberg, AJ, et al. (författare) Correction to: Relevance of biomarkers across different neurodegenerative diseases 2020 Ingår i: Alzheimer's research & therapy. - : Springer Science and Business Media LLC. - 1758-9193. ; 12:1, s. 71- Tidskriftsartikel (refereegranskat)abstract An amendment to this paper has been published and can be accessed via the original article.
5.	Freistroffer, DV, et al. (författare) The accuracy of codon recognition by polypeptide release factors 2000 Ingår i: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. - : NATL ACAD SCIENCES. - 0027-8424. ; 97:5, s. 2046-2051 Tidskriftsartikel (refereegranskat)abstract The precision with which individual termination codons in mRNA are recognized by protein release factors (RFs) has been measured and compared with the decoding of sense codons by tRNA, An Escherichia coil system for protein synthesis in vitro with purifie
6.	Göransson, K, et al. (författare) Thinking strategies used by registered nurses during emergency department triage 2008 Ingår i: Journal of Advanced Nursing. - 0309-2402 .- 1365-2648. ; 61:2, s. 163-172 Tidskriftsartikel (refereegranskat)
7.	Klaholz, B.P, Pape, T, Zavialov, A.V, Myasnikov, A.G., Orlova, E.V., Vestergaard, B, Ehrenberg, M and van Heel, M. (författare) Structure of the E.coli ribosomal termination complex with release factor 2 2003 Ingår i: journal. - : Nature. ; 421, s. 90-94 Tidskriftsartikel (refereegranskat)
8.	Klaholz, B.P., Pape, T.,. Zavialov, A.V., Myasnikov, A.G., Orlova, E.V., Vestergaard, B., Ehrenberg, M. and van Heel, M. (författare) . Structure of the E. coli ribosomal termination complex with release factor 2. 2003 Ingår i: Nature. ; 421, s. 90-94 Tidskriftsartikel (refereegranskat)
9.	Liang, ST, et al. (författare) Activities of constitutive promoters in Escherichia coli 1999 Ingår i: JOURNAL OF MOLECULAR BIOLOGY. - : ACADEMIC PRESS LTD. - 0022-2836. ; 292:1, s. 19-37 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract The in vivo activities of seven constitutive promoters in Escherichia coli have been determined as functions of growth rate in wild-type relA(+) spoT(+) strains with normal levels of guanosine tetraphosphate (ppGpp) and in ppGpp-deficient Delta relA Delta
10.	McDougall, J, Holst-Hansen, P, Mortensen, K.K, Freistroffer, D.V, Pavlov, M.Y., Ehrenberg, M, Buckingham, R.H. (författare) Purification of active Escherichia coli ribosome recycling factor, RRF, from an osmo-regulated expression system 1997 Ingår i: journal. - : Biochimie. ; 79, s. 243-246 Tidskriftsartikel (refereegranskat)
11.	McDougall, J, Holst-Hansen, P, Morstensen, K.K, Freistroffer, D.V., Pavlov, M.Y., Ehrenberg, M, Buckingham, R.H. (författare) Purification of active Escherichia coli ribosome recycling factor, RRF, from an osmo-regulated expression system. 1997 Ingår i: journal. - : Biochimie. ; 8, s. 243-246 Tidskriftsartikel (refereegranskat)
12.	Ortega, F, Ehrenberg, M, Acerenza, L, Westerhoff, H.V, and Cascante, M (författare) Sensitivity analysis of metabolic cascades catalyzed by bifunctional enzymes 2002 Ingår i: journal. - : Mol. Biol. Rep.. ; 29, s. 211-215 Tidskriftsartikel (refereegranskat)
13.	Pedersen, K., Zavialov, A., Pavlov, M., Elf, J., Gerdes, K. and Ehrenberg, M. (författare) The bacterial toxin RelE displays codon specific cleavage of mRNAs in the ribosomal A-site. 2003 Ingår i: Cell. ; 112, s. 131-140 Tidskriftsartikel (refereegranskat)
14.	Raine, A, et al. (författare) Targeting and insertion of heterologous membrane proteins in E. coli 2003 Ingår i: Biochimie. ; 85, s. 659-668 Tidskriftsartikel (refereegranskat)
15.	Refojo, Damian, et al. (författare) Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1 2011 Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 333:6051, s. 1903-1907 Tidskriftsartikel (refereegranskat)abstract The corticotropin-releasing hormone receptor 1 (CRHR1) critically controls behavioral adaptation to stress and is causally linked to emotional disorders. Using neurochemical and genetic tools, we determined that CRHR1 is expressed in forebrain glutamatergic and gamma-aminobutyric acid-containing (GABAergic) neurons as well as in midbrain dopaminergic neurons. Via specific CRHR1 deletions in glutamatergic, GABAergic, dopaminergic, and serotonergic cells, we found that the lack of CRHR1 in forebrain glutamatergic circuits reduces anxiety and impairs neurotransmission in the amygdala and hippocampus. Selective deletion of CRHR1 in midbrain dopaminergic neurons increases anxiety-like behavior and reduces dopamine release in the prefrontal cortex. These results define a bidirectional model for the role of CRHR1 in anxiety and suggest that an imbalance between CRHR1-controlled anxiogenic glutamatergic and anxiolytic dopaminergic systems might lead to emotional disorders.
16.	Tenson, T., Lovmar, M. and Ehrenberg, M. (författare) The mechanism of action of MLS antibiotics reveals the nascent peptide exit path in the ribosome. 2003 Ingår i: J. Mol. Biol.. ; 330, s. 1005-1014 Tidskriftsartikel (refereegranskat)
17.	Valle, M., Zavialov, A., Sengupta, J., Rawat, U., Ehrenberg, M. and Frank, J. (författare) Locking and unlocking of ribosomal motions. 2003 Ingår i: Cell. ; 114, s. 123-134 Tidskriftsartikel (refereegranskat)
18.	Westerholm, R, et al. (författare) Comparison of exhaust emissions from Swedish environmental classified diesel fuel (MK1) and European Program on Emissions, Fuels and Engine Technologies (EPEFE) reference fuel: a chemical and biological characterization, with viewpoints on cancer risk 2001 Ingår i: Environmental science & technology. - : American Chemical Society (ACS). - 0013-936X .- 1520-5851. ; 35:9, s. 1748-1754 Tidskriftsartikel (refereegranskat)
19.	Zohari, Siamak, et al. (författare) Phylogenetic analysis of the non-structural (NS) gene of influenza A viruses isolated from mallards in Northern Europe in 2005 2008 Ingår i: Virology Journal. - 1743-422X. ; 5:Article ID: 147 Tidskriftsartikel (refereegranskat)abstract Background: Although the important role of the non-structural 1 (NS) gene of influenza A in virulence of the virus is well established, our knowledge about the extent of variation in the NS gene pool of influenza A viruses in their natural reservoirs in Europe is incomplete. In this study we determined the subtypes and prevalence of influenza A viruses present in mallards in Northern Europe and further analysed the NS gene of these isolates in order to obtain a more detailed knowledge about the genetic variation of NS gene of influenza A virus in their natural hosts. Results: A total number of 45 influenza A viruses of different subtypes were studied. Eleven haemagglutinin-and nine neuraminidase subtypes in twelve combinations were found among the isolated viruses. Each NS gene reported here consisted of 890 nucleotides; there were no deletions or insertions. Phylogenetic analysis clearly shows that two distinct gene pools, corresponding to both NS allele A and B, were present at the same time in the same geographic location in the mallard populations in Northern Europe. A comparison of nucleotide sequences of isolated viruses revealed a substantial number of silent mutations, which results in high degree of homology in amino acid sequences. The degree of variation within the alleles is very low. In our study allele A viruses displays a maximum of 5% amino acid divergence while allele B viruses display only 2% amino acid divergence. All the viruses isolated from mallards in Northern Europe possessed the typical avian ESEV amino acid sequence at the C-terminal end of the NSI protein. Conclusion: Our finding indicates the existence of a large reservoir of different influenza A viruses in mallards population in Northern Europe. Although our phylogenetic analysis clearly shows that two distinct gene pools, corresponding to both NS allele A and B, were present in the mallards populations in Northern Europe, allele B viruses appear to be less common in natural host species than allele A, comprising only about 13% of the isolates sequenced in this study.
20.	Arkov, AL, et al. (författare) Mutations in conserved regions of ribosomal RNAs decrease the productive association of peptide-chain release factors with the ribosome during translation termination 2000 Ingår i: BIOCHIMIE. - : EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. - 0300-9084. ; 82:8, s. 671-682 Tidskriftsartikel (refereegranskat)abstract Early studies provided evidence that peptide-chain release factors (RFs) bind to both ribosomal subunits and trigger translation termination. Although many ribosomal proteins have been implicated in termination, very few data present direct biochemical ev
21.	Arkov, AL, et al. (författare) Mutations in RNAs of both ribosomal subunits cause defects in translation termination 1998 Ingår i: EMBO JOURNAL. - : OXFORD UNIV PRESS. - 0261-4189. ; 17:5, s. 1507-1514 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract Mutations in RNAs of both subunits of the Escherichia coil ribosome caused defects in catalysis of peptidyl-tRNA hydrolysis in a realistic in vitro termination system. Assaying the two codon-dependent cytoplasmic proteins that drive termination, RF1 and R
22.	Asplund, K, et al. (författare) [SBU about "lean": Process-oriented work in emergency departments yields shorter through-put] 2010 Ingår i: Lakartidningen. - 0023-7205. ; 107:17, s. 1164- Tidskriftsartikel (refereegranskat)
23.	Berg, Lena M, et al. (författare) An observational study of activities and multitasking performed by clinicians in two Swedish emergency departments 2012 Ingår i: European journal of emergency medicine. - London : Chapman & Hall. - 0969-9546 .- 1473-5695. ; 19:4, s. 246-251 Tidskriftsartikel (refereegranskat)abstract Objectives: To explore the type and frequency of activities and multitasking performed by emergency department clinicians.Methods: Eighteen clinicians (licensed practical nurses, registered nurses and medical doctors), six from each occupational group, at two Swedish emergency departments were followed in their clinical work for 2 h each to observe all their activities and multitasking practices. Data were analysed using qualitative and quantitative content analysis.Results: Fifteen categories of activities could be identified based on 1882 observed activities during the 36 h of observation. The most common activity was information exchange, which was most often performed face-to-face. This activity represented 42.1% of the total number of observed activities. Information exchange was also the most common activity to be multitasked. Registered nurses performed most activities and their activities were multitasked more than the other clinicians. The nurses’ and doctors’ offices were the most common locations for multitasking in the emergency department.Conclusion: This study provides new knowledge regarding the activities conducted by clinicians in the emergency department. The most frequent activity was information exchange, which was the activity most often performed by the clinicians when multitasking occurred. Differences between clinicians were found for activities performed and multitasked, with registered nurses showing the highest frequencies for both.
24.	Berg, Lena M, et al. (författare) Associations between crowding and ten-day mortality among patients allocated lower triage acuity levels without need of acute hospital care on departure from the emergency department 2019 Ingår i: Annals of Emergency Medicine. - : Elsevier BV. - 0196-0644 .- 1097-6760. ; 74:3, s. 345-356 Tidskriftsartikel (refereegranskat)abstract STUDY OBJECTIVE: We describe the association between emergency department (ED) crowding and 10-day mortality for patients triaged to lower acuity levels at ED arrival and without need of acute hospital care on ED departure.METHODS: This was a registry study based on ED visits with all patients aged 18 years or older, with triage acuity levels 3 to 5, and without need of acute hospital care on ED departure during 2009 to 2016 (n=705,699). The sample was divided into patients surviving (n=705,076) or dying (n=623) within 10 days. Variables concerning patient characteristics and measures of ED crowding (mean length of stay and ED occupancy ratio) were extracted from the hospital's electronic health records. ED length of stay per ED visit was estimated by the average length of stay for all patients who presented to the ED during the same day and shift and with the same acuity level. The 10-day mortality after ED discharge was used as the outcome measure. Multivariable logistic regression analyses were conducted.RESULTS: The 10-day mortality rate was 0.09% (n=623). The event group had larger proportions of patients aged 80 years or older (51.4% versus 7.7%) and triaged with acuity level 3 (63.3% versus 35.6%), and greater comorbidity (age-combined Charlson comorbidity index median interquartile range 6 versus 0). We observed an increased 10-day mortality for patients with a mean ED length of stay greater than or equal to 8 hours versus less than 2 hours (adjusted odds ratio 5.86; 95% confidence interval [CI] 2.15 to 15.94) and for elevated ED occupancy ratio. Adjusted odds ratios for ED occupancy ratio quartiles 2, 3, and 4 versus quartile 1 were 1.48 (95% CI 1.14 to 1.92), 1.63 (95% CI 1.24 to 2.14), and 1.53 (95% CI 1.15 to 2.03), respectively.CONCLUSION: Patients assigned to lower triage acuity levels when arriving to the ED and without need of acute hospital care on departure from the ED had higher 10-day mortality when the mean ED length of stay exceeded 8 hours and when ED occupancy ratio increased.
25.	Berg, Lena M, et al. (författare) Factors influencing clinicians' perceptions of interruptions as disturbing or non-disturbing : a qualitative study 2016 Ingår i: International Emergency Nursing. - : Elsevier. - 1755-599X .- 1878-013X. ; 27, s. 11-16 Tidskriftsartikel (refereegranskat)abstract OBJECTIVE: Emergency departments consist of multiple systems requiring interaction with one another while still being able to operate independently, creating frequent interruptions in the clinical workflow. Most research on interruptions in health care settings has focused on the relationship between interruptions and negative outcomes. However, there are indications that not all interruptions are negatively perceived by those being interrupted. Therefore, this study aimed to explore factors that influence when a clinician perceives interruptions as non-disturbing or disturbing in an emergency department context.METHOD: Explorative design based on interviews with 10 physicians and 10 registered nurses at two Swedish emergency departments. Data were analyzed using qualitative content analysis.RESULT: Factors influencing whether emergency department clinicians perceived interruptions as non-disturbing or disturbing were identified: clinician's constitution, external factors of influence and the nature of the interrupted task. The clinicians' perceptions were related to a complex of attributes inherent in these three factors at the time of the interruption. Thus, the same type of interruption could be perceived as either non-disturbing or disturbing contingent on the surrounding circumstances in which the event occurred.CONCLUSION: Emergency department clinicians' perceptions of interruptions as non-disturbing or disturbing were related to the character of identified influencing factors.

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