| 1. |
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| 2. |
- Outola, I., et al.
(författare)
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Characterization of the NIST Seaweed Standard Reference Material
- 2006
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Ingår i: Applied Radiation and Isotopes. - : Elsevier BV. - 0969-8043. ; 64:10-11, s. 1242-1247
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Tidskriftsartikel (refereegranskat)abstract
- The National Institute of Standards and Technology (NIST) Standard Reference Material (SRM) for seaweed was developed through an interlaboratory comparison with 24 participants from 16 countries. After evaluating different techniques to calculate certified values for the radionuclides, the median method was found to be the most representative technique. The certified values were provided for 13 radionuclides and information values were given for 15 more radionuclides. Results for the natural decay series showed disequilibrium in both the uranium and thorium series. (c) 2006 Elsevier Ltd. All rights reserved.
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| 3. |
- Regev, A, et al.
(författare)
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The Human Cell Atlas
- 2017
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Ingår i: eLife. - : ELIFE SCIENCES PUBLICATIONS LTD. - 2050-084X. ; 6
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Tidskriftsartikel (refereegranskat)
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| 4. |
- Caton, Summer A., et al.
(författare)
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Evolution of the sources of TTG and associated rocks during the Archean from in-situ 87Sr/86Sr isotope analysis of apatite by LA-MC-ICPMS
- 2022
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Ingår i: Lithos. - : Elsevier BV. - 0024-4937 .- 1872-6143. ; 428-429
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Tidskriftsartikel (refereegranskat)abstract
- Radiogenic isotopes provide an important means towards elucidating Archean crustal evolution. The global Hf and Nd isotope record of Archean crustal fragments has been instrumental to unveiling the history of ancient crustal growth and differentiation. The Rb-Sr system could provide valuable complementary constraints in this regard, as this system is particularly sensitive to magmatic fractionation processes, and the chemical and isotopic evolution of magma sources. Application of this system has so far been complicated, however, by its susceptibility to isotope re-equilibration or alteration of the Rb/Sr parent-daughter ratio. In-situ Sr isotope analysis of primary igneous minerals with very low Rb/Sr, such as apatite, provides a new means to determine the initial 87Sr/86Sr (87Sr/86Sri) values for igneous rocks directly. In this study, we apply in-situ Sr isotope analysis of apatite by LA-MC-ICPMS to tonalite-trondhjemite-granodiorite (TTG) rocks and end-member sanukitoids from Archean cratons worldwide. The 87Sr/86Sri values of sanukitoids are relatively radiogenic, supporting the model in which such rocks are formed by flux melting of a mantle strongly enriched by metasomatism, possibly by slab-derived fluids. The 87Sr/86Sri values for TTGs formed between 3.72 and 3.45 Ga are generally radiogenic, indicating aged amphibolite sources. The 87Sr/86Sri values of younger TTGs are systematically lower and were derived from mafic sources that had an average age of ≤0.2 Gyr. This evolution matches with observations from Hf isotopes for TTGs of similar age and indicates a systematic change in the nature or efficiency of TTG crust formation during the Paleoarchean. In-situ Sr isotope analysis of apatite provides a useful method to uncover the Sr record of the early continental crust, and enables constraints on local source evolution and the general two-step evolutionary process of Archean crust formation.
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| 5. |
- Pham, M. K., et al.
(författare)
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A new Certified Reference Material for radionuclides in Irish sea sediment (IAEA-385)
- 2008
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Ingår i: APPLIED RADIATION AND ISOTOPES. - : Elsevier BV. - 1872-9800 .- 0969-8043. ; 66:11, s. 1711-1717
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Konferensbidrag (refereegranskat)abstract
- A new Certified Reference Material (CRM) for radionuclides in sediment (IAEA-385) is described and the results of the certification process are presented. Eleven radionuclides (K-40, Cs-137, Ra-226, Ra-228, Th-230, Th-232, U-234, U-238, Pu-238, Pu239+240 and Am-241) have been certified and information mass activities with 95% confidence intervals are given for seven other radionuclides (Sr-90, Pb-210(Po-210), U-235, Pu-239, Pu-240 and Pu-241). Results for less frequently reported radionuclides (Co-60, Tc-99, Cs-134, Eu-155, Ra-224 and Np-239) and information on some activity and mass ratios are also reported. The CRM can be used for quality assurance/quality control of the analysis of radionuclides in sediment samples, for the development and validation of analytical methods and for training purposes. (C) 2008 IAEA. Published by Elsevier Ltd. All rights reserved.
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| 6. |
- Pham, M. K., et al.
(författare)
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A new reference material for radionuclides in the mussel sample from the Mediterranean Sea (IAEA-437)
- 2010
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Ingår i: Journal of Radioanalytical and Nuclear Chemistry. - : Springer Science and Business Media LLC. - 0236-5731 .- 1588-2780. ; 283:3, s. 851-859
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Tidskriftsartikel (refereegranskat)abstract
- A new Reference Material (RM) for radionuclides in mussel (Mytilus galloprovincialis) from the Mediterranean Sea (IAEA-437) is described and the results of the certification process are presented. Four radionuclides (K-40, U-234, U-238, and Pu239+240) have been certified, and information values on massic activities with 95% confidence intervals are given for nine radionuclides (Cs-137, Pb-210(Po-210), Ra-226, Ra-228, Th-228, Th-230, Th-232, U-235, and Am-241). Results for less frequently reported radionuclides (Sr-90, I-129, Pu-238, Pu-239, and Pu-240) are also reported. The RM can be used for quality assurance/quality control of the analysis of radionuclides in mussel samples, for the development and validation of analytical methods and for training purposes. The material is available in 200 g units.
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| 7. |
- Pham, M. K., et al.
(författare)
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Certified reference material for radionuclides in fish flesh sample IAEA-414 (mixed fish from the Irish Sea and North Sea)
- 2006
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Ingår i: Proceedings of the 15th International Conference on Radionuclide Metrology and its Applications (Applied Radiation and Isotopes). - Amsterdam : Elsevier BV. - 1872-9800 .- 0969-8043. ; 64:10-11, s. 1253-1259
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Konferensbidrag (refereegranskat)abstract
- A certified reference material (CRM) for radionuclides in fish sample IAEA-414 (mixed fish from the Irish Sea and North Seas) is described and the results of the certification process are presented. Nine radionuclides (K-40, Cs-137, Th-232, U-234, U-235, U-238, Pu-238, Pu239+240 and Am-241) were certified for this material. Information on massic activities with 95% confidence intervals is given for six other radionuclides (Sr-90, Pb-210(Po-210), Ra-226, Pu-239, Pu-240 Pu-241). Less frequently reported radionuclides (Tc-99, I-129, Th-228, Th-230 and Np-217) and information on some activity and mass ratios are also included. The CRM can be used for quality assurance/quality control of the analysis of radionuclides in fish sample, for the development and validation of analytical methods and for training purposes. The material is available from IAEA, Vienna, in 100 g units.
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| 8. |
- Maccubbin, D., et al.
(författare)
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Lipid-modifying efficacy and tolerability of extended-release niacin/laropiprant in patients with primary hypercholesterolaemia or mixed dyslipidaemia
- 2008
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Ingår i: International journal of clinical practice (Esher). - : Hindawi Limited. - 1368-5031 .- 1742-1241. ; 62:12, s. 1959-1970
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Tidskriftsartikel (refereegranskat)abstract
- Background: Improving lipids beyond low-density lipoprotein cholesterol (LDL-C) lowering with statin monotherapy may further reduce cardiovascular risk. Niacin has complementary lipid-modifying efficacy to statins and cardiovascular benefit, but is underutilised because of flushing, mediated primarily by prostaglandin D2 (PGD2). Laropiprant (LRPT), a PGD 2 receptor (DP1) antagonist that reduces niacin-induced flushing has been combined with extended-release niacin (ERN) into a fixed-dose tablet. Methods and results: Dyslipidaemic patients were randomised to ERN/LRPT 1 g (n = 800), ERN 1 g (n = 543) or placebo (n = 270) for 4 weeks. Doses were doubled (2 tablets/day, i.e. 2 g for active treatments) for 20 weeks. ERN/LRPT 2 g produced significant changes vs. placebo in LDL-C (-18.4%), high-density lipoprotein cholesterol (HDL-C, 20.0%), LDL-C:HDL-C (-31.2%), non-HDL-C (-19.8%), triglycerides (TG, -25.8%), apolipoprotein (Apo) B (-18.8%), Apo A-I (6.9%), total cholesterol (TC, -8.5%), TC:HDL-C (-23.1%) and lipoprotein(a) (-20.8%) across weeks 12-24. ERN/LRPT produced significantly less flushing than ERN during initiation (week 1) and maintenance (weeks 2-24) for all prespecified flushing end-points (incidence, intensity and discontinuation because of flushing). Except for flushing, ERN/LRPT had a safety/tolerability profile comparable with ERN. Conclusion: Extended-release niacin/LRPT 2 g produced significant, durable improvements in multiple lipid/lipoprotein parameters. The improved tolerability of ERN/LRPT supports a simplified 1 g?2 g dosing regimen of niacin, a therapy proven to reduce cardiovascular risk. © 2008 Merck & Co.
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| 9. |
- Vandenhove, H., et al.
(författare)
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Short rotation coppice for revaluation of contaminated land
- 2001
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Ingår i: Journal of Environmental Radioactivity. - 1879-1700. ; 56:1-2, s. 157-184
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Tidskriftsartikel (refereegranskat)abstract
- When dealing with large-scale environmental contamination, as following the Chernobyl accident, changed land use such that the products of the land are radiologically acceptable and sustain an economic return from the land is a potentially sustainable remediation option. In this paper, willow short rotation coppice (SRC) is evaluated on radiological, technical and economic grounds for W. European and Belarus site conditions. Radiocaesium uptake was studied in a newly established and existing SRC. Only for light-texture soils with low soil potassium should cultivation be restricted to soils with contamination levels below 100 370 kBq m(-2) given the TFs on these soils (5 x 10(-4) and 2 x 10(-3) m(2) kg(-1)) and considering the Belarus exemption limit for firewood (740 Bq kg(-1)). In the case of high wood contamination levels ( > 1000 Bq kg(-1)). power plant personnel working in the vicinity of ash conveyers should be subjected to radiation protection measures. For appropriate soil conditions, potential SRC yields are high. In Belarus, most soils are sandy with a low water retention, for which yield estimates are too low to make production profitable without irrigation. The economic viability should be thoroughly calculated for the prevailing conditions. In W. Europe, SRC production or conversion is not profitable without price incentives. For Belarus, the profitability of SRC on the production side largely depends on crop yield and price of the delivered bio-fuel. Large-scale heat conversion systems seem the most profitable and revenue may be considerable. Electricity routes are usually unprofitable. It could be concluded that energy production from SRC is potentially a radiologically and economically sustainable land use option for contaminated agricultural land.
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| 10. |
- Envall, Elis, et al.
(författare)
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Papperslösa
- 2010
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Ingår i: Social Rapport 2010. - Stockholm : Socialstyrelsen. - 9789186585006
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Sammanfattning • Det finns ingen tillförlitlig statistik över antalet papperslösa personer i Sverige, men viss forsk- ning och mindre undersökningar har uppskatt- ningar som talar om mellan 10 000 och 50 000 personer. I gruppen ingår enligt osäkra skatt- ningar cirka 2 000–3 000 barn. Totalt inom EU uppskattas antalet papperslösa till mellan knappt tre och åtta miljoner. •Papperslösa är hänvisade till den informella ar- betsmarknaden för sin försörjning. Många sak- nar arbete eller har endast sporadiskt arbete. Papperslösa bor ofta trångt och under osäkra förhållanden. • Papperslösa har begränsade möjligheter till vård och hälsotillståndet bland många av dem är dåligt eller mycket dåligt enligt flera studier. Socialtjänstens kontakter med den här gruppen är begränsade. •Det finns tecken på att många av de papperslö- sa barn som lever gömda har psykiska problem. •Ett ökande antal barn och unga utan vårdnads- havare söker asyl, och en betydande del av dessa avviker från sitt boende. •Barn till papperslösa föräldrar folkbokförs inte och identifieras inte genom person- eller sam- ordningsnummer, vilket bland annat påverkar möjligheterna till medicinsk uppföljning. • Olika politikerområden har olika mål. Dessa är inte alltid förenliga med de papperslösas si- tuation. Detta kan leda till svåra dilemman för personal som ska tillämpa lagstiftning inom socialtjänsten, hälso- och sjukvården, skolan och Migrationsverket.
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| 11. |
- Gomez-Guzman, J. M., et al.
(författare)
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Analysis of I-129 in lichens by accelerator mass spectrometry through a microwave-based sample preparation method
- 2010
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Ingår i: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. - : Elsevier BV. - 0168-583X. ; 268:7-8, s. 1171-1174
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Konferensbidrag (refereegranskat)abstract
- The presence of I-129 in the environment has been strongly influenced by the artificial nuclear emissions since the beginning of the nuclear era in the mid 20th century. In order to know more about the different sources and their relative impact in different zones, it is necessary to complete the amount of measurements of this radionuclide in environmental samples. In this work, I-129 has been determined in lichen samples (Cladonia alpestris) from Rogen Lake in Central Sweden. A method based on microwave digestion was developed for these measurements in order to improve speed and reduce contamination. Based on this method, I-129 concentrations in some lichen samples from Lake Rogen (Sweden) have been measured, showing the impact of the Chernobyl accident and nuclear fuel reprocessing plants. (C) 2009 Elsevier B.V. All rights reserved.
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| 12. |
- Holm, Elis, et al.
(författare)
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Curium isotopes in Chernobyl fallout
- 2002
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Ingår i: Journal of Radioanalytical and Nuclear Chemistry. - 0236-5731. ; 252:2, s. 211-214
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Tidskriftsartikel (refereegranskat)abstract
- In nuclear reactors plutonium and transplutonium isotopes are produced by multiple neutron capture of uranium and plutonium and are important for the energy production and their composition reflects the core burnout. Under normal operation these elements are not released to the environment in significant amounts. There are accordingly very few areas or source terms where exotic transplutonium elements, such as curium isotopes, can be studied in the environment. The Chernobyl accident provided a complex spectrum of fission and activation products in fallout while the relative amounts, compared to the core inventory, of refractory elements such as transuranium and transplutonium elements were small. The major alpha-activity consisted of Cm-242 (T-1/2=163 d) that would have decayed after a few years. In this study we have demonstrated the presence of so called "supported Cm-242" from the long-lived Am-242(m) (T-1/2=141 a) in environmental samples, following fallout from the Chernobyl accident. It has also been possible to assess the core bum up by using the data obtained for the Cm isotopes. The curium isotopes Cm-243 (T-1/2=29.1 a) and Cm-244 (T-1/2=18.1 a) cannot be resolved by conventional alpha-spectrometry. The assessment of these isotopes in environmental samples contaminated from the Chernobyl accident has been made by studying the effective half-life of the mixture of the isotopes. The data are compared with those previously obtained by high-resolution alpha-spectrometry and spectral deconvolution.
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| 13. |
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| 14. |
- Yilmaz-Elis, A Seda, et al.
(författare)
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FcγRIIb on myeloid cells rather than on B cells protects from collagen-induced arthritis
- 2014
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Ingår i: Journal of Immunology. - : The American Association of Immunologists. - 0022-1767 .- 1550-6606. ; 192:12, s. 5540-5547
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Tidskriftsartikel (refereegranskat)abstract
- Extensive analysis of a variety of arthritis models in germline KO mice has revealed that all four receptors for the Fc part of IgG (FcγR) play a role in the disease process. However, their precise cell type-specific contribution is still unclear. In this study, we analyzed the specific role of the inhibiting FcγRIIb on B lymphocytes (using CD19Cre mice) and in the myeloid cell compartment (using C/EBPαCre mice) in the development of arthritis induced by immunization with either bovine or chicken collagen type II. Despite their comparable anti-mouse collagen autoantibody titers, full FcγRIIb knockout (KO), but not B cell-specific FcγRIIb KO, mice showed a significantly increased incidence and severity of disease compared with wild-type control mice when immunized with bovine collagen. When immunized with chicken collagen, disease incidence was significantly increased in pan-myeloid and full FcγRIIb KO mice, but not in B cell-specific KO mice, whereas disease severity was only significantly increased in full FcγRIIb KO mice compared with incidence and severity in wild-type control mice. We conclude that, although anti-mouse collagen autoantibodies are a prerequisite for the development of collagen-induced arthritis, their presence is insufficient for disease development. FcγRIIb on myeloid effector cells, as a modulator of the threshold for downstream Ab effector pathways, plays a dominant role in the susceptibility to collagen-induced arthritis, whereas FcγRIIb on B cells, as a regulator of Ab production, has a minor effect on disease susceptibility.
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