| 1. |
- Latini, Francesco, 1982-, et al.
(författare)
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Segmentation of the inferior longitudinal fasciculus in the human brain : A white matter dissection and diffusion tensor tractography study
- 2017
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Ingår i: Brain Research. - : Elsevier. - 0006-8993 .- 1872-6240. ; 1675, s. 102-115
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Tidskriftsartikel (refereegranskat)abstract
- The inferior longitudinal fascicle (ILF) is one of the major occipital-temporal association pathways. Several studies have mapped its hierarchical segmentation to specific functions. There is, however, no consensus regarding a detailed description of ILF fibre organisation. The aim of this study was to establish whether the ILF has a constant number of subcomponents. A secondary aim was to determine the quantitative diffusion proprieties of each subcomponent and assess their anatomical trajectories and connectivity patterns. A white matter dissection of 14 post-mortem normal human hemispheres was conducted to define the course of the ILF and its subcomponents. These anatomical results were then investigated in 24 right-handed, healthy volunteers using in vivo diffusion tensor imaging (DTI) and streamline tractography. Fractional anisotropy (FA), volume, fibre length and the symmetry coefficient of each fibre group were analysed. In order to show the connectivity pattern of the ILF, we also conducted an analysis of the cortical terminations of each segment. We confirmed that the main structure of the ILF is composed of three constant components reflecting the occipital terminations: the fusiform, the lingual and the dorsolateral-occipital. ILF volume was significantly lateralised to the right. The examined indices of ILF subcomponents did not show any significant difference in lateralisation. The connectivity pattern and the quantitative distribution of ILF subcomponents suggest a pivotal role for this bundle in integrating information from highly specialised modular visual areas with activity in anterior temporal territory, which has been previously shown to be important for memory and emotions.
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| 2. |
- Anna, Malm, 1978, et al.
(författare)
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Production start-up phase - A comparison between New Product Development and Production Relocation
- 2012
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Ingår i: Proceedings of the 5th International Swedish Production Symposium. - 9789175197524 ; , s. 593-598
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Konferensbidrag (refereegranskat)abstract
- New product development in a globalized industrial environment with a constant increasing competition, challenges the ways to perform production start-up and production relocation. A product development process focuses in general on product function and to avoid product quality problems. A production relocation focus also on avoiding product quality problems, but relocation is mostly related to forgotten or misunderstood information. The challenging situation due to a more global market is the increasing need for production relocation. In this paper, a literature review is performed investigating these three areas and relate them with industrial experience from production relocations. To summaries, the existing processes in industry today seem to be based on processes for product development. The results view that effectiveness in production relocation are dependent on technology and knowledge transfer and the production start-up process.
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| 3. |
- Bertilsson, Johan, et al.
(författare)
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Stress Levels Escalate When Repeatedly Performing Tasks Involving Threats
- 2019
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Ingår i: Frontiers in Psychology. - : Frontiers Media SA. - 1664-1078. ; 10, s. 1562-1562
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Tidskriftsartikel (refereegranskat)abstract
- Police work may include performing repeated tasks under the influence of psychological stress, which can affect perceptual, cognitive and motor performance. However, it is largely unknown how repeatedly performing stressful tasks physically affect police officers in terms of heart rate and pupil diameter properties. Psychological stress is commonly assessed by monitoring the changes in these biomarkers. Heart rate and pupil diameter was measured in 12 male police officers when performing a sequence of four stressful tasks, each lasting between 20 and 130 s. The participants were first placed in a dimly illuminated anteroom before allowed to enter a brightly lit room where a scenario was played out. After each task was performed, the participants returned to the anteroom for about 30 s before performing the next sequential task. Performing a repeated sequence of stressful tasks caused a significant increase in heart rate (p = 0.005). The heart rate started to increase already before entering the scenario room and was significantly larger just after starting the task than just before starting the task (p < 0.001). This pattern was more marked during the first tasks (p < 0.001). Issuance of a verbal "abort" command which terminated the tasks led to a significant increase of heart rate (p = 0.002), especially when performing the first tasks (p = 0.002). The pupil diameter changed significantly during the repeated tasks during all phases but in a complex pattern where the pupil diameter reached a minimum during task 2 followed by an increase during tasks 3 and 4 (p ≤ 0.020). During the initial tasks, the pupil size (p = 0.014) increased significantly. The results suggest that being repeatedly exposed to stressful tasks can produce in itself an escalation of psychological stress, this even prior to being exposed to the task. However, the characteristics of both the heart rate and pupil diameter were complex, thus, the findings highlight the importance of studying the effects and dynamics of different stress-generating factors. Monitoring heart rate was found useful to screen for stress responses, and thus, to be a vehicle for indication if and when rotation of deployed personnel is necessary to avoid sustained high stress exposures.
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| 4. |
- Bertilsson, Johan, et al.
(författare)
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Towards systematic and objective evaluation of police officer performance in stressful situations
- 2020
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Ingår i: Police Practice and Research. - : Informa UK Limited. - 1561-4263 .- 1477-271X. ; 21:6, s. 655-669
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Tidskriftsartikel (refereegranskat)abstract
- To ensure a continuous high standard of police units, it is critical to recruit people who perform well in stressful situations. Today, this selection process includes performing a large series of tests, which still may not objectively reveal a person’s capacity to handle a life-threatening situation when subjected to high levels of stress. To obtain more systematic and objective data, 12 police officers were exposed to six scenarios with varying levels of threat while their heart rate and pupil size were monitored. The scenarios were filmed and six expert evaluators assessed the performance of the police officers according to seven predefined criteria. Four of the scenarios included addressing a moderate threat level task and the scenarios were executed in a rapid sequence. Two further scenarios included a familiar firearm drill performed during high and low threat situations. The results showed that there was a large agreement between the experts in how they judged the performance of the police officers (p < 0.001). Performance increased significantly over tasks in four of the seven evaluation criteria (p ≤ 0.037). There was also a significant effect of pupil size (p = 0.004), but not heart rate, when comparing the different sequential scenarios. Moreover, a high level of threat considerably impaired the motor performance of the police officers during the firearms drill (p = 0.002). Finally, the pupil seemed to systematically dilate more when a threat appeared immediately than with a delay in the scenarios (p = 0.007). We conclude that systematic and quantitative judgments from experts provide valuable and reliable information about the performance of participants in realistic and stressful policing scenarios. Furthermore, objective physiological measures of heart rate and pupil size may help to explain and understand why performance sometimes deteriorates.
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| 5. |
- Boström, A., et al.
(författare)
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Risk factors for acute and overuse sport injuries in Swedish children 11 to 15 years old : What about resistance training with weights?
- 2016
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Ingår i: Scandinavian Journal of Medicine and Science in Sports. - : John Wiley & Sons. - 0905-7188 .- 1600-0838. ; 26:3, s. 317-323
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Tidskriftsartikel (refereegranskat)abstract
- To determine the 1-year self-reported incidence of overuse and traumatic sport injuries and risk factors for injuries in children participating in a summer sports camp representing seven different sports. 4363 children, 11 to 15 years old participating in a summer camp in seven different sports answered a questionnaire. Injury in this cross-sectional study was defined as a sport-related trauma or overload leading to pain and dysfunction preventing the person from participation in training or competition for at least 1 week. A number of risk factors for injury were investigated such as sex, age, number of hours spent on training in general, and on resistance training with weights. Nearly half [49%, 95% confidence interval (CI) 48–51%] of the participants had been injured as a result of participation in a sport during the preceding year, significantly more boys than girls (53%, 95% CI 50–55% vs 46%, 95% CI 43–48%; P < 0.001). Three factors contributed to increased incidence of sport injuries: age, sex, and resistance training with weights. Time spent on resistance training with weights was significantly associated with sport injuries in a logistic regression analysis. In children age 11 to 15 years, the risk of having a sport-related injury increased with age and occurred more often in boys than in girls. Weight training was the only modifiable risk factor that contributed to a significant increase in the incidence of sport injuries.
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| 6. |
- Hudson, Lawrence N, et al.
(författare)
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The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
- 2017
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Ingår i: Ecology and Evolution. - : John Wiley & Sons. - 2045-7758. ; 7:1, s. 145-188
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Tidskriftsartikel (refereegranskat)abstract
- The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity.
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| 7. |
- Landegren, Ulf, et al.
(författare)
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Molecular tools for a molecular medicine : analyzing genes, transcripts and proteins using padlock and proximity probes
- 2004
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Ingår i: Journal of Molecular Recognition. - : Wiley. - 0952-3499 .- 1099-1352. ; 17:3, s. 194-7
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Tidskriftsartikel (refereegranskat)abstract
- Procedures and reagents are needed to specifically detect all the macromolecules that are being identified in the course of genome projects. We discuss how this challenge may be met using a set of ligation-based reagents termed padlock probes and proximity ligation probes. These probes include elements with affinity for specific nucleic acid and protein molecules, respectively, along with unique identifier DNA sequence elements that encode the identity of the recognized target molecules. The information content of DNA strands that form in the detection reactions are recorded after amplification, allowing the recognized target molecules to be identified. The procedures permit highly specific solution-phase or localized analyses of large sets of target molecules as required in future molecular analyses.
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| 8. |
- Landegren, Ulf, et al.
(författare)
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Padlock and proximity probes for in situ and array-based analyses : tools for the post genomic era
- 2003
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Ingår i: Comparative and functional genomics. - : Hindawi Limited. - 1531-6912 .- 1532-6268. ; 4:5, s. 525-30
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Tidskriftsartikel (refereegranskat)abstract
- Highly specific high-throughput assays will be required to take full advantage of the accumulating information about the macromolecular composition of cells and tissues, in order to characterize biological systems in health and disease. We discuss the general problem of detection specificity and present the approach our group has taken, involving the reformatting of analogue biological information to digital reporter segments of genetic information via a series of DNA ligation assays. The assays enable extensive, coordinated analyses of the numbers and locations of genes, transcripts and protein.
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| 9. |
- Malm, Anna, 1979-, et al.
(författare)
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Production Start-up Phase : A Comparison between New Product Development and Production Relocation
- 2012
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- A challenging situation due to a more global market is the increasing need for production relocation. New product development with constant increasing competition challenges the ways to perform production start-up and production relocation. Product development processes focus in general on function of the product and to avoid product quality problems. Production relocation processes also focus on avoiding product quality problems, but problems that occur within production relocation are mostly related to forgotten or misunderstood information. In this paper, a literature review is performed investigating these three areas and relate them to industrial experience. Existing relocation processes are often based on processes for product development. There are several similarities between the production start-up in product development and product relocation since the same result is requested. However, the way to achieve the results can differ within the literature, within the paper are the differences and similarities discussed.
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| 10. |
- McGinn, Steven, et al.
(författare)
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New Technologies for DNA analysis-A review of the READNA Project.
- 2016
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Ingår i: New Biotechnology. - : Elsevier BV. - 1876-4347 .- 1871-6784.
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Forskningsöversikt (refereegranskat)abstract
- The REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received funding from the European Commission for 4 1/2 years. The objectives of the project revolved around technological developments in nucleic acid analysis. The project partners have discovered, created and developed a huge body of insights into nucleic acid analysis, ranging from improvements and implementation of current technologies to the most promising sequencing technologies that constitute a 3(rd) and 4(th) generation of sequencing methods with nanopores and in situ sequencing, respectively.
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| 11. |
- Michelgård, Åsa, et al.
(författare)
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Symptom provocation in specific phobia affects the substance P neurokinin-1 receptor systems
- 2007
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Ingår i: Biological Psychiatry. - : Elsevier BV. - 0006-3223 .- 1873-2402. ; 61:8, s. 1002-1006
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Tidskriftsartikel (refereegranskat)abstract
- Background: Animal studies demonstrate that stress and negative affect enhance the release of the neuropeptide substance P (SP), which binds to the neurokinin 1 (NK1) receptor. This positron emission tomography (PET) study evaluated how the activity in the SP-NK1 receptor system in the amygdala was affected by fear provocation in subjects with specific phobia. Methods: Sixteen adult women with DSM-IV-defined specific phobia for either snakes or spiders but not both viewed pictures of feared and non-feared animals while being PET-scanned for 60 min with the highly specific NK1 receptor antagonist [11C]GR205171 as the labeled PET tracer. Results: The uptake of the labeled NK1 receptor antagonist was significantly reduced in the right amygdala during phobic stimulation. In the left amygdala no significant differences were found between phobic and non-phobic conditions. There was a negative correlation in the right, but not left, amygdala between subjective anxiety ratings and NK1 tracer binding. Conclusions: Fear provocation affects the SP-NK1 receptor system in the right amygdala. This reflects reduced NK1 receptor availability during fear and could mirror an increased release of endogenous substance P.
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| 12. |
- Spetz, Anna-Clara, 1973-, et al.
(författare)
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Testosterone correlated to symptoms of partial androgen deficiency in aging men (PADAM) in an elderly Swedish population
- 2007
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Ingår i: Menopause. - : Ovid Technologies (Wolters Kluwer Health). - 1072-3714 .- 1530-0374. ; 14:6, s. 999-1005
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To investigate the prevalence of different symptoms of partial androgen deficiency in aging men (PADAM) and to correlate them with blood concentrations of testosterone and bioavailable testosterone. DESIGN: A total of 370 men, aged 55 to 75 years, were invited to one of three primary healthcare centers in Sweden. They were asked to complete a questionnaire regarding demographic data, medical history, mood status, medication, castration therapy and smoking, exercise and alcohol habits, as well as different symptoms of PADAM. The 10 questions from a previously used questionnaire (the ADAM questionnaire) were included. The men were offered blood tests for analyses of testosterone, follicle stimulating hormone, luteinizing hormone, steroid hormone-binding globulin, and albumin. From these test results, we calculated the bioavailable testosterone. RESULTS: Of the questionnaires sent out, 81.6% were returned and eligible for evaluation. Blood samples were obtained from 85.8% of men answering the questionnaire. Many of the symptoms, including five from the ADAM questionnaire, were more common in older age groups (P < 0.05). Three symptoms, deterioration in work performance, decreased strength and/or endurance, and bothersome hot flushes, were associated with low bioavailable testosterone and/or testosterone (P < 0.05). Testosterone and bioavailable testosterone did not differ between age groups, but bioavailable testosterone was higher in men with three or fewer symptoms on the ADAM questionnaire. CONCLUSIONS: Symptoms associated with PADAM often occur in an elderly population, but we could only find an association between three symptoms and blood testosterone concentrations, one being bothersome hot flushes. It is likely that these symptoms have a more complex background than only PADAM. ©2007The North American Menopause Society.
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| 13. |
- Zaborowska, Ewa, et al.
(författare)
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Effects of acupuncture, applied relaxation, estrogens and placebo on hot flushes in postmenopausal women – an analysis of two prospective, parallel, randomised studies
- 2007
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Ingår i: Climacteric. - : Climacteric. - 1369-7137 .- 1473-0804. ; 10:1, s. 38-45
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To assess if transdermal or oral estrogens, acupuncture and applied relaxation decrease the number of menopausal hot flushes/24 h and improve climacteric symptoms, as assessed by the Kupperman index, more than transdermal placebo treatment. Setting: An outpatient clinic at a Swedish university hospital. Methods: A total of 102 postmenopausal women were recruited to two studies performed in parallel. In Study I, the women were randomized between transdermal placebo or estrogen treatment and, in Study II, between oral estrogens, acupuncture or applied relaxation for 12 weeks. Climacteric symptoms were measured with daily logbooks on hot flushes. Women completed the assessment questionnaire for the Kupperman index at baseline and after 12 weeks. Results: The number of flushes/24 h decreased significantly after 4 and 12 weeks in all groups except the placebo group. Both at 4 and 12 weeks, acupuncture decreased the number of flushes more (p < 0.05; p < 0.01, respectively) than placebo. At 12 weeks, applied relaxation decreased the number of flushes more (p < 0.05) than placebo. The Kupperman index score decreased in all groups except the placebo group. The decrease in score was significantly greater in all treatment groups than in the placebo group (p < 0.01). Conclusion: Acupuncture and applied relaxation both reduced the number of hot flushes significantly better than placebo and should be further evaluated as alternatives to hormone therapy in women with menopausal vasomotor complaints.
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| 14. |
- Aarnio, Mikko, et al.
(författare)
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Visualization of painful inflammation in patients with pain after traumatic ankle sprain using [(11)C]-D-deprenyl PET/CT.
- 2017
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Ingår i: Scandinavian Journal of Pain. - : Walter de Gruyter. - 1877-8860 .- 1877-8879. ; 17:1, s. 418-424
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND AND AIMS: Positron emission tomography (PET) with the radioligand [(11)C]-D-deprenyl has shown increased signal at location of pain in patients with rheumatoid arthritis and chronic whiplash injury. The binding site of [(11)C]-D-deprenyl in peripheral tissues is suggested to be mitochondrial monoamine oxidase in cells engaged in post-traumatic inflammation and tissue repair processes. The association between [(11)C]-D-deprenyl uptake and the transition from acute to chronic pain remain unknown. Further imaging studies of musculoskeletal pain at the molecular level would benefit from establishing a clinical model in a common and well-defined injury in otherwise healthy and drug-naïve subjects. The aim of this study was to investigate if [(11)C]-D-deprenyl uptake would be acutely elevated in unilateral ankle sprain and if tracer uptake would be reduced as a function of healing, and correlated with pain localizations and pain experience.METHODS: Eight otherwise healthy patients with unilateral ankle sprain were recruited at the emergency department. All underwent [(11)C]-D-deprenyl PET/CT in the acute phase, at one month and 6-14 months after injury.RESULTS: Acute [(11)C]-D-deprenyl uptake at the injury site was a factor of 10.7 (range 2.9-37.3) higher than the intact ankle. During healing, [(11)C]-D-deprenyl uptake decreased, but did not normalize until after 11 months. Patients experiencing persistent pain had prolonged [(11)C]-D-deprenyl uptake in painful locations.CONCLUSIONS AND IMPLICATIONS: The data provide further support that [(11)C]-D-deprenyl PET can visualize, quantify and follow processes in peripheral tissue that may relate to soft tissue injuries, inflammation and associated nociceptive signaling. Such an objective correlate would represent a progress in pain research, as well as in clinical pain diagnostics and management.
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| 15. |
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| 16. |
- Ahmadi, Ahmad, 1964-, et al.
(författare)
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GSTM1 and mEPHX polymorphisms in Parkinson's disease and age of onset
- 2000
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Ingår i: Biochemical and Biophysical Research Communications - BBRC. - : Elsevier BV. - 0006-291X .- 1090-2104. ; 269:3, s. 676-680
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Tidskriftsartikel (refereegranskat)abstract
- Both environmental and genetic factors are involved in the development of PD and biotransformation of exogenous and endogenous compounds and may play a role in inter-individual susceptibility. Therefore, we investigated the presence of null genotypes of GSTM1, GSTT1, and two polymorphisms of mEPHX in subjects with Parkinson's disease and in a reference population. The study included 35 male PD patients and a male control group including 283 subjects. Homozygosity of the histidine (H) 113 isoform of mEPHX was significantly increased in PD patients (odds ratio = 3.8 CI 95% 1.2–11.8) and analysis of allele frequencies displayed an increased frequency of the H-allele among PD patients (odds ratio = 1.9 CI 95% 1.1–3.3). However, a significantly elevated median age for the onset of PD was found among GSTM1 gene carriers (median age = 68 years) compared to PD patients being GSTM1 null genotypes (median age = 57 years). Our observations suggest that (H) 113 isoform of mEPHX, which has been suggested as a low activity isoform, is overrepresented in PD patients and that inherited carriers of the GSTM1 gene postpone the onset of PD. These detoxification pathways may represent important protective mechanisms against reactive intermediates modifying the susceptibility and onset of PD.
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| 17. |
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| 18. |
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| 19. |
- Andersson, Therese M. -L., et al.
(författare)
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Cancer during pregnancy and the postpartum period : A population-based study
- 2015
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Ingår i: Cancer. - : Wiley. - 0008-543X .- 1097-0142. ; 121:12, s. 2072-2077
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUNDThe purpose of this study was to assess patterns of cancer occurrence during pregnancy and the postpartum period. METHODSThis was a register-based study using data from the Swedish Multi-Generation Register and the National Cancer Register from 1963 to 2007. Pregnancy-associated cancer (PAC) was defined as a malignancy detected during pregnancy or within 2 years of delivery and was assessed in 7 time windows: pregnancy, trimesters 1-3, 0-6 months, 7-12 months, and second year postpartum. Population incidence rates by 5-year age groups and periods were used to estimate the expected number of PACs for each site. The observed versus the expected (O/E) number of cases was estimated with 95% confidence intervals (CI). RESULTSThe 3 most common malignancies during pregnancy were melanoma (n=232), breast (n=139) and cervical cancer (n=139). With a slightly different rank order, these cancers are also the most common in women of childbearing age. The number of observed cases during pregnancy was lower than expected for all cancers, with a combined O/E ratio for all sites of 0.46 (95% CI, 0.43-0.49). The O/E ratio was close to 1 during all postpartum intervals, including 0-6 months (0.93; 95% CI, 0.88-0.98), 7-12 months (0.96; 95% CI, 0.91-1.01), and during the second year after delivery (0.95; 95% CI, 0.92-0.99). CONCLUSIONSThe rate of cancer during pregnancy was lower than expected for all sites, a finding that could not be explained entirely by delayed diagnosis. A rebound in the number of observed cases after delivery was restricted to melanoma, nervous system malignancies, and breast and thyroid cancer. Cancer 2015;121:2072-2077. (c) 2015 American Cancer Society. Fewer cancers than expected are found during pregnancy, a finding that cannot be explained entirely by delayed diagnosis.
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| 20. |
- Badasjane, Viktorija
(författare)
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Coordinating Digital Transformation in International Manufacturing Networks
- 2023
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Manufacturing companies have adapted to globalisation and collected their globally dispersed factories into factory networks, known as international manufacturing networks (IMNs). This requires coordination to access the associated competitive advantages, synchronise the factories, and exploit the capabilities inherent in those individual factories. However, when IMNs introduce digital transformation into the factories, the coordination is often hindered by uncertainty and complexity, as digital transformation requires an extensive adjustment that affects everything from the organisational structure to ways of working. Different parts of the network that are dependent on one another, for example, may be difficult to track and foresee the consequences of digital transformation. Hence, due to the respective challenges, complexities, and uncertainties, the coordination of digital transformation in IMN is paramount to examine. This licentiate thesis begins with exploring coordination mechanisms to increase the understanding of existing research and shape it into a comprehensive overview. Moreover, through case studies, this thesis explores the challenges in and enablers for coordinating digital transformation in IMNs. Altogether, the challenges and enablers are analysed within the dimensions and categories of coordination mechanisms, i.e., they are collected into an overview and described within the case study context. The most significant findings of this thesis are related to the organisational structure, which enables the coordination of digital transformation. However, plenty of challenges remain, foremost connected to the formalisation of the organisational structure, e.g., balancing the rules and guidelines for digital transformation but providing space for people performing the activities to explore and investigate digital technologies. This thesis further contributes to the existing body of research by untangling the complexity of coordination itself and, specifically, the coordination of digital transformation in IMNs, explicitly adding to the operations management field and the management of global operations. Practical contributions are also made, i.e., this thesis promotes practitioners’ increased understanding by providing specific examples and descriptions of the findings within their context. Based on the findings, this thesis offers multiple paths for future research, keeping in mind that coordination is not static but evolving, depending on the context in which it is performed.
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| 21. |
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| 22. |
- Bengtsson, Ylva, et al.
(författare)
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Ulriksdals slott under 350 år
- 1995
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Rapport (populärvet., debatt m.m.)abstract
- Studierna har utgått från Ulriksdals slott, uppfört av Jacob De la Gardie för 350 år sedan. Som kungligt slott har Ulriksdal genomgått ombyggnader under 1600 - och 1700-talet, men präglas idag mest av Karl XVs omfattande omdaning på 1850-talet och Gustav VI Adolfs lika genomgripande förändringar på 1920-talet.Slottet har bjudit på rika studiemöjligheter av stilideal, planlösning, interiörgestaltning, snickerikultur och stormtekniska system från hela 350-årsperioden. Genom noggranna uppmätningar och inventeringar på plats kopplade till arkivstudier har slottets komplicerade förändringshistoria kunnat analyseras,
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| 23. |
- Berden, Michael, et al.
(författare)
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Smart Construction logistics
- 2018
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The growth in urban population and economic upturn is leading to higher demand for construction, repair and renovation works in cities. Houses, public utilities, retail spaces, offices and infrastructure need to adapt to cope with the increasing number of residents and visitors, urban functions and changing standards. Construction projects contribute to more attractive, sustainable and economically viable urban areas once they are finished. However, transport activities related to construction works have negative impacts on the surrounding community if not handled appropriately. It is estimated that 15 to 20 percent of heavy goods vehicles in cities are related to construction, and 30 to 40 percent of light commercial vans [1]. In the cities studied in the CIVIC project, construction-related transport was found to be one of the biggest challenges to improving sustainability. Smarter, cleaner and safer construction logistics solutions in urban areas are needed for environmental, societal and economic reasons. However, in many European cities and metropolitan areas the sense of urgency is not evident or a lack of knowledge is creating passivity. The goal of the CIVIC project is to facilitate and support efficient, sustainable and broadly endorsed transport to, from and around urban construction sites that minimises disruption in the surrounding community, improves construction productivity and optimises energy efficiency. The CIVIC project found that the impact of construction works on mobility and livability of a city was only a very limited part of the urban planning in the cities studied: Amsterdam, Vienna, Brussels, Stockholm and Gothenburg. The studied cities focused on large-scale infrastructure projects such as building motorways, railway stations and underground train systems or development projects, for example, whole new city areas. It is not only these large projects that need to be considered focusing on the impact of construction related transports. Additionally, there are many small-scale development projects in cities with a combination of different official and private actors. Contractors and developers/clients are displaying increasing interest in construction logistics since research shows that improved construction logistics can improve the productivity of a construction project by about 30 percent. Construction companies using innovative logistics concepts see less congestion around the sites and improved productivity and road safety. Thus, there is a need to align public planning coordinating construction projects with traffic planning in order to manage city infrastructure bottlenecks. The ultimate goal is coordinated planning between the public partner of construction projects and the private construction contractors and developers on the necessary measures for mobility, livability and road safety in the city. This handbook has been developed for local governments, clients, developers, contractors, or any other actor that can influence logistics planning and the setup of construction projects. It can help local governments collaborating with private partners to realise more sustainable, and safer, construction works with less inconvenience and cleaner air. In addition, it can help clients, developers and contractors to ensure smooth and efficient construction operations. Hence, sustainable construction logistics could be a future deal-breaker. The handbook first provides a description of the challenges of urban construction logistics and the governance of construction logistics. Secondly, it presents the Smart Governance Concept developed under the CIVIC project, combining different tools to improve construction logistics and its governance. This concept can be applied on two levels: the city level and the project level. On a city level, a sense of shared ownership and urgency should be created to optimise construction logistics on the project level. This is the first step of the concept. Steps 2 to 6 outline different tools and methods for the development of a solution: in step 2, a conceptual solution is required to create a common understanding of the prerequisites for the specific project and possible methods for organising logistics. Step 3 entails the different instruments, policies and guidelines that are needed for creating the formal conditions for the solution. In step 4, the specific stakeholders are involved to identify important criteria that influence the selection of the final solution. Step 5 then aims to select the final solution by providing cost calculations and traffic optimisation models. Step 6 entails the collection of data and follow-ups of KPIs. The final step 7 regards the evaluation of the different projects that feed back into the continuous development process of the optimisation of construction logistics at a city level. This final step is presented together with step 1 since these both concern the city level. The Smart Governance Concept should be part of development/construction projects from the very beginning, meaning from the planning phase.
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| 24. |
- Bergström, Karl, et al.
(författare)
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The MIMIC construction logistics game : facilitating group discussion and understanding of construction logistics through gameplay
- 2020
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Ingår i: IOP Conf. Series: Earth and Environmental Science.
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Konferensbidrag (refereegranskat)abstract
- The aim of this study is to describe the development of an innovative planning tool to promote the knowledge and collaboration needed to overcome challenges in the sanitation sector. A serious game was designed to share knowledge about resource recovery and support attitude-change and collaboration between stakeholders. This study documents the co-design process of game development from conception based on a set of specifications the game should achieve, through iterative testing with relevant stakeholders as players. The resulting prototype of the game showed that it was not possible to include all the original desired specifications in the final game. Stakeholders found that the game was engaging, stimulated creativity and achieved its goal.
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| 25. |
- Bergström, Karl, 1980, et al.
(författare)
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The MIMIC construction logistics game: facilitating group discussion and understanding of construction logistics through gameplay
- 2020
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Ingår i: IOP Conference Series: Earth and Environmental Science. - : IOP Publishing. - 1755-1307 .- 1755-1315. ; 588:1.15 – 1.19
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Konferensbidrag (refereegranskat)abstract
- n order to facilitate discussion on construction logistic solutions in both homogenous and heterogeneous groups, the MIMIC CLS game has been developed, that allows players to negotiate transport routes and common logistics solutions surrounding an abstract construction area. Through game mechanics specially chosen to create appropriate friction between the players, discussion on the topics of the game is stimulated. The design process included significant amounts of testing and provided two key insights: the manner in which specific game design patterns influenced the game's purpose, and the difficulties involved in creating, playing and presenting games for a target group with little or no experience of games. It was also evident that a designated game facilitator made it possible to further reinforce the impact of the game, and likely necessary to be able to use it in an appropriate timeframe. Future venues of work include the integration of the game and subsequent discussions into an overall workshop format.
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