| 1. |
- Shungin, Dmitry, et al.
(författare)
-
New genetic loci link adipose and insulin biology to body fat distribution.
- 2015
-
Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 518:7538, s. 187-378
-
Tidskriftsartikel (refereegranskat)abstract
- Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.
|
|
| 2. |
- Akande, T., et al.
(författare)
-
Conclusions and a Look Ahead.
- 2005
-
Ingår i: The African Food Crisis: Lessons from the Asian Green Revolution. - 0851999980 ; , s. 253-260
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)
|
|
| 3. |
- Billgren, Charlotte, et al.
(författare)
-
Approaching Reality : Comparing Stakeholder Analysis and Cultural Theory in the Context of Natural Resource Management
- 2008
-
Ingår i: Land use policy. - : Elsevier BV. - 0264-8377 .- 1873-5754. ; 25:4, s. 550-562
-
Tidskriftsartikel (refereegranskat)abstract
- Increased pressure on ecosystems and enhanced competition over the use of natural resources makes it necessary to develop sustainable methods for natural resource management (NRM). However, NRM is a complicated issue. It involves numerous stakeholders, with different needs, resources and perceptions of nature. Stakeholder participation will necessarily be selective, based both on theoretical assumptions about who is a legitimate stakeholder and unevenly distributed power among stakeholders. Although stakeholder involvement is important, sometimes the theory appears to be rather blunt. It has been suggested that, since different categories of stakeholders embody different perceptions of nature, cultural theory could provide important additional criteria for stakeholder involvement. Based on field studies in Naivasha, Kenya, this paper analyses pros and cons of stakeholder analysis and investigates the usefulness of cultural theory for improved stakeholder analysis.
|
|
| 4. |
|
|
| 5. |
- Billgren, Charlotte, 1979-
(författare)
-
Making Sense of Environmental Values : Wetlands in Kenya
- 2008
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- En av de viktigaste frågorna i världen idag är naturresurshantering. Med en väx-ande befolkning och hoten från klimatförändringar kommer förvaltningen av jordens naturresurser bli än viktigare, såväl för dagens generation som kommande generationer. En viktig aspekt när det gäller naturresurshantering är hur människor uppfattar och värderar naturen. För att komma närmare dessa miljövärden har ett flertal olika vetenskapliga tillvägagångssätt föreslagits. Den här avhandlingen undersöker hur det är möjligt att närma sig miljövärden under olika omständighe-ter och utifrån olika behov. Detta görs genom att undersöka hur olika teorier har använts, och kan användas, avseende olika våtmarker i Kenya. I utvecklingslän-der har naturresurser, teoretiskt sett, ett högre värde eftersom fattiga människor till en högre grad är direkt beroende av naturresurser och ekosystemtjänster. Ut-gångspunkten i denna avhandling är sex våtmarksområden i Kenya under olika förvaltning och med ett flertal, både aktuella och potentiella, användare. I av-handlingen undersöks hur lokalsamhället, myndigheter, industrier och turister uppfattar och värderar våtmarkerna. Genom att applicera ett arenaperspektiv, som betonar vikten av tvärvetenskap, diskuteras i avhandlingen det ekonomiska värdet av miljön för att sedan applicera andra metoder såsom emergy analys, stakeholder analys, kulturteori och riskanalys för att bredda och berika värderingen av miljön.
|
|
| 6. |
- Djurfeldt, Göran, et al.
(författare)
-
Addressing Food Crisis in Africa.
- 2007
-
Ingår i: Ökonomisk utvikling, landbruk och bistand. ; , s. 39-44
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)
|
|
| 7. |
|
|
| 8. |
- Djurfeldt, Göran, et al.
(författare)
-
African Food Crisis - The Relevance of Asean Experiences.
- 2005
-
Ingår i: The African Food Crisis - Lessons from the Asean Green revolution.. - Wallingford : CABI Publishing. - 0851999980 - 9780851999982 ; , s. -265
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Why can Asia now feed its rapidly growing population, but Africa continues to experience famine? This book is the outcome of a three-year project coordinated by a group of Swedish researchers with collaborating scholars from Africa and Asia. It provides a comparative study between Asian agricultural development during the Green Revolution in food production and the current problematic agricultural situation in sub-Saharan Africa. Based on case studies of eight African and eight Asian countries (focusing on the early part of the Green Revolution), this book presents a causal and explanatory model of Asian green revolutions. It discusses why such progress has been made in Asia, but has not yet occurred in Africa. It also examines the implications of the case studies for future development in Africa.
|
|
| 9. |
|
|
| 10. |
|
|
| 11. |
- Djurfeldt, Göran, et al.
(författare)
-
Afrikas vernachlässigte Bauern.
- 2006
-
Ingår i: Entwicklung und Zusammenarbeit. ; Nr 3, März, s. 130-130
-
Tidskriftsartikel (populärvet., debatt m.m.)
|
|
| 12. |
- Djurfeldt, Göran, et al.
(författare)
-
Afrint database
- 2011
-
Annan publikation (övrigt vetenskapligt/konstnärligt)
|
|
| 13. |
- Djurfeldt, Göran, et al.
(författare)
-
Dubbelmoral om Afrika
- 2005
-
Ingår i: Sydsvenskan. - 1652-814X.
-
Tidskriftsartikel (populärvet., debatt m.m.)
|
|
| 14. |
|
|
| 15. |
|
|
| 16. |
|
|
| 17. |
|
|
| 18. |
- Gaulton, Kyle J, et al.
(författare)
-
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
- 2015
-
Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 47:12, s. 1415-1415
-
Tidskriftsartikel (refereegranskat)abstract
- We performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry. We identified 49 distinct association signals at these loci, including five mapping in or near KCNQ1. 'Credible sets' of the variants most likely to drive each distinct signal mapped predominantly to noncoding sequence, implying that association with T2D is mediated through gene regulation. Credible set variants were enriched for overlap with FOXA2 chromatin immunoprecipitation binding sites in human islet and liver cells, including at MTNR1B, where fine mapping implicated rs10830963 as driving T2D association. We confirmed that the T2D risk allele for this SNP increases FOXA2-bound enhancer activity in islet- and liver-derived cells. We observed allele-specific differences in NEUROD1 binding in islet-derived cells, consistent with evidence that the T2D risk allele increases islet MTNR1B expression. Our study demonstrates how integration of genetic and genomic information can define molecular mechanisms through which variants underlying association signals exert their effects on disease.
|
|
| 19. |
- Hatti, Neelambar, et al.
(författare)
-
Cooperatives as Instruments of Rural development
- 1994
-
Ingår i: Ground Level Development : NGOs, Co-operatives and Local Organizations in the Third World - NGOs, Co-operatives and Local Organizations in the Third World. - 1400-1144. - 9179662951 ; :56, s. 63-82
-
Bokkapitel (refereegranskat)
|
|
| 20. |
|
|
| 21. |
- Holmén, Hans, 1948-, et al.
(författare)
-
Addressing Food Crisis in Africa. : what can sub-Saharan Africa learn from Asian experiences in addressing its food crisis?
- 2005
-
Ingår i: Ökonomisk utvikling, landbrug og bistand.. - Oslo : Norges Bondelag og Norsk Landbrukssamvirke. ; , s. 39-44
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- What can sub-Saharan Africa learn from Asian experiences in addressing its food crisis? / Historical and comparative study of agricultural development in seven Asian countries. Comparison of African case studies in eight countries in SSA: macro studies based on secondary data and interviews with key persons and, to complement this, village surveys and questionnaires involving more than 3000 smallholders. The performance of African smallholders is held back by a number of economic, political and institutional factors at regional, national and international levels. Positive tone: it is indeed possible to reverse the downhill slide with regard to the food situation in SSA by means of policy measures on the parts of African governments and by the international community.
|
|
| 22. |
- Holmén, Hans, 1948-, et al.
(författare)
-
African Agriculture: from Crisis to Development?
- 2010
-
Ingår i: African Smallholders. - Wallingford : CABI International. - 978 1 84593 716 4 ; , s. 23-44
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Based on highly topical international research in a high-priority area, this book documents the farm-level effects of the reorientation of agricultural policies with different themes for the different countries such as micro-credit, infrastructure, cash crop production and food security. It discusses staple food production in sub-Saharan Africa and its response to changing geo-political, macro-economic and agricultural policy, to deepen our understanding of how agricultural development unfolds at farm level. It is a useful resource for all those researching or involved with food security, agri.
|
|
| 23. |
- Holmén, Hans, 1948-, et al.
(författare)
-
Africa's Food Crisis -- Does Asia's green revolution offer any lessons?
- 2008
-
Ingår i: Agriculture, Trade and Development -- Towards a greater coherence.. - Stockholm : KSLA. ; , s. 73-86
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The overwhelming majority of people living in poverty are small-scale farmers and agricultural workers. To reach the UN Millennium Development Goals of halving world poverty by 2015, agricultural development and enhanced productivity must play a key role.Taking Sweden’s ”Policy for Global Development” as the point of departure, the purpose of this book is to highlight linkages and conflicts of interest between the developed and developing countries in agriculture, trade and environmental management, as well as the potential for enhanced coherence.
|
|
| 24. |
- Holmén, Hans, 1948-, et al.
(författare)
-
Afrikas gröna revolution kom av sig.
- 2006
-
Ingår i: Forskning & framsteg. ; Nr 3, April, s. 52-57
-
Tidskriftsartikel (populärvet., debatt m.m.)
|
|
| 25. |
|
|
