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Enumeration	Reference	Cover	Find
1.	2017 swepub:Mat__t
2.	Weinstein, John N., et al. (author) The cancer genome atlas pan-cancer analysis project 2013 In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 45:10, s. 1113-1120 Research review (peer-reviewed)abstract The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile. © 2013 Nature America, Inc. All rights reserved.
3.	Rhind, Nicholas, et al. (author) Comparative Functional Genomics of the Fission Yeasts 2011 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 332:6032, s. 930-936 Journal article (peer-reviewed)abstract The fission yeast clade-comprising Schizosaccharomyces pombe, S. octosporus, S. cryophilus, and S. japonicus-occupies the basal branch of Ascomycete fungi and is an important model of eukaryote biology. A comparative annotation of these genomes identified a near extinction of transposons and the associated innovation of transposon-free centromeres. Expression analysis established that meiotic genes are subject to antisense transcription during vegetative growth, which suggests a mechanism for their tight regulation. In addition, trans-acting regulators control new genes within the context of expanded functional modules for meiosis and stress response. Differences in gene content and regulation also explain why, unlike the budding yeast of Saccharomycotina, fission yeasts cannot use ethanol as a primary carbon source. These analyses elucidate the genome structure and gene regulation of fission yeast and provide tools for investigation across the Schizosaccharomyces clade.

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Type of publication: journal article (1); research review (1)

Type of content: peer-reviewed (2)

Author/Editor: Yang, Yang (1); Chen, C. (1); Chen, S. (1); Chen, X. (1); Chen, Y. (1); Deluca, C. (1); show more...; Endo, M. (1); Garcia, C. (1); Hayashi, T. (1); Hirose, M. (1); Hu, D. (1); Jackson, M. (1); Kim, H. (1); Kobayashi, T. (1); Li, B. (1); Li, L. (1); Liu, B. (1); Liu, D. (1); Liu, L. (1); Nakamura, T. (1); Ninomiya, Y. (1); Okumura, Y. (1); Sanchez, J. (1); Sasaki, Y. (1); Shimizu, S. (1); Sun, X. (1); Suzuki, Y. (1); Takahashi, Y. (1); Tanaka, S. (1); Vogel, M. (1); Wang, C. (1); Wang, F. (1); Wang, R. (1); Wu, X. (1); Yamamoto, S. (1); Yang, H. (1); Yang, Y. (1); Zhang, J. (1); Zhu, J. (1); Zhu, Y. (1); Kim, Y. (1); Zhang, R. (1); Zhao, Y. (1); Banerjee, P. (1); Gosselink, M. (1); Kanno, T. (1); Watanabe, I. (1); Gonzalez, S. (1); Suzuki, S (1); Banerjee, S. (1); show less...

University: Karolinska Institutet (2); University of Gothenburg (1); Södertörn University (1); Chalmers University of Technology (1)

Language: English (3)

Research subject (UKÄ/SCB): Natural sciences (2); Medical and Health Sciences (1)

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