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- Isaksen, K, et al.
(författare)
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Recent warming of mountain permafrost in Svalbard and Scandinavia
- 2007
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Ingår i: Journal of Geophysical Research: Earth Surface. ; 112:F2, s. F02S04-
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Tidskriftsartikel (refereegranskat)abstract
- Three deep boreholes (>= 100 m) in mountain permafrost were recently drilled in Svalbard (Janssonhaugen) and in Scandinavia (Tarfalaryggen and Juvvasshoe) for long-term permafrost monitoring. These holes form part of a latitudinal transect of boreholes in permafrost through Europe, established by the Permafrost and Climate in Europe (PACE) project. Six-year thermal time series data collected from the three boreholes are presented. These data provide the first opportunity for temporal trends in permafrost temperatures in Svalbard and Scandinavia to be analyzed. Results show that the permafrost has warmed considerably at all three sites. Significant warming is detectable down to at least 60 m depth, and present decadal warming rates at the permafrost surface are on the order of 0.04 degrees-0.07 degrees C yr(-1), with greatest warming in Svalbard and in northern Scandinavia. The present regional trend shows accelerated warming during the last decade.
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| 3. |
- Young, WJ, et al.
(författare)
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Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease
- 2023
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Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 14:1, s. 1411-
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Tidskriftsartikel (refereegranskat)abstract
- The 3-dimensional spatial and 2-dimensional frontal QRS-T angles are measures derived from the vectorcardiogram. They are independent risk predictors for arrhythmia, but the underlying biology is unknown. Using multi-ancestry genome-wide association studies we identify 61 (58 previously unreported) loci for the spatial QRS-T angle (N = 118,780) and 11 for the frontal QRS-T angle (N = 159,715). Seven out of the 61 spatial QRS-T angle loci have not been reported for other electrocardiographic measures. Enrichments are observed in pathways related to cardiac and vascular development, muscle contraction, and hypertrophy. Pairwise genome-wide association studies with classical ECG traits identify shared genetic influences with PR interval and QRS duration. Phenome-wide scanning indicate associations with atrial fibrillation, atrioventricular block and arterial embolism and genetically determined QRS-T angle measures are associated with fascicular and bundle branch block (and also atrioventricular block for the frontal QRS-T angle). We identify potential biology involved in the QRS-T angle and their genetic relationships with cardiovascular traits and diseases, may inform future research and risk prediction.
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