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- Brink Pinto, Andrés, et al.
(författare)
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Inledning
- 2022
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Ingår i: Kritiska blickar från marginalen : Reflektioner i spåren av Jens Rydström - Reflektioner i spåren av Jens Rydström. - : Department of Gender Studies, Lund University. - 9789180392938 - 9789180392945 ; , s. 11-22
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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- Alfredsson, Eva C., et al.
(författare)
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Industrial climate mitigation strategies and the remaining fair carbon budget – The case of Sweden
- 2024
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Ingår i: Next Sustainability. - 2949-8236. ; 3, s. 100031-100031
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Tidskriftsartikel (refereegranskat)abstract
- This article explores the climate mitigation strategies of the 15 industries with the largest carbon dioxide emissions in Sweden. Starting from two carbon budget alternatives, we analyse the mitigation projections of the companies in relation to what can be considered their fair share of the remaining carbon budget for Sweden.We furthermore determine the uncertainties associated with the strategies. The results suggest that if the communicated mitigation plans are implemented as planned, the companies overdraft our main, 1.5-degree, budget option but stay within the alternative 1.7-degree budget. The analysis shows, however, that the timing and efficiency of emission reductions are crucial.Already small delays or lower efficiency in implementation, result in evident overdrafts of also the alternative budget. There are also substantial political and technical risks which can prevent timely mitigations. The article makes a novel contribution by analyzing industries’ mitigation strategies relative to their share of the remaining carbon budget.The article demonstrates the importance of transparent industrial climate mitigation strategies and in particular the need for policymakers to set incentive structures to promote strategy implementation.
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| 7. |
- Alfredsson, Eva, 1963-, et al.
(författare)
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Investeringar för en rättvis klimatomställning
- 2023
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Annan publikation (populärvet., debatt m.m.)abstract
- Inom forskningsprogrammet FAIRTRANS har en workshop hållits om investeringars roll i klimatomställningen. Syftet var att lyfta fram olika gruppers behov av investeringar för en rättvis fossilfri framtid inom ramen för en svensk koldioxidbudget.
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| 8. |
- Alfredsson, Eva, 1963-, et al.
(författare)
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Investeringars betydelse för klimatomställningen
- 2023
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Rapport (populärvet., debatt m.m.)abstract
- Syftet med detta kunskapsunderlag är att förbereda för deltagande och dialog inför FAIRTRANS Workshop 2. Fokus för diskussionen är vilka investeringar som bör prioriteras för att Sverige ska nå en rättvis koldioxidbudget.
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- Bjoreland, Anders, et al.
(författare)
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Liquid ionization chamber calibrated gel dosimetry in conformal stereotactic radiotherapy of brain lesions
- 2008
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Ingår i: Acta Oncologica. - : Informa UK Limited. - 1651-226X .- 0284-186X. ; 47:6, s. 1099-1109
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Tidskriftsartikel (refereegranskat)abstract
- Hypofractionated conformal stereotactic radiotherapy (HCSRT) is an established method of treating brain lesions such as arteriovenous malformations (AVMs) and brain metastases. The aim of this study was to investigate the reliability of treatment plans in the terms of dose distribution and absorbed dose for HCSRT. Methods and materials. Treatment plans for three different clinical intracerebral targets, AVMs, were transferred to a CT study of a spherical water filled phantom simulating the human head and recalculated for the phantom geometry using a standard treatment planning system utilizing a pencil beam algorithm for dose calculation. The calculated absorbed dose, relative three dimensional (3D) dose distribution and dose conformity were investigated using gel dosimetry normalized to liquid ionization chamber (LIC) measurements. Results. The measured absorbed dose to the dose reference point was found to be within 2% of the calculated dose for all three targets. The measured dose distribution was found to be within 3% and 2 mm of the calculated dose for more than 93% of all points in the target volume for all three targets. Conclusions. The results show that the investigated standard treatment planning system can correctly predict the absorbed dose and dose distribution in different types of intracerebral targets and that the treatment can be delivered according to the plan.
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- Blomquist, M, et al.
(författare)
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Multileaf collimation of electrons-clinical effects on electron energy modulation and mixed beam therapy depending on treatment head design
- 2002
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Ingår i: Physics in Medicine and Biology. - 0031-9155 .- 1361-6560. ; 47:7, s. 1013-1024
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Tidskriftsartikel (refereegranskat)abstract
- The aim Of this Study was to explore the possibilities of using multileaf-collimated electron beams for advanced radiation therapy with conventional scattering foil flattened beams. Monte Carlo simulations were performed with the aim to improve electron beam characteristics and enable isocentric multileaf collimation. The scattering foil positions, monitor chamber thickness, the MLC location and the amount of He in the treatment head were optimized for three common commercial accelerators. The performance of the three optimized treatment head designs was compared for different SSDs in air. at treatment depth in water and for some clinical cases. The effects of electron/photon beam matching including generalized random and static errors using Gaussian one-dimensional (1D) error distributions, and also electron energy modulation, were studied at treatment depth in beater, The modification of the treatment heads improved the electron beam characteristics and enabled the use of multileaf collimation in isocentric delivery of both electron and photon beams in a mixed beam IMRT procedure.
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- Broberg, Martin, et al.
(författare)
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Comparative genomics highlights the importance of drug efflux transporters during evolution of mycoparasitism in Clonostachys subgenus Bionectria (Fungi, Ascomycota, Hypocreales)
- 2021
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Ingår i: Evolutionary applications. - : Wiley. - 1752-4571. ; 14, s. 476-497
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Tidskriftsartikel (refereegranskat)abstract
- Various strains of the mycoparasitic fungal speciesClonostachys roseaare used commercially as biological control agents for the control of fungal plant diseases in agricultural crop production. Further improvements of the use and efficacy ofC. roseain biocontrol require a mechanistic understanding of the factors that determines the outcome of the interaction betweenC. roseaand plant pathogenic fungi. Here, we determined the genome sequences of 11Clonostachysstrains, representing five species inClonostachyssubgenusBionectria, and performed a comparative genomic analysis with the aim to identify gene families evolving under selection for gene gains or losses. Several gene families predicted to encode proteins involved in biosynthesis of secondary metabolites, including polyketide synthases, nonribosomal peptide syntethases and cytochrome P450s, evolved under selection for gene gains (p <= .05) in theBionectriasubgenus lineage. This was accompanied with gene copy number increases (p <= .05) in ATP-binding cassette (ABC) transporters and major facilitator superfamily (MFS) transporters predicted to contribute to drug efflux. MostClonostachysspecies were also characterized by high numbers of auxiliary activity (AA) family 9 lytic polysaccharide monooxygenases, AA3 glucose-methanol-choline oxidoreductases and additional carbohydrate-active enzyme gene families with putative activity (or binding) towards xylan and rhamnose/pectin substrates. Particular features of theC. roseagenome included expansions (p <= .05) of the ABC-B4 multidrug resistance transporters, the ABC-C5 multidrug resistance-related transporters and the 2.A.1.3 drug:H + antiporter-2 MFS drug resistance transporters. The ABC-G1 pleiotropic drug resistance transporter geneabcG6inC. roseawas induced (p <= .009) by exposure to the antifungalFusariummycotoxin zearalenone (1121-fold) and various fungicides. Deletion ofabcG6resulted in mutants with reduced (p < .001) growth rates on media containing the fungicides boscalid, fenhexamid and iprodione. Our results emphasize the role of biosynthesis of, and protection against, secondary metabolites inClonostachyssubgenusBionectria.
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- Fhager, Andreas, 1976, et al.
(författare)
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Microwave Technology in Medical Diagnostics and Treatment
- 2015
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Ingår i: 2015 Ieee Mtt-S International Microwave Workshop Series on Rf and Wireless Technologies for Biomedical and Healthcare Applications. - New York : Ieee. - 9781479985432 ; , s. 133-134
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- There is a great need for novel diagnostics and treatment tools in today's healthcare. In this paper we describe our development and progress in novel microwave based diagnostics and treatment applications. The target applications are stroke diagnostics, breast cancer detection and microwave hyperthermia.
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| 19. |
- Forsberg, Pontus, et al.
(författare)
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Diamond grating waveplates
- 2016
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Ingår i: Optical Materials Express. - : Optical Society of America. - 2159-3930. ; 6:6, s. 2024-2030
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Tidskriftsartikel (refereegranskat)abstract
- Two designs of diamond quarter-wave plates for CO2 lasers, based on the birefringence of sub-wavelength gratings, were manufactured and tested. In one design the grating was etched on the surface of a 300 mu m thick polycrystalline diamond substrate. The other consisted of a diamond grating hanging freely in air, suspended at the edges from a silicon frame. The free-hanging design, while more fragile, had several advantages both in terms of fabrication and performance such as a larger grating period, higher transmission, and no need for an antireflective treatment of the backside.
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| 24. |
- Gilljam, Mikael, 1957, et al.
(författare)
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Representatives' Attitudes Toward Citizen Protests in Sweden: The Impact of Ideology, Parliamentary Position and Experiences
- 2012
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Ingår i: Legislative Studies Quarterly. - : Wiley. - 0362-9805. ; 37:2, s. 251-268
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Tidskriftsartikel (refereegranskat)abstract
- What affects political representatives' attitudes toward citizen protests? We test the impact of political representatives' left-right ideology, parliamentary position, and earlier experience of citizen protests. Using data from a pioneering survey covering all local political representatives in Sweden (n = 9,101, response rate 70%), we examine attitudes toward controversial noninstitutionalized forms of citizen protests. The results show that representatives to the right show considerably lower protest acceptance than those to the left. Representatives in office show significantly lower levels of acceptance than those of the opposition. Finally, the results show that representatives with more protest experience show higher protest acceptance.
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| 25. |
- Guzzi, Nicola, et al.
(författare)
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Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
- 2018
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Ingår i: Cell. - : Elsevier BV. - 0092-8674 .- 1097-4172. ; 173:5, s. 26-1216
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Tidskriftsartikel (refereegranskat)abstract
- Pseudouridylation (Ψ) is the most abundant and widespread type of RNA epigenetic modification in living organisms; however, the biological role of Ψ remains poorly understood. Here, we show that a Ψ-driven posttranscriptional program steers translation control to impact stem cell commitment during early embryogenesis. Mechanistically, the Ψ “writer” PUS7 modifies and activates a novel network of tRNA-derived small fragments (tRFs) targeting the translation initiation complex. PUS7 inactivation in embryonic stem cells impairs tRF-mediated translation regulation, leading to increased protein biosynthesis and defective germ layer specification. Remarkably, dysregulation of this posttranscriptional regulatory circuitry impairs hematopoietic stem cell commitment and is common to aggressive subtypes of human myelodysplastic syndromes. Our findings unveil a critical function of Ψ in directing translation control in stem cells with important implications for development and disease. Translational control in stem cells is orchestrated by pseudouridylation of specific tRNA-derived fragments, impacting stem cell commitment during key developmental processes.
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