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- KARLSSON, E, et al.
(författare)
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QUANTUM DIFFUSION AND LOCALIZATION OF POSITIVE MUONS IN SUPERCONDUCTING ALUMINUM
- 1995
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Ingår i: PHYSICAL REVIEW B-CONDENSED MATTER. - : AMER INST PHYSICS. - 0163-1829. ; 52:9, s. 6417-6423
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Large differences were observed, indicating that the diffusion mechanism depends sensitively on the interaction between the muon and the conduction electrons. The samples were high-purity aluminum doped with controlled amounts of lithium. The lithium impu
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- Lidstrom, D, et al.
(författare)
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Agent based match racing simulations : Starting practice
- 2022
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Ingår i: SNAME 24th Chesapeake Sailing Yacht Symposium, CSYS 2022. - : Society of Naval Architects and Marine Engineers.
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Konferensbidrag (refereegranskat)abstract
- Match racing starts in sailing are strategically complex and of great importance for the outcome of a race. With the return of the America's Cup to upwind starts and the World Match Racing Tour attracting young and development sailors, the tactical skills necessary to master the starts could be trained and learned by means of computer simulations to assess a large range of approaches to the starting box. This project used game theory to model the start of a match race, intending to develop and study strategies using Monte-Carlo tree search to estimate the utility of a player's potential moves throughout a race. Strategies that utilised the utility estimated in different ways were defined and tested against each other through means of simulation and with an expert advice on match racing start strategy from a sailor's perspective. The results show that the strategies that put greater emphasis on what the opponent might do, perform better than those that did not. It is concluded that Monte-Carlo tree search can provide a basis for decision making in match races and that it has potential for further use.
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- Mereaux, JL, et al.
(författare)
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Increasing involvement of CAPN1 variants in spastic ataxias and phenotype-genotype correlations
- 2021
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Ingår i: Neurogenetics. - : Springer Science and Business Media LLC. - 1364-6753 .- 1364-6745. ; 22:1, s. 71-79
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Tidskriftsartikel (refereegranskat)abstract
- Spastic ataxias are rare neurogenetic disorders involving spinocerebellar and pyramidal tracts. Many genes are involved. Among them, CAPN1, when mutated, is responsible for a complex inherited form of spastic paraplegia (SPG76). We report the largest published series of 21 novel patients with nine new CAPN1 disease-causing variants and their clinical characteristics from two European university hospitals (Paris and Stockholm). After a formal clinical examination, causative variants were identified by next-generation sequencing and confirmed by Sanger sequencing. CAPN1 variants are a rare cause (~ 1.4%) of young-adult-onset spastic ataxia; however, together with all published cases, they allowed us to better describe the clinical and genetic spectra of this form. Truncating variants are the most frequent, and missense variants lead to earlier age at onset in favor of an additional deleterious effect. Cerebellar ataxia with cerebellar atrophy, dysarthria and lower limb weakness are often associated with spasticity. We also suggest that cognitive impairment and depression should be assessed specifically in the follow-up of SPG76 cases.
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