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1.	Karppinen, J, et al. (author) Serum biomarkers for Modic changes in patients with chronic low back pain 2021 In: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. - : Springer Science and Business Media LLC. - 1432-0932. ; 30:64, s. 1018-1027 Journal article (peer-reviewed)
2.	Koivisto, K, et al. (author) The Effect of Zoledronic Acid on Serum Biomarkers among Patients with Chronic Low Back Pain and Modic Changes in Lumbar Magnetic Resonance Imaging 2019 In: Diagnostics (Basel, Switzerland). - : MDPI AG. - 2075-4418. ; 9:4 Journal article (peer-reviewed)abstract The aim of the current study was to compare changes in serum biomarkers, including inflammatory mediators, signaling molecules, growth factors and markers of bone turnover after a single intravenous infusion of 5 mg zoledronic acid (ZA, a long-acting bisphosphonate; n = 20) or placebo (n = 20) among patients with Modic changes (MC) and chronic low back pain in a randomized controlled design. The MCs were classified into M1, predominating M1, predominating M2, and M2. We measured the serum concentrations of 39 biomarkers at baseline, and one month and one year after treatment. After Benjamini–Hochberg (B–H) correction, we observed significant differences in three biomarkers over one year: Interferon-γ-inducible protein (IP-10) had risen in the ZA group (p = 0.005), whereas alkaline phosphatase (AFOS) and intact procollagen I N-terminal propeptide (iPINP) had significantly decreased in the ZA group, but had not changed in the placebo group (p < 0.001 for both). Change in iPINP correlated with change in the volume of all MC and M1 lesions. ZA downregulated bone turnover markers as expected and, surprisingly, increased the chemokine IP-10 relative to placebo treatment. This adds to our knowledge of the effects of ZA on MC and the biomarkers that signal this process.
3.	Lehtimaki, S, et al. (author) Absence of CCR4 exacerbates skin inflammation in an oxazolone-induced contact hypersensitivity model 2010 In: The Journal of investigative dermatology. - : Elsevier BV. - 1523-1747 .- 0022-202X. ; 130:12, s. 2743-2751 Journal article (peer-reviewed)
4.	Leppilahti, J, et al. (author) Associations Between Glutathione-S-Transferase Genotypes and Bronchial Hyperreactivity Patients With Di-isocyanate Induced Asthma. A Follow-Up Study 2019 In: Frontiers in medicine. - : Frontiers Media SA. - 2296-858X. ; 6, s. 220- Journal article (peer-reviewed)
5.	Pulkkinen, V, et al. (author) Neuropeptide S and G protein-coupled receptor 154 modulate macrophage immune responses 2006 In: Human molecular genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 15:10, s. 1667-1679 Journal article (peer-reviewed)
6.	Sonkoly, E, et al. (author) MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4 2010 In: JOURNAL OF INVESTIGATIVE DERMATOLOGY. - 0022-202X. ; 130, s. S3-S3 Conference paper (other academic/artistic)

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Result 1-6 of 6

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Type of publication: journal article (5); conference paper (1)

Type of content: peer-reviewed (5); other academic/artistic (1)

Author/Editor: Majuri, ML (6); Alenius, H (5); Fyhrquist, N (2); Savinko, T (2); Wolff, H (2); Lauerma, A (2); show more...; Risteli, J (2); Koivisto, K (2); Haapea, M. (2); Karppinen, J. (2); Alini, M. (2); Niinimaki, J (2); Lotz, J (2); Dudli, S (2); Samartzis, D (2); Kyllonen, E (2); Jarvinen, J (2); Grad, S (2); Xu, N. (1); Nyman, T. (1); Kere, J (1); Stahle, M (1); Bradley, M (1); Vendelin, J (1); Pulkkinen, V (1); Sorsa, T (1); Homey, B (1); Lehtimaki, S (1); Winqvist, O (1); Sonkoly, E (1); Herzig, KH (1); Piirila, P. (1); Haahtela, T (1); Laitinen, T (1); Eidsmo, L (1); Hirvonen, A (1); Pivarcsi, A (1); Rehn, M (1); Janson, P (1); Matikainen, S (1); Puustinen, A (1); Ketola, J (1); Paananen, M (1); Tervonen, O (1); Laitinen, LA (1); Leppilahti, J (1); Tillander, S (1); Meisgen, F (1); Wei, TL (1); Obase, Y (1); show less...

University: Karolinska Institutet (6)

Language: English (6)

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