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Numrering	Referens	Omslagsbild	Hitta
1.	Bhangu, A, et al. (författare) Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study 2018 Ingår i: The Lancet. Infectious diseases. - : Elsevier. - 1474-4457 .- 1473-3099. ; 18:5, s. 516-525 Tidskriftsartikel (refereegranskat)
2.	Kielt, Matthew, et al. (författare) Classifying multicenter approaches to invasive mechanical ventilation for infants with bronchopulmonary dysplasia using hierarchical clustering analysis 2023 Ingår i: Pediatric Pulmonology. - : John Wiley & Sons. - 8755-6863 .- 1099-0496. ; 58:8, s. 2323-2332 Tidskriftsartikel (refereegranskat)abstract IntroductionEvidence-based ventilation strategies for infants with severe bronchopulmonary dysplasia (BPD) remain unknown. Determining whether contemporary ventilation approaches cluster as specific BPD strategies may better characterize care and enhance the design of clinical trials. The objective of this study was to test the hypothesis that unsupervised, multifactorial clustering analysis of point prevalence ventilator setting data would classify a discrete number of physiology-based approaches to mechanical ventilation in a multicenter cohort of infants with severe BPD.MethodsWe performed a secondary analysis of a multicenter point prevalence study of infants with severe BPD treated with invasive mechanical ventilation. We clustered the cohort by mean airway pressure (MAP), positive end expiratory pressure (PEEP), set respiratory rate, and inspiratory time (Ti) using Ward's hierarchical clustering analysis (HCA).ResultsSeventy-eight patients with severe BPD were included from 14 centers. HCA classified three discrete clusters as determined by an agglomerative coefficient of 0.97. Cluster stability was relatively strong as determined by Jaccard coefficient means of 0.79, 0.85, and 0.77 for clusters 1, 2, and 3, respectively. The median PEEP, MAP, rate, Ti, and PIP differed significantly between clusters for each comparison by Kruskall–Wallis testing (p < 0.0001).ConclusionsIn this study, unsupervised clustering analysis of ventilator setting data identified three discrete approaches to mechanical ventilation in a multicenter cohort of infants with severe BPD. Prospective trials are needed to determine whether these approaches to mechanical ventilation are associated with specific severe BPD clinical phenotypes and differentially modify respiratory outcomes.
3.	McKinney, Robin L, et al. (författare) Ventilatory Strategies in Infants With Established Severe Bronchopulmonary Dysplasia : A Multicenter Point Prevalence Study. 2022 Ingår i: The Journal of Pediatrics. - : Elsevier. - 0022-3476 .- 1097-6833. ; 242, s. 248-252.e1 Tidskriftsartikel (refereegranskat)abstract We performed a point prevalence study on infants with severe BPD collecting data on type and settings of ventilatory support; 187 infants were included from 15 centers, 51% who were on invasive positive pressure ventilation. We found significant center-specific variation in ventilator modes.
4.	Thomas, HS, et al. (författare) 2019 swepub:Mat__t

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Resultat 1-4 av 4

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Typ av publikation: tidskriftsartikel (3)

Typ av innehåll: refereegranskat (3)

Författare/redaktör: O'Neill, S (3); Cole, S. (2); Haddad, N. (2); Mahmoud, S. (2); Palma, A. (2); White, R. (2); visa fler...; Ye, J. (2); Ahmed, H. (2); Gupta, A. (2); Lim, H. (2); Aziz, NA (2); Kumar, S (2); Park, J (2); Wilson, M (2); Moore, R. (2); Zielinski, M. (2); Evans, D. (2); Roy, C. (2); Davies, R (2); Mohamed, A. (2); Mostafa, M. (2); Lopez, M. (2); Mohan, M. (2); Patel, P. (2); Hall, E (2); Ali, S (2); Mohammed, H (2); Mohammed, S (2); Negoi, I (2); Rickard, J (2); Abbas, A. (2); Kumar, B (2); Carpio, J. (2); Sharma, A (2); Mohamed, M. (2); Muller, J. (2); Sanchez, D. (2); Mustafa, M (2); Abdelhady, S (2); Abdelkader, M. (2); Yang, J. (2); Cox, M (2); Sander, A. (2); Roy, S (2); King, S. (2); Ali, A. (2); Sacco, M (2); Walker, M (2); Khan, R. (2); Sallinen, V (2); visa färre...

Lärosäte: Uppsala universitet (2); Umeå universitet (1); Karolinska Institutet (1)

Språk: Engelska (4)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (3)

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