↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Qu LX) "

Search: WFRF:(Qu LX)

Result 1-6 of 6

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Ahmad, T, et al. (author) Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries 2016 In: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 117:5, s. 601- Journal article (peer-reviewed)
2.	Ahmad, T, et al. (author) In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study 2017 In: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. - : Elsevier BV. - 1532-2157 .- 0748-7983. ; 43:12, s. 2324-2332 Journal article (peer-reviewed)
3.	Ahmad, T, et al. (author) Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery 2017 In: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 119:2, s. 258-266 Journal article (peer-reviewed)
4.	Wang, Y, et al. (author) Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer 2022 In: Cell death and differentiation. - : Springer Science and Business Media LLC. - 1476-5403 .- 1350-9047. ; 29:11, s. 2190-2202 Journal article (peer-reviewed)abstract The development of chemotherapy resistance is the most vital obstacle to clinical efficacy in gastric cancer (GC). The dysregulation of the Wnt/beta-catenin signaling pathway is critically associated with GC development and chemotherapy resistance. Ferroptosis is a form of regulated cell death, induced by an iron-dependent accumulation of lipid peroxides during chemotherapy. However, whether the Wnt/beta-catenin signaling directly controls resistance to cell death, remains unclear. Here, we show that the activation of the Wnt/beta-catenin signaling attenuates cellular lipid ROS production and subsequently inhibits ferroptosis in GC cells. The beta-catenin/TCF4 transcription complex directly binds to the promoter region of GPX4 and induces its expression, resulting in the suppression of ferroptotic cell death. Concordantly, TCF4 deficiency promotes cisplatin-induced ferroptosis in vitro and in vivo. Thus, we demonstrate that the aberrant activation of the Wnt/beta-catenin signaling confers ferroptosis resistance and suggests a potential therapeutic strategy to enhance chemo-sensitivity for advanced GC patients.
5.	Li, HG, et al. (author) Single-cell Transcriptomic Architecture Unraveling the Complexity of Tumor Heterogeneity in Distal Cholangiocarcinoma 2022 In: Cellular and molecular gastroenterology and hepatology. - : Elsevier BV. - 2352-345X. ; 13:5, s. 1592-1609.e9 Journal article (peer-reviewed)
6.	Li, Y, et al. (author) Effects on preventing mother-to-child transmission of syphilis and associated adverse pregnant outcomes: a longitudinal study from 2001 to 2015 in Shanghai, China 2017 In: BMC infectious diseases. - : Springer Science and Business Media LLC. - 1471-2334. ; 17:1, s. 626- Journal article (peer-reviewed)

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-6 of 6

Refine your search

Type of publication: journal article (6)

Type of content: peer-reviewed (6)

Author/Editor: Bai, Y. (3); Brown, J. (3); Chen, C. (3); Chen, H. (3); Chen, S. (3); Francis, D. (3); show more...; Huang, Y. (3); Li, B. (3); Li, H. (3); Liu, B. (3); Liu, M. (3); Liu, Y. (3); March, L. (3); Pinder, A. (3); Sanchez, A. (3); Silva, J. (3); Walker, R. (3); Wang, F. (3); Wang, J. (3); Webb, S. (3); White, S. (3); Williams, S. (3); Wilson, A. (3); Xu, L. (3); Yang, Y. (3); Zhang, H. (3); Zhang, J. (3); Zhang, L. (3); Zhu, Y. (3); Brenner, L. (3); Simon, D. (3); Zhou, C. (3); Brown, G. (3); Ellis, K. (3); Rose, A. (3); Zhao, L. (3); Ahmad, A. (3); He, M. (3); Ryan, P. (3); Schmitz, M. (3); Zhao, T. (3); Gupta, A. (3); Joseph, J. (3); Kennedy, J. (3); Li, J. (3); Yuan, J. (3); Zhang, Q. (3); Ren, Y. (3); Martin, J. (3); Alexander, M. (3); show less...

University: Karolinska Institutet (6); Linköping University (1); Lund University (1)

Language: English (6)

Research subject (UKÄ/SCB): Medical and Health Sciences (3)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view