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Sökning: WFRF:(Svensson Lennart)

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1.
  • Brante, Thomas, et al. (författare)
  • Inledning
  • 2019
  • Ingår i: Det professionella landskapets framväxt. - 9789144122052 ; , s. 17-54
  • Bokkapitel (refereegranskat)
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2.
  • Svensson, Kerstin, et al. (författare)
  • Det svenska professionella landskapet
  • 2019
  • Ingår i: Ett professionellt landskap i förvandling. - 9789144122274 ; , s. 15-60
  • Bokkapitel (refereegranskat)
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3.
  • Johnsson, Eva, et al. (författare)
  • Den psykosociala integrationens fält.
  • 2019
  • Ingår i: Det professionella landskapets framväxt. - 9789144122052 ; , s. 261-331
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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4.
  • Svensson, Lennart, et al. (författare)
  • Psykosociala integrationens fält i nutid
  • 2019
  • Ingår i: Ett professionellt landskap i förvandling. - 9789144122274 ; , s. 217-271
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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5.
  • Lundh, Christer, et al. (författare)
  • Regional Wages in Sweden 1860-1914
  • 2004
  • Ingår i: Wage Formation, Labour Market Institutions and Economic Transformation in Sweden 1860-2000. ; 32
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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6.
  • Svensson, Kerstin, et al. (författare)
  • Den sociala regleringens fält
  • 2019
  • Ingår i: Det professionella landskapets framväxt. - 9789144122052 ; , s. 209-260
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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7.
  • Svensson, Kerstin, et al. (författare)
  • Den sociala regleringens professioner
  • 2019
  • Ingår i: Ett professionellt landskap i förvandling. - 9789144122274 ; , s. 171-216
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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8.
  • Almqvist, Erik, et al. (författare)
  • Increased plasma concentrations of N-terminal pro-B-type natriuretic peptide in patients with mild primary hyperparathyroidism.
  • 2006
  • Ingår i: Clinical endocrinology. - : Wiley. - 0300-0664 .- 1365-2265. ; 65:6, s. 760-6
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: Primary hyperparathyroidism (PHPT) is associated with heart disease. The aims of the present study were to evaluate how cardiac function and secretion of N-terminal pro-B-type natriuretic peptide (NT-proBNP) correlate in patients with mild PHPT, and how the plasma level of NT-proBNP is influenced by cure of the parathyroid disease. DESIGN AND PATIENTS: Forty-two patients with PHPT without symptoms of heart disease were examined before and 1 year after curative parathyroidectomy. MEASUREMENTS: Plasma or serum concentrations of NT-proBNP, calcium, PTH, creatinine, oestradiol, testosterone and SHBG were measured. Cardiac function was evaluated by equilibrium radionuclide angiography (ERNA). RESULTS: At baseline, NT-proBNP levels correlated negatively with systolic function [left ventricular ejection fraction (LVEF), P < 0.001]. Twelve per cent of the patients had NT-proBNP levels above normal reference values preoperatively. One year postoperatively, the corresponding proportion was 21%. The mean plasma concentration of NT-proBNP increased after parathyroidectomy (P < 0.01) in parallel with a dip in diastolic function (peak filling rate, P < 0.05) and a falling trend in systolic function (LVEF, P = 0.08). The postoperative percentage changes in circulating NT-proBNP and total oestradiol correlated positively (P < 0.05). CONCLUSIONS: Patients with mild PHPT and normal renal function may have high levels of circulating NT-proBNP despite the absence of symptomatic heart disease. Cure of the parathyroid disease is followed by a further increase in NT-proBNP secretion in parallel with ERNA measures, indicating subclinical changes in heart function. These results are in line with data indicating an association between PHPT and increased risk of premature death.
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11.
  • Andrén, Lennart, 1946, et al. (författare)
  • Ketanserin in hypertension. Early clinical evaluation and dose finding study of a new 5-HT2 receptor antagonist.
  • 1983
  • Ingår i: Acta medica Scandinavica. - 0001-6101. ; 214:2, s. 125-30
  • Tidskriftsartikel (refereegranskat)abstract
    • Ketanserin, a new 5-hydroxy-tryptamine antagonist, was given at three different dosage levels (double-blind, randomized) in a dose finding study for 2 months to 31 patients with mild to moderately severe essential hypertension. Treatment with ketanserin was then continued until 9 months had been completed. A significant antihypertensive effect was demonstrated at daily dosages of 20 mg t.i.d. or 40 mg t.i.d. The antihypertensive effect was similar to that of previous multiple drug treatment with conventional drugs. However, 60 mg t.i.d. was not acceptable, at least not as initial dosage. At this dose level, 8 out of 10 patients had to be withdrawn from the study during the initial phase due to unwanted effects. It is conceivable that alpha 1-adrenoceptor blockade may have played a role at this dose level, since postural reactions were observed which was otherwise not the case during this study. Ketanserin is a new and interesting alternative in the treatment of hypertension. At the same time it offers a tool by which the role of 5-hydroxy-tryptamine in the regulation of arterial pressure can be investigated.
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13.
  • Axelsson, Robert, et al. (författare)
  • Evaluation of Multi-level Social Learning for Sustainable Landscapes : Perspective of a Development Initiative in Bergslagen, Sweden
  • 2013
  • Ingår i: Ambio. - : Springer Netherlands. - 0044-7447 .- 1654-7209. ; 42:2, s. 241-253
  • Tidskriftsartikel (refereegranskat)abstract
    • To implement policies about sustainable landscapes and rural development necessitates social learning about states and trends of sustainability indicators, norms that define sustainability, and adaptive multi-level governance. We evaluate the extent to which social learning at multiple governance levels for sustainable landscapes occur in 18 local development initiatives in the network of Sustainable Bergslagen in Sweden. We mapped activities over time, and interviewed key actors in the network about social learning. While activities resulted in exchange of experiences and some local solutions, a major challenge was to secure systematic social learning and make new knowledge explicit at multiple levels. None of the development initiatives used a systematic approach to secure social learning, and sustainability assessments were not made systematically. We discuss how social learning can be improved, and how a learning network of development initiatives could be realized.
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14.
  • Bergström, Staffan, et al. (författare)
  • Development and application of an analytical protocol for evaluation of treatment processes for landfill leachates : I. Development of an analytical protocol for handling organic compounds in complex leachate samples
  • 2007
  • Ingår i: International Journal of Environmental Analytical Chemistry. - 0306-7319 .- 1029-0397. - 0306-7319 ; 87:1, s. 1-15
  • Tidskriftsartikel (refereegranskat)abstract
    • A strategy is presented for evaluation of treatment procedures for landfill leachate with emphasis on organic pollutants. An analytical scheme, the LAQUA protocol, was developed as a guide for the analytical work. The protocol includes organic as well as metals,. inorganic ions, water-quality parameters, and toxicity. The proposed strategy considers the behaviour of both polar and non-polar organic substances at trace levels. For polar substances, phenols were chosen as markers and determined with an automated supported liquid membrane extraction device, coupled on-line to HPLC with a diode-array detector. For non-polar substances, PCBs and 10 unidentified compounds were chosen as markers and analysed by solid-phase extraction combined with supercritical fluid extraction with GC analysis. The chosen measurement strategy, based on the use of marker substances, difference measurements, and versatile data-handling procedures, provided essential information about complex systems at relatively low cost.
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15.
  • Bergström, Staffan, et al. (författare)
  • Development and application of an analytical protocol for evaluation of treatment processes for landfill leachates. I. Development of an analytical protocol for handling organic compounds in complex leachate samples
  • 2007
  • Ingår i: International Journal of Environmental Analytical Chemistry. - : Informa UK Limited. - 1029-0397 .- 0306-7319. ; 87:1, s. 1-15
  • Tidskriftsartikel (refereegranskat)abstract
    • A strategy is presented for evaluation of treatment procedures for landfill leachate with emphasis on organic pollutants. An analytical scheme, the LAQUA protocol, was developed as a guide for the analytical work. The protocol includes organic as well as metals,. inorganic ions, water-quality parameters, and toxicity. The proposed strategy considers the behaviour of both polar and non-polar organic substances at trace levels. For polar substances, phenols were chosen as markers and determined with an automated supported liquid membrane extraction device, coupled on-line to HPLC with a diode-array detector. For non-polar substances, PCBs and 10 unidentified compounds were chosen as markers and analysed by solid-phase extraction combined with supercritical fluid extraction with GC analysis. The chosen measurement strategy, based on the use of marker substances, difference measurements, and versatile data-handling procedures, provided essential information about complex systems at relatively low cost.
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17.
  • Crouse, David F., et al. (författare)
  • The Set MHT
  • 2011
  • Ingår i: 14th International Conference on Information Fusion, Fusion 2011; Chicago, IL; 5 July 2011 through 8 July 2011. - 9781457702679
  • Konferensbidrag (refereegranskat)abstract
    • Abstract—We introduce the Set MHT, a tracking algorithmthat maintains multiple hypotheses and produces “smooth”estimates without the track coalescence often associated withMinimum Mean Squared Error (MMSE) estimation or thejitter associated with Maximum Likelihood (ML) estimation.It does this by utilizing Minimum Mean Optimal SubpatternAssignment (MMOSPA) estimation techniques coupled with atheoretically-grounded approach for probabilistically determiningthe identities of the state estimates. Unlike traditional MHTalgorithms, the Set MHT does not “forget” uncertainty in targetidentities, i.e. display an unjustifiably high confidence level inthe target identities, as a result of pruning out competinghypotheses. Rather, it uses merging techniques while avoiding theshortcomings of traditional Gaussian mixture reduction trackers.
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18.
  • Dahlöf, Björn, 1953, et al. (författare)
  • Addition of the calcium antagonist PN 200-110 to pindolol markedly augments the antihypertensive effect in essential hypertension.
  • 1987
  • Ingår i: Journal of cardiovascular pharmacology. - 0160-2446. ; 10 Suppl 10
  • Tidskriftsartikel (refereegranskat)abstract
    • Several large-scale studies have recently drawn attention to the fact that arterial hypertension frequently is inadequately controlled and that therapeutic alternatives other than the commonly employed stepped-care treatment may be needed in order to obtain normotension. For this reason PN 200-110, a new dihydropyridine calcium antagonist--at two different dose levels (average 3.8 mg b.i.d. or 5.7 mg b.i.d.)--or placebo was added in a double-blind cross-over trial to pindolol, 10 mg per day, in 20 patients with essential hypertension, after an initial 3-week placebo period. Ionized calcium in serum was determined repeatedly during the study. From an initial level of 157/100 mm Hg, PN 200-110 at the first dose level reduced blood pressure by 14/11 mm Hg (p less than 0.01/0.001) and at the second dose level reduced blood pressure by 22/18 mm Hg (p less than 0.001/0.001). The reduction in mean arterial pressure was significantly correlated to age (=0.050, p less than 0.05). There was no significant increase in heart rate, nor were there any significant correlations between ionized calcium and the effect of PN 200-110 nor between the changes in ionized calcium and the changes in blood pressure. Adverse effects were few and mild. One patient had to be withdrawn because of side effects, probably not related to the investigated drugs. Thus, addition of PN 200-110 to hypertensive patients treated with pindolol caused highly significant and clinically relevant further reductions in arterial pressure. The results show that a combination of this kind offers the possibility of good blood pressure control.
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19.
  • Dahlöf, Björn, 1953, et al. (författare)
  • Potentiation of the antihypertensive effect of enalapril by randomized addition of different doses of hydrochlorothiazide.
  • 1985
  • Ingår i: Journal of hypertension. Supplement : official journal of the International Society of Hypertension. - 0952-1178. ; 3:3
  • Tidskriftsartikel (refereegranskat)abstract
    • The purpose of this study was to evaluate the potentiating effect of hydrochlorothiazide (HCTZ) 12.5 or 25 mg once daily when added in a placebo-controlled double-blind randomized study of patients with essential hypertension, whose diastolic blood pressure (DBP) was not adequately controlled (DBP > 90 mmHg) following 6 weeks of single-blind treatment with the angiotensin converting enzyme (ACE) inhibitor enalapril, 20 mg once daily. Forty-eight patients started the first period with enalapril after 4 weeks on placebo. In 13 patients DBP fell to < or = 90 mmHg after enalapril for 6 weeks. In this group supine mean arterial pressure (MAP) was reduced by 13% (P < 0.01). In the patients whose DBP was > 90 mmHg after 6 weeks on enalapril (n = 32) the average supine MAP fell by 9% (P < 0.001). After 3 weeks there was no further drop in blood pressure (BP). Addition of HCTZ to the 32 patients with DBP > 90 mmHg caused a significant further drop in supine BP by 13/7 mmHg with 12.5 mg and by 15/7 mmHg with 25 mg. Seven patients discontinued the study, none due to side effects on enalapril alone. Well-being, assessed with a special questionnaire, was significantly better with enalapril as monotherapy compared with previous treatment, but not different from well-being during the placebo periods. It is concluded that 20 mg enalapril once daily lowered BP effectively and was well tolerated. The maximum BP lowering effect was seen within 3 weeks. Addition of HCTZ caused a significant, and clinically relevant, further drop in BP.(ABSTRACT TRUNCATED AT 250 WORDS)
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20.
  • Dahlöf, Björn, 1953, et al. (författare)
  • The long-term effect of isradipine in pindolol-treated patients.
  • 1987
  • Ingår i: Journal of hypertension. Supplement : official journal of the International Society of Hypertension. - 0952-1178. ; 5:5
  • Tidskriftsartikel (refereegranskat)abstract
    • The long-term efficacy of isradipine, a new dihydropyridine calcium antagonist with marked vascular selectivity, was evaluated in 17 patients with essential hypertension. All had a supine diastolic blood pressure of greater than 95 mmHg with 10 mg pindolol once daily. After a short-term, double-blind, dose-finding, crossover comparison with addition of isradipine or placebo twice daily, they continued on pindolol and their optimal dose of isradipine in a single-blind, long-term follow-up study. Eighteen patients were recruited but one male patient discontinued treatment after 2 weeks due to ankle oedema and will not be accounted for in the overall evaluation. There were 11 males and six females with a mean age of 56 +/- 10 years. In the short-term study on the optimal dose of isradipine (5.1 mg twice daily) blood pressure was lowered by 24/18 mmHg (P less than 0.001). No change in heart rate was seen despite the substantial drop in blood pressure. In the long-term study the patients were seen for a mean follow-up time of 12.5 months (range 4-17 months). After the longest follow-up time mean arterial pressure was 107.0 +/- 7.4 compared with 120.1 +/- 8.2 mmHg after placebo baseline [delta = 13 mmHg (11%), P less than 0.001, n = 17]. The heart rate was unchanged (delta = 0.2 beats/min, 95% confidence limits -3, +3), and so was ankle circumference (delta = 0.12 cm, 95% confidence interval, -1, +1). On the other hand, mean weight was reduced by 2 kg from 90 kg (P less than 0.05, n = 17).(ABSTRACT TRUNCATED AT 250 WORDS)
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23.
  • Funck, Elin, et al. (författare)
  • Det medicinska professionella fältet
  • 2019. - 1
  • Ingår i: Ett professionellt landskap i förvandling. - Lund : Studentlitteratur AB. - 9789144122274 ; , s. 271-306
  • Bokkapitel (refereegranskat)
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25.
  • Guerriero, Marco, et al. (författare)
  • Shooting two birds with two bullets: how to find Minimum Mean OSPA estimates
  • 2010
  • Ingår i: Proceedings of the 13th International Conference on Information Fusion.
  • Konferensbidrag (refereegranskat)abstract
    • Most area-defense formulations followfrom the assumption that threats must first be identifiedand then neutralized. This is reasonable, but inherentto it is a process of labeling: threat A must be identifiedand then threat B, and then action must be taken.This manuscript begins from the assumption that suchlabeling (A & B) is irrelevant. The problem naturallydevolves to one of Random Finite Set (RFS) estimation:we show that by eschewing any concern of targetlabel we relax the estimation procedure, and it is perhapsnot surprising that by such a removal of constraint (oflabeling) performance (in terms of localization) is enhanced.A suitable measure for the estimation of unlabeledobjects is the Mean OSPA (MOSPA). We derive ageneral algorithm which provided the optimal estimatorwhich minimize the MOSPA. We call such an estimatora Minimum MOSPA (MMOSPA) estimator.
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