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Sökning: WFRF:(Thöne C. C.)

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1.
  • Fynbo, J. P. U., et al. (författare)
  • Low-resolution Spectroscopy of Gamma-ray Burst Optical Afterglows : Biases in the Swift Sample and Characterization of the Absorbers
  • 2009
  • Ingår i: Astrophysical Journal Supplement Series. - : American Astronomical Society. - 0067-0049 .- 1538-4365. ; 185:2, s. 526-573
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a sample of 77 optical afterglows (OAs) of Swift detected gamma-ray bursts (GRBs) for which spectroscopic follow-up observations have been secured. Our first objective is to measure the redshifts of the bursts. For the majority (90%) of the afterglows, the redshifts have been determined from the spectra. We provide line lists and equivalent widths (EWs) for all detected lines redward of Lyα covered by the spectra. In addition to the GRB absorption systems, these lists include line strengths for a total of 33 intervening absorption systems. We discuss to what extent the current sample of Swift bursts with OA spectroscopy is a biased subsample of all Swift detected GRBs. For that purpose we define an X-ray-selected statistical sample of Swift bursts with optimal conditions for ground-based follow-up from the period 2005 March to 2008 September; 146 bursts fulfill our sample criteria. We derive the redshift distribution for the statistical (X-ray selected) sample and conclude that less than 18% of Swift bursts can be at z > 7. We compare the high-energy properties (e.g., γ-ray (15-350 keV) fluence and duration, X-ray flux, and excess absorption) for three subsamples of bursts in the statistical sample: (1) bursts with redshifts measured from OA spectroscopy; (2) bursts with detected optical and/or near-IR afterglow, but no afterglow-based redshift; and (3) bursts with no detection of the OA. The bursts in group (1) have slightly higher γ-ray fluences and higher X-ray fluxes and significantly less excess X-ray absorption than bursts in the other two groups. In addition, the fractions of dark bursts, defined as bursts with an optical to X-ray slope βOX < 0.5, is 14% in group (1), 38% in group (2), and >39% in group (3). For the full sample, the dark burst fraction is constrained to be in the range 25%-42%. From this we conclude that the sample of GRBs with OA spectroscopy is not representative for all Swift bursts, most likely due to a bias against the most dusty sight lines. This should be taken into account when determining, e.g., the redshift or metallicity distribution of GRBs and when using GRBs as a probe of star formation. Finally, we characterize GRB absorption systems as a class and compare them to QSO absorption systems, in particular the damped Lyα absorbers (DLAs). On average GRB absorbers are characterized by significantly stronger EWs for H I as well as for both low and high ionization metal lines than what is seen in intervening QSO absorbers. However, the distribution of line strengths is very broad and several GRB absorbers have lines with EWs well within the range spanned by QSO-DLAs. Based on the 33 z > 2 bursts in the sample, we place a 95% confidence upper limit of 7.5% on the mean escape fraction of ionizing photons from star-forming galaxies. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere, Chile, under programs 275.D-5022 (PI: Chincarini), 075.D-0270 (PI: Fynbo), 077.D-0661 (PI: Vreeswijk), 077.D-0805 (PI: Tagliaferri), 177.A-0591 (PI: Hjorth), 078.D-0416 (PI: Vreeswijk), 079.D-0429 (PI: Vreeswijk), 080.D-0526 (PI: Vreeswijk), 081.A-0135 (PI: Greiner), 281.D-5002 (PI: Della Valle), and 081.A-0856 (PI: Vreeswijk). Also based on observations made with the Nordic Optical Telescope, operated on the island of La Palma jointly by Denmark, Finland, Iceland, Norway, and Sweden, in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias. Some of the data obtained herein were obtained at the W.M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W.M. Keck foundation.
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2.
  • Lyman, J. D., et al. (författare)
  • The optical afterglow of the short gamma-ray burst associated with GW170817
  • 2018
  • Ingår i: Nature Astronomy. - : Springer Science and Business Media LLC. - 2397-3366. ; 2:9, s. 751-754
  • Tidskriftsartikel (refereegranskat)abstract
    • The binary neutron star merger GW170817 was the first multi-messenger event observed in both gravitational and electromagnetic waves(1,2). The electromagnetic signal began approximately two seconds post-merger with a weak, short burst of gamma rays(3), which was followed over the next hours and days by the ultraviolet, optical and near-infrared emission from a radioactively powered kilonova(4-11). Later, non-thermal rising X-ray and radio emission was observed(12,13). The low luminosity of the gamma rays and the rising non-thermal flux from the source at late times could indicate that we are outside the opening angle of the beamed relativistic jet. Alternatively, the emission could be arising from a cocoon of material formed from the interaction between a jet and the merger ejecta(13-15). Here we present late-time optical detections and deep near-infrared limits on the emission from GW170817 at 110 days post-merger. Our new observations are at odds with expectations of late-time emission from kilonova models, being too bright and blue(16,17). Instead, the emission arises from the interaction between the relativistic ejecta of GW170817 and the interstellar medium. We show that this emission matches the expectations of a Gaussian-structured relativistic jet, which would have launched a high-luminosity, short gamma-ray burst to an aligned observer. However, other jet structure or cocoon models can also match current data-the future evolution of the afterglow will directly distinguish the origin of the emission.
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3.
  • Schady, P., et al. (författare)
  • Comparing emission- and absorption-based gas-phase metallicities in GRB host galaxies at z =2-4 using JWST
  • 2024
  • Ingår i: Monthly notices of the Royal Astronomical Society. - 0035-8711 .- 1365-2966. ; 529:3, s. 2807-2831
  • Tidskriftsartikel (refereegranskat)abstract
    • Much of what is known of the chemical composition of the universe is based on emission line spectra from star-forming galaxies. Emission-based inferences are, nevertheless, model-dependent and they are dominated by light from luminous star-forming regions. An alternative and sensitive probe of the metallicity of galaxies is through absorption lines imprinted on the luminous afterglow spectra of long gamma ray bursts (GRBs) from neutral material within their host galaxy. We present results from a JWST/NIRSpec programme to investigate for the first time the relation between the metallicity of neutral gas probed in absorption by GRB afterglows and the metallicity of the star-forming regions for the same host galaxy sample. Using an initial sample of eight GRB host galaxies at z = 2.1–4.7, we find a tight relation between absorption and emission line metallicities when using the recently proposed ?^ metallicity diagnostic (±0.2 dex). This agreement implies a relatively chemically homogeneous multiphase interstellar medium and indicates that absorption and emission line probes can be directly compared. However, the relation is less clear when using other diagnostics, such as R23 and R3. We also find possible evidence of an elevated N/O ratio in the host galaxy of GRB 090323 at z = 4.7, consistent with what has been seen in other z > 4 galaxies. Ultimate confirmation of an enhanced N/O ratio and of the relation between absorption and emission line metallicities will require a more direct determination of the emission line metallicity via the detection of temperature-sensitive auroral lines in our GRB host galaxy sample.
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4.
  • Singer, L. P., et al. (författare)
  • The Needle in the 100 deg2 Haystack : Uncovering Afterglows of Fermi GRBs with the Palomar Transient Factory
  • 2015
  • Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 806:1
  • Tidskriftsartikel (refereegranskat)abstract
    • The Fermi Gamma-Ray Space Telescope has greatly expanded the number and energy window of observations of gamma-ray bursts (GRBs). However, the coarse localizations of tens to a hundred square degrees provided by the Fermi Gamma-ray Burst Monitor (GBM) instrument have posed a formidable obstacle to locating the bursts' host galaxies, measuring their redshifts, and tracking their panchromatic afterglows. We have built a target of opportunity mode for the intermediate Palomar Transient Factory (iPTF) in order to perform targeted searches for Fermi afterglows. Here, we present the results of one year of this program: eight afterglow discoveries, two of which (GRBs 130702A and 140606B) were at low redshift (z=0.145 and 0.384 respectively) and had spectroscopically confirmed broad-line type Ic supernovae. We present our broadband follow-up including spectroscopy as well as X-ray, UV, optical, millimeter, and radio observations. We study possible selection effects in the context of the total Fermi and Swift GRB samples. We identify one new outlier on the Amati relation. We find that two bursts are consistent with a mildly relativistic shock breaking out from the progenitor star, rather than the ultra-relativistic internal shock mechanism that powers standard cosmological bursts. Finally, in the context of the Zwicky Transient Facility (ZTF), we discuss how we will continue to expand this effort to find optical counterparts of binary neutron star mergers that may soon be detected by Advanced LIGO and Virgo.
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5.
  • Cano, Z., et al. (författare)
  • GRB 161219B/SN 2016jca : A low-redshift gamma-ray burst supernova powered by radioactive heating
  • 2017
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 605
  • Tidskriftsartikel (refereegranskat)abstract
    • Since the first discovery of a broad-lined type Ic supernova (SN) with a long-duration gamma-ray burst (GRB) in 1998, fewer than fifty GRB-supernovae (SNe) have been discovered. The intermediate-luminosity Swift GRB 161219B and its associated supernova SN 2016jca, which occurred at a redshift of z = 0.1475, represents only the seventh GRB-SN to have been discovered within 1 Gpc, and hence provides an excellent opportunity to investigate the observational and physical properties of these very elusive and rare type of SN. As such, we present optical to near-infrared photometry and optical spectroscopy of GRB 161219B and SN 2016jca, spanning the first three months since its discovery. GRB 161219B exploded in the disk of an edge-on spiral galaxy at a projected distance of 3.4 kpc from the galactic centre. GRB 161219B itself is an outlier in the E-p,E-i - E-gamma,E-iso plane, while SN 2016jca had a rest-frame, peak absolute V-band magnitude of M-V = -19.0 +/- 0.1, which it reached after 12.3 +/- 0.7 rest-frame days. We find that the bolometric properties of SN 2016jca are inconsistent with being powered solely by a magnetar central engine, and demonstrate that it was likely powered exclusively by energy deposited by the radioactive decay of nickel and cobalt into their daughter products, which were nucleosynthesised when its progenitor underwent core collapse. We find that 0.22 +/- 0.08 M-circle dot of nickel is required to reproduce the peak luminosity of SN 2016jca, and we constrain an ejecta mass of 5.8 +/- 0.3 M-circle dot and a kinetic energy of 5.1 +/- 0.8 x 10(52) erg. Finally, we report on a chromatic, pre-maximum bump in the g-band light curve, and discuss its possible origin.
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6.
  • Lamb, G. P., et al. (författare)
  • Short GRB 160821B : A Reverse Shock, a Refreshed Shock, and a Well-sampled Kilonova
  • 2019
  • Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 883:1
  • Tidskriftsartikel (refereegranskat)abstract
    • We report our identification of the optical afterglow and host galaxy of the short-duration gamma-ray burst sGRB 160821B. The spectroscopic redshift of the host is z = 0.162, making it one of the lowest redshift short-duration gamma-ray bursts (sGRBs) identified by Swift. Our intensive follow-up campaign using a range of ground-based facilities as well as Hubble Space Telescope, XMM-Newton, and Swift, shows evidence for a late-time excess of optical and near-infrared emission in addition to a complex afterglow. The afterglow light curve at X-ray frequencies reveals a narrow jet, theta(j) similar to 1.9(-0.03)(+0.10) deg, that is refreshed at >1 day post-burst by a slower outflow with significantly more energy than the initial outflow that produced the main GRB. Observations of the 5 GHz radio afterglow shows a reverse shock into a mildly magnetized shell. The optical and near-infrared excess is fainter than AT2017gfo associated with GW170817, and is well explained by a kilonova with dynamic ejecta mass M-dyn = (1.0 +/- 0.6) x 10(-3) M-circle dot and a secular (post-merger) ejecta mass with M-pm = (1.0 +/- 0.6) x 10(-2) M-circle dot, consistent with a binary neutron star merger resulting in a short-lived massive neutron star. This optical and near-infrared data set provides the best-sampled kilonova light curve without a gravitational wave trigger to date.
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7.
  • Sollerman, J., et al. (författare)
  • Supernova 2006aj and the associated X-Ray Flash 060218
  • 2006
  • Ingår i: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 454, s. 503-509
  • Tidskriftsartikel (refereegranskat)abstract
    • We have studied the afterglow of the gamma-ray burst (GRB) of February 18, 2006. This is a nearby long GRB, with a very low peak energy, and is therefore classified as an X-ray Flash (XRF). XRF 060218 is clearly associated with a supernova - dubbed SN 2006aj. We present early spectra for SN 2006aj as well as optical lightcurves reaching out to 50 days past explosion. Our optical lightcurves define the rise times, the lightcurve shapes and the absolute magnitudes in the U, V and R bands, and we compare these data with data for other relevant supernovae. SN 2006aj evolved quite fast, somewhat similarly to SN 2002ap, but not as fast as SN 1994I. Our spectra show the evolution of the supernova over the peak, when the U-band portion of the spectrum rapidly fades due to extensive line blanketing. We compare to similar spectra of very energetic type Ic supernovae. Our first spectra are earlier than spectra for any other GRB-SN. The spectrum taken 12 days after burst in the rest frame is similar to somewhat later spectra of both SN 1998bw and SN 2003dh, implying a rapid early evolution. This is consistent with the fast lightcurve. From the narrow emission lines from the host galaxy we derive a redshift of z=0.0331±0.0007. This makes XRF 060218 the second closest gamma-ray burst detected. The flux of these emission lines indicate a high-excitation state, and a modest metallicity and star formation rate of the host galaxy.
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8.
  • Vergani, S. D., et al. (författare)
  • GRB 091127/SN 2009nz and the VLT/X-shooter spectroscopy of its host galaxy : probing the faint end of the mass-metallicity relation
  • 2011
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 535, s. A127-
  • Tidskriftsartikel (refereegranskat)abstract
    • We perform a detailed study of the gamma-ray burst GRB 091127/SN 2009nz host galaxy at z = 0.490 using the VLT/X-shooter spectrograph in slit and integral-field unit (IFU) mode. From the analysis of the optical and X-ray afterglow data obtained from ground-based telescopes and Swift-XRT, we confirm the presence of a bump associated with SN 2009nz and find evidence of a possible jet break in the afterglow lightcurve. The X-shooter afterglow spectra reveal several emission lines from the underlying host, from which we derive its integrated properties. These properties agree with those of previously studied GRB-SN hosts and, more generally, with those of the long GRB host population. We use the Hubble Space Telescope and ground-based images of the host to determine its stellar mass (M⋆). Our results extend to lower M⋆ values the M-Z plot derived for the sample of long GRB hosts at 0.3 < z < 1.0 adding new information to probe the faint end of the M-Z relation and the shift of the LGRB host M-Z relation from that found from emission-line galaxy surveys. Thanks to the IFU spectroscopy, we can build the two-dimensional (2D) velocity, velocity dispersion, and star formation rate (SFR) maps. They show that the host galaxy has perturbed rotation kinematics with evidence of a SFR enhancement consistent with the afterglow position. Based on observations made with ESO Telescopes at Paranal Observatory under programmes ID 084.A-0260 and 086.A-0874.
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9.
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10.
  • D'Elia, V., et al. (författare)
  • VLT/X-shooter spectroscopy of the GRB 090926A afterglow
  • 2010
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 523, s. 36-
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims: The aim of this paper is to study the environment and intervening absorbers of the gamma-ray burst GRB 090926A through analyzing optical spectra of its afterglow. Methods: We analyzed medium-resolution spectroscopic observations (R = 10 000, corresponding to 30 km s-1, S/N = 15-30 and wavelength range 3000-25 000) of the optical afterglow of GRB 090926A, taken with X-shooter at the VLT ~22 h after the GRB trigger. Results: The spectrum shows that the ISM in the GRB host galaxy at z = 2.1071 is rich in absorption features, with two components contributing to the line profiles. In addition to the ground state lines, we detect C ii, O i, Si ii, Fe ii, and Ni ii-excited absorption features, which we used to derive information on the distance between the host absorbing gas and the site of the GRB explosion. The distance of component I is found to be 2.40 ± 0.15 kpc, while component II is located far away from the GRB, possibly at ~5 kpc. These values are compatible with those found for other GRBs. The hydrogen column density associated to GRB 090926A is log NH/cm -2 = 21.60 ± 0.07, and the metallicity of the host galaxy is in the range [X/H] = -2.5 to -1.9 with respect to the solar values, i.e., among the lowest values ever observed for a GRB host galaxy. A comparison with galactic chemical evolution models has suggested that the host of GRB090926A is likely to be a dwarf-irregular galaxy. No emission lines were detected, but a Hα flux in emission of 9 × 10-18 erg s-1 cm-2 (i.e., a star-formation rate of 2 M_ȯ yr-1), which is typical of many GRB hosts, would have been detected in our spectra, and thus emission lines are well within the reach of X-shooter. We put an upper limit to the H molecular fraction of the host galaxy ISM, which is f < 7 × 10-7. The continuum has been fitted assuming a power-law spectrum, with a spectral index of β = 0.89-0.02+0.02. The best fit does essentially not require any intrinsic extinction because EB-V < 0.01 mag adopting a SMC extinction curve. Finally, the line of sight of GRB 090926A presents four weak intervening absorption systems in the redshift range 1.24 < z < 1.95. Based on observations collected at the European Southern Observatory, ESO, the VLT/Kueyen telescope, Paranal, Chile, during the science verification phase, proposal code: 060-9427(A).
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11.
  • Levan, A. J., et al. (författare)
  • The Environment of the Binary Neutron Star Merger GW170817
  • 2017
  • Ingår i: Astrophysical Journal Letters. - : American Astronomical Society. - 2041-8205 .- 2041-8213. ; 848:2
  • Tidskriftsartikel (refereegranskat)abstract
    • We present Hubble Space Telescope (HST) and Chandra imaging, combined with Very Large Telescope MUSE integral field spectroscopy of the counterpart and host galaxy of the first binary neutron star merger detected via gravitational-wave emission by LIGO and Virgo, GW170817. The host galaxy, NGC 4993, is an S0 galaxy at z - 0.009783. There is evidence for large, face-on spiral shells in continuum imaging, and edge-on spiral features visible in nebular emission lines. This suggests that NGC 4993 has undergone a relatively recent (less than or similar to 1 Gyr) dry merger. This merger may provide the fuel for a weak active nucleus seen in Chandra imaging. At the location of the counterpart, HST imaging implies there is no globular or young stellar cluster, with a limit of a few thousand solar masses for any young system. The population in the vicinity is predominantly old with less than or similar to 1% of any light arising from a population with ages <500 Myr. Both the host galaxy properties and those of the transient location are consistent with the distributions seen for short-duration gamma-ray bursts, although the source position lies well within the effective radius (r(e) similar to 3 kpc), providing an r(e)-normalized offset that is closer than similar to 90% of short GRBs. For the long delay time implied by the stellar population, this suggests that the kick velocity was significantly less than the galaxy escape velocity. We do not see any narrow host galaxy interstellar medium features within the counterpart spectrum, implying low extinction, and that the binary may lie in front of the bulk of the host galaxy.
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12.
  • Melandri, A., et al. (författare)
  • The high-redshift gamma-ray burst GRB 140515A A comprehensive X-ray and optical study
  • 2015
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 581
  • Tidskriftsartikel (refereegranskat)abstract
    • High-redshift eamma-ray bursts (GRBs) offer several advantages When studying the distant Universe, providing unique information about the structure and properties of the galaxies in which they exploded. Spectroscopic identification with large ground-based telescopes has improved our knowledge of this kind of distant events. We present the multi-wavelength analysis of the high-z S'wift GRB GRB 1.40515A (z = 6.327). The best estimate of the neutral hydrogen fraction of the intergalactic medium towards the burst is X-HI <= 0.002. The spectral absorption lines detected for this event are the weakest lines ever observed in GRB afterglows, suggesting that GRB 140515A exploded in a very low-density environment. Its circtun-burst medium is characterised by an average extinction (A(V) similar to 0.1) that seems to be typical of z >= 6 events. The observed multi-band light curves are explained either with a very hard injected spectrum (p = 1.7) or with a multi-component emission (p = 2.1). In the second case a long-lasting central engine activity is needed in order to explain the late time X-ray emission. The possible origin of GRB 140515A in a Pop III (or in a Pop II star with a local environment enriched by Pop III) massive star is unlikely.
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13.
  • Ho, Anna Y. Q., et al. (författare)
  • Cosmological Fast Optical Transients with the Zwicky Transient Facility : A Search for Dirty Fireballs
  • 2022
  • Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 938:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Dirty fireballs are a hypothesized class of relativistic massive-star explosions with an initial Lorentz factor Γinit below the Γinit ∼ 100 required to produce a long-duration gamma-ray burst (LGRB), but which could still produce optical emission resembling LGRB afterglows. Here we present the results of a search for on-axis optical afterglows using the Zwicky Transient Facility (ZTF). Our search yielded seven optical transients that resemble on-axis LGRB afterglows in terms of their red colors (g − r > 0 mag), faint host galaxies (r > 23 mag), rapid fading (dr/dt > 1 mag day−1), and in some cases X-ray and radio emission. Spectroscopy of the transient emission within a few days of discovery established cosmological distances (redshift z = 0.876 to 2.9) for six of the seven events, tripling the number of afterglows with redshift measurements discovered by optical surveys without a γ-ray trigger. A likely associated LGRB (GRB 200524A, GRB 210204A, GRB 210212B, and GRB 210610B) was identified for four events (ZTF 20abbiixp/AT 2020kym, ZTF 21aagwbjr/AT 2021buv, ZTF 21aakruew/AT 2021cwd, and ZTF 21abfmpwn/AT 2021qbd) post facto, while three (ZTF 20aajnksq/AT 2020blt, ZTF 21aaeyldq/AT 2021any, and ZTF 21aayokph/AT 2021lfa) had no detected LGRB counterpart. The simplest explanation for the three "orphan" events is that they were regular LGRBs missed by high-energy satellites owing to detector sensitivity and duty cycle, although it is possible that they were intrinsically subluminous in γ-rays or viewed slightly off-axis. We rule out a scenario in which dirty fireballs have a similar energy per solid angle to LGRBs and are an order of magnitude more common. In addition, we set the first direct constraint on the ratio of the opening angles of the material producing γ-rays and the material producing early optical afterglow emission, finding that they must be comparable.
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14.
  • Namsolleck, P., et al. (författare)
  • AT2-receptor stimulation enhances axonal plasticity after spinal cord injury by upregulating BDNF expression
  • 2013
  • Ingår i: Neurobiology of Disease. - : Elsevier BV. - 0969-9961 .- 1095-953X. ; 51:SI, s. 177-191
  • Tidskriftsartikel (refereegranskat)abstract
    • It is widely accepted that the angiotensin AT2-receptor (AT2R) has neuroprotective features. In the present study we tested pharmacological AT2R-stimulation as a therapeutic approach in a model of spinal cord compression injury (SCI) in mice using the novel non-peptide AT2R-agonist, Compound 21 (C21). Complementary experiments in primary neurons and organotypic cultures served to identify underlying mechanisms. Functional recovery and plasticity of corticospinal tract (CST) fibers following SCI were monitored after application of C21 (0.3. mg/kg/day. i.p.) or vehicle for 4. weeks. Organotypic co-culture of GFP-positive entorhinal cortices with hippocampal target tissue served to evaluate the impact of C21 on reinnervation. Neuronal differentiation, apoptosis and expression of neurotrophins were investigated in primary murine astrocytes and neuronal cells.C21 significantly improved functional recovery after SCI compared to controls, and this significantly correlated with the increased number of CST fibers caudal to the lesion site. In vitro, C21 significantly promoted reinnervation in organotypic brain slice co-cultures (+50%) and neurite outgrowth of primary neurons (+25%). C21-induced neurite outgrowth was absent in neurons derived from AT2R-KO mice. In primary neurons, treatment with C21 further induced RNA expression of anti-apoptotic Bcl-2 (+75.7%), brain-derived neurotrophic factor (BDNF) (+53.7%), the neurotrophin receptors TrkA (+57.4%) and TrkB (+67.9%) and a marker for neurite growth, GAP43 (+103%), but not TrkC. Our data suggest that selective AT2R-stimulation improves functional recovery in experimental spinal cord injury through promotion of axonal plasticity and through neuroprotective and anti-apoptotic mechanisms. Thus, AT2R-stimulation may be considered for the development of a novel therapeutic approach for the treatment of spinal cord injury.
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15.
  • Thöne, Christina C., et al. (författare)
  • NGC 2770 : A Supernova Ib Factory?
  • 2009
  • Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 698:2, s. 1307-1320
  • Tidskriftsartikel (refereegranskat)abstract
    • NGC 2770 has been the host of three supernovae (SNe) of Type Ib during the last ten years, SN 1999eh, SN 2007uy, and SN 2008D. SN 2008D attracted special attention due to the serendipitous discovery of an associated X-ray transient. In this paper, we study the properties of NGC 2770 and specifically the three SN sites to investigate whether this galaxy is in any way peculiar to cause a high frequency of SNe Ib. We model the global spectral energy distribution of the galaxy from broadband data and derive a star formation and SN rate comparable to the values of the Milky Way. We further study the galaxy using longslit spectroscopy covering the major axis and the three SN sites. From the spectroscopic study we find subsolar metallicities for the SN sites, a high extinction and a moderate star formation rate. In a high-resolution spectrum, we also detect diffuse interstellar bands in the line of sight toward SN 2008D. A comparison of NGC 2770 to the global properties of a galaxy sample with high SN occurrence (>= 3 SN in the last 100 years) suggests that NGC 2770 is not particularly destined to produce such an enhancement of observed SNe. Its properties are also very different from gamma-ray burst host galaxies. Statistical considerations on SN Ib detection rates give a probability of ~1.5% to find a galaxy with three Ib SNe detected in ten years. The high number of rare Ib SNe in this galaxy is therefore likely to be a coincidence rather than special properties of the galaxy itself. NGC 2770 has a small irregular companion, NGC 2770B, which is highly star-forming, has a very low mass and one of the lowest metallicities detected in the nearby universe as derived from longslit spectroscopy. In the most metal poor part, we even detect Wolf-Rayet (WR) features, which is at odds with most current models of WR stars which require high metallicities. Based on observations with the Nordic Optical Telescope, ESO proposal 080.D-0526, the GALEX and NED databases.
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