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- Thomas, HS, et al.
(författare)
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- 2019
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swepub:Mat__t
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- Khatri, C, et al.
(författare)
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Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
- 2021
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Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 11:11, s. e050830-
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Tidskriftsartikel (refereegranskat)abstract
- Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.SettingProspective, international, multicentre, observational cohort study.ParticipantsPatients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.ResultsThis study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p<0.001), age >80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).ConclusionsPatients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration numberNCT04323644
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- Abend, Sven, et al.
(författare)
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Terrestrial very-long-baseline atom interferometry : Workshop summary
- 2024
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Ingår i: AVS Quantum Science. - : American Institute of Physics (AIP). - 2639-0213. ; 6:2
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Forskningsöversikt (refereegranskat)abstract
- This document presents a summary of the 2023 Terrestrial Very-Long-Baseline Atom Interferometry Workshop hosted by CERN. The workshop brought together experts from around the world to discuss the exciting developments in large-scale atom interferometer (AI) prototypes and their potential for detecting ultralight dark matter and gravitational waves. The primary objective of the workshop was to lay the groundwork for an international TVLBAI proto-collaboration. This collaboration aims to unite researchers from different institutions to strategize and secure funding for terrestrial large-scale AI projects. The ultimate goal is to create a roadmap detailing the design and technology choices for one or more kilometer--scale detectors, which will be operational in the mid-2030s. The key sections of this report present the physics case and technical challenges, together with a comprehensive overview of the discussions at the workshop together with the main conclusions.
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- Ao, Y., et al.
(författare)
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The thermal state of molecular clouds in the Galactic center: evidence for non-photon-driven heating
- 2014
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Ingår i: Proceedings of the International Astronomical Union. - 1743-9213 .- 1743-9221. ; 9:S303, s. 89-91
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Tidskriftsartikel (refereegranskat)abstract
- We have used the Atacama Pathfinder Experiment (APEX) 12 m telescope at 218 GHz to observe molecular clouds simultaneously in the J_KA,Kc=3_03→2_02,3_22→2_21,and 3_21→2_20 transitions of para-H2CO to determine kinetic temperatures of the dense gas in the central molecular zone of the Galaxy. Gas kinetic temperatures for individual molecular clouds range from 55 to 125 K or even higher. The molecular clouds at high temperatures may be heated by turbulent dissipation and/or cosmic-rays
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- Ao, Y., et al.
(författare)
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The thermal state of molecular clouds in the Galactic center: evidence for non-photon-driven heating
- 2013
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 550
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Tidskriftsartikel (refereegranskat)abstract
- We used the Atacama Pathfinder Experiment (APEX) 12 m telescope to observe the J(KAKc) = 3(03) -> 2(02), 3(22) -> 2(21), and 3(21) -> 2(20) transitions of para-H2CO at 218 GHz simultaneously to determine kinetic temperatures of the dense gas in the central molecular zone (CMZ) of our Galaxy. The map extends over approximately 40' x 8' (similar to 100 x 20 pc(2)) along the Galactic plane with a linear resolution of 1.2 pc. The strongest of the three lines, the H2CO (3(03) -> 2(02)) transition, is found to be widespread, and its emission shows a spatial distribution similar to ammonia. The relative abundance of para-H2CO is 0.5 - 1.2 x 10(-9), which is consistent with results from lower frequency H2CO absorption lines. Derived gas kinetic temperatures for individual molecular clouds range from 50K to values in excess of 100 K. While a systematic trend toward (decreasing) kinetic temperature versus (increasing) angular distance from the Galactic center (GC) is not found, the clouds with highest temperature (T-kin > 100 K) are all located near the nucleus. For the molecular gas outside the dense clouds, the average kinetic temperature is 65 +/- 10 K. The high temperatures of molecular clouds on large scales in the GC region may be driven by turbulent energy dissipation and / or cosmic-rays instead of photons. Such a non-photon-driven thermal state of the molecular gas provides an excellent template for the more distant vigorous starbursts found in ultraluminous infrared galaxies (ULIRGs).
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- Ginsburg, A., et al.
(författare)
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Dense gas in the Galactic central molecular zone is warm and heated by turbulence
- 2016
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 586, s. Art nr A50-
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Tidskriftsartikel (refereegranskat)abstract
- Context. The Galactic center is the closest region where we can study star formation under extreme physical conditions like those in high-redshift galaxies. Aims. We measure the temperature of the dense gas in the central molecular zone (CMZ) and examine what drives it. Methods. We mapped the inner 300 pc of the CMZ in the temperature-sensitive J = 3-2 para-formaldehyde (p-H2CO) transitions. We used the 3(2,1)-2(2,0)/3(0,3)-2(0,2) line ratio to determine the gas temperature in n similar to 10(4) - 10(5) cm(-3) gas. We have produced temperature maps and cubes with 30 0 0 and 1 km s(-1) resolution and published all data in FITS form. Results. Dense gas temperatures in the Galactic center range from similar to 60 K to > 100 K in selected regions. The highest gas temperatures T-G > 100 K are observed around the Sgr B2 cores, in the extended Sgr B2 cloud, the 20 km s(-1) and 50 km s(-1) clouds, and in "The Brick" (G0.253 + 0.016). We infer an upper limit on the cosmic ray ionization rate zeta(CR)
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