| 1. |
- Weinstein, John N., et al.
(författare)
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The cancer genome atlas pan-cancer analysis project
- 2013
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 45:10, s. 1113-1120
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Forskningsöversikt (refereegranskat)abstract
- The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile. © 2013 Nature America, Inc. All rights reserved.
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| 2. |
- Lixing, Zhou, et al.
(författare)
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Understanding dipole formation at dielectric/dielectric hetero-interface
- 2018
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Ingår i: Applied Physics Letters. - : AIP Publishing. - 0003-6951 .- 1077-3118. ; 113:18
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Tidskriftsartikel (refereegranskat)abstract
- Band alignment and dipole formation at the hetero-interface still remain fascinating and, hence, are being intensively investigated. In this study, we experimentally investigate the dipole formation by employing a dielectric/dielectric (Al2O3/GeO2) interface. We investigate the dipole dependence on various post-deposition annealing (PDA) ambiences from the viewpoints of electrical extraction and the X-ray photoelectron spectroscopy measurement. The core level shift at the Al2O3/GeO2 interface is consistent with the dipole changes in various PDA ambiences. We discover that the dipole formation can be well explained by the interface gap state and charge neutrality level theory. These results further confirm the feasibility of gap state theory in explaining the band alignment at hetero-junctions. This study can be a booster to enhance the comprehension of dipole origin at hetero-junction interfaces.
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| 3. |
- Zhang, Chuntian, et al.
(författare)
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Integrated optimization of train scheduling and maintenance planning on high-speed railway corridors
- 2019
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Ingår i: Omega. - : Elsevier. - 0305-0483 .- 1873-5274. ; 87, s. 86-104
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Tidskriftsartikel (refereegranskat)abstract
- Regular maintenances on high-speed railway facilities are performed in every night in China, and during regular maintenances, high-speed railway is not available for the sunset-departure and sunrise-arrival trains (SDSA-trains). In order to reduce the influence of regular maintenances on SDSA-trains, three operation modes are used in practice, which mainly consist of route selections between high-speed railway and normal-speed railway. In this paper, we use some linearization techniques to formulate a mixed integer linear programming (MILP) model to identify the operation modes and the timetable of SDSA-trains, by integrating the time window selection of regular maintenances on high-speed railways. The objective of the model is to minimize the total travel time of SDSA-trains. In the formulation of the model, we introduce state variables to indicate whether a train is running on high-speed railway or not, which makes it conveniently express the selection of operation modes. Based on the real data of Beijing-Guangzhou high-speed and normal-speed railway corridors in China, numerical experiments are carried out to test the proposed model and optimization method.
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