| 1. |
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| 2. |
- Klionsky, Daniel J., et al.
(författare)
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Guidelines for the use and interpretation of assays for monitoring autophagy
- 2012
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Ingår i: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 8:4, s. 445-544
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Forskningsöversikt (refereegranskat)abstract
- In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field.
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| 3. |
- Abelev, Betty, et al.
(författare)
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Long-range angular correlations on the near and away side in p-Pb collisions at root S-NN=5.02 TeV
- 2013
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Ingår i: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 719:1-3, s. 29-41
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Tidskriftsartikel (refereegranskat)abstract
- Angular correlations between charged trigger and associated particles are measured by the ALICE detector in p-Pb collisions at a nucleon-nucleon centre-of-mass energy of 5.02 TeV for transverse momentum ranges within 0.5 < P-T,P-assoc < P-T,P-trig < 4 GeV/c. The correlations are measured over two units of pseudorapidity and full azimuthal angle in different intervals of event multiplicity, and expressed as associated yield per trigger particle. Two long-range ridge-like structures, one on the near side and one on the away side, are observed when the per-trigger yield obtained in low-multiplicity events is subtracted from the one in high-multiplicity events. The excess on the near-side is qualitatively similar to that recently reported by the CMS Collaboration, while the excess on the away-side is reported for the first time. The two-ridge structure projected onto azimuthal angle is quantified with the second and third Fourier coefficients as well as by near-side and away-side yields and widths. The yields on the near side and on the away side are equal within the uncertainties for all studied event multiplicity and p(T) bins, and the widths show no significant evolution with event multiplicity or p(T). These findings suggest that the near-side ridge is accompanied by an essentially identical away-side ridge. (c) 2013 CERN. Published by Elsevier B.V. All rights reserved.
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| 4. |
- Abelev, Betty, et al.
(författare)
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Measurement of prompt J/psi and beauty hadron production cross sections at mid-rapidity in pp collisions at root s=7 TeV
- 2012
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Ingår i: Journal of High Energy Physics. - 1029-8479. ; :11
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Tidskriftsartikel (refereegranskat)abstract
- The ALICE experiment at the LHC has studied J/psi production at mid-rapidity in pp collisions at root s = 7 TeV through its electron pair decay on a data sample corresponding to an integrated luminosity L-int = 5.6 nb(-1). The fraction of J/psi from the decay of long-lived beauty hadrons was determined for J/psi candidates with transverse momentum p(t) > 1,3 GeV/c and rapidity vertical bar y vertical bar < 0.9. The cross section for prompt J/psi mesons, i.e. directly produced J/psi and prompt decays of heavier charmonium states such as the psi(2S) and chi(c) resonances, is sigma(prompt J/psi) (p(t) > 1.3 GeV/c, vertical bar y vertical bar < 0.9) = 8.3 +/- 0.8(stat.) +/- 1.1 (syst.)(-1.4)(+1.5) (syst. pol.) mu b. The cross section for the production of b-hadrons decaying to J/psi with p(t) > 1.3 GeV/c and vertical bar y vertical bar < 0.9 is a sigma(J/psi <- hB) (p(t) > 1.3 GeV/c, vertical bar y vertical bar < 0.9) = 1.46 +/- 0.38 (stat.)(-0.32)(+0.26) (syst.) mu b. The results are compared to QCD model predictions. The shape of the p(t) and y distributions of b-quarks predicted by perturbative QCD model calculations are used to extrapolate the measured cross section to derive the b (b) over bar pair total cross section and d sigma/dy at mid-rapidity.
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| 5. |
- Birney, Ewan, et al.
(författare)
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
- 2007
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 447:7146, s. 799-816
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Tidskriftsartikel (refereegranskat)abstract
- We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE Project. These data have been further integrated and augmented by a number of evolutionary and computational analyses. Together, our results advance the collective knowledge about human genome function in several major areas. First, our studies provide convincing evidence that the genome is pervasively transcribed, such that the majority of its bases can be found in primary transcripts, including non-protein-coding transcripts, and those that extensively overlap one another. Second, systematic examination of transcriptional regulation has yielded new understanding about transcription start sites, including their relationship to specific regulatory sequences and features of chromatin accessibility and histone modification. Third, a more sophisticated view of chromatin structure has emerged, including its inter-relationship with DNA replication and transcriptional regulation. Finally, integration of these new sources of information, in particular with respect to mammalian evolution based on inter- and intra-species sequence comparisons, has yielded new mechanistic and evolutionary insights concerning the functional landscape of the human genome. Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function.
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| 6. |
- Zhao, Chaoyang, et al.
(författare)
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A massive expansion of effector genes underlies gall-formation in the wheat pest Mayetiola destructor
- 2015
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Ingår i: Current Biology. - : Elsevier BV. - 1879-0445 .- 0960-9822. ; 25:5, s. 613-620
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Tidskriftsartikel (refereegranskat)abstract
- Gall-forming arthropods are highly specialized herbivores that, in combination with their hosts, produce extended phenotypes with unique morphologies [1]. Many are economically important, and others have improved our understanding of ecology and adaptive radiation [2]. However, the mechanisms that these arthropods use to induce plant galls are poorly understood. We sequenced the genome of the Hessian fly (Mayetiola destructor; Diptera: Cecidomyiidae), a plant parasitic gall midge and a pest of wheat (Triticum spp.), with the aim of identifying genic modifications that contribute to its plant-parasitic lifestyle. Among several adaptive modifications, we discovered an expansive reservoir of potential effector proteins. Nearly 5% of the 20,163 predicted gene models matched putative effector gene transcripts present in the M. destructor larval salivary gland. Another 466 putative effectors were discovered among the genes that have no sequence similarities in other organisms. The largest known arthropod gene family (family SSGP-71) was also discovered within the effector reservoir. SSGP-71 proteins lack sequence homologies to other proteins, but their structures resemble both ubiquitin E3 ligases in plants and E3-ligase-mimicking effectors in plant pathogenic bacteria. SSGP-71 proteins and wheat Skp proteins interact in vivo. Mutations in different SSGP-71 genes avoid the effector-triggered immunity that is directed by the wheat resistance genes H6 and H9. Results point to effectors as the agents responsible for arthropod-induced plant gall formation.
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| 7. |
- Abelev, Betty, et al.
(författare)
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Underlying Event measurements in pp collisions at root s=0.9 and 7 TeV with the ALICE experiment at the LHC
- 2012
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Ingår i: Journal of High Energy Physics. - 1029-8479. ; :7
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Tidskriftsartikel (refereegranskat)abstract
- We present measurements of Underlying Event observables in pp collisions at root s = 0 : 9 and 7 TeV. The analysis is performed as a function of the highest charged-particle transverse momentum p(T),L-T in the event. Different regions are defined with respect to the azimuthal direction of the leading (highest transverse momentum) track: Toward, Transverse and Away. The Toward and Away regions collect the fragmentation products of the hardest partonic interaction. The Transverse region is expected to be most sensitive to the Underlying Event activity. The study is performed with charged particles above three different p(T) thresholds: 0.15, 0.5 and 1.0 GeV/c. In the Transverse region we observe an increase in the multiplicity of a factor 2-3 between the lower and higher collision energies, depending on the track p(T) threshold considered. Data are compared to PYTHIA 6.4, PYTHIA 8.1 and PHOJET. On average, all models considered underestimate the multiplicity and summed p(T) in the Transverse region by about 10-30%.
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| 8. |
- Al Karim, Miftah, et al.
(författare)
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Synchrophasor-based data mining for power system fault analysis
- 2012
-
Ingår i: Innovative Smart Grid Technologies (ISGT Europe), 2012 3rd IEEE PES International Conference and Exhibition on. - : IEEE. - 9781467325974 ; , s. 6465843-
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Konferensbidrag (refereegranskat)abstract
- Phasor measurement units can provide high resolution and synchronized power system data, which can be effectively utilized for the implementation of data mining techniques. Data mining, based on pattern recognition algorithms can be of significant help for power system analysis, as high definition data is often complex to comprehend. In this paper three pattern recognition algorithms are applied to perform the data mining tasks. The deployment is carried out firstly for fault data classification, secondly for checking which faults are occurring more frequently and thirdly for identifying the root cause of a fault by clustering the parameters behind each scenario. For such purposes three algorithms are chosen, k-Nearest Neighbor, Naïve Bayes and the k-means Clustering.
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| 9. |
- Babazadeh, Davood, et al.
(författare)
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A Platform for Wide Area Monitoring and Control System ICT Analysis and Development
- 2013
-
Ingår i: 2013 IEEE Grenoble Conference PowerTech, POWERTECH 2013. - : IEEE. - 9781467356695
-
Konferensbidrag (refereegranskat)abstract
- PMU-based Wide Area Monitoring and Control(WAMC) system is introduced to improve the monitoring ofpower grid across large geographic areas and control the gridusing more efficient and smart applications. The performance ofWAMC applications in real power system scenarios and impactof their supporting Information and Communication Technology(ICT) on the data quality can be quantified and analyzed bypseudo-real co-simulation test beds. The purpose of this study isto propose and develop a WAMC testing platform to facilitate thereal-time simulation of dynamic power grid, the ICTinfrastructure that overlays the grid and WAMS applications.The platform consists of OPNET, a powerful communicationnetwork emulator, connected to a real-time power systemsimulator through virtualized PMU device. The end pointstations such as Phasor Data Concentrator or PMU-basedapplications are also linked to the platform through OPNET’sreal-simulation gateway called SITL (System-In-The-Loop). Toassess the performance of the platform architecture, a case studyhas been performed with five PMUs which collect the data from apower model and deliver to PMU-based mode-estimationapplication over a typical communication network. In this study,the results explicitly intend to quantify the effect of networkprotocols on data delay.
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| 10. |
- Babazadeh, Davood, et al.
(författare)
-
Real-Time Smart Grid Application Testing using OPNET SITL
- 2012
-
Konferensbidrag (refereegranskat)abstract
- Phasor -based Wide Area Monitoring and Control (WAMC) system promise to improve the monitoring of power grid across large geographic areas and accordingly controlling grid in more efficient and intelligent ways. In order to have confidence on the correctness, performance and reliability of applications used in WAMC system in real world scenarios, pseudo-real test beds where the requirements for the applications and their supporting Information and Communication Technology (ICT) can be quantified and analyzed. In this paper, a WAMC system testing platform is proposed to facilitate the real-time simulation of dynamic power grid, the ICT infrastructure that overlays the grid and WAMC applications. The proposed platform consists of OPNET as a powerful communication network simulator connected to real-time power system simulator on one side through virtualized Phasor Measurement Unit device, and linked to end point stations such as Phasor Data Concentrator or application on the other side through OPNET’s real-simulation gateway. A set of proof of concept scenarios using this framework is presented.
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| 11. |
- Badr, Hussein O., et al.
(författare)
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Bottom-up, scalable synthesis of anatase nanofilament-based two-dimensional titanium carbo-oxide flakes
- 2022
-
Ingår i: Materials Today. - : ELSEVIER SCI LTD. - 1369-7021 .- 1873-4103. ; 54
-
Tidskriftsartikel (refereegranskat)abstract
- Two-dimensional (2D) materials offer advantages that their 3D counterparts do not. The conventional method for the bulk synthesis of 2D materials has predominantly been through etching layered solids. Herein, we convert - through a bottom-up approach - 10 binary and ternary titanium carbides, nitrides, borides, phosphides, and silicides into 2D flakes by immersing them in a tetramethylammonium hydroxide solution at temperatures in the 25-85 degrees C range. Based on X-ray diffraction, density functional theory, X-ray photoelectron, electron energy loss, Raman, X-ray absorption near edge structure spectroscopies, transmission and scanning electron microscope images and selected area diffraction, we conclude that the resulting flakes are carbon containing anatase-based layers that are, in turn, comprised of approximate to 6 x 10 angstrom(2) nanofilaments in cross-section some of which are few microns long. Electrodes made from some of these films performed well in lithium-ion and lithium-sulphur systems. These materials also reduce the viability of cancer cells thus showing potential in biomedical applications. Synthesizing 2D materials, at near ambient conditions, with non-layered, inexpensive, green precursors (e.g., TiC) is paradigm shifting and will undoubtedly open new and exciting avenues of research and applications.
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| 12. |
- Björkman, Gunnar, et al.
(författare)
-
SCADA system architectures
- 2010
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- The aim of deliverable 2.3 in the VIKING is to catalogue architecture patterns or reference architectures, i.e. commonly deployed solutions, for SCADA systems. These patterns are represented as a set of descriptions that capture the vast majority of SCADA systems’ architecture on a high level. The patterns developed in this report focus on: - Software services in SCADA systems and software services which SCADA systems exchange data with. - Data flows among these services. - How services are placed in different security zones (network zones). The purpose of the SCADA architecture patterns is to clarify how SCADA systems are commonly designed by employing a stringent model framework. Internal in the project the SCADA patterns will be used to develop SCADA system design models that reflect some typical systems deployed in industry. These models will be used in other work packages and deliverables in the VIKING project.
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| 13. |
- Bottura, Riccardo, et al.
(författare)
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SITL and HLA Co-simulation Platforms : Tools for Analysis of the Integrated ICT and Electric Power System
- 2013
-
Ingår i: 2013 IEEE EUROCON. - 9781467322300
-
Konferensbidrag (refereegranskat)abstract
- Due to the necessity of developing analysis tools inthe integrated ICT and power system domain, this paperdescribes and compares the architecture and configuration oftwo different co-simulation approaches called SITL and HLACo-simulation platforms. We provide several details on theirimplementation and present their features by means of theresults obtained for two test cases. The paper aims at clarifyingthe type of analysis that can be effectively carried out by usingthe two different platforms. Both platforms make use of thecommunication network simulator OPNET (Optimum NetworkPerformance). One of the two platforms operates in real time, inorder to perform system-in-the-loop (SITL) simulations. Theother platform is based on the interface between OPNET and thepower network simulation environment EMTP (ElectromagneticTransient Program). The interface is based on the application ofthe High-Level Architecture (HLA) standard.
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| 14. |
- Chen, Fangjun, et al.
(författare)
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Comprehensive kinetic modeling and product distribution for pyrolysis of pulp and paper mill sludge
- 2024
-
Ingår i: Science of the Total Environment. - 0048-9697 .- 1879-1026. ; 924
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Tidskriftsartikel (refereegranskat)abstract
- Pyrolysis holds immense potential for clean treatment of pulp and paper mill sludge (PPMS), enabling efficient energy and chemical recovery. However, current understanding of PPMS pyrolysis kinetics and product characteristics remains incomplete. This study conducted detailed modeling of pyrolysis kinetics for two typical PPMSs from a wastepaper pulp and paper mill, namely, deinking sludge (PPMS-DS) and sewage sludge (PPMS-SS), and analyzed comprehensively pyrolysis products. The results show that apparent activation energy of PPMS-DS (169.25–226.82 kJ/mol) and PPMS-SS (189.29–411.21 kJ/mol) pyrolysis undergoes significant change, with numerous parallel reactions present. A distributed activation energy model with dual logistic distributions proves to be suitable for modeling thermal decomposition kinetics of both PPMS-DS and PPMS-SS, with coefficient of determination >0.999 and relative root mean square error <1.99 %. High temperature promotes decomposition of solid organic materials in PPMS, and maximum tar yield for both PPMS-DS (53.90 wt%, daf) and PPMS-SS (56.48 wt%, daf) is achieved at around 500 °C. Higher levels of styrene (24.45 % for PPMS-DS and 14.71 % for PPMS-SS) and ethylbenzene (8.61 % for PPMS-DS and 8.33 % for PPMS-SS) are detected in tar and could be used as chemicals. This work shows great potential to propel development of PPMS pyrolysis technology, enabling green and sustainable production in pulp and paper industry.
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| 15. |
- Chen, Hui, et al.
(författare)
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Characterization of insolubilized humic acid and its sorption behaviors
- 2009
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Ingår i: Environmental Geology. - : Springer Science and Business Media LLC. - 0943-0105 .- 1432-0495. ; 57:8, s. 1847-1853
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Tidskriftsartikel (refereegranskat)abstract
- Insolubilized humic acid (IHA) was prepared in the laboratory by heating approach. Through the comparison between the endothermic peaks, optimal heating temperature was determined to be 330A degrees C. The modified IHA then was characterized by TG-DTA, SEM, FTIR, element analysis, and nitrogen adsorption-desorption isotherms. The removal efficiency of p-nitrophenol from the aqueous solution by adsorption onto solid IHA surfaces was shown to be a function of pH, reaction temperature, and p-nitrophenol concentration. Adsorption equilibrium data satisfactorily fitted the Langmuir adsorption isotherm. Under a certain concentration range, the removal rate of p-nitrophenol at pH 3.5 could reach 24, 29, and 35 mg/g at a temperature of 25, 35, and 45 +/- 0.1A degrees C. The results suggest that IHA could play a role as a potential efficient absorbent to remove organic contaminants, e.g., utilized to purify water contaminated by organic compounds.
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| 16. |
- Chenine, Moustafa, et al.
(författare)
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Survey on Priorities and Communication Requirements for PMU-based Applications in the Nordic Region
- 2009
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Ingår i: 2009 IEEE Bucharest PowerTech. - : IEEE. - 9781424422340 ; , s. 1183-1190
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Konferensbidrag (refereegranskat)abstract
- Phasor based Wide Area Monitoring and Control Systems (WAMC) promise to offer more accurate and timely data on the state of the power system, thus, increasing the possibilities to manage the system at a more efficient and responsive level and apply wide area control and protection schemes. This paper presents results of a survey on communications and technical requirements for applications based on Phasor Measurement Units (PMU). The survey was carried out in the Nordic Region with participants from Transmission System Operators (TSOs) and researchers. The survey focused on documenting the stage of research and development among TSOs and researchers in the Nordic Region, as well as, their plans and visions for the future. This includes planned PMU deployments and prioritization of PMU based applications. Furthermore, a significant part of the survey was an elicitation of communication requirements for applications based on PMU data. In the paper, an examination of the time requirements for these applications in terms of delays and samples per second and comparison similar published specifications is provided.
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| 17. |
- Ehlers, Todd A., et al.
(författare)
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Past, present, and future geo-biosphere interactions on the Tibetan Plateau and implications for permafrost
- 2022
-
Ingår i: Earth-Science Reviews. - : Elsevier BV. - 0012-8252. ; 234
-
Tidskriftsartikel (refereegranskat)abstract
- Interactions between the atmosphere, biosphere, cryosphere, hydrosphere, and geosphere are most active in the critical zone, a region extending from the tops of trees to the top of unweathered bedrock. Changes in one or more of these spheres can result in a cascade of changes throughout the system in ways that are often poorly understood. Here we investigate how past and present climate change have impacted permafrost, hydrology, and ecosystems on the Tibetan Plateau. We do this by compiling existing climate, hydrologic, cryosphere, biosphere, and geologic studies documenting change over decadal to glacial-interglacial timescales and longer. Our emphasis is on showing present-day trends in environmental change and how plateau ecosystems have largely flourished under warmer and wetter periods in the geologic past. We identify two future pathways that could lead to either a favorable greening or unfavorable degradation and desiccation of plateau ecosystems. Both paths are plausible given the available evidence. We contend that the key to which pathway future generations experience lies in what, if any, human intervention measures are implemented. We conclude with suggested management strategies that can be implemented to facilitate a future greening of the Tibetan Plateau.
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| 18. |
- Estrada, Karol, et al.
(författare)
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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
- 2012
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Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 44:5, s. 491-501
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Tidskriftsartikel (refereegranskat)abstract
- Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 genome-wide association studies and 32,961 individuals of European and east Asian ancestry. We tested the top BMD-associated markers for replication in 50,933 independent subjects and for association with risk of low-trauma fracture in 31,016 individuals with a history of fracture (cases) and 102,444 controls. We identified 56 loci (32 new) associated with BMD at genome-wide significance (P < 5 × 10(-8)). Several of these factors cluster within the RANK-RANKL-OPG, mesenchymal stem cell differentiation, endochondral ossification and Wnt signaling pathways. However, we also discovered loci that were localized to genes not known to have a role in bone biology. Fourteen BMD-associated loci were also associated with fracture risk (P < 5 × 10(-4), Bonferroni corrected), of which six reached P < 5 × 10(-8), including at 18p11.21 (FAM210A), 7q21.3 (SLC25A13), 11q13.2 (LRP5), 4q22.1 (MEPE), 2p16.2 (SPTBN1) and 10q21.1 (DKK1). These findings shed light on the genetic architecture and pathophysiological mechanisms underlying BMD variation and fracture susceptibility.
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| 19. |
- Franke, Ulrik, et al.
(författare)
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Enterprise Architecture analysis using Fault Trees and MODAF
- 2009
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Ingår i: Proceedings of the Forum at the CAiSE 2009 Conference. ; , s. 61-66
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Konferensbidrag (refereegranskat)abstract
- Analysis of dependencies between information systems, business processes, and strategic goals is an important part of the discipline of Enterprise Architecture (EA). However, EA models typically provide only visual and qualitative decision support. This paper shows how EA frameworks for dependency analysis can be extended into the realm of quantitative methods by the use of techniques from Fault Tree Analysis (FTA). Using MODAF, the UK Ministry of Defence Architecture Framework as an example, we give a list of criteria for the extraction of a metamodel for FTA use, and provide such a metamodel for MODAF. Furthermore, we use this MODAF FTA metamodel to perform dependency analysis on a sample MODAF model.
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| 20. |
- Fu, Hongyan, et al.
(författare)
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Tunable all-optical microwave notch filter with a negative tap based on a semiconductor optical amplifier and a dispersive medium
- 2009
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Ingår i: Optics and Laser Technology. - : Elsevier BV. - 0030-3992 .- 1879-2545. ; 41:3, s. 213-216
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Tidskriftsartikel (refereegranskat)abstract
- A tunable all-optical microwave notch filter with a negative tap based on a semiconductor optical amplifier and a dispersive medium is demonstrated. A negative tap is realized through the cross gain modulation in the semiconductor optical amplifier. The free spectrum range of the notch filter can be tuned by tuning the wavelength of one of the two laser sources. The influence of the amplitude mismatch of the two lasers on the performance of the filter is analyzed. The present notch filter is easy to implement and cost-effective.
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| 21. |
- Han, Xue, et al.
(författare)
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Empirical analysis for Distributed Energy Resources' impact on future distribution network
- 2012
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Ingår i: Energy Conference and Exhibition (ENERGYCON), 2012 IEEE International. - : IEEE. - 9781467314541 ; , s. 731-737
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Konferensbidrag (refereegranskat)abstract
- There has been a large body of statements claiming that the large scale deployment of Distributed Energy Resources (DERs) will eventually reshape the future distribution grid operation in various ways. Thus, it is interesting to introduce a platform to interpret to what extent the power system operation will be alternated. In this paper, quantitative results in terms of how the future distribution grid will be changed by the deployment of distributed generation, active demand and electric vehicles, are presented. The analysis is based on the conditions for both a radial and a meshed distribution network. The input parameters are based on the current and envisioned DER deployment scenarios proposed for Sweden.
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| 22. |
- Han, Xue, et al.
(författare)
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Modelling Framework and the Quantitative Analysis of Distributed Energy Resources in Future Distribution Networks
- 2013
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Ingår i: International Journal of Emerging Electric Power Systems. - : De Gruyter. - 2194-5756 .- 1553-779X. ; 14:5, s. 421-431
-
Tidskriftsartikel (refereegranskat)abstract
- There has been a large body of statements claiming that the large-scale deployment of Distributed Energy Resources (DERs) could eventually reshape the future distribution grid operation in numerous ways. Thus, it is necessary to introduce a framework to measure to what extent the power system operation will be changed by various parameters of DERs. This article proposed a modelling framework for an overview analysis on the correlation between DERs. Furthermore, to validate the framework, the authors described the reference models of different categories of DERs with their unique characteristics, comprising distributed generation, active demand and electric vehicles. Subsequently, quantitative analysis was made on the basis of the current and envisioned DER deployment scenarios proposed for Sweden. Simulations are performed in two typical distribution network models for four seasons. The simulation results show that in general the DER deployment brings in the possibilities to reduce the power losses and voltage drops by compensating power from the local generation and optimizing the local load profiles.
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| 23. |
- He, Shu, et al.
(författare)
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A global assay of haemostasis which uses recombinant tissue factor and tissue-type plasminogen activator to measure the rate of fibrin formation and fibrin degradation in plasma
- 2007
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Ingår i: Thrombosis and Haemostasis. - 0340-6245 .- 2567-689X. ; 98:4, s. 871-882
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Tidskriftsartikel (refereegranskat)abstract
- The global assay of Overall Haemostasis Potential we previously described has been refined. The coagulation cascade in platelet-poor plasma is triggered by adding a minimal dose of recombinant tissue factor together with purified phospholipids and calcium; fibrinolysis is initiated by adding recombinant tissue type-plasminogen activator in a concentration similar to what can be obtained during thrombolysis. Numerical differentials of optical densities reflecting rates of fibrin formation and degradation are calculated by a new software, and the Coagulation Profile (Cp) and the Fibrinolysis Profile (Fp) are determined. The combined effect of these counteractive systems is expressed as a ratio of Cp to Fp, called the Overall Haemostasis Index. Commercially available coagulant-deficient patient plasma samples and plasma with various amounts of added PAI-1 are examined; changes of fibrin turbidity demonstrate that this assay can determine Cp and Fp in a physiologically relevant way. Increased Cp and decreased Fp in prothrombotic patients, as well as expected effects of heparin or a thrombin inhibitor on Cp and Fp, suggest that our method can detect hypercoagulability and assist in monitoring antithrombotic treatment. Ongoing studies will show whether this simple assay can be of value in clinical routine.
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| 24. |
- Honeth, Nicholas, et al.
(författare)
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Decentralized topology inference of electrical distribution networks
- 2012
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Ingår i: 2012 IEEE PES Innovative Smart Grid Technologies, ISGT 2012. - : IEEE. - 9781457721588
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Konferensbidrag (refereegranskat)abstract
- Power system operation and control relies heavily on models for decision making. Topology is a critical part of producing these models and maintaining up-to-date topologies of electrical distribution networks is a resource consuming and challenging task. This paper proposes a methodology and system architecture for inference of electrical topology using process and model data from IEC 61850 compliant substation automation devices. A system of autonomous intelligent agents communicating via an overlay network is proposed where agents are capable of communicating on the IEC 61850 station bus. An algorithm for topology inference using structured exchange and comparison of process and model information is developed. The capabilities of structured information exchange and interfacing of substation automation devices enables plug-and-play operation of the topology inference requiring minimal prior knowledge of electrical network structure. Decentralized topology inference forms the basis for future work in operation and management of active distribution networks.
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| 25. |
- König, Johan, et al.
(författare)
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Mapping the Substation Configuration Language of IEC 61850 to ArchiMate
- 2010
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Ingår i: Proceedings - IEEE International Enterprise Distributed Object Computing Workshop, EDOC. - : IEEE. - 9780769541648 ; , s. 60-68
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Konferensbidrag (refereegranskat)abstract
- This paper presents a mapping between the Enterprise Architecture framework ArchiMate and the Substation Configuration Language (SCL) of IEC 61850. Enterprise Architecture (EA) is a discipline for managing an enterprise's information system portfolio in relation to the supported business. Metamodels, descriptive models on how to model and one of the core components of EA, can assist stakeholders in many ways, for example in decision-making. Moreover, the power industry is a domain with an augmented reliance on the support of information systems. IEC 61850 is a standard for the design of Substation Automation (SA) systems and provides a vendor independent framework for interoperability by defining communication networks and functions. The SCL is a descriptive language in IEC 61850 on the configuration of substation Intelligent Electronic Devices (IED) which describes the structure together with physical components and their relating functions. By using SCL, which models the architecture of SA systems, and mapping it to ArchiMate, stakeholders are assisted in understanding their SA system and its architecture. The mapping is intended to support the integration of SA systems applying IEC 61850 into the enterprise architecture. The mapping is demonstrated with an example applying the mapping to a SA configuration based on SCL.
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