| 1. |
- Archer, Trevor, 1949, et al.
(författare)
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Cognitive benefits of exercise intervention
- 2016
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Ingår i: Clinica Terapeutica. - 0009-9074 .- 1972-6007. ; 167:6, s. 180-185
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Tidskriftsartikel (refereegranskat)abstract
- © Società Editrice Universo (SEU).Exercise, as a potent epigenetic regulator, implies the potential to counteract pathophysiological processes and alterations in most cardiovascular/respiratory cells and tissues not withstanding a paucity of understanding the underlying molecular mechanisms and doseresponse relationships. In the present account, the assets accruing from physical exercise and its influence upon executive functioning are examined. Under conditions of neuropsychiatric and neurologic ill-health, age-related deterioration of functional and biomarker indicators during healthy and disordered trajectories, neuroimmune and affective unbalance, and epigenetic pressures, exercise offers a large harvest of augmentations in health and well-being. Both animal models and human studies support the premise of manifest gains from regular exercise within several domains, besides cognitive function and mood, notably as the agency of a noninvasive, readily available therapeutic intervention.
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| 2. |
- Corsi, M., et al.
(författare)
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Cognitive disability in alzheimer's disease and its management
- 2016
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Ingår i: Clinica Terapeutica. - 0009-9074. ; 167:5, s. 123-126
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Cognitive disability linked to neurodegenerative diseases and in particular to Alzheimer's disease, remains an increasing cause for concern through a dramatic prevalence increment and associated socioeconomic burdens. Initially Alzheimer's disease develops asymptomatically with primary clinical signs, such as memory impairment, decline of spatial and perceptual abilities, occurring at a later stage. This delay implies the possibility of promoting early interventions during the pre-symptomatic stage of the disease. Different strategies have been applied in order to prevent/delay onset of Alzheimer's disease or at least to improve quality of life and health conditions of Alzheimer's disease patients and their caregivers, especially in the absence of current viable therapies. Multidomain interventions, aimed at affecting several risk factors simultaneously, offer a versatility that may attain improved outcomes in comparison with single-domain prevention trials. These multidomain interventions involve diet, physical exercise, cognitive training and social activities, while music therapy, improving self-consciousness and reducing neurofibrils, may contribute to deceleration/delay onset of Alzheimer's disease progression. Information and Communication Technology (ICT) provides broad applications to improve quality of life and well-being of Alzheimer's disease patients and caregivers, suffering from psychological distress, as well as reducing additional public health costs.
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| 3. |
- Crusco, M., et al.
(författare)
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Gambling and the need for new responses in Public Health with an addiction "sine substantia"
- 2016
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Ingår i: Clinica Terapeutica. - 0009-9074. ; 167:6
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Background. The Gambling Disorder (GD) was recently defined as a behavioral addiction by the "The Diagnostic and Statistical Manual of Mental Disorders IV"(DSM-V) since the clinical, neurobiological and psychopathological similarities led it to be defined it as an addiction "sine substantia". The aim of this study is to formulate an "identikit" of the gambler, to evaluate a possible association between GD/emotional specific factors and the correlation between GD/substance abuse, GD/suicide. Method. In the study, 41 subjects were included (31 males and 10 females) and all were diagnosed with GD. A questionnaire was distributed containing 24 questions deriving from South Oaks Gambling Screen and the DSM-IVTR. Results. The study showed that 51% of the respondents makes use of alcohol and/or drugs; that 73% of the patients started playing in order to relieve feelings of dysphoria and suffering consequences on work as well as family life (51%). A great deal of the respondents were indebted (39%) to the extent of needing to ask for loans from usurer (17%). Furthermore, 41% of the respondents in the sample showed that GD could be transformed into an alarming risk of suicide. Discussion. The correlation between GD and drug abuse may depend on the brain function and the neural circuits that support impulsive behavior and the gratification mechanisms. Emotional experiences (stress, low level of education, divorce, poor social support) could constitute a possible risk factor that increases the GD. The committed offenses related to gambling could be explained by "loss of control". Conclusion. The results of the present study contributes to the body of knowledge regarding the size of phenomenon from a statistical and epidemiological point of view, suggesting the necessity for targeted information on the risks connected to GD in order to capture early warning signs which enables the intervention with suitable strategies.
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| 4. |
- Ferrara, R., et al.
(författare)
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Autism Spectrum Disorder and intact executive functioning
- 2016
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Ingår i: Clinica Terapeutica. - 0009-9074. ; 167:5, s. 96-101
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Earliest notions concerning autism (Autism Spectrum Disorders, ASD) describe the disturbance in executive functioning. Despite altered definition, executive functioning, expressed as higher cognitive skills required complex behaviors linked to the prefrontal cortex, are defective in autism. Specific difficulties in children presenting autism or verbal disabilities at executive functioning levels have been identified. Nevertheless, the developmental deficit of executive functioning in autism is highly diversified with huge individual variation and may even be absent. The aim of the present study to examine the current standing of intact executive functioning intact in ASD. Results: Analysis of ASD populations, whether high-functioning, Asperger's or autism Broad Phenotype, studied over a range of executive functions including response inhibition, planning, cognitive flexibility, cognitive inhibition, and alerting networks indicates an absence of damage/impairment compared to the typically-developed normal control subjects. Conclusions: These findings of intact executive functioning in ASD subjects provide a strong foundation on which to construct applications for growth environments and the rehabilitation of autistic subjects.
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| 5. |
- Ippoliti, F., et al.
(författare)
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Work-related Stress, over-nutrition and cognitive disability
- 2017
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Ingår i: Clinica Terapeutica. - 0009-9074. ; 168:1, s. 42-47
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Forskningsöversikt (refereegranskat)abstract
- Work-related stress may exert a negative impact on a variety of physical and psychological attributes relating to the health of employees and work organizations. Several studies conducted in Italy have shown that workers and employees who express less satisfaction show increased symptoms of obesity and cognitive disability. The latest evidence underlines the pathogenic relationship between stress and neurological disease through inflammatory neuro- immune activation. The aim of this review was to describe the relationship between workplace stress and adverse changes in lifestyle that develop into obesity, neuroinflammation and cognitive dysfunction. The molecular mechanisms involved and guidelines for the prevention of these trends are discussed briefly. © Società Editrice Universo (SEU).
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| 6. |
- Massoni, F., et al.
(författare)
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Psychopathology and neoplastic disease: Medico-social and medico-legal considerations
- 2017
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Ingår i: Clinica Terapeutica. - 0009-9074. ; 168:1, s. 48-53
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Forskningsöversikt (refereegranskat)abstract
- The cognitive disability associated with stress in patients presenting cancer disease may exert a significant impact on the psychological health of the individual and even deteriorate the clinical diagnosis. The present study consists of a review of the available literature and an analysis of the association between psychopathologic disease and cancer by selecting useful contributions to the medicosocial discussion of the topic. Interesting considerations have emerged on the epidemiology and pathogenesis of the association between psychopathology and cancer that initiated possibilities towards a greater accuracy in the assessment of the patient that is not only limited to oncologic problems and outcomes. © Società Editrice Universo (SEU).
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| 7. |
- Taffoni, F., et al.
(författare)
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Toys
- 2010
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Ingår i: Clinica Terapeutica. - 0009-9074. ; 161:6, s. 573-574
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Tidskriftsartikel (refereegranskat)abstract
- Toys denote objects used in playing. From the first examples of toys made of materials available in the environment and manufactured by parents or by children themselves only for recreational purpose, toys have evolved into more sophisticated devices which integrate mechanics, electronics and informatics (mechatronic toys) used in several different application fields. There are two main kinds of mechatronic toys: sensorized toys are passive toys equipped with a set of sensors used to record user-toy interactions; robotic toys are artefacts or computers, usually self-propelled with the help of motors, which collect information from the surrounding environment by sensors, and decode this information into behaviors consistent with them. This entry explores the use of the word "toys" from a technological point of view focussing on mechatronic toys and their applications.
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