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1.	Abraham, Maria Celina, et al. (författare) Semen collection methods in alpacas 2017 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 180, s. 613-614 Forskningsöversikt (refereegranskat)abstract South American camelids, particularly alpacas, are gaining in popularity outside their native lands. Reproductive biotechnologies, such as artificial insemination or embryo transfer with cryopreserved embryos, are more complicated in these species than many others due to differences in their reproductive physiology compared to the more commonly encountered domestic livestock. This article reviews the methods currently available for obtaining semen or spermatozoa from alpacas and describes some of the problems associated with handling the viscous seminal plasma characteristic of camelids. Possibilities and limitations of reproductive biotechnologies in this species are discussed, and future developments are outlined, especially some new techniques which are currently being developed for use with camel semen and may be transferable to alpacas.
2.	Andreen, Thomas, et al. (författare) Pain relief in dogs with hip dysplasia 2008 Ingår i: The Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 162:24, s. 796-796 Tidskriftsartikel (refereegranskat)
3.	Backhans, Annette, et al. (författare) Higher perceived risks of antimicrobial use are related to lower usage among pig farmers in four European countries 2016 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 179 Tidskriftsartikel (refereegranskat)abstract The prudent use of antimicrobials (AMs) should be widened in pig farming to reduce the risk of AM resistance (AMR) in human and veterinary medicine. It is therefore important to understand pig farmers' motivators and the barriers to AM usage (AMU) on their farms. The authors investigated pig farmers' self-estimated levels of AMU, their perceived benefits and risks and the need for AMs in a cross-sectional survey in Belgium, France, Germany and Sweden. The authors also compared these perceptions between the four countries and related them to pig farmers' actual AMU. The results showed that farmers who used more AMs also estimated their own usage as higher. Farmers perceived many benefits but relatively few risks of AMU in pig farming. Some significant cross-country differences in farmers' perceptions were found, but they were relatively small. After controlling for country differences and farm differences, only perceived risks had a significant association with AMU. The authors therefore conclude that in order to promote prudent AMU, it seems most promising to focus on the structural differences in pig farming and veterinary medicine (e.g. legislation, role of the veterinarian) among countries. In addition, interventions which aim at reducing AMU should increase farmers' awareness of the risks of extensive AMU.
4.	Backhans, Annette, et al. (författare) Profile of pig farms combining high performance and low antimicrobial usage within four European countries 2017 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 181 Tidskriftsartikel (refereegranskat)abstract Pig farmers are strongly encouraged to reduce their antimicrobial usage because of the rising threat from antimicrobial resistance. However, such efforts should not compromise the herd health status and performance. This study aimed to describe the profile of so-called 'top-farms' that managed to combine both high technical performance and low antimicrobial usage. A cross-sectional study was conducted among 227 farrow-to-finish farms in Belgium, France, Germany and Sweden. Among them, 44 farms were allocated to the top-farms group and were compared with the 'regular' farms group in terms of farm characteristics, biosecurity and health status. Top-farms had fewer gastrointestinal symptoms in suckling pigs and fewer respiratory symptoms in fatteners, which could partly explain their reduced need for antimicrobials and higher performance. They also had higher biosecurity and were located in sparsely populated pig areas. However, 14 farms of the top-farms group were located in densely populated pig areas, but still managed to have low usage and high technical performance; they had higher internal biosecurity and more extensive vaccination against respiratory pathogens. These results illustrate that it is possible to control infectious diseases using other approaches than high antimicrobial usage, even in farms with challenging environmental and health conditions.
5.	Bergström, Annika, et al. (författare) Long-term outcomes in dogs with elbow dysplasia, assessed using the canine orthopaedic index 2023 Ingår i: Veterinary Record. - 0042-4900 .- 2042-7670. ; 193 Tidskriftsartikel (refereegranskat)abstract BackgroundElbow dysplasia (ED) is an important cause of lameness in dogs. This study aimed to report long-term outcomes in dogs with elbow osteoarthritis. MethodsDemographic data, medical management, and scores from The American College of Veterinary Surgeons' Canine Orthopaedic Index (COI) were collected from owners of dogs radiographically screened for ED, graded as normal, mild, or moderate. Telephone interviews were performed in 2017 (Q1), followed by an email survey in 2020 (Q2). The association between ED grade and deterioration in COI scores over time was evaluated with logistic regression. ResultsA total of 765 replies were collected for Q1 and 293 for Q2. At Q2, 222 dogs (76%) were alive, with a median age of 8 years (range 5-12 years). No association was found between ED and changes in COI score over time or between ED and survival (p = 0.071). Dogs with mild and moderate ED were treated with analgesic medications to a higher degree than dogs without ED (p < 0.05). LimitationsOnly owner-assed data were assessed; no clinical orthopaedic examination or follow-up radiographic evaluation was performed. ConclusionsNo association was found between the grade of ED and the worsening of clinical signs in dogs with elbow osteoarthritis.
6.	Bergström, Annika (författare) Type and impact of clinical incidents identified by a voluntary reporting system covering 130 small animal practices in mainland Europe 2022 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 191 Tidskriftsartikel (refereegranskat)abstract Background Veterinary healthcare can be a complex process and may lead to unwanted, potentially harmful patient safety incidents as a consequence, negatively impacting both the practice team and client satisfaction. The aim of this study was to identify how such incidents impact cats and dogs by analysing reports gathered in a large-scale voluntary incident reporting system. Methods Descriptive statistical analysis was used to study a total of 2155 incident reports, submitted by 130 practices on mainland Europe. Results Incidents caused harm in more than 40% of reports. Medication-related incidents were the most frequent type of incident recorded (40%). Treatment-related incidents were the most common type of incident causing patient harm (55%). Anaesthesia-related incidents were the most severe type of incident, resulting in patient death in 18% of these reports. Most incidents were reported from hospital wards, and a significantly higher proportion of cats were harmed by incidents compared to dogs. Conclusion This study demonstrates that patients are regularly harmed by incidents, with medication-related incidents being most common. In depth understanding of incident data can help develop interventions to reduce the risk of incident recurrence.
7.	Bremer, Hanna, et al. (författare) Disease patterns and incidence of immune-mediated disease in insured Swedish Nova Scotia Duck Tolling Retrievers 2015 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 177 Tidskriftsartikel (refereegranskat)abstract In this study, morbidity in insured Nova Scotia Duck Tolling Retriever (NSDTR) dogs from Sweden was investigated and compared with all other breeds and other retriever breeds. In addition to describing common morbidities in NSDTRs, the hypotheses that NSDTRs are predisposed to lymphoma, immune-mediated rheumatic disease (IMRD) and steroid-responsive meningitis-arteritis (SRMA) were tested. Included in the study were 445,336 dogs; of which, 2890 were NSDTRs that had been covered by veterinary insurance from the Agria Insurance Company (Stockholm, Sweden) at some point during the years 1995-2006. Incidences of various health problems were calculated using the number of veterinary visits as the numerator and the exact time at risk as the denominator. Overall, morbidity was higher in NSDTRs compared with all other breeds, but similar compared with other retriever breeds. The most common causes of veterinary visits in NSDTRs were injuries, gastrointestinal disease and locomotor disorders, with NSDTRs at increased risk of these compared with all other breeds. The incidences for IMRD, SRMA and lymphoma were significantly higher in NSDTRs than in all other dog breeds and all other retriever breeds. The study describes morbidity in NSDTRs, and identifies several disorders to which the breed is predisposed.
8.	Egenvall, Agneta (författare) Designing studies to meet the task 2012 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 170, s. 561-562 Annan publikation (refereegranskat)
9.	Engdahl, Karolina, et al. (författare) Long-term outcome in dogs with cranial cruciate ligament disease evaluated using the canine orthopaedic index 2023 Ingår i: Veterinary Record. - 0042-4900 .- 2042-7670. ; 193 Tidskriftsartikel (refereegranskat)abstract BackgroundCranial cruciate ligament disease (CCLD) is common in dogs, but studies on the long-term treatment outcome are scarce. MethodsThe long-term outcome in a cohort of 71 dogs with CCLD treated with tibial plateau levelling osteotomy (TPLO, n = 18), tibial tuberosity advancement (TTA, n = 23) or lateral fabellotibial suture (LFS, n = 30) was evaluated using the canine orthopaedic index. ResultsThe risk of stiffness and lameness was increased in dogs treated with TPLO (stiffness: incidence rate ratio [IRR] 1.33, p = 0.015; lameness: IRR 1.34, p = 0.020) or TTA (stiffness: IRR 1.26, p = 0.035; lameness: IRR 1.31, p = 0.026) when compared to LFS at a median follow-up time of 4.6 years. LimitationsNo follow-up veterinary examination was performed. Data were collected from only two university animal hospitals, and thus, a referral bias towards more complicated cases is possible, which may limit the generalisability of the results. ConclusionClinicians can use the results to inform dog owners about the expected long-term outcome in dogs with CCLD.
10.	Engdahl, Karolina, et al. (författare) The epidemiology of stifle joint disease in an insured Swedish dog population 2021 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 189 Tidskriftsartikel (refereegranskat)abstract Background Stifle joint diseases (SJD) are common in dogs and include a variety of diagnoses. The objective of the study was to provide an overview of the epidemiology of SJD in insured dogs.Methods An historical single cohort study of dogs insured in Agria Pet Insurance (2011-2016) in Sweden was performed. Incidence and relative risk (RR) of SJD was calculated for the whole dog population and for subgroups divided by breed, breed group and sex.Results The study population included almost 600,000 insured dogs (>1.7 million dog-years). Ninety-three different stifle joint diagnoses were reported in 9624 dogs, and the most common were cruciate ligament rupture and patellar luxation. The incidence of SJD was 55.4 cases per 10,000 dog-years at risk. Bulldog and boerboel had the highest RR of SJD. The breeds that accounted for the highest proportion of all SJD claimed dogs were mixed breed and Labrador retriever. Female dogs had a slightly increased RR compared with male dogs (RR 1.06, p = 0.006). The incidence increased yearly during the observation period.Conclusion The study demonstrates breed-specific differences in incidence of SJD in dogs, which may be of importance for breeders, dog owners and veterinarians.
11.	Eriksson, E., et al. (författare) Verocytotoxin-producing Escherichia coli 0157:H7 in the Swedish pig population 2003 Ingår i: The Veterinary Record. - 0042-4900 .- 2042-7670. ; 152:23, s. 712-717 Tidskriftsartikel (refereegranskat)abstract Verocytotoxin-producing Escherichia coli O157:H7 (VTEC O157:H7) was detected in two of 2446 individual faecal samples collected from pigs slaughtered at five Swedish slaughterhouses, indicating a prevalence of 0.08 per cent, with a 95 per cent confidence interval from 0 to 0-16 per cent. Four Swedish VTEC O157:H7-positive farms which kept ruminants and pigs were studied by repeated faecal sampling; VTEC O157:H7 was isolated from the ruminants and pigs on all the farms and the same strains were present in the pigs and the ruminants. On one of the farms, the organism persisted in the pig population for 11 months. On all four farms, management practices which might have influenced the isolation rate in pigs were identified. A group of young VTEC O157:H7-positive pigs was moved from one of the VTEC O157:H7-positive farms to a fattening herd where there were no ruminants. The number of VTEC O157:H7-positive faecal samples decreased gradually and after nine weeks the pigs were all negative; at slaughter none of the pigs was VTEC O157:H7-positive.
12.	Eriksson, Helena, et al. (författare) Erysipelas in laying hens is associated with housing system 2013 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 173, s. 18- Tidskriftsartikel (refereegranskat)abstract Following the change from conventional cages to non-cage housing systems and furnished cages, which in Sweden was finalised by 2005, problems caused by Erysipelothrix rhusiopathiae increased in laying hen flocks. This study aimed to investigate possible associations between housing systems for laying hens and outbreaks of erysipelas. Also, sera from 129 flocks in different housing systems, collected during 2005-2007, were analysed for the presence of antibodies to E rhusiopathiae using an indirect ELISA test. Antibodies were detected in all housing systems. The mean flock absorbance values from free-range flocks were significantly higher than corresponding values from other housing systems. Data on the Swedish laying hen population were compared with the recorded number of erysipelas outbreaks during 1998-2011. Outbreaks occurred on 15 farms with indoor litter-based systems (n=194 farms in 2011) and on 21 free-range farms (n=87 farms in 2011). No outbreak was diagnosed on farms with flocks in conventional or furnished cages. The results indicate that the risk for an outbreak was higher in free-range systems than in indoor litter-based systems, and lowest for flocks housed in cages. Absence of erysipelas in the majority of subsequent flocks on the affected farms suggested that proper measures, including vaccination, were undertaken.
13.	Fahlman, Åsa (författare) Human exposures to immobilising agents: results of an online survey 2010 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 167, s. 327-332 Tidskriftsartikel (refereegranskat)abstract Cases of human exposure to veterinary injectable anaesthetics were reviewed following a literature search and completion of an online questionnaire in an attempt to provide an objective approach to the problem. The modified Glasgow Coma Scale was used to rank cases according to their severity. From the cases examined, results showed that intoxication with potent opioids, such as etorphine, carfentanil and thiafentanil, need to be treated with antagonists such as naloxone, nalmefene or naltrexone, and not with antagonists with agonistic properties, such as diprenorphine. With regard to the alpha(2)-agonists xylazine, detomidine, medetomidine and romifidine, no antagonist is currently accredited for human use. Atipamezole, a specific alpha(2)-antagonist, is widely used in veterinary medicine and has been used experimentally to reverse dexmetomidine in a study in human medicine. The high concentrations of alpha(2)-agonists being used in zoo and wildlife medicine warrant the accreditation of atipamezole for use in cases of human exposure. Knowledge and availability of the appropriate antagonist are essential in cases of human intoxication with injectable anaesthetics. Preventive measures, such as wearing gloves and eye protection, need to be used more regularly to reduce the risk of exposure.
14.	Fall, Tove, 1979-, et al. (författare) Glucagon stimulation test for estimating endogenous insulin secretion in dogs 2008 Ingår i: The Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 163:9, s. 266-270 Tidskriftsartikel (refereegranskat)abstract Fifty-one dogs (27 diabetic dogs, four that had recovered from diabetes and 20 healthy control dogs) were given 0.5 or 1.0 mg glucagon intravenously. Blood samples were taken before the injection and 10 and 20 minutes after it. Samples were analysed to determine C-peptide, insulin and glucose concentrations, and one sample from each dog was analysed for fructosamine. The median (interquartile range) concentrations of C-peptide in the samples taken at 10 minutes were 0.5 (0.3 to 0.8) nmol/l in the control dogs, 0.1 (0 to 0.2) nmol/l in the diabetic dogs, and 0.3 (0.2 to 0.4) nmol/l in the dogs that had recovered from diabetes. Seven of the 51 dogs showed mild adverse reactions after the injection of glucagon.
15.	Fernström, Lise-Lotte, et al. (författare) Presence of pathogenic bacteria in faeces from dogs fed raw meat-based diets or dry kibble 2020 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 187 Tidskriftsartikel (refereegranskat)abstract Background Feeding dogs with raw meat-based diets (RMBD) has increased in popularity in recent years. Proponents claim that RMBD is more natural for dogs, because it is what their ancestors (wolves) eat. Opponents claim that RMBD is a health hazard to both humans and animals, with a risk of spreading zoonotic bacteria and resistant bacterial strains.Methods This cross-sectional study investigated differences in bacteria shedding in faeces between dogs fed RMBD and dogs fed dry kibble. Faeces samples from 50 dogs from the same municipality were analysed for the presence of extended-spectrum beta-lactamases (ESBL)-producing Escherichia coli, Campylobacter and Salmonella.Results For the 25 dogs fed RMBD, ESBL E coli was isolated from 13 faeces samples, Campylobacter from 12 and Salmonella from 1. For the 25 dogs fed dry kibble, ESBL-producing E coli was isolated from one faeces sample and Campylobacter from four, while Salmonella was not detected.Conclusion There was thus a significant difference in excretion of zoonotic and resistant bacteria in faeces between dogs fed RMBD and dogs fed dry kibble. These results confirm that RMBD can pose a microbiological risk not only for dogs, but also for people handling RMBD and faeces from dogs.
16.	Frosth, Sara, et al. (författare) Ovine footrot: new insights into bacterial colonisation 2016 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 179 Tidskriftsartikel (refereegranskat)abstract Ovine footrot is characterised by interdigital dermatitis (ID) and by the separation of the skin and hoof horn (under-running footrot). Dichelobacter nodosus is the essential pathogen causing footrot; the role of other microorganisms in this disease remains unclear. The aims of this study were (i) to investigate the colonisation of D nodosus, Fusobacterium necrophorum and Treponema species in biopsies from the ovine interdigital skin of healthy, ID and footrot-affected feet and (ii) to characterise the virulence of D nodosus strains in those biopsies. Postslaughter biopsy samples (n= 241) were collected and analysed by real-time PCR to determine prevalence and load of the different bacterial species. The highest prevalence and load of D nodosus were found on feet with ID. The vast majority of samples contained virulent D nodosus and some samples contained both virulent and benign D nodosus. Notably, the more pathogenic subspecies of F necrophorum was found in samples from UK sheep. Our findings provide further insights into the role bacterial colonisation may play in the early stage of ID and in the progression towards footrot.
17.	Hagelin, Joakim, et al. (författare) Attitude of Swedish veterinary and medical students to animal experimentation 2000 Ingår i: The Veterinary Record. - 0042-4900 .- 2042-7670. ; 146:26, s. 757-760 Tidskriftsartikel (refereegranskat)abstract Nearly all veterinary and medical students (94 per cent) found it morally acceptable to use animals in research and believed it to be a necessity in order to treat human diseases. In contrast with the medical students a substantial proportion ofveterinary students (40 per cent) considered themselves animal rights activists. Unlike themedical curriculum, the veterinary curriculum contains a two-week course in laboratoryanimal medicine, and a higher proportion of the students who had not been through this course was opposed to the use of animals in research than of the students who had completed the course. The course modified the views of half the students; more than 26 per cent of them became more positive towards animal use in research after the courser whereas 3 per cent became more negative.
18.	Hamlin, Helene, et al. (författare) Steroid-responsive meningitis-arteritis in Nova Scotia duck tolling retrievers 2013 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 173 Tidskriftsartikel (refereegranskat)
19.	Hansson, Ingrid, et al. (författare) Detection of Campylobacter species in different types of samples from dairy farms 2020 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 186 Tidskriftsartikel (refereegranskat)abstract Background Livestock, domestic pets and wildlife can be intestinal carriers of thermotolerant Campylobacter species. These reservoirs can in turn contaminate the environment and food products, thus creating pathways to campylobacteriosis in human beings. The purposes of this study were to investigate sampling strategies applied for surveillance of Campylobacter on dairy cattle farms and to identify the presence and species of Campylobacter in different age groups.Methods Boot sock and faecal samples were collected from five dairy herds from three age groups-cows, heifers and calves younger than 12 months-and from milk filters.Results Campylobacter species were isolated in 152 of 250 samples, of which 93 isolates were identified as C jejuni, 51 as C hyointestinalis, two as C lari and one as C coli, whereas five isolates could not be identified to species level. Campylobacter species were isolated from 86 of 110 faecal samples, 60 of 97 sock samples and six of 43 milk filter samples.Conclusion Faecal samples were the optimal sample type for detection of Campylobacter on dairy farms. However, taking multiple types of samples could be recommended in order to optimise the recovery rate and variety of Campylobacter species detected when investigating the presence of Campylobacter on dairy farms.
20.	Hansson, Kerstin, et al. (författare) Comparison of macroscopic resorption time for a self-locking device and suture material in ovarian pedicle ligation in dogs 2019 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 184 Tidskriftsartikel (refereegranskat)abstract A resorbable self-locking device (LigaTie) was developed to enable safe and easy surgical ligation of blood vessels. The aim of this study was to compare the long-term in vivo resorption of the device to a commercially available suture of equivalent material (Maxon) following ovarian pedicle ligation. After ovariohysterectomy follow-up ultrasound examinations were performed monthly on 21 dogs ligated with the device and 22 dogs ligated with the suture material until no hyperechoic remnants, acoustic shadowing or local tissue reactions were detected. In both groups, the ovarian pedicles gradually decreased in size. Ligation material was considered macroscopically resorbed when ultrasound showed no signs of the device or suture, ovarian pedicle or tissue reaction. Macroscopic resorption had occurred without signs of complications and was complete by four months for sutures and 5.5 months for the device. The results show that resorption time in vivo for the resorbable self-locking device is mildly longer than suture of the same material and that no complications of device resorption were detected, supporting that the resorbable self-locking device is safe for in vivo use.
21.	Hellgren, Josefin, et al. (författare) Occurrence of Salmonella, Campylobacter, Clostridium and Enterobacteriaceae in raw meat-based diets for dogs 2019 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 184 Tidskriftsartikel (refereegranskat)abstract The practice of feeding raw meat-based diets (RMBD) to dogs has increased in popularity in recent years. However, RMBD are based on offal that has not undergone any type of treatment to reduce the microbial content, so there is a risk of potential pathogenic microorganisms being present. Frozen samples from 60 RMBD packs produced by 10 different manufacturers were analysed for their content of bacteria belonging to the family Enterobacteriaceae, for Clostridium perfringens and for the presence of Salmonella and Campylobacter. Enterobacteriaceae were detected in all 60 samples and in 31 samples exceeded a level of 5000 bacteria/g, which is the threshold for satisfactory microbial hygiene according to EU regulations. In two samples, the amount of C. perfringens exceeded 5000 bacteria/g, which is the maximum level of anaerobic bacteria permitted by Swedish national guidelines. Salmonella species were found in four (7 per cent) and Campylobacter species in three (5 per cent) samples. These results show that it is critical to maintain good hygiene when storing, handling and feeding RMBD, in order to limit the potential health risks to animals and humans, especially young and immunocompromised individuals.
22.	Hultin Jäderlund, Karin (författare) New aspects of hereditary ataxia in smooth-haired fox terriers 2010 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 166, s. 557-560 Tidskriftsartikel (refereegranskat)abstract Hereditary ataxia was diagnosed in three smooth-haired fox terrier puppies from Sweden, 25 years after the previous known case in the breed. In addition to the characteristic spinal cord pathology, brain involvement was evident clinically, in the form of behavioural changes and bilaterally decreased menace responses, and histopathologically, with degenerative changes in the brainstem. The striking similarities to hereditary ataxia in the jack Russell terrier suggest the same disease process in both breeds. A common ancestor, a female dog born in 1951 and considered a carrier of the disease at that time, was found in both the maternal and paternal lines of the three puppies.
23.	Humblot, Patrice, et al. (författare) Factors affecting the accuracy of pregnancy scanning in ewes 2013 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 173, s. 606- Tidskriftsartikel (refereegranskat)abstract The objective was to evaluate the accuracy of pregnancy scanning by transabdominal ultrasonography and affecting factors. Altogether 44,783 ewes were registered (2008-2010), 39,724 diagnosed as pregnant and subsequently lambed. The ewes, 0.5-14 years old, were divided into 4 age and 6 breed groups and analysed. The accuracy (per cent; number of scanned fetuses/number of born lambs) decreased with increasing number of fetuses (P<0.001). Overall accuracy was 90.3 per cent, highest (93.7 per cent) in ewes carrying one fetus, 91.9 per cent, 82.4 per cent, and 74.9 per cent in ewes with 2, 3 and >= 4 fetuses at scanning, respectively. Finnsheep ewes with highest number of lambs showed lowest accuracy (P<0.001). Analyses of a more complete sub set of data (n=23,396), showed that number of fetuses diagnosed, breed, age of ewe, operator and time in gestation, significantly affected the accuracy. Accuracy decreased with age of ewe (P<0.001) and was 71.8 per cent, 91.6 per cent and 89.3 per cent for scanning at <40, 40-80 and 81-100 days of gestation, respectively (P<0.001). In general, the numbers of fetuses were overestimated at scanning and increased gradually with number of fetuses diagnosed. In conclusion, the accuracy was affected by several factors, which should be considered when interpreting/implementing the results, especially in breeds with high fecundity.
24.	Hurri, Emma, et al. (författare) Post-thaw semen quality in young bull ejaculates before being accepted for commercial semen doses 2022 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 191 Tidskriftsartikel (refereegranskat)abstract Background: Genomic selection enables bulls with desirable characteristics to be identified at a young age, but sperm quality can be poor in the ejaculates of young bulls. Few studies have been done on post-thaw sperm quality in bulls less than 10 months old. The objective of this study was to determine the age at which post-thaw sperm quality was acceptable for artificial insemination.Methods: Semen was collected by artificial vagina; samples containing 100-500 million spermatozoa/ml were frozen for this study. Post-thaw analyses of membrane integrity (MI), mitochondrial membrane potential (MMP), chromatin integrity, morphology, production of reactive oxygen species and sperm kinematics were made.Results: The age at which ejaculates exceeded the breeding company's thresholds of acceptance varied considerably among individuals, with 285 days being the earliest. Morphology (p < 0.003), MI (p = 0.0096), high MMP (p = 0.043) and superoxide production (p = 0.0084) increased between the first and last ejaculates but reached acceptable levels at different ages for individual bulls.Conclusions: It was possible to obtain acceptable post-thaw sperm quality from samples even though sperm concentration was lower than the breeding company's threshold. Therefore, it might be feasible to use ejaculates earlier than is currently considered possible, by modifying semen handling protocols.
25.	Höglund, Johan, et al. (författare) Calving season is a stronger determinant of worm burdens in pasture-based beef production than the level of residual larval contamination at turnout 2013 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 172, s. 472- Tidskriftsartikel (refereegranskat)abstract The combined influence of (1) calving period (early or late) and (2) overwintering contamination by residual infective larvae (high or low) on subsequent exposure of suckler calves to gastrointestinal nematodes was investigated. We found that the effect of calving date was greater than the level of residual contamination. This was because the adult cows produced large quantities of manure containing small amounts of nematode eggs from turnout, which significantly contaminated the pasture, and thereby, reduced the effect of prior high-low contamination. Early born calves were found to be more heavily exposed to parasites, most likely due to ingesting more herbage than those born later. Late-born calves also had relatively high antibody levels at turnout, which first decreased and then increased again. We suggest that the high antibody levels at turnout reflect passive transfer of maternal antibodies through the milk. There was also a significant difference in animal performance, with the more heavily exposed early born calves having significantly lower daily weight gain than the late-born calves. However, this might not be entirely due to increased parasitism.
26.	Höglund, Johan (författare) Potential of diagnostic markers in sustainable control of cattle parasites 2011 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 169, s. 522-523 Annan publikation (refereegranskat)
27.	Höglund, Johan (författare) Practices to optimise gastrointestinal nematode control on sheep, goat and cattle farms in Europe using targeted (selective) treatments 2014 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 175, s. 250-255 Forskningsöversikt (refereegranskat)abstract Due to the development of anthelmintic resistance, there have been calls for more sustainable nematode control practices. Two important concepts were introduced to study and promote the sustainable use of anthelmintics: targeted treatments ( TT), where the whole flock/herd is treated based on knowledge of the risk, or parameters that quantify the severity of infection; and targeted selective treatments (TST), where only individual animals within the grazing group are treated. The aim of the TT and TST approaches is to effectively control nematode-induced production impacts while preserving anthelmintic efficacy by maintaining a pool of untreated parasites in refugia. Here, we provide an overview of recent studies that assess the use of TT/TST against gastrointestinal nematodes in ruminants and investigate the economic consequences, feasibility and knowledge gaps associated with TST. We conclude that TT/TST approaches are ready to be used and provide practical benefits today. However, a major shift in mentality will be required to make these approaches common practice in parasite control.
28.	Johansson, Karl-Erik (författare) VetBact - culturing bacteriological knowledge for veterinarians 2014 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 174, s. 162-164 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract In 2004, Karl-Erik Johansson, then professor of veterinary bacteriology at the veterinary school at Uppsala in Sweden, was asked by his students for a list of the most important bacteria and the diseases that they cause. So began the development of VetBact, an online database giving details of the bacterial species with most relevance to veterinary medicine. The non-commercial database, www.vetbact.org, has since grown and can now be accessed by veterinarians and others worldwide.
29.	Järhult, Josef D. (författare) One Health : a doctor's perspective 2015 Ingår i: The Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 176:14, s. 351-353 Tidskriftsartikel (refereegranskat)
30.	Karlstam, E., et al. (författare) Pulmonary artery lesions in cavalier King Charles spaniels 2000 Ingår i: The Veterinary Record. - 0042-4900 .- 2042-7670. ; 147:6, s. 166-167 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
31.	Lewerin, SS, et al. (författare) Outbreak of Mycobacterium tuberculosis infection among captive Asian elephants in a Swedish zoo 2005 Ingår i: The Veterinary record. - : Wiley. - 0042-4900 .- 2042-7670. ; 156:6, s. 171-175 Tidskriftsartikel (refereegranskat)
32.	Lilley, JH, et al. (författare) Pan-Asian spread of single fungal clone results in large scale fish kills 1997 Ingår i: The Veterinary Record. - 0042-4900 .- 2042-7670. ; 140:25, s. 653-654 Tidskriftsartikel (refereegranskat)
33.	Läikkö, Tina, et al. (författare) Canine tinsillitis associated with Listeria monocytogenes 2004 Ingår i: The Veterinary Record. - London, United Kingdom : British Veterinary Association. - 0042-4900 .- 2042-7670. ; 154:23, s. 732-732 Tidskriftsartikel (refereegranskat)
34.	Machado Tahamtani, Fernanda (författare) Post-mortem examination of fast-growing broilers with different degrees of identifiable gait defects 2021 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 189 Tidskriftsartikel (refereegranskat)abstract Background: The walking ability of many broilers is characterised by slight or definite defects categorised as gait scores (GS) 1 and 2. The present study aimed to examine potential relationships between GSs and indicators of body morphology, leg pathology, tibia strength and wooden breast in Ross 308 broilers assessed as GS <= 2.Methods: At 38 days of age, GS and live body weight of 179 birds was recorded. Each bird was examined post-mortem for signs of wooden breast, contact dermatitis and a range of leg pathologies. Weights of different body parts and tibia strength were quantified.Results: Within sex, GS increased with increasing live bodyweight (p = 0.020). There was a tendency for an effect of GS on prevalence of footpad dermatitis (p = 0.086) and dislocated femoral joint cartilage (p = 0.059) where both pathologies increased in frequency with increasing GS. Greater load was required to fracture tibia from GS2 than GS0 birds (p = 0.040).Conclusions: Within this relatively small data set, no strong relationships between GS = 2 and indicators of body morphology, leg pathology, tibia strength and wooden breast in Ross 308 broilers were found, except for the live terminal body weight. Further studies, involving larger data sets are required for full clarification.
35.	Mansa, S., et al. (författare) Long-term treatment with carprofen of 805 dogs with osteoarthritis 2007 Ingår i: The Veterinary Record. - 0042-4900 .- 2042-7670. ; 160:13, s. 427-430 Tidskriftsartikel (refereegranskat)abstract The pain-relieving effect of carprofen and tolerance to the drug were investigated in 805 dogs that were lame as a result of osteoarthritis. The dogs were of different breeds, ages and bodyweights and of both sexes, and were selected from 51 veterinary clinics. Each dog was treated orally by its owner with 4 mg/kg carprofen for 84 consecutive days. Twenty-four dogs were removed from the study because of side effects, and 55 left the study for reasons unrelated to the treatment. The condition of the dogs and the benefit of the treatment were evaluated by the veterinary surgeons and the owners after 14 days, and at the end of the period of treatment, when 194 of the dogs (26-7 per cent) were no longer lame, and 357 (49-2 per cent) had improved. The period for which the dogs had been lame before entering the study significantly (P < 0.01) affected the results and the rate of improvement. Too much exercise during the 84 days of treatment caused some dogs to relapse.
36.	Morrell, Jane (författare) Should single layer centrifugation of dog semen be done before or after the semen is cooled? 2015 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 176, s. 359- Tidskriftsartikel (refereegranskat)abstract The aim of this study was to assess the effectiveness of sperm selection by single layer centrifugation (SLC) on canine sperm quality when SLC was performed before or after the cooling process, or when double SLC (before and after cooling) was performed. Twenty ejaculates from four dogs were divided into four aliquots as follows: unselected: no SLC was performed; SLC prior to cooling (SLC-PC): sperm selection was carried out before cooling; SLC after cooling (SLC-AC): sperm selection was performed after cooling; and double SLC: sperm selection was carried out before and after cooling. Sperm motility (by computer-assisted semen analysis), morphology (Diff-Quick staining), sperm membrane integrity (Vital-Test kit) and acrosome integrity (double fluorescent stain) were assessed in re-warmed semen samples. Four sperm subpopulations (sP) were detected using a pattern analysis technique (sP1: highly active, non-progressive; sP2: low velocity, highly progressive; sP3: less vigorous, poorly progressive; sP4: highly progressive motility). A higher proportion of sperm were classified as sP4 in SLC-AC samples. Most of the sperm parameters assessed showed higher values in the SLC-AC group. We conclude that SLC-AC is the best protocol to improve sperm quality in chilled canine semen in comparison to the other procedures tested.
37.	Nordéus, Kristina, et al. (författare) Effects of pheromones on heart rate in bulls and heifers 2012 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 170, s. 496B- Tidskriftsartikel (refereegranskat)
38.	Ohlson, Anna, et al. (författare) Risk factors for seropositivity to bovine coronavirus and bovine respiratory syncytial virus in dairy herds 2010 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 167, s. 201-207 Tidskriftsartikel (refereegranskat)abstract A cross-sectional study was conducted to evaluate the association between herd-level characteristics, management routines and farm-level antibody status of bovine coronavirus (BCV) and bovine respiratory syncytial virus (BRSV) in 257 Swedish dairy herds. The possible spatial clustering of positive herds compared with negative herds was also investigated. For each herd, a pooled milk sample from five primiparous cows was analysed for the presence of antibodies to BCV and BRSV. Herd-level information was obtained by a questionnaire. Logistic regression was used to evaluate the association between predictors and antibody status to BCV and BRSV. Large herd size, being located in southern Sweden, and not providing boots for visitors were found to be associated with being antibody-positive to BCV and BRSV. A short distance to the nearest cattle herd was an additional risk factor for BCV. One of the studied areas was suitable for spatial analysis. Positive herds were not spatially autocorrelated when compared with negative herds as estimated by the K-function regarding both BCV and BRSV. This indicates that local factors such as daily visiting milk trucks and wild animals were unlikely to be important sources of infection in this area. Moran's / statistics and semi-variogram showed no evidence of spatial autocorrelation in the residuals, indicating that remaining unidentified factors are not spatially dependent in the areas under study.
39.	Ottinger, Therese, et al. (författare) Forensic veterinary pathology, today's situation and perspectives 2014 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 175 Tidskriftsartikel (refereegranskat)abstract To investigate the current status of forensic veterinary pathology, a survey was composed directed at pathology laboratories and institutes, mostly in Europe. The questions included number of and type of cases, resources available, level of special training of the investigating pathologists and the general view on the current status and future of the discipline. The surveys were sent to 134 laboratories and were returned by 72 respondents of which 93 per cent work on forensic pathology cases. The results indicate scarcity of training opportunities and special education, and insufficient veterinary-specific reference data and information on forensic analyses. More cooperation with human forensic pathology was desired by many respondents, as was more interaction across country borders.
40.	Pelander, Lena, et al. (författare) Incidence of and mortality from kidney disease in over 600,000 insured Swedish dogs 2015 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 176, s. 656- Tidskriftsartikel (refereegranskat)abstract Kidney disease is an important cause of morbidity and mortality in dogs. Knowledge about the epidemiology of kidney disease in the dog population is valuable and large-scale epidemiological studies are needed. The aim of the present study was to use insurance data to estimate kidney-related morbidity and mortality in the Swedish dog population. Insurance company data from insured dogs during the years 1995-2006 were studied retrospectively. Incidence and mortality were calculated for the whole group of dogs as well as divided by sex and breed. The total number of veterinary care insured dogs was 665,245. The total incidence of kidney disease in this group of dogs was 15.8 (15.3-16.2) cases/10,000 dog-years at risk. The number of dogs in the life insurance was 548,346 and in this group the total kidney-related mortality was 9.7 (9.3-10.2) deaths/10,000 dog-years at risk. The three breeds with the highest incidence of kidney disease were the Bernese mountain dog, miniature schnauzer and boxer. The three breeds with the highest mortality caused by kidney disease were the Bernese mountain dog, Shetland sheepdog and flat-coated retriever. In conclusion, the epidemiological information provided in this study concerning kidney disease in dogs can provide valuable information for future research.
41.	Pelander, Lena, et al. (författare) Myocardial cell damage in 24 dogs bitten by the common European viper (Vipera berus) 2010 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 166, s. 687-690 Tidskriftsartikel (refereegranskat)abstract This study investigated whether myocardial damage, as reflected by increased serum concentrations of cardiac-specific troponin I (cTnI), develops in dogs as a result of a bite from a common European viper (Vipera berus), and whether this damage occurs in the absence of clinically relevant ECG abnormalities. Twenty-four dogs presented following a snake bite were tested. On admission, and after 12, 24 and 36 hours, an ECG was recorded and serum was collected for analysis of cTnI from all the dogs. Thirteen dogs (54 per cent) had an undetectable serum cTnI concentration (<0.2 mu g/l) and no abnormalities on ECG, five dogs (21 per cent) had increased serum concentrations of cTnI and no ECG abnormalities, six dogs (12.5 per cent) had increased cTnI concentrations and ECG abnormalities, and six dogs (12.5 per cent) had ECG abnormalities and undetectable cTnI concentrations. Only three dogs (12.5 per cent) had serum cTnI concentrations exceeding 1.0 mu g/l at any time during the study. Evidence of myocardial cell damage was found in eight (32 per cent) of the 24 dogs. Cardiac arrhythmia was detected in three of these eight dogs.
42.	Penell, Johanna (författare) Evidence of longer life; a cohort of 39 labrador retrievers 2018 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 182 Tidskriftsartikel (refereegranskat)abstract A panel of veterinary and academic experts reviewed current available evidence on age at death for labradors and reached a consensus that their average/typical life span was 12years of age.1 A prospective cohort study that described the longevity of 39 pedigree adult neutered labradors, showed that 89.7 per cent lived to meet/exceed this typical life span. The study showed that maintenance of lean body mass and reduced accumulation of body fat were associated with attaining a longer than average life span while sex and age at neutering were not associated with longevity.
43.	Persson Waller, Karin (författare) Selective approach to dry cow therapy 2019 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 184, s. 29-30 Tidskriftsartikel (refereegranskat)
44.	Persson Waller, Karin, et al. (författare) Veterinary treatment strategies for clinical mastitis in dairy cows in Sweden 2016 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 178 Tidskriftsartikel (refereegranskat)abstract To evaluate if Swedish veterinary guidelines on use of antimicrobials in cases of clinical mastitis in dairy cows have been adopted by veterinary practitioners, their treatment strategies were evaluated in a cross-sectional study using a web-based questionnaire. Another aim was to study if the strategies differed among veterinarians due to year and country of exam, sex, region, numbers of mastitis cases per month, and postgraduate training in herd health using multivariable logistic regression models. In total, 267 of 741 (36 per cent) veterinarians contacted answered the questionnaire satisfactorily. Most considered bacteriological diagnostics important, but many veterinarians made treatment decisions without collecting information on antimicrobial susceptibility. Moreover, few veterinarians used measuring tape to assess bodyweight before dosing parenteral antimicrobials. Year of exam and postgraduate training were the veterinary demographic factors associated with most treatment routines. The questions associated with most demographic factors were if antimicrobial treatment is affected by knowledge on earlier udder pathogens in the herd, and how often NSAID and follow-up of treatment using milk somatic cell count are used. Overall, the veterinarians followed the Swedish guidelines rather well, but discrepancies in need for improvement were found.
45.	Rohdin, Cecilia, et al. (författare) Assessment of glial fibrillary acidic protein and anti-glial fibrillary acidic protein autoantibody concentrations and necrotising meningoencephalitis risk genotype in dogs with pug dog myelopathy 2024 Ingår i: Veterinary Record. - 0042-4900 .- 2042-7670. ; 194 Tidskriftsartikel (refereegranskat)abstract BackgroundPugs commonly present with thoracolumbar myelopathy, also known as pug dog myelopathy (PDM), which is clinically characterised by progressive signs involving the pelvic limbs, no apparent signs of pain and, often, incontinence. In addition to meningeal fibrosis and focal spinal cord destruction, histopathology has confirmed lymphohistiocytic infiltrates in the central nervous system (CNS) in a considerable number of pugs with PDM. Lymphohistiocytic CNS inflammation also characterises necrotising meningoencephalitis (NME) in pugs. This study aimed to investigate the potential contribution of an immunological aetiology to the development of PDM.MethodsThe concentrations of glial fibrillary acidic protein (GFAP) in serum and CSF and of anti-GFAP autoantibodies in CSF were measured with an ELISA. In addition, a commercial test was used for genetic characterisation of the dog leukocyte antigen class II haplotype, which is associated with NME susceptibility.ResultsThis study included 87 dogs: 52 PDM pugs, 14 control pugs, four NME pugs and 17 dogs of breeds other than pugs that were investigated for neurological disease (neuro controls). Anti-GFAP autoantibodies were present in 15 of 19 (79%) of the PDM pugs tested versus six of 16 (38%) of the neuro controls tested (p = 0.018). All 18 PDM pugs evaluated had detectable CSF GFAP. Serum GFAP was detected in two of three (67%) of the NME pugs and in two of 11 (18%) of the control pugs but not in any of the 40 tested PDM pugs. Male pugs heterozygous for the NME risk haplotype had an earlier onset of clinical signs (70 months) compared to male pugs without the risk haplotype (78 months) (p = 0.036).LimitationsThe study was limited by the lack of healthy dogs of breeds other than pugs and the small numbers of control pugs and pugs with NME.ConclusionsThe high proportion of PDM pugs with anti-GFAP autoantibodies and high CSF GFAP concentrations provide support for a potential immunological contribution to the development of PDM.
46.	Rohdin, Cecilia, et al. (författare) High prevalence of gait abnormalities in pugs 2018 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 182, s. 1-9 Tidskriftsartikel (refereegranskat)abstract The objective of this prospective study was to determine the prevalence of gait abnormalities in a cohort of Swedish pugs by using an owner-based questionnaire targeting signs of gait abnormality and video footage showing the dog's gait. This study also evaluated associated conditions of abnormal gait, including other health disorders prevalent in the breed. Five hundred and fifty (550) pugs registered in the Swedish Kennel Club, of one, five and eight years of age, in 2015 and 2016, were included in the study. Gait abnormalities were reported in 30.7 per cent of the responses. In the majority of cases, the character of the described gait indicated a neurological cause for the gait abnormality. An association was observed between abnormal gait and age, with gait abnormalities being significantly more common in older pugs (P=0.004). An association was also found between abnormal gait and dyspnoea, with dyspnoea being significantly more common in pugs with gait abnormalities (P<0.0001). This study demonstrated that the prevalence of gait abnormalities was high in the Swedish pug breed and increased with age. Future studies on the mechanisms behind these gait abnormalities are warranted.
47.	Sabés-Alsina, Maria, et al. (författare) Effects of season on bull sperm quality in thawed samples in northern Spain 2017 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 180, s. 251- Tidskriftsartikel (refereegranskat)abstract The aim of the present study was to evaluate the possible effects of climate factors on sperm quality of Holstein dairy bulls housed in northern Spain. Semen samples from 11 Holstein dairy bulls were collected and cryopreserved in winter, spring and summer. Sperm quality parameters such as motility, morphology, plasma membrane integrity, acrosome status, mitochondrial membrane potential, DNA fragmentation index and reactive oxygen species were assessed. Samples collected in spring showed higher mean values of total and progressive motility compared with samples collected in winter. Mean values of average path velocity and straight-line velocity were higher in spring than in summer. The proportion of viable spermatozoa was higher in spring than in winter as was the proportion of viable spermatozoa with non-reacted acrosome. The proportion of live cells that were not producing superoxide or hydrogen peroxide was higher in samples collected in spring than in winter. No differences were found in sperm morphology or the DNA fragmentation index among seasons. In conclusion, results suggest that sperm quality of bulls housed in northern Spain is affected by season. Samples collected in spring appear to have better sperm quality than samples collected in other seasons.
48.	Sjölund, Marie, et al. (författare) Effects of different antimicrobial treatments on serum acute phase responses and leucocyte counts in pigs after a primary and a secondary challenge infection with Actinobacillus pleuropneumoniae 2011 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 169 Tidskriftsartikel (refereegranskat)abstract The susceptibility to an initial challenge and a re-challenge inoculation with Actinobacillus pleuropneumoniae was analysed in pigs that were treated with antimicrobials of different efficacies following the first exposure to A pleuropneumoniae. In brief, 30 nine-week-old specific pathogen-free pigs were allocated to five groups of six. After acclimatisation, four groups were inoculated with A pleuropneumoniae serotype 2. At the onset of clinical signs, three of the groups of pigs were treated with enrofloxacin, tetracycline or penicillin. A fourth group served as the inoculated control and the fifth group as a control group that had not been inoculated. On day 28, all five groups were re-challenged with the same strain of A pleuropneumoniae serotype 2 as had been used in the first inoculation. No treatments were carried out at this time. The acute phase responses and differential leucocyte counts were monitored in detail after both inoculations. Leucocytosis and acute phase responses in the forms of serum amyloid A, pig-major acute phase protein and haptoglobin were recorded in all of the inoculated groups after the onset of clinical signs following the first inoculation. A porcine mannan-binding lectin-A response was less evident in the pigs. Acute phase responses resembling those of the first inoculation were observed in the pigs that had not previously been inoculated and in the pigs treated with enrofloxacin. Acute phase responses were not recorded in the other three groups, where the pigs had seroconverted to A pleuropneumoniae serotype 2 following the first inoculation.
49.	Sjölund, Marie, et al. (författare) Responses of pigs to a re-challenge with Actinobacillus pleuropneumoniae after being treated with different antimicrobials following their initial exposure 2009 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 164, s. 550-555 Tidskriftsartikel (refereegranskat)
50.	Stadig, Sarah, et al. (författare) Evaluation and comparison of pain questionnaires for clinical screening of osteoarthritis in cats 2019 Ingår i: Veterinary Record. - : Wiley. - 0042-4900 .- 2042-7670. ; 185 Tidskriftsartikel (refereegranskat)abstract Background Feline osteoarthritis (OA) is a common cause of long-standing pain and physical dysfunction. Performing a physical examination of a cat is often challenging. There is a need for disease-specific questionnaires or the so-called clinical metrology instruments (CMIs) to facilitate diagnosis and evaluation of treatment of feline OA. The CMI provides the owners an assessment of the cat's behavioural and lifestyle changes in the home environment. The purpose of the study was to evaluate readability, internal consistency, reliability and discriminatory ability of four CMIs.Methods This is a prospective, cross-sectional study with 142 client-owned cats. Feline OA was diagnosed based on medical history, orthopaedic examination and radiography.Results The results indicate that all four instruments have sound readability, internal consistency, are reliable over time and have good discriminatory ability. Preliminary cut-off values with optimal sensitivity and specificity were suggested for each instrument. The osteoarthritic cats showed significant changes in behavioural response to pain during orthopaedic examination, compared with sound cats.Conclusion The results indicate that all four questionnaires make an important contribution in a clinical setting, and that the cat's behavioural response to pain during physical examination should be a parameter to take into account as a possible indication of chronic pain.

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