| 1. |
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| 2. |
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| 3. |
- Arendt Nielsen, Lars, et al.
(författare)
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Pathophysiological mechanisms in chronic musculoskeletal pain (fibromyalgia) : the role of central and peripheral sensitization and pain disinhibition
- 2007
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Ingår i: Baillière's Best Practice & Research. - : Elsevier BV. - 1521-6942 .- 1532-1770. ; 21:3, s. 465-480
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Tidskriftsartikel (refereegranskat)abstract
- Chronic musculoskeletal pain has biological, psychological and social components. This review deals with the biological factors, with emphasis on the fibromyalgia syndrome (FMS). Studies on central sensitization of pain-transmitting neurons, changes in endogenous pain modulation that give rise to pain disinhibition, referred pain, pain-related decrease in muscle strength and endurance, and pain generators in deep tissues are reviewed. In FMS there is strong scientific support for the statement that the biological part of the syndrome is a longstanding or permanent change in the function of the nociceptive nervous system that can be equated with a disease. Further research is necessary in order to determine which methods are best for diagnosis of the pain hypersensitivity in clinical practice. FMS may be the far end of a continuum that starts with chronic localized/regional musculoskeletal pain and ends with widespread chronic disabling pain. © 2007 Elsevier Ltd. All rights reserved.
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| 4. |
- Axen, I, et al.
(författare)
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Trajectories of low back pain
- 2013
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Ingår i: Best practice & research. Clinical rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 27:5, s. 601-612
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Tidskriftsartikel (refereegranskat)
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| 5. |
- Barturen, G, et al.
(författare)
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SLE redefined on the basis of molecular pathways
- 2017
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Ingår i: Best practice & research. Clinical rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 31:3, s. 291-305
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Tidskriftsartikel (refereegranskat)
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| 6. |
- Bengtsson, Anders A., et al.
(författare)
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Role of interferons in SLE
- 2017
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Ingår i: Baillière's Best Practice & Research. - : Elsevier BV. - 1521-6942 .- 1532-1770. ; 31:3, s. 415-428
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Tidskriftsartikel (refereegranskat)abstract
- Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease that affects many different organ systems, with excessive production of type I interferons (IFNs) and auto antibodies against nucleic acids as hallmarks. Activation of the type I IFN system in SLE is due to continuous stimulation of plasmacytoid dendritic cells by endogenous nucleic acids, leading to sustained type I IFN production. This is reflected by an over expression of type I IFN-regulated genes or an IFN signature. Type I IFNs have effects on both the innate and adaptive immune systems, which contribute to both loss of tolerance and the autoimmune disease process. In this review, we discuss the current understanding of IFNs in SLE, focusing on their regulation, the influence of genetic background, and environmental factors and therapies that are under development aiming to inhibit the type I IFN system in SLE.
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| 7. |
- Bergman, Stefan, 1959-
(författare)
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Management of musculoskeletal pain
- 2007
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Ingår i: Baillière's Best Practice & Research. - Oxford : Bailliere Tindall. - 1521-6942 .- 1532-1770. ; 21:1, s. 153-166
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Tidskriftsartikel (refereegranskat)abstract
- Chronic musculoskeletal pain is a major public health problem affecting about one third of the adult population. Pain is often present without any specific findings in the musculoskeletal system and a strictly biomedical approach could be inadequate. A biopsychosocial model could give a better understanding of symptoms and new targets for management. Identification of risk factors for chronicity is important for prevention and early intervention. The cornerstones in management of chronic non-specific, and often widespread, musculoskeletal pain are non-pharmacological. Physical exercise and cognitive behavioral therapy, ideally in combination, are first line treatments in e.g. chronic low back pain and fibromyalgia. Analgesics are useful when there is a specific nociceptive component, but are often of limited usefulness in non-specific or chronic widespread pain (including fibromyalgia). Antidepressants and anticonvulsants could be of value in some patients but there is a need for more knowledge in order to give general recommendations.
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| 8. |
- Bergman, Stefan, 1959-
(författare)
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Public health perspective - how to improve the musculoskeletal health of the population
- 2007
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Ingår i: Baillière's Best Practice & Research. - Oxford : Bailliere Tindall. - 1521-6942 .- 1532-1770. ; 21:1, s. 191-204
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Tidskriftsartikel (refereegranskat)abstract
- Musculoskeletal disorders are the most common cause of long-term sick leave in several western countries and individuals with chronic musculoskeletal pain score very low on health status measurements. Musculoskeletal health is multidimensional and is best understood from a biopsychosocial perspective. Body structure and function interacts with personal and environmental factors, affecting the ability to perform activities and participate in society. Interventions aimed at the whole population must attend to the underlying causes of musculoskeletal disorders and promote a healthy lifestyle. Safe environments and activities could reduce the risk of traumatic events and also make participation possible for those with a disability. Public beliefs about musculoskeletal symptoms and consequences need to be changed in order to minimise fear and avoidance, which, together with other psychosocial factors, could lead to chronicity. Public awareness and identification of those at risk for the development of musculoskeletal problems could lead to early and properly timed management.
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| 9. |
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| 10. |
- Bremander, Ann, et al.
(författare)
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Non-pharmacological management of musculoskeletal disease in primary care
- 2008
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Ingår i: Baillière's Best Practice & Research. - : Elsevier BV. - 1521-6942 .- 1532-1770. ; 22:3, s. 563-77
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Tidskriftsartikel (refereegranskat)abstract
- Musculoskeletal diseases as a group are one of the most common causes of contact in primary care and the most common causes of disability and long-term sick leave in several Western countries. Pain and dysfunction are often present without any specific findings in the musculoskeletal system, and a strictly biomedical approach is often inadequate. Body structure and function interact with personal and environmental factors, affecting the ability to perform activities and participate in society. It is important to meet these needs in primary care, and non-pharmacological principles such as physical activity and patient education with a cognitive approach are cornerstones in a multimodal management model.
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| 11. |
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| 12. |
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| 13. |
- Ebeling, P, et al.
(författare)
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Role of biochemical markers in the management of osteoporosis
- 2001
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Ingår i: Best Practice & Research: Clinical Rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 15:3, s. 385-400
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Tidskriftsartikel (refereegranskat)abstract
- Several serum and urine biochemical markers of bone resorption and formation have been developed. Biochemical bone markers have been used as intermediate end-points in all major studies of anti-osteoporotic therapies. Bone resorption markers, in particular, may add an independent, predictive value to the assessment of bone loss and fracture risk. There are also potential advantages in monitoring anti-osteoporotic treatment in the short-term in addition to bone densitometry, to rapidly identify non-responders to therapy, or non-compliance. Despite these recent advances, until now bone markers have simply been very useful research tools, with their clinical utility being limited by intra-individual and diurnal variability. However, the probability of the true bone mineral density response to hormone replacement therapy for the individual patient may be predicted using algorithms based on a spectrum of cut-off bone marker levels with varying false positive and negative rates. Thus, the transition of biochemical bone markers into everyday clinical practice may be rapidly approaching.
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| 14. |
- Englund, Martin
(författare)
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The role of biomechanics in the initiation and progression of OA of the knee.
- 2010
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Ingår i: Best Practice & Research: Clinical Rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 24:1, s. 39-46
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Tidskriftsartikel (refereegranskat)abstract
- The knee is one of the most common joints affected by osteoarthritis (OA), frequently with clinical presentation by middle age or even earlier. Accumulating evidence supports that knee OA progression is often driven by biomechanical forces, and the pathological response of tissues to such forces leads to structural joint deterioration, knee symptoms and reduced function. Well-known biomechanical risk factors for progression include joint malalignment and meniscal tear. The high risk of OA after knee injury demonstrates the critical role of biomechanical factors also in incident disease in susceptible individuals. However, our knowledge of the contributing biomechanical mechanisms in the development of early disease and their order of significance is limited. Part of the problem is our current lack of understanding of early-stage OA, when it starts and how to define it.
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| 15. |
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| 16. |
- Galindo-Feria, AS, et al.
(författare)
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Autoantibodies: Pathogenic or epiphenomenon
- 2022
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Ingår i: Best practice & research. Clinical rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 36:2, s. 101767-
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Tidskriftsartikel (refereegranskat)
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| 17. |
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| 18. |
- Haldeman, Scott, et al.
(författare)
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Advancements in the Management of Spine Disorders
- 2012
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Ingår i: Best Practice & Research: Clinical Rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 26:2, s. 263-280
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Tidskriftsartikel (refereegranskat)abstract
- Spinal disorders and especially back and neck pain affect more people and have greater impact on work capacity and health-care costs than any other musculoskeletal condition. One of the difficulties in reducing the burden of spinal disorders is the wide and heterogeneous range of specific diseases and non-specific musculoskeletal disorders that can involve the spinal column, most of which manifest as pain. Despite, or perhaps because of its impact, spinal disorders remain one of the most controversial and difficult conditions for clinicians, patients and policymakers to manage. This paper provides a brief summary of advances in the understanding of back and neck pain over the past decade as evidenced in the current literature. This paper includes the following sections: a classification of spinal disorders; the epidemiology of spine pain in the developed and developing world; key advancements in biological and biomechanical sciences in spine pain; the current status of potential methods for the prevention of back and neck pain; rheumatological and systemic disorders that impact the spine; and evidence-based surgical and non-surgical management of spine pain. The final section of this paper looks to the future and proposes actions and strategies that may be considered by the international Bone and Joint Decade (BJD), by providers, institutions and by policymakers so that we may better address the burden of spine disorders at global and local levels. (C) 2012 Elsevier Ltd. All rights reserved.
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| 19. |
- Heinegård, Dick, et al.
(författare)
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Preface.
- 2011
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Ingår i: Best Practice & Research: Clinical Rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 25:6, s. 749-750
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Tidskriftsartikel (refereegranskat)
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| 20. |
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| 21. |
- Järvinen, Tero A. H., et al.
(författare)
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Muscle injuries : optimising recovery
- 2007
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Ingår i: Baillière's Best Practice & Research. - : Elsevier BV. - 1521-6942 .- 1532-1770. ; 21:2, s. 317-331
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Tidskriftsartikel (refereegranskat)abstract
- Muscle injuries are one of the most common traumas occurring in sports. Despite their clinical importance, there are only a few clinical studies on the treatment of muscle injuries. Lack of clinical studies is most probably attributable to the fact that there is not only a high heterogeneity in the severity of injuries, but also the injuries take place in different muscles, making it very demanding to carry out clinical trials. Accordingly, the current treatment principles of muscle injuries have either been derived from experimental studies or been tested empirically only. Clinically, first aid for muscle injuries follows the RICE (Rest, Ice, Compression and Elevation) principle. The objective of RICE is to stop the injury-induced bleeding into the muscle tissue and thereby minimise the extent of the injury. Clinical examination should be carried out immediately after the injury and 5-7 days after the initial trauma, at which point the severity of the injury can be assessed more reliably. At that time, a more detailed characterisation of the injury can be made using imaging diagnostic modalities (ultrasound or MRI) if desired. The treatment of injured skeletal muscle should be carried out by immediate immobilisation of the injured muscle (clinically, relative immobility/avoidance of muscle contractions). However, the duration of immobilisation should be limited to a period sufficient to produce a scar of sufficient strength to bear the forces induced by remobilisation without re-rupture and the return to activity (mobilisation) should then be started gradually within the limits of pain. Early return to activity is needed to optimise the regeneration of healing muscle and recovery of the flexibility and strength of the injured skeletal muscle to pre-injury levels. The rehabilitation programme should be built around progressive agility and trunk stabilisation exercises, as these exercises seem to yield better outcome for injured skeletal muscle than programmes based exclusively on stretching and strengthening of the injured muscle.
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| 22. |
- Kanis, J A, et al.
(författare)
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How to decide who to treat
- 2009
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Ingår i: Best practice & research. Clinical rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 23:6, s. 711-26
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Tidskriftsartikel (refereegranskat)abstract
- Fractures are the clinical consequence of osteoporosis and are a major cause of morbidity and mortality worldwide. Although treatments are available that have been shown to decrease the risk of fracture, problems arise in identifying individuals at high risk of fracture so that intervention can be effectively targeted. Practice guidelines, available in many countries, differ markedly in approach, but generally recommend treatments on the basis of a previous fragility fracture and a defined threshold for bone mineral density (BMD). Recent developments in fracture risk assessment include the availability of the FRAX tool by the World Health Organization (WHO) Collaborating Centre for Metabolic Bone Diseases at Sheffield, UK, that integrates the weight of clinical risk factors for fracture risk with or without information on BMD and computes the 10-year probability of fracture. The tool increases sensitivity without trading specificity and is now being used in the re-appraisal of clinical guidelines.
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| 23. |
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| 24. |
- Larsson, Britt, 1953-, et al.
(författare)
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Work related neck-shoulder pain : a review on magnitude, risk factors, biochemical characteristics, clinical picture and preventive interventions
- 2007
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Ingår i: Baillière's Best Practice & Research. - : Elsevier BV. - 1521-6942 .- 1532-1770. ; 21:3, s. 447-463
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Tidskriftsartikel (refereegranskat)abstract
- The purpose of this review is to scrutinize the physiology of neck-shoulder pain and trapezius myalgia based on the most recent scientific literature. Therefore, systematic literature searches have been conducted. Occurrence of neck-shoulder pain, risk factors for development of neck-shoulder pain, and its work-relatedness are addressed. Furthermore, the latest information on the biochemical milieu within healthy and painful neck-shoulder muscles is reviewed. Finally diagnosis of and intervention for neck and shoulder pain are discussed. © 2007 Elsevier Ltd. All rights reserved.
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| 25. |
- Lidgren, Lars
(författare)
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Looking back at the start of the bone and joint decade what have we learnt?
- 2012
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Ingår i: Best Practice & Research: Clinical Rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 26:2, s. 169-171
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Tidskriftsartikel (refereegranskat)abstract
- The Bone and Joint Decade 2000-2010 started as a Swedish initiative in 1996 leading to the UN declaration 1999 followed by the WHO launch 2000. A ten year multidisciplinary and global endeavor moving musculoskeletal conditions onto the research and health agenda is now recognized. Some lessons learned during the journey are presented.
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| 26. |
- Mahr, Alfred, et al.
(författare)
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ANCA-associated vasculitis and malignancy: Current evidence for cause and consequence relationships
- 2013
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Ingår i: Best Practice & Research: Clinical Rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 27:1, s. 45-56
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Tidskriftsartikel (refereegranskat)abstract
- In this review, we summarise the current understanding of the potential link between cancer and anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), including granulomatosis with polyangiitis (Wegener's; GPA) and microscopic polyangiitis (MPA). As is true for many autoimmune or inflammatory rheumatic diseases, AAV diagnosis and therapy are associated with an increased risk of de novo cancer development, likely as a result of impaired immunosurveillance, direct oncogenicity of immunosuppressive agents and perhaps malignant degeneration of tissues undergoing chronic immune stimulation. Data from several studies suggest a standardised incidence ratio of cancer in AAV of 1.6-2.0 compared to the general population and a possibly higher risk in GPA than in MPA. The most prominent cancers observed in AAV include urinary tract cancer, leukaemia and non-melanoma skin cancer. The effect of individual therapeutic agents is difficult to dissect, but cyclophosphamide has emerged as a major contributor to cancer development because of its direct carcinogenic properties. Awareness of cancer risk in AAV calls for increased implementation of measures to prevent or screen for cancer and development of less carcinogenic therapies. Cancer has also been suggested as a potential trigger or cause of AAV. Although some studies found that prior or concomitant history of cancer increases the risk of AAV, available data are inconsistent and suggest that the fraction of AAV that might be attributable to cancer is at best small. (C) 2012 Elsevier Ltd. All rights reserved.
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| 27. |
- Mann, HF, et al.
(författare)
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Treatment-resistant inflammatory myopathy
- 2010
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Ingår i: Best practice & research. Clinical rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 24:3, s. 427-440
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Tidskriftsartikel (refereegranskat)
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| 28. |
- Mannerkorpi, Kaisa, 1955, et al.
(författare)
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Non-pharmacological treatment of chronic widespread musculoskeletal pain
- 2007
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Ingår i: Baillière's Best Practice & Research. - : Elsevier BV. - 1521-6942 .- 1532-1770. ; 21, s. 513-34
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Forskningsöversikt (refereegranskat)abstract
- Non-pharmacological treatment for patients with chronic widespread pain (CWP) and fibromyalgia (FM) aims to enhance overall health. This chapter reviews studies of exercise, education, movement therapies and sensory stimulation. Based on a systematic review of randomized controlled trials (RCTs), we suggest that aerobic exercise of low to moderate intensity, such as walking and pool exercise, can improve symptoms and distress in patients with CWP and FM, and it may improve physical capacity in sedentary patients. Aerobic exercise of moderate to high intensity has been shown to improve aerobic capacity and tender-point status. Educational programmes have been shown to enhance self-efficacy and health perception. There is no conclusive evidence about the type of educational programme that works best, but a small-group format and interactive discussions appear to be important components. Exercise combined with education appears to produce synergies. Studies of movement therapies (such as qigong) and sensory treatments (such as acupuncture and massage) are few in number. There is today no conclusive evidence about the effects of these treatments in CWP, although positive effects have been reported in a few studies. © 2007 Elsevier Ltd. All rights reserved.
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| 29. |
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| 30. |
- Parodis, Ioannis, 1981-, et al.
(författare)
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Reframing health disparities in SLE : A critical reassessment of racial and ethnic differences in lupus disease outcomes
- 2024
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Ingår i: Baillière's Best Practice & Research. - : Elsevier. - 1521-6942 .- 1532-1770. ; 37:4
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Forskningsöversikt (refereegranskat)abstract
- Health disparities in the prevalence and outcomes of systemic lupus erythematosus (SLE) are well documented across racial and ethnic groups. Similar to other chronic diseases, differences in disease severity among individuals with SLE are likely influenced by both genetic predisposition and multiple social determinants of health. However, research in SLE that jointly examines the genetic and environmental contributions to the disease course is limited, resulting in an incomplete understanding of the biologic and social mechanisms that underly health disparities. While research on health disparities can reveal inequalities and inform resource allocation to improve outcomes, research that relies on racial and ethnic categories to describe diverse groups of people can pose challenges. Additionally, results from research comparing outcomes across socially constructed groups without considering other contributing factors can be misleading. We herein comprehensively examine existing literature on health disparities in SLE, including both clinical studies that examine the relationship between self-reported race and ethnicity and disease outcomes and studies that explore the relationships between genomics and lupus outcomes. Having surveyed this body of research, we propose a framework for research examining health disparities in SLE, including ways to mitigate bias in future studies.
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| 31. |
- Petersson, IF, et al.
(författare)
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Osteoarthritis of the peripheral joints
- 2002
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Ingår i: Best Practice & Research: Clinical Rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 16:5, s. 741-760
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Forskningsöversikt (refereegranskat)abstract
- Osteoarthritis (OA) is a complex process affecting many different joint areas in the body. From a pathophysiological point of view some features are crucial for the diagnosis, such as cartilage fibrillation and thinning, subchondral sclerosis and the presence of osteophytes. From a clinical perspective, OA is the most prevalent rheumatic joint disorder, causing pain and stiffness of the joints and, for the individual, impaired function and health status. The aim of this chapter is to present current knowledge of definitions of OA, its presence in different populations and in different joint areas (the back excluded). Furthermore, methods of diagnosing and delineating clinically relevant forms of OA, now and in the future, are presented as well as current knowledge of the risk factors for developing and the factors for preventing OA.
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| 32. |
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| 33. |
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| 34. |
- Shaw, William S., et al.
(författare)
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Effects of workplace, family and cultural influences on low back pain : What opportunities exist to address social factors in general consultations?
- 2013
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Ingår i: Baillière's Best Practice & Research. - : Elsevier BV. - 1521-6942 .- 1532-1770. ; 27:5, s. 637-648
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Tidskriftsartikel (refereegranskat)abstract
- Social factors are widely acknowledged in behavioural models of pain and pain management, but incorporating these factors into general medical consultations for low back pain (LBP) can be challenging. While there is no compelling evidence that social factors contribute to LBP onset, these factors have been shown to influence functional limitation and disability, especially the effects of organisational support in the workplace, spousal support, family conflict and social disadvantage. A number of barriers exist to address such social factors in routine medical encounters for LBP, but there is emerging evidence that improving social and organisational support may be an effective strategy to reduce the negative lifestyle consequences of LBP. For clinicians to address these factors in LBP treatment requires a clearer psychosocial framework in assessment and screening, more individualised problem-solving efforts, more patient-centred interventions involving family, peers and workplace supports and a less biomechanical and diagnostic approach. (C) 2013 Elsevier Ltd. All rights reserved.
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| 35. |
- Tieu, J, et al.
(författare)
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Idiopathic inflammatory myositis
- 2016
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Ingår i: Best practice & research. Clinical rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 30:1, s. 149-168
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Tidskriftsartikel (refereegranskat)
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| 36. |
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| 37. |
- van Vollenhoven, RF, et al.
(författare)
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Biologics in SLE: towards new approaches
- 2013
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Ingår i: Best practice & research. Clinical rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 27:3, s. 341-349
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Tidskriftsartikel (refereegranskat)
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| 38. |
- Wilkie, Ross, et al.
(författare)
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Managing work participation for people with rheumatic and musculoskeletal diseases.
- 2020
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Ingår i: Baillière's Best Practice & Research. - : Elsevier. - 1521-6942 .- 1532-1770. ; 34:2
-
Forskningsöversikt (refereegranskat)abstract
- Improving work participation for individuals with rheumatic and musculoskeletal diseases (RMDs), has gained increasing interest over the last 10 years. New approaches are based upon increasing adoption of a biopsychosocial approach to improving work participation, incorporating evidence that health professionals within multidisciplinary teams have a key and critical role. In particular, interaction between health professionals and employers, and rehabilitation services that are linked to the workplace are key elements for improving work participation for people with RMDs. This review outlines recent research that underpins approaches for health professionals to develop their role in improving work participation for people with RMDs based on recent research; it outlines how to measure work-related outcomes in clinical practice, models of work participation, and approaches for health professionals to improve work participation outcomes. The potential for developing the role of health professionals in future years is also outlined.
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| 39. |
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| 40. |
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| 41. |
- Woolf, Anthony D., et al.
(författare)
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Prevention of musculoskeletal conditions in the developing world
- 2008
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Ingår i: Best Practice & Research: Clinical Rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 22:4, s. 759-772
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Tidskriftsartikel (refereegranskat)abstract
- Musculoskeletal conditions are an increasingly common problem across the globe due to increased longevity and increased exposure to risk factors such as obesity and lack of physical activity. The increase is predicted to be greatest in developing countries, and there is thus an urgent need for the implementation of strategies and policies that will prevent and control these conditions. The ideal is modification of the risk factors in the whole community, and this will have wide-ranging health benefits as these risk factors are common to other major conditions. Changing people's behaviour is a challenge; targeting those at highest risk is potentially more effective, providing that there are both affordable ways of identifying those at risk and affordable interventions. Early intervention in those with a condition such as rheumatoid arthritis is probably the most cost-effective approach, but requires diagnostic capacity - in clinical skills and/or technology - as well as access to care. There is now much evidence for what can be achieved, but the challenge is how to implement these different strategies in developing countries where there are competing priorities for limited resources. The key strategy is to raise awareness among the public, health professionals, and policy makers of the importance of musculoskeletal health, of what can be achieved by prevention and treatment, and to ensure that policies reflect this. It is also necessary to educate the public to know when to seek care, and health-care workers to recognize the early signs of musculoskeletal conditions.
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| 42. |
- Åkesson, Kristina, et al.
(författare)
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How to develop strategies for improving musculoskeletal health.
- 2007
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Ingår i: Best Practice & Research: Clinical Rheumatology. - : Elsevier BV. - 1532-1770 .- 1521-6942. ; 21:1, s. 5-25
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Tidskriftsartikel (refereegranskat)abstract
- Musculoskelecal conditions are a major cause of morbidity and evidence-based strategies - such as the European Action Towards Better Musculoskeletal Health - have been developed to reduce their incidence and impact on individuals and on society. This issue is based around that report. These strategies are inclusive of all major musculoskeletal conditions with recommendations for prevention and management, stratified for degree of risk in the population. The development of these strategies required a framework that would enable the integration of evidence and expert opinion and the development of this is discussed. Implementation must be addressed if these strategies are to be effective and the actions required of, and implications for, different stakeholders are considered. In that report, we find evidence to support the need for an integrated approach for improving musculoskeletal health, by an improvement by the whole population in lifestyle with increasing physical activity, avoidance of obesity, smoking and excess alcohol along with prevention of accidents and musculoskeletal injuries. However, the individual health gain will be small and, in addition, specific interventions need to be targeted at those with most to gain - i.e. those at highest risk or those with the early features of a musculoskeletal condition.
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| 43. |
- Allen, K. D., et al.
(författare)
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Osteoarthritis: Models for appropriate care across the disease continuum
- 2016
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Ingår i: Best Practice and Research: Clinical Rheumatology. - : Elsevier BV. - 1521-6942. ; 30:3, s. 503-535
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Tidskriftsartikel (refereegranskat)abstract
- Osteoarthritis (OA) is a leading cause of pain and disability worldwide. Despite the existence of evidence-based treatments and guidelines, substantial gaps remain in the quality of OA management. There is underutilization of behavioral and rehabilitative strategies to prevent and treat OA as well as a lack of processes to tailor treatment selection according to patient characteristics and preferences. There are emerging efforts in multiple countries to implement models of OA care, particularly focused on improving nonsurgical management. Although these programs vary in content and setting, key lessons learned include the importance of support from all stakeholders, consistent program delivery and tools, a coherent team to run the program, and a defined plan for outcome assessment. Efforts are still needed to develop, deliver, and evaluate models of care across the spectrum of OA, from prevention through end-stage disease, in order to improve care for this highly prevalent global condition. © 2016
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| 44. |
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| 45. |
- Briggs, Andrew M., et al.
(författare)
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Global health policy in the 21st century : Challenges and opportunities to arrest the global disability burden from musculoskeletal health conditions
- 2020
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Ingår i: Best Practice and Research: Clinical Rheumatology. - : Elsevier BV. - 1521-6942. ; 34:5
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Forskningsöversikt (refereegranskat)abstract
- The profound burden of disease associated with musculoskeletal health conditions is well established. Despite the unequivocal disability burden and personal and societal consequences, relative to other non-communicable diseases (NCDs), system-level responses for musculoskeletal conditions that are commensurate with their burden have been lacking nationally and globally. Health policy priorities and responses in the 21st century have evolved significantly from the 20th century, with health systems now challenged by an increasing prevalence and impact of NCDs and an unprecedented rate of global population ageing. Further, health policy priorities are now strongly aligned to the 2030 Sustainable Development Goals. With this background, what are the challenges and opportunities available to influence global health policy to support high-value care for musculoskeletal health conditions and persistent pain? This paper explores these issues by considering the current global health policy landscape, the role of global health networks, and progress and opportunities since the 2000–2010 Bone and Joint Decade for health policy to support improved musculoskeletal health and high-value musculoskeletal health care.
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| 46. |
- de Thurah, Annette, et al.
(författare)
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High-quality RMD rehabilitation and telehealth : Evidence and clinical practice
- 2020
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Ingår i: Best Practice and Research: Clinical Rheumatology. - : Elsevier BV. - 1521-6942. ; 34:2
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Forskningsöversikt (refereegranskat)abstract
- Within rheumatology, telehealth is essential to modern rehabilitation due to the demographic development with more and more elderly people. At present, telehealth solutions are used as part of the rehabilitation process in assessment, interventions and evaluation. Telehealth interventions are as effective as conventional follow-ups or self-management assessments, but the evidence on the effect is still sparse. Telehealth interventions seem to support a physically active lifestyle in the short term. In general, telehealth solutions are well received by patients, but the development must be based on user involvement, behaviour theory and the World Health Organisation principles of creating health literate organisations in order to ensure usability, effectiveness and further implementation.
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| 47. |
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| 48. |
- Foster, Helen E., et al.
(författare)
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Improving musculoskeletal health for children and young people – A ‘call to action’
- 2020
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Ingår i: Best Practice and Research: Clinical Rheumatology. - : Elsevier BV. - 1521-6942. ; 34:5
-
Forskningsöversikt (refereegranskat)abstract
- This chapter describes the musculoskeletal (MSK) context in children and young people as an important contributor to the global non-communicable disease burden. Through selected MSK conditions, we describe the impact on patients, families and communities and highlight the challenges that need to be addressed. We focus on opportunities for better working together and describe exemplar initiatives to raise awareness, workforce capacity building, models of care and research agendas to have a greater global context.
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| 49. |
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| 50. |
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