| 1. |
- Asare, Fredrick, 1979, et al.
(författare)
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Meditation over medication for irritable bowel syndrome? On exercise and alternative treatments for irritable bowel syndrome.
- 2012
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Ingår i: Current gastroenterology reports. - : Springer Science and Business Media LLC. - 1534-312X .- 1522-8037. ; 14:4, s. 283-9
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Forskningsöversikt (refereegranskat)abstract
- Complimentary alternative treatment regimens are widely used in irritable bowel syndrome (IBS), but the evidence supporting their use varies. For psychological treatment options, such as cognitive behavioral therapy, mindfulness, gut-directed hypnotherapy, and psychodynamic therapy, the evidence supporting their use in IBS patients is strong, but the availability limits their use in clinical practice. Dietary interventions are commonly included in the management of IBS patients, but these are primarily based on studies assessing physiological function in relation to dietary components, and to a lesser degree upon research examining the role of dietary components in the therapeutic management of IBS. Several probiotic products improve a range of symptoms in IBS patients. Physical activity is of benefit for health in general and recent data implicates its usefulness also for IBS patients. Acupuncture does not seem to have an effect beyond placebo in IBS. A beneficial effect of some herbal treatments has been reported.
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| 2. |
- Büsch, K, et al.
(författare)
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Impact of inflammatory bowel disease on disability
- 2014
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Ingår i: Current gastroenterology reports. - : Springer Science and Business Media LLC. - 1534-312X .- 1522-8037. ; 16:10, s. 414-
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Tidskriftsartikel (refereegranskat)
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| 3. |
- Simrén, Magnus, 1966, et al.
(författare)
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Update on Rome IV Criteria for Colorectal Disorders: Implications for Clinical Practice
- 2017
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Ingår i: Current Gastroenterology Reports. - : Springer Science and Business Media LLC. - 1522-8037 .- 1534-312X. ; 19:4
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Tidskriftsartikel (refereegranskat)abstract
- Purpose of Review: The purpose of the review was to provide an update of the Rome IV criteria for colorectal disorders with implications for clinical practice. Recent Findings: The Rome diagnostic criteria are expert consensus criteria for diagnosing functional gastrointestinal disorders (FGIDs). The current version, Rome IV, was released in May of 2016 after Rome III had been in effect for a decade. It is the collective product of committees that included more than 100 leading functional GI experts. For functional bowel and anorectal disorders, the majority of changes relative to Rome III are relatively minor and will have little impact on clinical practice. However, notable changes with potential impact on clinical practice and research include the changes in the diagnostic criteria for IBS, the modified approach for subtyping of IBS, the view on functional bowel disorders as a spectrum of disorders, and the new definition of fecal incontinence. Summary: New features in the Rome IV diagnostic criteria for functional bowel and anorectal disorders will likely have modest influence on clinical practice, with a few exceptions. © 2017, The Author(s).
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| 4. |
- Törnblom, Hans, 1966, et al.
(författare)
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Psychotropics, Antidepressants, and Visceral Analgesics in Functional Gastrointestinal Disorders
- 2018
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Ingår i: Current Gastroenterology Reports. - : Springer Science and Business Media LLC. - 1522-8037 .- 1534-312X. ; 20:12
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Tidskriftsartikel (refereegranskat)abstract
- Purpose of Review: The functional gastrointestinal disorders, or disorders of gut-brain interaction as defined by the Rome IV criteria, are the most common diagnostic entities in gastroenterology. Treatments that address the dysregulation of gut-brain interaction with these disorders are increasingly gaining interest as a better option than for example traditional analgesics, particularly opioids. Antidepressants, antianxiety and antipsychotic medications, and visceral analgesics, now termed neuromodulators, are included in this update addressing the evidence of treatment benefit in disorders of brain-gut interaction. Recent Findings: By a careful selection based on a multidimensional clinical profile, a decreased symptom burden, particularly regarding abdominal pain, nausea, and vomiting, as well as improved social function and quality of life, can be obtained by use of neuromodulators. There is good evidence for the peripheral neuromodulators from studies in bowel disorders, and the central neuromodulators both from indirect evidence in chronic pain disorders as well as selected disorders of brain-gut interaction. Summary: Basic knowledge about the pharmacologic properties and clinical use of neuromodulators in disorders of brain-gut interaction improves the treatment outcome and avoids use of traditional analgesics. © 2018, The Author(s).
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| 5. |
- Öhman, Lena, 1967, et al.
(författare)
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Intestinal microbiota and its role in irritable bowel syndrome (IBS).
- 2013
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Ingår i: Current gastroenterology reports. - : Springer Science and Business Media LLC. - 1534-312X .- 1522-8037. ; 15:5
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Forskningsöversikt (refereegranskat)abstract
- Gut microbiota alterations are increasingly being recognized as an important factor in the pathogenesis and pathophysiology of Irritable bowel syndrome (IBS). The onset of IBS symptoms after a bout of gastroenteritis comprises one of the strongest indications for the importance of gut microbiota for IBS. Moreover, recent studies have identified several susceptibility genes for IBS involved in the innate immunity and recognition of bacteria but also maintaining the integrity of the intestinal barrier. During recent years, it has also been demonstrated that IBS patients, or subgroups thereof, may have an altered microbiota composition relative to healthy individuals, mainly based on the analysis of fecal microbiota. Moreover, a positive effect of treatment with non-absorbable antibiotics and probiotics in IBS provides further indirect support for the relevance of gut microbiota alterations in IBS.
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| 6. |
- Ljungh, Åsa, et al.
(författare)
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The role of microorganisms in biliary tract disease.
- 2002
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Ingår i: Current Gastroenterology Reports. - 1534-312X. ; 4:2, s. 71-167
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Tidskriftsartikel (refereegranskat)abstract
- The biliary tract is normally sterile, but bile-tolerant bacteria are frequently isolated from patients with cholecystitis. Since the identification of about 25 Helicobacter species, some of which may grow in bile, studies have addressed the role of these organisms in primary biliary cirrhosis, primary sclerosing cholangitis, and cholelithiasis. Most of these bacteria show the presence of Helicobacter DNA or antigens in the bile tract and in liver samples. Altogether, data from studies on biliary and hepatic diseases, as well as pancreatic disorders, suggest that bile-tolerant Helicobacter species may induce a chronic infection with possible malignant transformation.
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