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2.
  • Andersson, Linus, 1979-, et al. (författare)
  • Chemosensory attention, habituation and detection in women and men
  • 2011
  • Ingår i: International Journal of Psychophysiology. - : Elsevier. - 0167-8760 .- 1872-7697. ; 79, s. 316-322
  • Tidskriftsartikel (refereegranskat)abstract
    •  The aim of this study was to investigate whether there are differences between women and men in how chemosensory stimuli are processed. Event-related potentials from 36 participants (18 men) showed that women had larger P3 amplitudes when attending, but not when ignoring CO 2 but not for n-butanol, compared with men. The main finding was that women and men differ in cognitive measures of chemosensory processing. 
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3.
  • Baluchnejadmojarad, Tourandokht, et al. (författare)
  • Neuroprotective Effect of Genistein in 6-Hydroxydopamine Hemi-parkinsonian Rat Model
  • 2008
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 69:3, s. 315-
  • Tidskriftsartikel (refereegranskat)abstract
    • A large body of experimental evidence supports a role for oxidative stress as a mediator of nerve cell death in Parkinson-s disease (PD). Phytoestrogens such as genistein have been reported to prevent neuronal degeneration caused by increased oxidative burden, therefore, this study examined whether genistein administration at a high dose would attenuate behavioral and structural abnormalities in an experimental model of PD in rat. For this purpose, unilateral intrastriatal 6-hydroxydopamine (6-OHDA, 12.5 μg/5 μL of saline-ascorbate)- lesioned rats were intraperitoneally pretreated with a single and high dose of genistein (10 mg/kg) 1 h before surgery. Apomorphine-induced rotations and the number of Nissl-stained neurons in the substantia nigra pars compacta (SNC) were counted after 2 weeks. Genistein administration could attenuate the rotational behavior in lesioned rats and protect the neurons of SNC against 6-OHDA toxicity. Genistein administration has a protective effect against 6-OHDA toxicity. 
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4.
  • Bechtereva, N P, et al. (författare)
  • PET study of brain maintenance of verbal creative activity.
  • 2004
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 53:1, s. 11-20
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper deals with the investigation of the brain organization of verbal creativity. Psychological tasks were designed in accordance with two main strategies used by volunteers in solving creative tasks. Regional cerebral blood flow (rCBF) was measured with positron emission tomography (PET) when performing two types of creative tasks in two groups of subjects, each type of the task organizing the creativity process in its own way. Brain correlates of creativity were revealed in the left parieto-temporal regions (Brodmann areas 39 and 40).
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5.
  • Bernhardsson, Jens, et al. (författare)
  • Changes in Event Related Potentials after exposure therapy for spider phobic individuals
  • 2016
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 108, s. 105-106
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • The present study was conducted in order to investigate treatment effects in spider phobic individuals on EEG and eye movements. A previous study has shown larger ERP amplitudes in the late positive complex (LPC) post treatment compared to pre treatment during exposure of spider pictures (Leutgeb, Schäfer, & Schienle, 2009). The authors hypothesize that the result might mirror an increase in attention towards the stimuli and reduced attentional avoidance generating enhanced LPC amplitude as a consequence of directing attention to the spider pictures post treatment. In the present study spider fearful individuals (treatment and waitlist group) and control individuals were measured with EEG and Eye tracking during exposure to pictures of spiders, snakes and flowers pre and post treatment. Based on behavioral and self-assessed measures treatment effects were high. Contrary to Leutgeb et al. (2009), our results showed relatively smaller LPC amplitudes post treatment during presentations of spider pictures. Moreover, the eye movement data indicated no avoidance from spider pictures compared to other pictures, neither pre nor post treatment. These results indicate that when individuals attend to visual threat stimuli, LPC amplitude differences follow the pattern of emotional significance and attention allocation.
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6.
  • Carlsson, Ingegerd, et al. (författare)
  • On the personality, cognition, and neurobiology of creativity
  • 2004
  • Ingår i: International Journal of Psychophysiology. - 0167-8760 .- 1872-7697. ; 54:1-2, s. 26-26
  • Konferensbidrag (refereegranskat)abstract
    • Two extreme groups of healthy male undergraduate students, either highly (n=12) or low creative (n=12), were pre-selected from a larger cohort (N=60) by way of the Creative functioning test (Smith & Carlsson, 1990). The two groups underwent measurements of regional cerebral blood-flow (rCBF). rCBF was measured during rest and during three verbal tasks (random order): Automatic speech (Auto), word fluency (FAS) and the unusual uses of objects test (Brick). The participant answered state and trait anxiety inventories after the rCBF measurements. On another day intelligence tests and a test of defense mechanisms were administered. Calculations were made of differences in blood flow levels between the FAS and the Brick measurements in the anterior prefrontal, frontotemporal and superior frontal regions. In accordance with prediction, repeated measure-ANOVAs showed that the creativity groups differed significantly in all three regions. The highly creative group had increases, or unchanged activity, while the low creative group had mainly decreases. The high creatives also had higher hemispheric means of CBF during rest compared to the low creative group. The highly creative group had higher trait anxiety than the low creative group. On the intelligence tests the low creative group was superior both on logical-inductive ability and on perceptual speed, while the groups were equal on verbal and spatial tests. Logical ability was negatively correlated with anxiety. Furthermore, the highly creative group had higher defensive variation than the low group. High defensive variability was positively correlated to the creativity test. The results are discussed in terms of flexible interaction between complementary functions in the two hemispheres.
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7.
  • Costa, Rui, et al. (författare)
  • Skin conductance responses to visual sexual stimuli
  • 2008
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 67:1, s. 64-69
  • Tidskriftsartikel (refereegranskat)abstract
    • Previous research showed that the asymmetrical direction of bilateral skin conductance responses (SCRs) remains constant regardless of task (with larger left SCRs in men and larger right SCRs in women). However, SCRs are controlled ipsilaterally by structures also associated with sexual arousal, hence it could be expected that larger right SCRs are specifically elicited by sexual stimuli. In order to test the two competing hypotheses, left and right SCR magnitude to three stimulus categories (sexually explicit, sexually non-explicit and neutral) were compared in 54 subjects (27 females). The direction of the asymmetry remained constant across stimulus types, however, unexpected sex differences occurred, as males had larger right SCRs and there was no lateralization in females. Interestingly, this interaction disappeared after controlling for indicators of subjective sexual arousal, suggesting that a specific (not previously hypothesized) processing of sexual information could take place.
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8.
  • Dang, Junhua, et al. (författare)
  • Individual differences in dopamine level modulate the ego depletion effect
  • 2016
  • Ingår i: International Journal of Psychophysiology. - : Elsevier. - 0167-8760 .- 1872-7697. ; 99, s. 121-124
  • Tidskriftsartikel (refereegranskat)abstract
    • Initial exertion of self-control impairs subsequent self-regulatory performance, which is referred to as the ego depletion effect. The current study examined how individual differences in dopamine level, as indexed by eye blink rate (EBR), would moderate ego depletion. An inverted-U-shaped relationship between EBR and subsequent self regulatory performance was found when participants initially engaged in self-control but such relationship was absent in the control condition where there was no initial exertion, suggesting individuals with a medium dopamine level may be protected from the typical ego depletion effect. These findings are consistent with a cognitive explanation which considers ego depletion as a phenomenon similar to switch costs that would be neutralized by factors promoting flexible switching.
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9.
  • Dhamija, Devika, et al. (författare)
  • Heritability of startle reactivity and affect modified startle
  • 2017
  • Ingår i: International Journal of Psychophysiology. - : Elsevier. - 0167-8760 .- 1872-7697. ; 115, s. 57-64
  • Tidskriftsartikel (refereegranskat)abstract
    • Startle reflex and affect-modified startle reflex are used as indicators of defensive reactivity and emotional processing, respectively. The present study investigated the heritability of both the startle blink reflex and affect modification of this reflex in a community sample of 772 twins ages 14–15 years old. Subjects were shown affective picture slides falling in three valence categories: negative, positive and neutral; crossed with two arousal categories: high arousal and low arousal. Some of these slides were accompanied with a loud startling noise. Results suggestedsex differences in meanlevels of startle reflex as well as in proportions of variance explained by genetic and environmental factors. Females had higher mean startle blink amplitudes for each valence-arousal slide category, indicating greater baseline defensive reactivity compared to males. Startle blink reflex in males was significantly heritable (49%), whereas in females, variance was explained primarily by shared environmental factors (53%) and non-shared environmental factors (41%). Heritability of affect modified startle (AMS) was found to be negligible in both males and females. These results suggest sex differences in the etiology of startle reactivity, while questioning the utility of the startle paradigm for understanding the genetic basis of emotional processing.
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  • Harmat, László, 1972-, et al. (författare)
  • Physiological correlates of the flow experience during computer game playing
  • 2015
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 97:1, s. 1-7
  • Tidskriftsartikel (refereegranskat)abstract
    • Flow is the subjective experience of effortless attention, reduced self-awareness, and enjoyment that typically occurs during optimal task performance. Previous studies have suggested that flow may be associated with a non-reciprocal coactivation of the sympathetic and parasympathetic systems and, on a cortical level, with a state of hypofrontality and implicit processing. Here, we test these hypotheses, using the computer game TETRIS as model task. The participants (n = 77) played TETRIS under three conditions that differed in difficulty (Easy < Optimal < Difficult). Cardiac and respiratory activities, and the average oxygenation changes of the prefrontal cortex were measured continuously with functional near infrared spectroscopy (INIRS) during performance. The Optimal condition was characterized by the highest levels of state flow, positive affect, and effortless attention. The associations between self-reported psychological flow and physiological measures were investigated using a series of repeated measures linear mixed model analyses. The results showed that higher flow was associated with larger respiratory depth and lower LF. The higher respiratory depth during high flow is indicative of a more relaxed state with an increased parasympathetic activity, and thus provides partial support for the main hypotheses. There was no association between frontal cortical oxygenation and flow, even at liberal thresholds; i.e. we found no support that flow is related to a state of hypofrontality.
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13.
  • Hasson, Dan, et al. (författare)
  • Psychosocial and physiological correlates of self-reported hearing problems in male and female musicians in symphony orchestras.
  • 2009
  • Ingår i: International journal of psychophysiology : official journal of the International Organization of Psychophysiology. - : Elsevier BV. - 1872-7697. ; 74:2, s. 93-100
  • Tidskriftsartikel (refereegranskat)abstract
    • Experimental and epidemiological research indicate an association between long-term stress and hearing problems, yet the mechanisms underlying these disorders are not yet fully established. Thus, in order to better understand the pathogenesis of stress-related hearing problems, the present study explored the symptoms and general physiological and psychosocial status of musicians in symphony orchestras. Orchestral musicians are an ideal group to study since physical, psychosocial, work-environmental and acoustic stressors are highly prevalent. The subjects where obtained from two different studies. The first group included 250 participants from 12 orchestras and is entitled "the epidemiological study". The second group, entitled "the longitudinal study", included 47 musicians who were assessed at five occasions (every half year) during two years. Thirty-one of the 47 participants were selected for sampling of physiological variables, i.e. 24-hour ECG to assess heart rate variability to evaluate the synergistic action of the autonomic system as well as saliva cortisol and testosterone levels. The results indicate that self-reported hearing problems are associated with perceived poorer psychosocial environment, as well as mental health symptoms and stress. High-frequency power of heart rate variability (parasympathetic activity) showed a negative relationship to hearing problems, implying a poorer ability to "unwind" from stress. Cortisol levels were not correlated to hearing problems whereas testosterone levels showed a tendency to be lower in subjects with hearing problems than in others. These findings provide evidence for a relationship between long-term stress and self-reported hearing problems and demonstrate a protective role of parasympathetic and anabolic activity on hearing status.
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  • Kallionpää, Roosa E., et al. (författare)
  • Single-subject analysis of N400 event-related potential component with five different methods
  • 2019
  • Ingår i: International Journal of Psychophysiology. - : Elsevier. - 0167-8760 .- 1872-7697. ; 144, s. 14-24
  • Tidskriftsartikel (refereegranskat)abstract
    • There are several different approaches to analyze event-related potentials (ERPs) at single-subject level, and the aim of the current study is to provide information for choosing a method based on its ability to detect ERP effects and factors influencing the results. We used data from 79 healthy participants with EEG referenced to mastoid average and investigated the detection rate of auditory N400 effect in single-subject analysis using five methods: visual inspection of participant-wise averaged ERPs, analysis of variance (ANOVA) for amplitude averages in a time window, cluster-based non-parametric testing, a novel Bayesian approach and Studentized continuous wavelet transform (t-CWT). Visual inspection by three independent raters yielded N400 effect detection in 85% of the participants in at least one paradigm (active responding or passive listening), whereas ANOVA identified the effect in 68%, the cluster-method in 59%, the Bayesian method in 89%, and different versions of t-CWT in 22–59% of the participants. Thus, the Bayesian method was the most liberal and also showed the greatest concordance between the experimental paradigms (active/passive). ANOVA detected significant effect only in cases with converging evidence from other methods. The t-CWT and cluster-based method were the most conservative methods. As we show in the current study, different analysis methods provide results that do not completely overlap. The method of choice for determining the presence of an ERP component at single-subject level thus remains unresolved. Relying on a single statistical method may not be sufficient for drawing conclusions on single-subject ERPs. 
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17.
  • Kleberg, Johan L., et al. (författare)
  • Spontaneous eye movements and trait empathy predict vicarious learning of fear
  • 2015
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 98:3, s. 577-583
  • Tidskriftsartikel (refereegranskat)abstract
    • Learning to predict dangerous outcomes is important to survival. In humans, this kind of learning is often transmitted through the observation of others' emotional responses. We analyzed eye movements during an observational/vicarious fear learning procedure, in which healthy participants (N = 33) watched another individual (learning model') receiving aversive treatment (shocks) paired with a predictive conditioned stimulus (CS +), but not a control stimulus (CS). Participants' gaze pattern towards the model differentiated as a function of whether the CS was predictive or not of a shock to the model. Consistent with our hypothesis that the face of a conspecific in distress can act as an unconditioned stimulus (US), we found that the total fixation time at a learning model's face increased when the CS + was shown. Furthermore, we found that the total fixation time at the CS + during learning predicted participants' conditioned responses (CRs) at a later test in the absence of the model. We also demonstrated that trait empathy was associated with stronger CRs, and that autistic traits were positively related to autonomic reactions to watching the model receiving the aversive treatment Our results have implications for both healthy and dysfunctional sodo-emotional learning.
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18.
  • Lennartsson, Anna Karin, et al. (författare)
  • Low heart rate variability in patients with clinical burnout
  • 2016
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760. ; 110, s. 171-178
  • Tidskriftsartikel (refereegranskat)abstract
    • © 2016 Elsevier B.V.Several studies have shown that acute psychosocial stress and chronic psychosocial stress reduce heart rate variability (HRV). It is likely that individuals suffering from burnout have reduced HRV, as a consequence of the long-term stress exposure. This study investigated HRV in 54 patients with clinical burnout (40 women and 14 men) and in 55 individuals reporting low burnout scores (healthy; 24 women and 31 men) and 52 individuals reporting high burnout scores (non-clinical burnout; 33 women and 19 men). The participants underwent a 300 s ECG recording in the supine position. Standard deviation of normal R-R intervals (SDNN) and the root mean square of successive normal interval differences (RMSSD) were derived from time domain HRV analysis. Frequency domain HRV measures; total power (TP), low frequency power (LF), high frequency power (HF), and LF/HF ratio were calculated. All HRV measures, except LF/HF ratio, were lower in the clinical burnout patients compared to both the non-clinical burnout group and the healthy group. The difference was larger between the patients and the healthy group than between the patients and the non-clinical burnout group. HRV did not differ significantly between the non-clinical burnout group and the healthy group. Low HRV in burnout patients may constitute one of the links to associated adverse health, since low HRV reflects low parasympathetic activity – and accordingly low anabolic/regenerative activity.
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19.
  • Lennartsson, Anna-Karin, et al. (författare)
  • Sex steroid levels temporarily increase in response to acute psychosocial stress in healthy men and women
  • 2012
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 84:3, s. 246-253
  • Tidskriftsartikel (refereegranskat)abstract
    • It is well known that acute psychosocial stress activates the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system (SNS). However, the effect of acute psychosocial stress on the hypothalamic-pituitary-gonadal (HPG) axis and levels of sex steroids are less known. The aim of this study was to investigate the effect of acute psychosocial stress on serum concentrations of sex steroids in healthy men and women. Twenty men and 19 women (age 30-50 years) underwent Trier Social Stress Test (TSST), a tool for investigating psychobiological stress responses in a laboratory setting. Blood samples were collected before, directly after the stress test, and after 30 min of recovery. Concentrations of androgens were measured with high specificity LC-MS/MS method; concentrations of cortisol, estradiol and sex hormone-binding globulin were determined using immunoassays. In both men and women we observed significantly elevated levels of testosterone, estradiol, androstenedione and sex hormone binding globulin along with significantly increased adrenocorticotropic hormone (ACTH), serum cortisol, heart rate, systolic blood pressure (SBP), and diastolic blood pressure (DBP) as a response to the stressor. Thus, even though the HPG axis and the production of sex steroids may be inhibited during prolonged periods of stress, the sex steroid levels may increase in the initial phase of acute psychosocial stress. (C) 2012 Elsevier B.V. All rights reserved.
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  • Nordin, Steven, et al. (författare)
  • Evaluation of auditory, visual and olfactory event-related potentials for comparing interspersed- and single-stimulus paradigms
  • 2011
  • Ingår i: International Journal of Psychophysiology. - : Elsevier. - 0167-8760 .- 1872-7697. ; 81:3, s. 252-262
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: An interspersed-stimulus paradigm (ISP) for event-related potential (ERP) recordings in which different sensory modality stimuli are presented within the same test session was developed to minimize recording time and facilitate modality comparison. The present study compared the ISP with a single-stimulus paradigm (SSP), using auditory, visual, and olfactory stimuli. Method: Normal participants (n=16) were assessed on two independent test occasions to obtain data on inter-paradigm and test-retest reliability. Peak amplitude/latency and area measures were obtained for the N1, P2 and P3 peaks for each paradigm. Results: Except for larger auditory and visual P3 peaks and smaller visual P2 peaks in the ISP, no significant differences in amplitudes or latencies were found between the two paradigms. Correlation coef ficients between paradigms were generally fairly high (amplitude mean r=0.76; latency r=0.42). Test–retest reliability within paradigms for amplitudes (ISP r=0.70; SSP r=0.68) and latencies (ISP r=0.44; SSP r=0.42) was similar across paradigms. Conclusion: Thefindings suggest that the ISP, compared to the SSP, produces, in general, highly comparable auditory, visual, and olfactory peak amplitudes and latencies, and comparable reliability estimates, even though the ISP takes much less time to record (25 vs. 50 min). The larger auditory and visual P3 peaks and smaller visual P2 peaks in the ISP may be attributable to a less predictable stimulus environment. Thus, this method enables systematic comparisons of ERP peaks across sensory modalities while reducing testing time. Practical implications are discussed.
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23.
  • Noreika, Valdas, et al. (författare)
  • Early-night serial awakenings as a new paradigm for studies on NREM dreaming
  • 2009
  • Ingår i: International Journal of Psychophysiology. - : Elsevier. - 0167-8760 .- 1872-7697. ; 74:1, s. 14-18
  • Tidskriftsartikel (refereegranskat)abstract
    • A new experimental paradigm called "Early-Night Serial Awakenings" (ENSA) was explored to find out its strengths and weaknesses for psychophysiological studies of NREM sleep dreaming. Five participants spent 20 experimental nights in the sleep laboratory, and were serially awakened with approximately 24-minute intervals during Stages 2 and 3 of NREM sleep. As a total, 164 awakenings were conducted during the sessions that lasted on average 193 min. Altogether, 30% of NREM sleep awakenings led to dream reports, 39% to reports of white dreaming, and 31% to reports of dreamless sleep. Results also show that sleep EEG spectral power, dream recall frequency as well as dream complexity remained stable throughout the serial awakening sessions. We conclude that, as ENSA dreams appeared to be static and very limited in content, the paradigm we identified could be used in future studies to reveal the psychophysiological mechanisms of relatively simple forms of early-night NREM sleep dreaming. (c) 2009 Elsevier B.V. All rights reserved.
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24.
  • Peira, Nathalie, et al. (författare)
  • Controlling the emotional heart : Heart rate biofeedback improves cardiac control during emotional reactions
  • 2014
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 91:3, s. 225-231
  • Tidskriftsartikel (refereegranskat)abstract
    • When regulating negative emotional reactions, one goal is to reduce physiological reactions. However, not all regulation strategies succeed in doing that. We tested whether heart rate biofeedback helped participants reduce physiological reactions in response to negative and neutral pictures. When viewing neutral pictures, participants could regulate their heart rate whether the heart rate feedback was real or not. In contrast, when viewing negative pictures, participants could regulate heart rate only when feedback was real. Ratings of task success paralleled heart rate. Participants' general level of anxiety, emotion awareness, or cognitive emotion regulation strategies did not influence the results. Our findings show that accurate online heart rate biofeedback provides an efficient way to down-regulate autonomic physiological reactions when encountering negative stimuli.
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  • Pfaltz, Monique C., et al. (författare)
  • Physical activity and respiratory behavior in daily life of patients with panic disorder and healthy controls
  • 2010
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 78:1, s. 42-49
  • Tidskriftsartikel (refereegranskat)abstract
    • Panic disorder (PD) has been linked in laboratory investigations to respiratory alterations, particularly persistent respiratory variability. However, studies of PD respiratory pattern outside the laboratory are rare, have not controlled for the confounding influence of varying levels of physical activity, and have not addressed whether abnormalities in respiratory pattern vary depending on the intensity of physical activity. Cognitive and biological theories of PD, in fact, predict that respiratory alterations may be particularly pronounced when patients are physically active. This study assessed physical activity and respiratory pattern of 26 PD patients and 26 healthy controls (HC) during two waking periods of daily life (9:00-21:00) one week apart. Respiratory data were stratified for predefined levels of physical activity (inactivity, minimal movement, slow/moderate/fast walking, and running) and analyzed using linear mixed models. Groups did not generally differ in respiratory measures, although PD patients did show elevated variability of absolute levels of tidal volume during minimal movement and slow walking (root mean squared successive differences). Other ways of analyzing tidal volume variability based on relative levels, percentage of sighing, or pooled activity levels did not substantiate this finding. Amount of time spent at different activity levels did not differ between groups, which is at variance with studies linking anticipatory anxiety with motoric agitation, and PD with self-reported avoidance of exercise. In conclusion, results provided little evidence for respiratory abnormalities or central respiratory dysregulation in PD at varying levels of activity, although instability of tidal volume regulation during low activity remains a possibility. Our research approach indicates the usefulness of stratification of real life data on the basis of levels of activity, as well as how ambulatory assessment strategies, complementarily to laboratory studies, may improve understanding of biological and psychological factors contributing to development and maintenance of PD and other anxiety disorders. © 2010 Elsevier B.V.
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27.
  • Rosencrantz, Bella, et al. (författare)
  • Affective visual event-related potentials : arousal, valence, and reptition effects for normal and disorted pictures
  • 2008
  • Ingår i: International Journal of Psychophysiology. - : Elsevier. - 0167-8760 .- 1872-7697. ; 67:2, s. 114-123
  • Tidskriftsartikel (refereegranskat)abstract
    • Event-related potentials (ERPs) were used to assess arousal (low, high), valence (negative, positive), and stimulus repetition effects for normal and distorted images from the International Affective Pictures System (IAPS). Distorted stimuli were constructed by dividing each image into small squares and rearranging the segments randomly to produce a "scrambled" picture. Event-related potentials (ERPs) were elicited by presenting the normal and scrambled images as target stimuli, with a repeated visual pattern used as the standard stimulus. Participants (N=32) were instructed to press a button to the targets and ignore the standard. Stimulus repetition effects were assessed by presenting each stimulus twice in the normal and scrambled condition. High-arousal stimuli yielded larger late positive components for both the normal and scrambled pictures. No overall valence effects were obtained, but arousal and valence influenced component amplitudes for middle-latency ERPs from the scrambled stimuli. For the normal pictures, stimulus repetition was associated with increased component amplitudes for all potentials and decreased RTs of all affective categories. For the scrambled pictures, no repetition changes were obtained. The findings suggest that stimulus arousal level contributes more than valence to affective ERP measures for normal as well as perceptually distorted pictures. Stimulus repetition engages memory for previous normal picture items but is not influenced by affective category. Theoretical implications are discussed.
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28.
  • Rämä, Pia, et al. (författare)
  • Effect of language experience on selective auditory attention : An event-related potential study
  • 2018
  • Ingår i: International Journal of Psychophysiology. - : Elsevier BV. - 0167-8760 .- 1872-7697. ; 127, s. 38-45
  • Tidskriftsartikel (refereegranskat)abstract
    • Dual language experience has typically been shown to improve various executive control functions. We investigatedwith event-related brain potentials (ERPs) recorded from early (natively) bilingual speakers andcontrol participants whether it also affects auditory selective attention. We delivered to our participants two tonestreams, one to the left and one to the right ear. Both streams consisted of standard tones and two types ofinfrequent deviant tones which had either an enhanced duration or intensity. The participants were instructed toattend either to the right or left stream and to detect longer-duration deviants in the attended stream. The resultsshowed that the early bilinguals did not outperform the controls in target detection accuracy or speed. However,the late portion of the attention-related ERP modulation (the negative difference, Nd) was larger over the lefthemisphere in the early bilinguals than in the controls, suggesting that the maintenance of selective attention orfurther processing of selectively attended sounds is enhanced in the bilinguals. Moreover, the late reorientingnegativity (RON) in response to intensity-deviant tones was larger in the bilinguals, suggesting more efficientdisengagement of attention from distracting auditory events. Hence, our results demonstrate that brain responsesassociated with certain aspects of auditory attention are enhanced in the bilingual adults, indicating that earlydual language exposure modulates the neuronal responsiveness of auditory modality.
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  • Skarman, Erik, et al. (författare)
  • EEG waves as chaotic self-oscillations
  • 2002
  • Ingår i: International Journal of Psychophysiology. - 0167-8760 .- 1872-7697. ; 45:1-2, s. 138-138
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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31.
  • Stenhammar, Elin, et al. (författare)
  • Levonorgestrel intrauterine device and depression : A Swedish register-based cohort study
  • 2023
  • Ingår i: International Journal of Psychophysiology. - : Elsevier. - 0167-8760 .- 1872-7697. ; 193
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The levonorgestrel intrauterine device (LNG-IUD) is traditionally viewed as a safe contraceptive with limited systemic effects. However, three recent studies have indicated an increased risk of depression subsequent to LNG-IUD use. This study aimed to examine the potential associated risk between LNG-IUDs and depression, and determine which women are at risk.Methods: This longitudinal cohort study was based on data from seven Swedish national population-based registers. All Nordic-born women aged 15-24 years residing in Sweden between 2010 and 2017 were included. Cox regression was implemented to estimate the adjusted hazard ratio (AHR) for developing depression, defined as first depression diagnosis or redeemed prescription for antidepressant treatment. We adjusted for age, education level, parental country of origin, parental psychiatric health, previous hormonal contraceptive use and medical indications for contraceptive use.Findings: 703,157 women were included in the analysis. The LNG-IUD was associated with 57 % increased risk of depression [AHR 1.57 (95 % CI 1.51-1.64)]. The greatest risk increase was seen in adolescent women [AHR 2.57, (95 % CI 2.36-2.80)] and women who used the LNG-IUD as their first hormonal contraceptive method [AHR 1.63, (95 % CI 1.50-1.78)]. The risk of depression decreased at the end of study period [AHR 1.43, (95 % CI 1.36-1.51)], once the LNG-IUD became more widely accessible among nulliparous women.Conclusions: Adolescent women who use the LNG-IUD as their first-ever hormonal contraceptive are at increased risk of developing depression. However, additional impact from confounding factors is likely as risk estimates decreased over the study period. Further research needs to determine if there is a causal relationship between LNG-IUDs and depression.
  •  
32.
  • Venables, N. C., et al. (författare)
  • Evidence of a prominent genetic basis for associations between psychoneurometric traits and common mental disorders
  • 2017
  • Ingår i: International Journal of Psychophysiology. - Amsterdam : Elsevier. - 0167-8760 .- 1872-7697. ; 115, s. 4-12
  • Tidskriftsartikel (refereegranskat)abstract
    • Threat sensitivity (THT) and weak inhibitory control (or disinhibition; DIS) are trait constructs that relate to multiple types of psychopathology and can be assessed psychoneurometrically (i.e., using self-report and physiological indicators combined). However, to establish that psychoneurometric assessments of THT and DIS index biologically-based liabilities, it is important to clarify the etiologic bases of these variables and their associations with clinical problems. The current work addressed this important issue using data from a sample of identical and fraternal adult twins (N = 454). THT was quantified using a scale measure and three physiological indicators of emotional reactivity to visual aversive stimuli. DIS was operationalized using scores on two scale measures combined with two brain indicators from cognitive processing tasks. THT and DIS operationalized in these ways both showed appreciable heritability (0.45, 0.68), and genetic variance in these traits accounted for most of their phenotypic associations with fear, distress, and substance use disorder symptoms. Our findings suggest that, as indices of basic dispositional liabilities for multiple forms of psychopathology with direct links to neurophysiology, psychoneurometric assessments of THT and DIS represent novel and important targets for biologically-oriented research on psychopathology.
  •  
33.
  • Åhs, Fredrik, et al. (författare)
  • Human serotonin transporter availability predicts fear conditioning
  • 2015
  • Ingår i: International Journal of Psychophysiology. - : Elsevier. - 0167-8760 .- 1872-7697. ; 98:3 Pt 2, s. 515-9
  • Tidskriftsartikel (refereegranskat)abstract
    • Serotonin facilitates fear learning in animals. We therefore predicted that individual differences in the capacity to regulate serotonergic transmission in the human neural fear circuit would be inversely related to fear conditioning. The capacity to regulate serotonergic transmission was indexed by serotonin transporter availability measured with [(11)C]-DASB positron emission tomography. Results indicate that lower serotonin transporter availability in the amygdala, insula and dorsal anterior cingulate cortex predicts enhanced conditioned autonomic fear responses. Our finding supports serotonergic modulation of fear conditioning in humans and may aid in understanding susceptibility for developing anxiety conditions such as post-traumatic stress disorder.
  •  
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