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Sökning: L773:9781457703812

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1.
  • Erlöv, Tobias, et al. (författare)
  • A Method to Measure Shear Strain with High Spatial Resolution in the Arterial Wall Non-Invasively in vivo by Tracking Zero-Crossings of B-Mode Intensity Gradients
  • 2010
  • Ingår i: Proceedings - IEEE Ultrasonics Symposium. - 9781457703812 ; , s. 491-494
  • Konferensbidrag (refereegranskat)abstract
    • We have previously shown that there is a distinct longitudinal movement of the arterial wall during a cardiac cycle. This movement is larger in the intima-media region than in the adventitial region which introduces a substantial shear strain within the arterial wall. Our previously developed echo-tracking algorithm measured this shear strain by tracking two separate echoes, one in the intima-media region and one in the adventitia region and thus only a linear distribution was evaluated. The objective of this study was to suggest and evaluate a new improved method which can measure the intramural shear strain with higher spatial resolution and thereby provide more information on this new and rather unknown phenomenon. The mean maximum shear strain was 0.82 radians with a standard deviation of 0.17 radians and a CV-value of 14.2%. The total mean difference in measured longitudinal movement between the new and previous method was 10μm with a standard deviation of 90μm and a CV-value of 12.8%. The spatial distribution of the intramural shear strain seems to be very non-linear with a large amount of shear strain occurring in a small section around the transition between the media and adventitia layers.
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2.
  • Holst, Maria, et al. (författare)
  • Phase-locked magnetomotive ultrasound imaging of superparamagnetic iron-oxide nanoparticles
  • 2010
  • Ingår i: 2010 IEEE International Ultrasonics Symposium, IUS 2010. - 9781457703829 - 9781457703812 ; , s. 1007-1010
  • Konferensbidrag (refereegranskat)abstract
    • It has recently been shown that superparamagnetic iron oxide nanoparticles (SPIO-NP) can be used as ultrasound contrast agents, by moving the particles using a time-varying external magnetic field and thereby moving nanoparticle laden tissue. However, the difficulty to distinguish magneto-motive motion from indirect motion induced outside areas containing nanoparticles, or other motion artifacts, which restrict the use in vivo, is not well reported. Using a high-frequency linear array system we found that displacements outside nanoparticle-laden areas could be in the same range as the displacement in areas containing nanoparticles. We also found in our setup that the movement in areas between the nanoparticles areas were approximately radians out of phase relative the nanoparticles areas. To suppress undesirable signals we developed an algorithm based on frequency-tracking and phase-locking, where the energy of the processed signal is color-coded and overlaid on the B-mode image. The signal-to-clutter ratio showed a 14.5 dB improvement between the image color-coded with the total power and the image coded with regard to phase and frequency. The capability to distinguish areas containing SPIO-NP from those that do not is a crucial step for detection of nanoparticles in vivo.
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  • Resultat 1-2 av 2
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Cinthio, Magnus (2)
Jansson, Tomas (2)
Persson, Hans W (2)
Olsson, Fredrik (1)
Nilsson, Jan (1)
Erlöv, Tobias (1)
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Rydén Ahlgren, Åsa (1)
Lindström, Kjell (1)
Fredriksson, Sarah (1)
Holst, Maria (1)
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