| 1. |
- Abedan Kondori, Farid, 1983-, et al.
(författare)
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3D Active Human Motion Estimation for Biomedical Applications
- 2012
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Ingår i: World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China. - Berlin, Heidelberg : Springer Berlin/Heidelberg. - 9783642293047 - 9783642293054 ; , s. 1014-1017
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Konferensbidrag (refereegranskat)abstract
- Movement disorders forbid many people from enjoying their daily lives. As with other diseases, diagnosis and analysis are key issues in treating such disorders. Computer vision-based motion capture systems are helpful tools for accomplishing this task. However Classical motion tracking systems suffer from several limitations. First they are not cost effective. Second these systems cannot detect minute motions accurately. Finally they are spatially limited to the lab environment where the system is installed. In this project, we propose an innovative solution to solve the above-mentioned issues. Mounting the camera on human body, we build a convenient, low cost motion capture system that can be used by the patient while practicing daily-life activities. We refer to this system as active motion capture, which is not confined to the lab environment. Real-time experiments in our lab revealed the robustness and accuracy of the system.
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| 2. |
- Alrifaiy, Ahmed, et al.
(författare)
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Hypoxia on a chip - a novel approach for patch-clamp studies in a microfluidic system with full oxygen control
- 2012
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Ingår i: World Congress on Medical Physics and Biomedical Engineering, May 26-31, 2012, Beijing, China. - Berlin : Encyclopedia of Global Archaeology/Springer Verlag. - 9783642293047 - 9783642293054 ; , s. 313-316
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Konferensbidrag (refereegranskat)abstract
- A new approach to perform patch-clamp experiments on living cells under controlled anoxic and normoxic conditions was developed and tested. To provide an optimal control over the oxygen content and the biochemical environment a patch-clamp recording micropipette was integrated within an oxygen tight poly-methyl methacrylate (PMMA) based microchip. The oxygen content within the microfluidic chamber surrounding patch-clamp micropipette was maintained at 0.5-1.5 % by a continuous flow of artificial extracellular solution purged with nitrogen. The nerve and glial cells acutely obtained from the male rat brain were trapped by the optical tweezers and steered towards the patch-clamp micropipette through the channels of the microchip in order to achieve a close contact between the pipette and the cellular membrane. The patch-clamp recordings revealed that optical tweezers did not affect the electrophysiological properties of the tested cells suggesting that optical trapping is a safe and non-traumatizing method to manipulate living cells in the microfluidic system. Thus, our approach of combining optical tweezers and a gas-tight microfluidic chamber may be applied in various electrophysiological investigations of single cells were optimal control of the experimental conditions and the sample in a closed environment are necessary.
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| 3. |
- Lindahl, Olof, et al.
(författare)
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A Triple-Helix model for refining biomedical engineering research into spin-off companies for the health care market
- 2013
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Ingår i: World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China. - Berlin, Heidelberg : Springer. - 9783642293047 - 9783642293054 ; , s. 2088-2090
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Konferensbidrag (refereegranskat)abstract
- Triple-Helix activities at the centre for biomedical engineering and physics (CMTF) have generated growth both in academia at the universities and in the industry in Northern Sweden. Cooperation was built up between the 26 research projects and about 15 established companies in the field of biomedical engineering. The established researcher - owned company for business development of the research results from the CMTF, CMTF Business Development Co Ltd, has so far launched one spin-off company and has 15 new business leads to business develop. The activities have also increased the interest for commercial and entrepreneurship questions among the scientists in the centre. So far a total of seven spin-off companies have resulted from the CMTF-research since the year 2000.
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| 4. |
- Åstrand, Anders, et al.
(författare)
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Stiffness measurements on spherical surfaces of prostate models using a resonance sensor
- 2013
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Ingår i: World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China. - Berlin, Heidelberg : Springer Berlin/Heidelberg. - 9783642293047 - 9783642293054 ; , s. 1401-1404
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Konferensbidrag (refereegranskat)abstract
- Prostate cancer is one of the most common formsof cancer among men in Europe and the United States.Piezoelectric resonance sensors can be used in medicalresearch for measurements of stiffness of human tissue.Cancer tissue is usually stiffer and has different biomechanicalproperties compared to healthy tissue. The frequency shiftobserved when a piezoelectric resonance sensor comes intocontact with a tissue surface has been suggested to correlatewith the stiffness variations, e.g. due to cancer. An instrumenthas been developed, with which it is possible to scan flat andspherical objects and where the sensor can be tilted fordifferent contact angles. Measurements performed in thisstudy on spherical tissue models made of silicone, showed theimportance of keeping the contact angle perpendicular to thesurface of the sphere. The results are promising for futurestudies on prostate tissue to complete the evaluation of theinstrument.
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| 5. |
- Andersson, Jonas, 1975-, et al.
(författare)
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The Use of Liquid Ionization Chambers in Radiation Dosimetry
- 2012
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Ingår i: World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012 Beijing, China. - : Springer. - 9783642293047
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Konferensbidrag (refereegranskat)abstract
- Liquid ionization chambers (LICs) have found applications in many fields in radiation dosimetry, e.g. IMRT, hadron therapy, brachytherapy and computed tomography. The wide range of applications is made possible due to the high sensitivity of LICs, allowing them to be manufactured with small physical dimensions of the chamber body and the effective measurement volume. Furthermore, the commonly used liquids (such as isooctane) have radiation absorption characteristics similar to water, introducing only small fluence perturbation effects as compared to conventional dosimeters. The small dimension of the effective measurement volume is beneficial for the quantification of radiation beams with steep gradients, while retaining a high measurement signal with good statistical properties. However, the interpretation of measurement results is not straight-forward due to several factors influencing their performance. Here, the main problems are recombination effects and particle type- and energy dependence, which may cause severe non-linear effects. The loss of measurement signal in LICs is due to both initial and general recombination. In the present work it is shown that the general recombination effect can be treated with in a similar manner as for air-filled ionization chambers, while there are currently no theories that adequately describe the initial recombination effect for LICs. Furthermore, the relationship between energy dependence and recombination losses in LICs are evaluated at different radiation qualities. Recently developed methods for the correction of general recombination losses in LICs are discussed and their validity evaluated.
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| 6. |
- Guo, Yu, et al.
(författare)
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Localization of prostate cancer based on fuzzy fusion of multispectral MRI
- 2013
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Ingår i: IFMBE Proceedings. - Berlin, Heidelberg : Springer. - 9783642293047 ; , s. 1844-1846
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Konferensbidrag (refereegranskat)abstract
- Accurate prostate cancer localization with noninvasive imaging can be used to guide biopsy, radiotherapy and surgery as well as to monitor disease progression [1]. Published studies have shown multispectral magnetic resonance imaging (MRI), i.e., a combination of multiple types of MR images, as a promising noninvasive imaging technique for the localization of prostate cancer.
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