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| 2. |
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| 3. |
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| 4. |
- Abrahamsson, Cecilia, et al.
(författare)
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Alterations of temporomandibular disorders before and after orthognathic surgery
- 2007
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Ingår i: Angle orthodontist. - : Angle Orthodontist. - 0003-3219 .- 1945-7103. ; 77:4, s. 729-734
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Forskningsöversikt (övrigt vetenskapligt/konstnärligt)abstract
- OBJECTIVE: To answer the question whether orthognathic surgery does affect the prevalence of signs and symptoms of temporomandibular disorders (TMDs). MATERIALS AND METHODS: A literature survey in the PubMed and Cochrane Library electronic databases was performed and covered the period from January 1966 to April 2006. The inclusion criteria were controlled, prospective or retrospective studies comparing TMDs before and after orthognathic surgery in patients with malocclusion. There were no language restrictions, and three reviewers selected and extracted the data independently. The quality of the retrieved articles was evaluated by four reviewers. RESULTS: The search strategy resulted in 467 articles, of which 3 met the inclusion criteria. Because of few studies with unambiguous results and heterogeneity in study design, the scientific evidence was insufficient to evaluate the effects that orthognathic surgery had on TMD. Moreover, the studies had problems with inadequate selection description, confounding factors, and lack of method error analysis. CONCLUSION: To obtain reliable scientific evidence, additional well-controlled and well-designed studies are needed to determine how and if orthognathic surgery alters signs and symptoms of TMD.
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| 5. |
- Abrahamsson, Cecilia
(författare)
-
Masticatory function and temporomandibular disorders in patients with dentofacial deformities : studies before and after orthodontic and orthognathic treatment
- 2013
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Ca 30 % av Sveriges befolkning genomgår någon gång i livet behandling med tandreglering. I de fall där bettavvikelsen är mer omfattande är enbart tandreglering inte tillräckligt för att uppnå ett bra bett. Istället kombinerar man tandregleringen med en kirurgisk förflyttning av käkarna s.k. ortognat kirurgi. Dessa patienter besväras ofta, före behandling, av smärta och funktionsstörningar i käkar och tuggmuskler och är dessutom ofta missnöjda med sitt utseende. Då denna behandling är omfattande, kostsam och inte helt utan komplikationer är det av stort intresse att undersöka utfallet av behandlingen och om denna motsvarar förväntningarna hos patienterna.Tidigare studier som har utvärderat utfallet av tandreglering i kombination med ortognat kirurgi har kommit fram till motsägelsefulla slutsatser vad gäller hur behandlingen har påverkat förekomsten av smärta och funktionsstörningar i käkar och tuggmuskulatur.Det övergripande syftet med denna avhandling är att i en serie studier, före och efter ortognat kirurgi, utvärdera och jämföra före- komsten av smärta och käkfunktionsstörningar hos patienter med stora bettavvikelser.Avhandlingen är baserad på följande studier:delarbete I är en systematisk litteraturöversikt med följande frågeställning:Påverkar ortognat kirurgi förekomsten av smärta och funktionsstörningar i käkleder och tuggmuskulatur?I studien utvärderas den tillgängliga vetenskapliga litteraturen ur ett evidensbaserat perspektiv. Översikten omfattade tidsperioden januari 1966 till april 2006 och utökades senare till maj 2013.Slutsatser i delarbete I• Det finns ett otillräckligt vetenskapligt underlag för om förekomsten av diagnostiserad smärta och funktionsstörning i käkleder och tuggmuskler minskar efter ortognat kirurgi• Det vetenskapliga underlaget är begränsat när det gäller en minskning av palpationsömhet i tuggmuskler efter ortognata kirurgi.• Det finns ett otillräckligt vetenskapligt underlag för om förekomsten av käkledsljud påverkas av ortognat kirurgi.• Det behövs ytterligare en studier som är av hög eller medelhög kvalitet för att på ett evidensbaserat sätt kunna styrka behandlingsutfallet av ortognat kirurgi när det gäller smärta och funktionsstörningar i käkleder och tuggmuskler.delarbetena II och III är kontrollerade studier som undersöker förekomsten av smärta och funktionsstörningar i käkleder och tuggmuskler hos patienter med stora bettavvikelser, i jämförelse med personer med eller utan små bettavvikelser (ej i behov av tandreg- lering). Patienterna var remitterade för behandling med ortognat kirurgi. I delarbete III, som är en longitudinell uppföljningsstudie, analyseras hur förekomsten av smärta och funktionsstörningar i käkleder och tuggmuskler påverkas av behandlingen och även hur patienttillfredsställelsen är tillgodosedd.Slutsatser i delarbete II och III• Patienter som ska behandlas med ortognat kirurgi har mer smärta och funktionsstörningar i käkleder och tuggmuskler jämfört med kontrollgruppen.• Patienter som genomgått ortognat kirurgi har ett positivt behandlingsutfall avseende smärta från käkleder och tuggmuskler.• Efter behandling är förekomsten av smärta och funktionsstörningar i käkleder och tuggmuskler låg och i nivå med den i kontrollgruppen.Delarbete IV utvärderar den självupplevda tuggförmågan och den testade tuggprestationen före och efter ortognat kirurgi hos samma individer som i studie II och III.Slutsatser i delarbete IV• Patienter med stora bettavvikelser har innan ortognat kirurgi en sämre självupplevd tuggförmåga och testad tuggprestation jämfört med kontrollgruppen.• Efter behandling förbättras både den självupplevda tuggförmågan och tuggprestationen.Klinisk betydelse:Patienter som har stora bettavvikelser och dessutom smärta och funktionsstörningar i käkleder och tuggmuskler har oftast ett positivt behandlingsutfall efter ortognat kirurgi. Dessutom förbättras den självupplevda tuggförmågan och den testade tuggprestationen efter behandlingen. Patienter med stora bettavvikelser som ska behandlas med tandreglering i kombination med ortognat kirurgi kan därför rekommenderas behandlingen för möjlighet till minskade besvär från tuggmuskler och käkleder och förbättrad tuggförmåga.
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| 6. |
- Abrahamsson, Cecilia, et al.
(författare)
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Masticatory function in patients with dentofacial deformities before and after orthognathic treatment : a prospective, longitudinal, and controlled study
- 2015
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Ingår i: European Journal of Orthodontics. - : Oxford University Press. - 0141-5387 .- 1460-2210. ; 37:1, s. 67-72
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: The aim of this study was to investigate the self-estimated masticatory ability and masticatory performance in patients with dentofacial deformities before and after orthognathic treatment; in comparison to an age- and gender-matched control group. SUBJECTS AND METHODS: The masticatory ability and masticatory performance were evaluated in 121 consecutive patients (treatment group), referred for orthognathic treatment. Eighteen months after treatment, 98 patients (81%) completed a follow-up examination. Masticatory ability was assessed on a visual analog scale, while the masticatory performance was evaluated by a masticatory test using round silicon tablets. Signs and symptoms of temporomandibular disorders (TMD) were registered by a clinical examination and a questionnaire. The control group comprised 56 age- and gender-matched subjects who were examined at baseline. RESULTS: At the baseline examination, the treatment group had a significantly lower masticatory ability and performance compared with the control group. After treatment, the masticatory ability significantly improved in the treatment group and reached the same level as in the control group. The masticatory performance index increased significantly but was still lower than in the control group. Both the masticatory ability and masticatory performance were affected by the number of occlusal contacts during maximal biting pressure and by the self-estimated overall symptoms of TMD. CONCLUSIONS: Patients with dentofacial deformities, corrected by orthognathic treatment, have a significant positive treatment outcome in respect of masticatory ability and masticatory performance. Furthermore, the occlusion and symptoms of TMD have an impact on both masticatory ability and masticatory performance.
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| 7. |
- Abrahamsson, Cecilia, et al.
(författare)
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TMD before and after correction of dentofacial deformities by orthodontic and orthognathic treatment
- 2013
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Ingår i: International Journal of Oral and Maxillofacial Surgery. - : Elsevier. - 0901-5027 .- 1399-0020. ; 46:6, s. 752-758
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Tidskriftsartikel (refereegranskat)abstract
- Abstract The aims of the study were to investigate the alteration of temporomandibular disorders (TMD) after correction of dentofacial deformities by orthodontic treatment in conjunction with orthognathic surgery; and to compare the frequency of TMD in patients with dentofacial deformities with an age and gender matched control group. TMD were evaluated in 121 consecutive patients (treatment group), referred for orthognathic surgery, by a questionnaire and a clinical examination. 18 months after treatment, 81% of the patients completed a follow-up examination. The control group comprised 56 age and gender matched subjects, of whom 68% presented for follow-up examination. TMD were diagnosed according to research diagnostic criteria for TMD. At baseline examination, the treatment group had a higher frequency of myofascial pain (P=.035) and arthralgia (P=.040) than the control group. At follow-up, the frequencies of myofascial pain, arthralgia and disc displacement had decreased in the treatment group (P=.050, P=.004, P=.041, respectively). The frequency of TMD was comparable in the two groups at follow-up. Patients with dentofacial deformities, corrected by orthodontic treatment in conjunction with orthognathic surgery, seem to have a positive treatment outcome in respect of TMD pain
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| 8. |
- Abrahamsson, Cecilia, et al.
(författare)
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TMD in consecutive patients referred for orthognathic surgery
- 2009
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Ingår i: Angle orthodontist. - : The Angle Orthodontist (EH Angle Education & Research Foundation). - 0003-3219 .- 1945-7103. ; 33:4, s. 201-226
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To answer the question whether temporomandibular disorders (TMD) were more common in a group of individuals referred for orthognathic surgery than in a control group. The null hypothesis was that neither the frequency of signs and symptoms of TMD or diagnosed TMD would differ between the patient group and a control group. MATERIALS AND METHODS: A sample of 121 consecutive patients referred for orthognathic surgery at the Department of Oral Maxillofacial Surgery, Malmö University Hospital, Sweden, was interviewed and examined regarding signs and symptoms of TMD and headaches. A control group was formed by 56 age- and gender-matched individuals attending the Department of Oral Diagnosis, Faculty of Odontology, Malmö University, Sweden, and Public Dental Health Clinic in Oxie, County of Skane, Sweden. TMD diagnoses were used according to Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). RESULTS: The patient group showed more myofascial pain without limited opening, disc displacement with reduction, and arthralgia according to RDC/TMD than the control group. The patient group also had more symptoms and signs of TMD in general. CONCLUSIONS: The null hypothesis was rejected because patients who were to be treated with orthognathic surgery had more signs and symptoms of TMD and higher frequency of diagnosed TMD compared with the matched control group.
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| 9. |
- Berlin, Cecilia, et al.
(författare)
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Keyword mingling workshop : a method for identifying and consolidating industrially perceived needs and requirements of future operators
- 2012
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Ingår i: Swedish Production Symposium, SPS12. - 9789175197524
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Konferensbidrag (refereegranskat)abstract
- Investments into the technology of the future require a firm basis in the needs of production industry. However, gathering, sorting and ranking cross-industrial future needs remains a steep challenge to technology developers. Gathering feedback from just one or a few case companies can result in a biased set of priorities, since feedback from specific industrial sectors may often be highly influenced by their industry- and product-specific challenges. The workshop method presented in this paper resolves this by using a highly interactive "mingling" technique to get participants in a large group workshop (between 15 - 20 people) to answer a specific question. The participants discuss ideas in smaller groups, share their findings to the group at large, co-operatively organize the input from all participants into functional categories, and finally perform a 'ranking' of the results. The outcome is a prioritized list of concerns to focus research efforts on, providing workshop analysts with a finished structure for reporting the results. The method was tested in two workshops within the project "The Operator of the Future" and resulted in plenty of positive feedback from participants, who felt that the input was relevant, well-structured, and easy to agree with due to the consensus categorizing.
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| 10. |
- Berlin, Cecilia, 1981, et al.
(författare)
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Keyword Mingling workshop - a method for identifying and consolidating industrially perceived needs and requirements of future operators
- 2012
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Ingår i: Swedish Production Symposium, SPS12. - 9789175197524
-
Konferensbidrag (refereegranskat)abstract
- Investments into the production technology of the future require a firm basis in the needsof production industry. However, gathering, sorting and ranking cross-industrial futureneeds remains a steep challenge to technology developers. Gathering feedback from justone or a few case companies can result in a biased set of priorities, since feedback fromspecific industrial sectors may often be highly influenced by their industry- and productspecificchallenges. This paper describes a structured method called “Keyword Mingling”that addresses the collection of such feedback in a multi-partner workshop format.The workshop method presented in this paper resolves this by using a highly interactive"mingling" technique to get participants in a large group workshop (between 15 - 20people) to answer a specific question. The participants discuss ideas in smaller groups,share their findings to the group at large, co-operatively organize the input from allparticipants into functional categories, and finally perform a 'ranking' of the results. Theoutcome is a prioritized list of concerns to focus research efforts on, providing workshopanalysts with a finished structure for reporting the results. The method was tested in twoworkshops within the project "The Operator of the Future" and resulted in plenty ofpositive feedback from participants, who felt that the input was relevant, well-structured,and easy to agree with due to the consensus categorizing.
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| 11. |
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| 12. |
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| 13. |
- Grane, Camilla, et al.
(författare)
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The operator of the future – a key to competitive industry in a future information society
- 2012
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Ingår i: Swedish Production Symposium, SPS12. - 9789175197524
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Konferensbidrag (refereegranskat)abstract
- Increased global competition and forthcoming demographic changes is expected for the Swedish industry. The process and manufacturing industry needs to develop solutions that can provide increased flexibility and production efficiency. A key for the future competitiveness is the operator of the future who works closest to the value adding processes. In the project “The operator of the future”, “Framtidsoperatören” in Swedish, the overall aim is to increase the competiveness of Swedish industry by developing an advanced toolbox that meets future needs. In a pre-study, the tasks and needs of the operator of the future were investigated through workshops with 25 representatives from 15 Swedish process and manufacturing industries and system developers. The results had similarities across industries and suggest solutions that support communication, control and constant learning. The tools should be intuitive and situation adapted with use of strengthened senses. These results give the direction for a continued development of a future toolbox. Through a combination of new supporting technologies and new ways of collaboration the operators of the future might find their work more interesting, stimulating, and developing, leading to enhanced competiveness of Swedish industry.
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| 14. |
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| 15. |
- Jakobsson, Hedvig E., et al.
(författare)
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Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by Caesarean section
- 2014
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Ingår i: Gut. - London : BMJ. - 0017-5749 .- 1468-3288. ; 63:4, s. 559-566
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Tidskriftsartikel (refereegranskat)abstract
- important stimuli for immune development, and a reduced microbial exposure as well as caesarean section (CS) has been associated with the development of allergic disease. Here we address how microbiota development in infants is affected by mode of delivery, and relate differences in colonisation patterns to the maturation of a balanced Th1/Th2 immune response. Design The postnatal intestinal colonisation pattern was investigated in 24 infants, born vaginally (15) or by CS (nine). The intestinal microbiota were characterised using pyrosequencing of 16S rRNA genes at 1 week and 1, 3, 6, 12 and 24 months after birth. Venous blood levels of Th1- and Th2-associated chemokines were measured at 6, 12 and 24 months. Results Infants born through CS had lower total microbiota diversity during the first 2 years of life. CS delivered infants also had a lower abundance and diversity of the Bacteroidetes phylum and were less often colonised with the Bacteroidetes phylum. Infants born through CS had significantly lower levels of the Th1-associated chemokines CXCL10 and CXCL11 in blood. Conclusions CS was associated with a lower total microbial diversity, delayed colonisation of the Bacteroidetes phylum and reduced Th1 responses during the first 2 years of life.
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| 16. |
- Langenskiöld, Cecilia, et al.
(författare)
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Determination of blood cell subtype concentrations from frozen whole blood samples using TruCount beads
- 2018
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Ingår i: Cytometry Part B - Clinical Cytometry. - : Wiley. - 1552-4949 .- 1552-4957. ; 94:4, s. 660-666
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Tidskriftsartikel (refereegranskat)abstract
- © 2016 International Clinical Cytometry Society.Background: In many studies it would be advantageous if blood samples could be collected and analyzed using flow cytometry at a later stage. Ideally, sample collection should involve little hands-on time, allow for long-term storage, and minimally influence the samples. Methods: Here we establish a flow cytometry antibody panel that can be used to determine granulocytes, monocytes, and lymphocyte subset concentrations in fresh and frozen whole blood using TruCount technology. Results: The panel can be used on fresh whole-blood samples as well as whole-blood samples that have been frozen after mixing with 10% DMSO. Concentrations in frozen and fresh sample is highly correlated both when frozen within 4 h and the day after collection (r≥0.98), and the estimated concentration in frozen samples was between 91 and 94% of that in fresh samples for all cell types. Conclusion: Using this method whole-blood samples can be frozen using a simple preparation method, and stored long-term before accurate determination of cell concentration. This allows for standardized analysis of the samples at a reference laboratory in multi-center studies.
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| 17. |
- Lawenius, Lina, et al.
(författare)
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Transplantation of gut microbiota from old mice into young healthy mice reduces lean mass but not bone mass
- 2023
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Ingår i: Gut Microbes. - 1949-0976. ; 15:1
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Tidskriftsartikel (refereegranskat)abstract
- Aging is associated with low bone and lean mass as well as alterations in the gut microbiota (GM). In this study, we determined whether the reduced bone mass and relative lean mass observed in old mice could be transferred to healthy young mice by GM transplantation (GMT). GM from old (21-month-old) and young adult (5-month-old) donors was used to colonize germ-free (GF) mice in three separate studies involving still growing 5- or 11-week-old recipients and 17-week-old recipients with minimal bone growth. The GM of the recipient mice was similar to that of the donors, demonstrating successful GMT. GM from old mice did not have statistically significant effects on bone mass or bone strength, but significantly reduced the lean mass percentage of still growing recipient mice when compared with recipients of GM from young adult mice. The levels of propionate in the cecum of mice receiving old donor GM were significantly lower than those in mice receiving young adult donor GM. Bacteroides ovatus was enriched in the microbiota of recipient mice harboring GM from young adult donors. The presence of B. ovatus was not only significantly associated with high lean mass percentage in mice, but also with lean mass adjusted for fat mass in the large human HUNT cohort. In conclusion, GM from old mice reduces lean mass percentage but not bone mass in young, healthy, still growing recipient mice. Future studies are warranted to determine whether GM from young mice improves the musculoskeletal phenotype of frail elderly recipient mice.
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| 18. |
- Lindholm, Maria, et al.
(författare)
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Färdplan för citylogistik : Godstransporter i urbana områden
- 2014
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Denna rapport är indelad i fem avsnitt. Inledningsvis presenteras problem och målbild. Dessa kapitel syftar till att skapa en bild av den övergripande situationen, förstå varför det är viktigt att arbeta med frågan citylogistik och förklara de mål som satts upp. Därefter presenteras nuläge och förutsättningar. Detta ger en bild av hur situationen ser ut i Sverige idag. Här presenteras även de innovationsdomäner som hanteras i rapporten och aktiviteter sorteras in inom. Milstolpar och tänkbara koncept presenterar inledningsvis en bruttolista på aktiviteter som krävs för att nå målen, men ger sedan en inriktning i form av nästa steg av vilka av dessa aktiviteter som bör prioriteras i nuläget. Förslag på demonstrationsprojekt presenteras följt av en koppling till omvärlden (EU). Färdplanen avslutas med en SWOT analys och tänkbar påverkan samt två appendix: Arbetsprocessen kring färdplanens framtagande, samt Aktivitetslista.
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| 19. |
- Lindskov, Cecilia
(författare)
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Family centre practice and modernity : a qualitative study from Sweden
- 2010
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Family centres have become a common institution to promote health and wellbeingamong young children (0-6 years of age) and their parents in Sweden. Thecore of the work is usually based on both maternal and child health care, a preschooland social services, all located under the same roof in the local community.The family centre in this study, known as the "Family House", was the firstof its type to be built in the city of Kristianstad, Sweden.The overall aim of the thesis was to understand family centre practice throughprofessionals' and parents' perceptions of the Family House and its relationship to modernity.The study employed a qualitative design using phenomenography as method tocapture people's perceptions of the practice. The research also drew on the approachof action research, where participants and researchers co-generateknowledge through collaborative communicative processes. Data was generatedfrom semi-structured interviews conducted with nineteen professionals andsixteen individual parents. Dialogue sessions with the professionals of the studyhave been held in order that they and the researcher could enter into a dialoguebased on the findings of the interviews. Data was consequently also generatedfrom these meetings.The way the professionals perceived the practice of the Family House fell intothree categories, namely, as a professional service, the provision of an informalmeeting place for professionals and families with young children or as a broadcommunity-based centre. Parents' perceptions fell into four categories; as aprofessional reception to obtain expert guidance and support, a study circle andliving room to informally share experiences and socialising, and a playgroundfor children where children could interact and learn social skills.One core finding of this thesis is that family centre practice for those involvedcontained a balancing act between simple modern expertise to control the futureand late modern opportunities for self-realisation and reflexivity.Parents and professionals shared the responsibility for children's well-being andthe distinction between private and public was blurred since parents used theHouse as a social arena for developing personal relations. It was also an arenafor integration between Swedes and immigrants based on engagement for bothcultural diversity and similarity.
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| 20. |
- Lundmark, Felix, 1994-
(författare)
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Framtidens arbete i den digitala och gröna omställningen : Förändring och stabilisering
- 2024
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This dissertation focuses on the construction of future steel work and work environment in relation to the ongoing digital and green transitions. The transitions include a clear focus on technology and has so far been lacking a focus on work. Future steel work run the risk of being forgotten in the transition processes, or only indirectly addressed. The purpose is therefore to investigate how new technology, based on the transitions, is constructed in the steel industry and how this relates to the development of the future work and work environment. This refers to the construction that takes place in the form of the process by which technology is constructed by actors, and to the construction that takes place in the form of descriptions and interpretations of new technology, through which it is given meaning.The dissertation is based on a sociotechnical tradition but utilizes theories from science and technology studies on the social construction of technology to understand how actors participate and contribute to the development of technology. The empirical data has been produced mainly from semi-structured interviews with managers, project managers, and workers with union roles, which through thematic analysis has resulted in six different main themes: work environment and safety, rationalization, competence, environment, influence, and gender equality. The empirical material also includes documents and empirical data produced during workplace visits, meetings, etc. in the shape of a logbook.The results demonstrate that work is largely absent in the descriptions of new technology. New technology is primarily interpreted and described as rationalizing the production process or being linked directly to fossil-free steelmaking. At the same time, descriptions of new technology in relation to work indicate that new technology is generally regarded as the solution to existing problems, primarily described as physical. New technology being viewed as the solution to today's problems has also proven to be the case for the environmental challenges, where fossil-free steelmaking is broadly considered to be the solution. The understanding of fossil-free steelmaking in relation to work is reduced to an understanding of the possibility of fewer jobs in the future. Similarly, new technology is seen as contributing to addressing challenges of gender equality, primarily expressed interms of eliminating heavy work tasks and thus being able to influence the gender distribution at the company. On the other hand, new technology is expected to increase the skills requirement for workers that are faced with working alongside a more technologically advanced production system.From a process perspective, future work can be seen as constructed through investment projects that gradually stabilize the future work and work environment, from social constructions to concrete work tasks. Future work and work environments are stabilized by methods where primarily the physical dimension of the work environment is prioritized, in a process where the most intense stabilization take place at an early stage. The opportunities to create good future work and work environments are reduced to the degrees of freedom and resources that remain, in relation to the project participants' competence regarding work environment and the workers' ability to represent the interests of their respective groups. The consequence is that the process relies on user participation, which can be characterized to include information to workers, worker input and difficulties in recruiting workers as project participants.The dissertation concludes that the good future steel work is left out of the construction of new technology by the combination of a belief in new technology as the solution to today's problems, and a process that mainly focuses on one of the three dimensions of the work environment. The exclusion of the good work does not mean that work is not affected within the transitions, but rather that the construction of the future work takes place whether it is intentionally in the direction of good work, or indirectly by means of other purposes.
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| 21. |
- Shmarina, Elena
(författare)
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Oral health-related salutogenic factors : reviewing factors promoting oral health in older people and exploring dental professionals' perspective
- 2023
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The overarching aims of this thesis were to study oral health-related salutogenic factors among older people and explore dental professionals’ perceptions of their role in the practice of oral health promotion.Study I was an integrative review describing salutogenic factors reportedly associated with oral health and oral health-related quality of life in older people. A framework for identifying salutogenic factors, combining two theories of health, was developed. 58 papers were included in the review and 77 salutogenic factors were identified. However, there is a lack of studies with specific reference to salutogenic factors among older people.Study II was a cross-sectional study based on data for patients 60 years or older derived from a previous population-based epidemiological study. Several significant associations between outcome variables and salutogenic factors were identified. Of those, 13 previously unreported salutogenic factors could be added to the framework developed in Study I.Studies III and IV were qualitative interview studies using in-depth interviewsfor data collection and qualitative content analysis methodology for data analysis.Study III focused on exploring salutogenic factors related to oral health in twelve orally healthy patients 75 years or older. The findings highlighted the importance of patients’ internal resources, dental professionals, family, and society in supporting and reinforcing lifelong oral health.Study IV focused on exploring dental professionals’ perceptions of their role in the practice of oral health promotion and included eleven dentists and dental hygienists. The participants perceived promotion of oral health to be an important aspect of their professional role. They aspired to patient participation in the decision-making process and educational activities, as well as practicing and evaluating skills development.In conclusion, there is a need for consistency in definition of outcomes measures and hypothesis-driven research within salutogenic research in oral health field. The large number of salutogenic factors found supporting oral health among older people indicates the complexity of salutogenesis and the need for robust analyzing tools. Combining two theories of health was useful for exploring salutogenic factors related to oral health and for providing a plain overview of areas lacking knowledge, which in turn can facilitate the generation of hypotheses and therefore relevant salutogenic research.This combination could contribute to a more balanced image of factors influencing oral health, including dental professionals’ roles, and help identify critical next steps in determining priorities and allocating resources promoting good oral health in individuals and populations. Moreover, oral health-related salutogenic factors identified in the qualitative studies; i.e., categories, merit further exploration in quantitative research.
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| 22. |
- Springett, Jane, 1952-, et al.
(författare)
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Annual report 2004
- 2005
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Rapport (övrigt vetenskapligt/konstnärligt)
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| 23. |
- Springett, Jane, et al.
(författare)
-
Annual report 2004
- 2005
-
Bok (övrigt vetenskapligt/konstnärligt)
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| 24. |
- Springett, Jane, 1952-, et al.
(författare)
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Närsjukvård : bakgrund, erfarenheter och pilotstudie
- 2005
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Närsjukvård är ett centralt begrepp i ett förändringsarbete som för genomförs i nordöstra Skåne för att utveckla hälso- och sjukvårdsväsendet. Det ingår därmed som en av de centrala delarna av Region Skånes vision om hälso- och sjukvård: Skånsk livskraft – vård och hälsa. Syftet med denna rapport är att ge en bakgrund till begreppet (Del A) och att presentera en del preliminära rön beträffande hur olika aktörer i nordöstra Skåne uppfattar begreppet (Del B). Del A ger en översikt kring ursprunget till begreppet Närsjukvård inom ramen för de förändringar i hälso- och sjukvården som sker i Sverige i stort. Den beskriver sedan vilka slags förändringar som har planerats på politisk nivå och som nu håller på att genomföras under detta paraplybegrepp, nationellt, regionalt och lokalt. För detta syfte används statliga dokument och publicerade utvärderingsstudier i stor utsträckning som källmaterial. Denna del ska därför inte ses som en heltäckande översikt. Del B inriktas på att belysa hur långt förverkligandet av idén om Närsjukvård har kommit inom regionen. Avsnittet är en kartläggning av olika aktörers förståelse av Närsjukvård i den nordöstra delen av Region Skåne. Forskningsfrågorna inriktades på hur folk pratade om Närsjukvård, det vill säga på hur de förstod och använde begreppet.
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| 25. |
- Springett, Jane, et al.
(författare)
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Närsjukvård : bakgrund, erfarenheter och pilotstudie
- 2005
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Närsjukvård är ett centralt begrepp i ett förändringsarbete som för genomförs i nordöstra Skåne för att utveckla hälso- och sjukvårdsväsendet. Det ingår därmed som en av de centrala delarna av Region Skånes vision om hälso- och sjukvård: Skånsk livskraft – vård och hälsa. Syftet med denna rapport är att ge en bakgrund till begreppet (Del A) och att presentera en del preliminära rön beträffande hur olika aktörer i nordöstra Skåne uppfattar begreppet (Del B). Del A ger en översikt kring ursprunget till begreppet Närsjukvård inom ramen för de förändringar i hälso- och sjukvården som sker i Sverige i stort. Den beskriver sedan vilka slags förändringar som har planerats på politisk nivå och som nu håller på att genomföras under detta paraplybegrepp, nationellt, regionalt och lokalt. För detta syfte används statliga dokument och publicerade utvärderingsstudier i stor utsträckning som källmaterial. Denna del ska därför inte ses som en heltäckande översikt. Del B inriktas på att belysa hur långt förverkligandet av idén om Närsjukvård har kommit inom regionen. Avsnittet är en kartläggning av olika aktörers förståelse av Närsjukvård i den nordöstra delen av Region Skåne. Forskningsfrågorna inriktades på hur folk pratade om Närsjukvård, det vill säga på hur de förstod och använde begreppet.
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| 26. |
- Stratmann, Svea, 1989-, et al.
(författare)
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Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children
- 2023
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Ingår i: Leukemia. - : Springer Science and Business Media LLC. - 0887-6924 .- 1476-5551. ; 37:3, s. 550-559
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Tidskriftsartikel (refereegranskat)abstract
- Despite improvement of current treatment strategies and novel targeted drugs, relapse and treatment resistance largely determine the outcome for acute myeloid leukemia (AML) patients. To identify the underlying molecular characteristics, numerous studies have been aimed to decipher the genomic- and transcriptomic landscape of AML. Nevertheless, further molecular changes allowing malignant cells to escape treatment remain to be elucidated. Mass spectrometry is a powerful tool enabling detailed insights into proteomic changes that could explain AML relapse and resistance. Here, we investigated AML samples from 47 adult and 22 pediatric patients at serial time-points during disease progression using mass spectrometry-based in-depth proteomics. We show that the proteomic profile at relapse is enriched for mitochondrial ribosomal proteins and subunits of the respiratory chain complex, indicative of reprogrammed energy metabolism from diagnosis to relapse. Further, higher levels of granzymes and lower levels of the anti-inflammatory protein CR1/CD35 suggest an inflammatory signature promoting disease progression. Finally, through a proteogenomic approach, we detected novel peptides, which present a promising repertoire in the search for biomarkers and tumor-specific druggable targets. Altogether, this study highlights the importance of proteomic studies in holistic approaches to improve treatment and survival of AML patients.
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| 27. |
- Wästerlid, Cecilia, et al.
(författare)
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The Table & Swirl Method: A Quick Visualization Methodfor Aspects of Circular Material Streams
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This document describes the Table & Swirl method, which is a quick visualization method for aspects of circular material streams. Use the method to structure and visualize information to understand and share aspects of material streams in a circular economy. It is a time efficient way to start interesting discussions on any topic related to a circular material stream. The method is built around the Table, a tool to in a structured way gather information and the Swirl, which provides quick visualization.The feedback from our test workshops and end-users were: • ”An eye opener!” • ”First, I thought the model was too simple, then I realized how quickly we got into interesting discussions.”This method was developed in the year 2023 by the Research Institute of Sweden (RISE) and Luleå University of Technology (LTU) in the joint project “Feasibility study: Five circular material streams for batteries“, which was financed by Energimyndigheten, the Swedish Energy Agency.
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