| 1. |
- Abrahamsson, Kajsa H., 1956, et al.
(författare)
-
Altered expectations on dental implant therapy; views of patients referred for treatment of peri-implantitis
- 2017
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 28:4, s. 437-442
-
Tidskriftsartikel (refereegranskat)abstract
- © 2016 John Wiley & Sons A/S.Aim: The aim was to explore patients' reactions on being diagnosed with peri-implantitis, their opinions on dental implant therapy and expectations on treatment of the disease. Material and methods: The study subjects were patients referred to a specialist clinic for treatment of peri-implantitis. The method of grounded theory was used in collecting and analyzing data. Audiotaped, thematized open-ended interviews were conducted. The interviews were transcribed verbatim and consecutively analyzed in hierarchical coding processes that continued until saturation was met (n = 15). Results: In the analysis, a conceptual model was generated that illuminated a process among patients. From having very high initial expectations on dental implant therapy as a permanent solution of oral/dental problems, patients realized that dental implants, such as teeth, require continuous care and that there is no guarantee for that dental implants provides a treatment alternative free from future problems. The core concept of the model "altered expectations on dental implant therapy" was composed of three main categories: "initial expectations on dental implant therapy and living with dental implants", "being referred to periodontist and become diagnosed with peri-implantitis" and "investing again in an expensive therapy with no guarantee for the future". Conclusion: Patients may have unrealistically high expectations on dental implant therapy. The results illuminate the importance of patient-centered communication in dentistry and that treatment decisions should be based not only on professional expertise but also on expectations, abilities, wishes and life circumstances of the individual patient.
|
|
| 2. |
- Dimenäs, Sandra L., 1989, et al.
(författare)
-
A person-centred, theory-based, behavioural intervention programme for improved oral hygiene in adolescents: A randomized clinical field study
- 2022
-
Ingår i: Journal of Clinical Periodontology. - : Wiley. - 0303-6979 .- 1600-051X. ; 49:4, s. 237-387
-
Tidskriftsartikel (refereegranskat)abstract
- Aim: To test the effectiveness of a person-centred and theory-based educational intervention to increase adolescents′ adherence to adequate oral hygiene behaviour, that is, self-performed periodontal infection control. Materials and Methods: Data were derived from a prospective, multi-centred, two-arm, quasi-randomized field study in which treatment was performed by dental hygienists (DHs) within the Public Dental Service, Västra Götaland, Sweden. Adolescents with poor oral hygiene conditions were invited to participate. The test intervention was based on cognitive behavioural theory and principles, and the DHs used a collaborative communicative approach, inspired by motivational interviewing. The control intervention consisted of conventional information/instruction. Clinical assessments and oral hygiene behaviours were evaluated at 6months. Results: Three-hundred and twelve adolescents were enrolled, of whom 274 followed the treatment to 6-month follow-up. There were significant improvements in gingival bleeding and plaque scores for both treatment groups at 6months, with significantly greater improvements in the test group. Adolescents in the test group brushed their teeth and used interdental cleaning aids more frequently compared to participants in the control group at 6months. Conclusion: A person-centred and theory-based oral health education programme ismore effective than conventional oral health education in improving adolescents' oral hygiene behaviour and periodontal infection control. ClinicalTrials.gov (NCT02906098). © 2022 The Authors. Journal of Clinical Periodontology published by John Wiley & Sons Ltd.
|
|
| 3. |
- Veltri, Mario, et al.
(författare)
-
Three-Dimensional buccal bone anatomy and aesthetic outcome of single dental implants replacing maxillary incisors
- 2016
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161. ; 27:8, s. 956-963
-
Tidskriftsartikel (refereegranskat)abstract
- ObjectivesThis case series investigated by means of CBCT, buccal bone three-dimensional anatomy at delayed, two-stage implants in the maxillary incisal tooth region. Moreover, the relation between buccal bone anatomy and soft tissue aesthetics was assessed. Material and methodsTwelve implants were analysed after on average 8.9years in function. Baseline and re-evaluation photographs were assessed using the pink aesthetic score (PES). Marginal bone changes were measured from intraoral X-rays. The buccal bone volume associated with the implant and the implant surface not covered by visible buccal bone was computed on CBCT data sets. Buccal bone thickness and level were assessed, as well as the thickness of the crest distally and mesially of the implant. Changes in soft tissue forms and correlation between aesthetics and bone anatomy were calculated by nonparametric statistics. ResultsBuccal bone level was located 3.8mm apical of the implant shoulder, and none of the implants had complete bone coverage. Buccal bone volume was 144.3mm(3), and 4.29mm(3) in the more coronal 2mm portion. PES did not differ at re-evaluation (9.7) and baseline (9.2). PES was directly correlated with crestal thickness mesially and distally of the implant shoulder. No other significant correlations were observed between bone anatomy and PES or buccal peri-implant health. Marginal bone gain over time was associated with greater coronal bone volume buccally and with greater buccal and marginal bone thickness, while loss was related to less or no bone. ConclusionsWithin present limitations, acceptable and stable aesthetics are not jeopardized by a thin or missing buccal bone.
|
|
| 4. |
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
- Abrahamsson, Ingemar, 1953, et al.
(författare)
-
Early bone formation adjacent to rough and turned endosseous implant surfaces. An experimental study in the dog
- 2004
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 15:4, s. 381-92
-
Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To validate a proposed model (Berglundh et al. 2003) and to evaluate the rate and degree of osseointegration at turned (T) and sand blasted and acid etched (SLA) implant surfaces during early phases of healing. MATERIAL AND METHODS: The devices used for the study of early healing had a geometry that corresponded to that of a solid screw implant with either a SLA or a T surface configuration. A circumferential trough had been prepared within the thread region (intra-osseous portion) that established a geometrically well-defined wound chamber. Twenty Labrador dogs received totally 160 experimental devices to allow the evaluation of healing between 2 h and 12 weeks. Both ground and decalcified sections were prepared from mesial/distal and buccal/lingual device sites. Histometric and morphometric analyses of the ground sections and morphometric analysis of the tissue components in decalcified sections were performed. RESULTS: The ground sections provided an overview of the various phases of tissue formation, while the decalcified, thin sections enabled a more detailed study of events involved in bone tissue modeling and remodeling for both SLA and T surfaces. The initially empty wound chamber became occupied with a coagulum and a granulation tissue that was replaced by a provisional matrix. The process of bone formation started already during the first week. The newly formed bone present at the lateral border of the cut bony bed appeared to be continuous with the parent bone, but on the SLA surface woven bone was also found at a distance from the parent bone. Parallel-fibered and/or lamellar bone as well as bone marrow replaced this primary bone after 4 weeks. In the SLA chambers, more bone-to-device contact, more initial woven bone and earlier lamellar bone formation was found than in the T chambers. CONCLUSION: Osseointegration represents a dynamic process both during its establishment and its maintenance. While healing showed similar characteristics with resorptive and appositional events for both SLA and T surfaces, the rate and degree of osseointegration were superior for the SLA compared with the T chambers.
|
|
| 8. |
- Abrahamsson, Ingemar, 1953, et al.
(författare)
-
Early bone healing to implants with different surface characteristics. A pre-clinical in vivo study
- 2023
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 34:4, s. 312-9
-
Tidskriftsartikel (refereegranskat)abstract
- AimTo examine early bone healing around implants with non-modified and modified surfaces. Material & MethodsFour implants with 4 different surface characteristics were installed in one side of the mandible following tooth extraction in 6 dogs. Implants in group A had a non-modified, turned surface, while implants in group B had a surface modification consisting of TiO-blasting and sequential acid-etching in oxalic and hydrofluoric acid. The surface modification of implants in group C was confined to sequential acid-etching in oxalic and hydrofluoric acid and Group D implants had a surface modification of TiO-blasting and acid-etching in hydrofluoric acid. The implant installation procedures were repeated in the opposite side of the mandible 4 weeks later. Biopsies were obtained and prepared for histological analysis 2 weeks later. ResultsB and C implants had a higher degree of bone-to-implant contact (BIC%) than A and D implants at 2 weeks of healing. At 6 weeks of healing, the BIC% was higher at B than at A, C and D implants, and higher at C implants than at A implants. The amount of newly formed bone in contact with the implant within the defect area at 2 weeks was higher at implants with modified surfaces (groups B, C and D) than at implants with a non-modified surface (group A). Corresponding results at 6 weeks were superior at B implants. ConclusionIt is suggested that an implant surface modification with acid-etching in oxalic and hydrofluoric acid promotes early formation of bone-to-implant contact.
|
|
| 9. |
|
|
| 10. |
- Abrahamsson, Ingemar, 1953, et al.
(författare)
-
Healing at fluoride-modified implants placed in wide marginal defects: an experimental study in dogs.
- 2008
-
Ingår i: Clinical oral implants research. - : Wiley. - 0905-7161 .- 1600-0501. ; 19:2, s. 153-9
-
Tidskriftsartikel (refereegranskat)abstract
- Objective: To study the healing at fluoride-modified implants placed in wide circumferential defects. Material and methods: Six mongrel dogs were used. The mandibular premolars and first molars were extracted. Three months later four implants were placed in one side of the mandible of each dog. The control implants (MicroThread(trade mark)) had a TiOblast surface, while the test implants (OsseoSpeed(trade mark)) had a fluoride-modified surface. Two implants of each type were placed. The marginal 50% of the prepared canal was widened using step drills. Following installation a 1 mm wide gap occurred between the implant surface and the bone wall in the defect. All implants were submerged. The installation procedure was repeated in the opposite side of the mandible 4 weeks after the first implant surgery. Two weeks later the animals were euthanized and block biopsies containing the implant and surrounding tissues were prepared for histological analysis. Results: The histological analysis revealed that a significantly larger area of osseointegration was established within the defect at fluoride-modified implants than at implants with a TiOblast surface after 6 weeks of healing. Further, the degree of bone-to-implant contact within the defect area was larger at fluoride-modified implants than at the TiOblast implants. Conclusion: It is suggested that the fluoride-modified implant surface promotes bone formation and osseointegration.
|
|
| 11. |
- Abrahamsson, Ingemar, 1953, et al.
(författare)
-
Healing at Implants Placed in an Alveolar Ridge with a Sloped Configuration: An Experimental Study in Dogs.
- 2014
-
Ingår i: Clinical implant dentistry and related research. - : Wiley. - 1708-8208 .- 1523-0899. ; 16:1, s. 62-69
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose: To study healing around implants placed in an alveolar ridge with a sloped lingual-buccal configuration. Materials and Methods: Six Labrador dogs were used. Buccal bone defects were prepared in the mandible after extraction of premolars. Three months later, two test implants with a sloped marginal design and two control implants were placed in the chronic defect area with a sloped lingual-buccal configuration of each premolar region. The test implants were placed in such a way that the buccal margin of the implant coincided with the buccal bone crest. The lingual margin of the control implants was placed to a similar depth as the lingual margin of the test implants. Abutments were connected to the implants in the right mandibular premolar region and flaps were sutured around the neck of the abutments. In the left side of the mandible, cover screws were placed and the flaps were sutured to cover the implants. Biopsies were obtained 4 months later and prepared for histological examination. Results: It was demonstrated that healing around implants placed in an alveolar ridge with a sloped lingual-buccal configuration resulted in the preservation of a vertical discrepancy between the lingual and buccal marginal bone levels around implants with either a regular cylindrical outline or a modified marginal portion that matched the slope of the alveolar ridge. Conclusion: As the marginal buccal portion of the control implants with a regular design had no bone support, it is suggested that implants with a modified marginal portion may be considered in recipient sites with a sloped lingual-buccal configuration.
|
|
| 12. |
|
|
| 13. |
- Abrahamsson, Ingemar, 1953, et al.
(författare)
-
Influence of implant geometry and osteotomy design on early bone healing: A pre-clinical in vivo study
- 2021
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 32:10, s. 1190-1199
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives To analyze the early stages of osseointegration around implants with different geometry following installation in sites using different osteotomy protocols. Materials and methods Two types of implants were installed using regular or modified (reduced diameter) osteotomy protocols in mandibular premolar/molar regions following tooth extraction in six dogs. Three implant site categories were created: Reference (A implant and regular osteotomy), Test-1 (B implant and regular osteotomy), and Test-2 (B implant and modified osteotomy). Implant installation procedures were repeated after 4 and 6 weeks. The insertion torque (ITQ) was measured during implant installation and resonance frequency analysis providing implant stability quotient (ISQ) values was performed following implant installation and once every week during the course of the study. Biopsies were obtained immediately after the 3rd installation procedure and prepared for histological analysis. Results The modified osteotomy protocol created a higher insertion torque (ITQ). The analysis also revealed a correlation between insertion torque at implant installation and radiographic bone loss after 6 weeks of healing. The decline in ISQ values during healing was more pronounced at Test-2 than other sites. While the degree of bone-to-implant contact (BIC%) in the marginal area was similar in test and reference sites at 6 weeks of healing, Test-2 implants presented with a significantly higher BIC% in the mid and apical areas than Test-1 implants. Conclusions It is suggested that placement of implants in undersized osteotomy sites will result in an increased remodeling of the cortical bone during the early healing process.
|
|
| 14. |
- Abrahamsson, Ingemar, 1953, et al.
(författare)
-
Peri-implant hard and soft tissue integration to dental implants made of titanium and gold.
- 2007
-
Ingår i: Clinical oral implants research. - : Wiley. - 0905-7161 .- 1600-0501. ; 18:3, s. 269-74
-
Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: The aim of the study is to compare the peri-implant hard and soft tissue integration around dental implants made of commercially pure (c.p.) titanium or a gold alloy but with the same shape and surface roughness. MATERIAL AND METHODS: In four beagle dogs, all mandibular premolars were extracted. Three months later, four experimental non-submerged implants were placed in each edentulous premolar region. Each implant comprised three different zones: zone A (coronal), zone B (central) and zone C (apical). Each zone was made of either c.p. titanium or a gold alloy. Four different combinations of metal and zone were used. A plaque control program was initiated and 6 months later, the animals were sacrificed and biopsies were obtained. The biopsies including the implant and the surrounding tissues were processed for ground sectioning. RESULTS: The height of the peri-implant mucosa and the length of the barrier epithelium were similar at the four experimental sites. The marginal bone level in the different metal combinations was located between 4.5 and 4.8 mm apical of the implant rim. The percent of mineralized bone that was in direct contact with the implant surface (BIC%) was consistently greater in the marginal than in the apical portion of the implants. The BIC% for the marginal and apical zone were consistently greater for implant portions made of titanium than for portions made of gold alloy (zone B: 42.7% vs. 36.5%, zone C: 33.2% vs. 19%). CONCLUSIONS: Osseointegration was achieved to surfaces made of both c.p. titanium and a gold alloy. BIC% was higher at titanium than at gold surfaces. Moreover, the peri-implant soft tissue dimensions were not influenced by the metal used in the 'marginal' zone of the implant.
|
|
| 15. |
|
|
| 16. |
- Abrahamsson, Ingemar, 1953, et al.
(författare)
-
Probe penetration in periodontal and peri-implant tissues. An experimental study in the beagle dog.
- 2006
-
Ingår i: Clinical oral implants research. - : Wiley. - 0905-7161 .- 1600-0501. ; 17:6, s. 601-5
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Today, periodontal probing is the best diagnostic tool to assess the health status and attachment level of periodontal tissues. There are, however, doubts as to whether the same method could be used for implants. Experiments comparing peri-implant and periodontal probing provide conflicting results. The impact and interpretation of peri-implant probing are still not sufficiently known. PURPOSE: The purpose of the present study was to further analyze the histological level of probe penetration in healthy periodontal and peri-implant tissues. MATERIAL AND METHODS: In four beagle dogs, all mandibular premolars were extracted. Three months later, four experimental non-submerged implants were placed in each edentulous premolar region. Six months later, probing depth was determined at the buccal aspect at two of the implants and at the bilateral first mandibular molars. A pressure-controlled probe with a diameter of 0.4 mm and 0.2 N probing force was used. Following the probing depth assessment, a metal periodontal probe tip was inserted into the previously measured depth and attached to the implants and teeth using a composite material. Block biopsies were obtained and prepared for histometric examinations. RESULTS: The findings showed that probing resulted in similar probe extension at implants and teeth, that the probe extension corresponded to the extension of the barrier epithelium and that the distance between the probe tip and the bone was about 1 mm in both peri-implant and periodontal tissues. CONCLUSIONS: This experiment showed that under healthy conditions, the probe tip penetration in the soft tissues at teeth and implants is similar when a probing force of 0.2 N is used. Probing around implants using a moderate force is a valuable diagnostic tool in the maintenance of implant patients.
|
|
| 17. |
|
|
| 18. |
|
|
| 19. |
|
|
| 20. |
|
|
| 21. |
|
|
| 22. |
|
|
| 23. |
- Abrahamsson, Ingemar, 1953, et al.
(författare)
-
Tissue characteristics at microthreaded implants: an experimental study in dogs.
- 2006
-
Ingår i: Clinical implant dentistry and related research. - : Wiley. - 1523-0899 .- 1708-8208. ; 8:3, s. 107-13
-
Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: The aim of the present study was to analyze bone tissue reactions at implants with and without a microthread configuration. MATERIALS AND METHODS: In six beagle dogs, one test and two control implants were installed in one side of the mandible. While both implant types had a similar dimension and surface roughness, the test implants were designed with a microthread configuration in the marginal portion. Abutment connection was performed after 3 months. Another 3 months later, fixed partial dentures (FPDs) were cemented to the maxillary canine and premolars and FPDs were connected to the implants in the mandible. Ten months later, the animals were sacrificed and biopsies from each implant region were processed for histological analysis. Radiographs were obtained at implant placement after FPD connection and at the termination of the experiment. RESULTS: The radiographic examination revealed that the marginal bone level was well preserved at both test and control implants during the entire 16-month period. The degree of bone-implant contact within the marginal portion of the implants was significantly higher at the test (microthread) implants (81.8%) than at the control implants (72.8%). CONCLUSIONS: It was suggested that the microthread configuration offered improved conditions for osseointegration.
|
|
| 24. |
|
|
| 25. |
|
|
| 26. |
|
|
| 27. |
|
|
| 28. |
- Albouy, Jean-Pierre, 1969, et al.
(författare)
-
Spontaneous progression of peri-implantitis at different types of implants. An experimental study in dogs. I: clinical and radiographic observations.
- 2008
-
Ingår i: Clinical oral implants research. - : Wiley. - 1600-0501 .- 0905-7161. ; 19:10, s. 997-1002
-
Tidskriftsartikel (refereegranskat)abstract
- AIM: The aim of the present study was to analyze tissue reactions to plaque formation following ligature removal at commercially available implants exposed to experimental peri-implantitis. Material and methods: Six Labrador dogs about 1 year old were used. All mandibular premolars and the three anterior premolars in both sides of the maxilla were extracted. After 3 months four implants representing four different implant systems with different surface characteristics--implant group A (turned), B (TiOblast), C (sandblasted acid-etched; SLA) and D (TiUnite)--were placed in a randomized order in the right side of the mandible. Three months after implant installation experimental peri-implantitis was initiated by placement of ligatures in a submarginal position and plaque accumulation. At week 12, when about 40-50% of the supporting bone was lost, the ligatures were removed. During the subsequent 24-week period plaque accumulation continued. Radiographic and clinical examinations were performed during the 'active breakdown' period (plaque accumulation and ligatures) and the plaque accumulation period after ligature removal. The experiment was terminated at week 36. Results: The bone loss that took place during the 'active breakdown' period varied between 3.5 and 4.6 mm. The additional bone loss that occurred during the plaque accumulation period after ligature removal was 1.84 (A), 1.72 (B), 1.55 (C) and 2.78 mm (D). Conclusion: Spontaneous progression of experimentally induced peri-implantitis occurred at implants with different geometry and surface characteristics. Progression was most pronounced at implants of type D (TiUnite surface).
|
|
| 29. |
- Almohandes, Ahmed, et al.
(författare)
-
Accuracy of bone-level assessments following reconstructive surgical treatment of experimental peri-implantitis
- 2022
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 33:4, s. 433-440
-
Tidskriftsartikel (refereegranskat)abstract
- Aims The purpose of this study was to evaluate the accuracy of bone-level assessments using either cone-beam computed tomography (CBCT), intra-oral peri-apical (PA) radiographs or histology following reconstructive treatment of experimental peri-implantitis. Materials and Methods Six Labrador dogs were used. Experimental peri-implantitis was induced 3 months after implant placement. Surgical treatment of peri-implantitis was performed and peri-implant defects were allocated to one of four treatment categories; no augmentation, bone graft materials with or without a barrier membrane. Six months later, intra-oral PA radiographs and block biopsies from all implants sites were obtained. Marginal bone levels (MBLs) were measured using PA radiographs, CBCT and histology. Results Significant correlations of MBL assessments were observed between the three methods. The measurements in PA radiographs consistently resulted in an overestimation of the bone level of about 0.3-0.4 mm. The agreement between the methods was not influenced by the use of bone substitute materials in the management of the osseous defects. Conclusions Although MBL assessments obtained from PA radiographs showed an overestimation compared to MBL assessments on corresponding CBCT images and histological sections, PA radiographs can be considered a reliable technique for peri-implant bone-level evaluations following reconstructive surgical therapy of experimental peri-implantitis.
|
|
| 30. |
- Almohandes, Ahmed, et al.
(författare)
-
Effect of biofilm formation on implant abutments with an anti-bacterial coating: A pre-clinical in vivo study
- 2021
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 32:6, s. 756-766
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives To analyse the long-term effect of plaque formation on implant abutments with an antibacterial coating and the ensuing host response in peri-implant tissues. Materials and methods Four implants were installed in each mandibular premolar region following tooth extraction in six dogs. Three months later, two test abutments with a titanium-bismuth-gallium (Ti-Bi-Ga) coating and two control titanium abutments were connected to the implants on each side of the mandible. After 2 months, ligatures were placed around the implants in one side of the mandible and plaque formation was allowed until the end of the experiment. The ligatures were removed after 4 weeks. Radiographs and microbiological samples were obtained from each implant site during the plaque formation period. Biopsies were obtained 8 months after abutment connection and prepared for histological analysis. Results The analysis did not reveal any statistically significant differences in bone loss, bacterial growth and size of inflammatory lesions between implant units with and without the Ti-Bi-Ga coating. Implant sites exposed to the short period of ligature-induced breakdown demonstrated more pronounced bone loss and bacterial growth than non-ligature sites. Conclusions It is suggested that a Ti-Bi-Ga coating does not prevent biofilm formation on the implant device and does not influence the ensuing host response in the adjacent peri-implant mucosa.
|
|
| 31. |
- Almohandes, Ahmed, et al.
(författare)
-
Re-osseointegration following reconstructive surgical therapy of experimental peri-implantitis. A pre-clinical in vivo study
- 2019
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 30:5, s. 447-456
-
Tidskriftsartikel (refereegranskat)abstract
- Objective To evaluate the effect of bone substitute materials on hard and soft tissue healing in reconstructive surgical therapy of experimental peri-implantitis at implants with different surface characteristics. Material and methods Six female, Labrador dogs were used. 3 months after tooth extraction, four implants with two different surface characteristics (A and B) were installed on each side of the mandible. Experimental peri-implantitis was induced 3 months later. During surgical treatment of peri-implantitis, the implants were cleaned with curettes and cotton pellets soaked in saline. The implant sites were allocated to one of four treatment categories; (a) Group C; no augmentation, (b) Group T1; bone defect filled with deproteinized bovine bone mineral (c) Group T2; bone defect filled with a biphasic bone graft material, (d) Group T3; bone defect filled as T1 and covered with a collagen membrane. Clinical and radiological examinations were performed, and biopsies were obtained and prepared for histological analysis 6 months after peri-implantitis surgery. Results Implant B (smooth surface) sites showed significantly (a) larger radiographic bone level gain, (b) enhanced resolution of peri-implantitis lesions, and (c) larger frequency of re-osseointegration than implant A (moderately rough surface) sites. Implant B sites also showed superior preservation of the mucosal margin. Differences between bone substitute materials and control procedures were overall small with limited advantages for T1 and T2 sites. Conclusion Healing following reconstructive surgical treatment of experimental peri-implantitis was superior around implants with a smooth surface than implants with a moderately rough surface. Benefits of using bone substitute materials during surgical therapy were overall small.
|
|
| 32. |
- Almohandes, Ahmed, et al.
(författare)
-
Surgical treatment of experimental peri-implantitis using mechanical and chemical decontamination procedures: A pre-clinical in vivo study
- 2022
-
Ingår i: Journal of Clinical Periodontology. - : Wiley. - 0303-6979 .- 1600-051X. ; 49:5, s. 518-525
-
Tidskriftsartikel (refereegranskat)abstract
- Aim: To evaluate the effect of surgical treatment of experimental peri-implantitis at implants with different surface characteristics using mechanical and chemical decontamination methods. Materials and Methods: Following extraction of mandibular premolars, four implants with two different surface characteristics (A, moderately rough and B, smooth) were placed in each side of the mandible of six dogs. Experimental peri-implantitis was induced. Surgical treatment of the peri-implantitis sites was carried out using four implant surface decontamination protocols: (i) deposition of a citric acid gel, (ii) mechanical cleaning using a rotating titanium brush, (iii) a combination of the mechanical and chemical procedures, and (iv) saline (control). Clinical and radiographic examinations were performed. Block biopsies were obtained 6months after therapy and prepared for histological analysis. Results: Irrespective of the treatment group, treatment resulted in 0.63 ± 0.92 and 0.65 ± 0.67 mm radiographic bone gain around implants A and B, respectively. Histological analyses revealed that persisting soft tissue inflammation as assessed using an infiltrated connective tissue (ICT) score was significantly lower at implant type B than at implant type A for all treatment groups. The test decontamination procedures did not demonstrate better results regarding resolution of peri-implantitis lesions, as indicated by the ICT scores, than the control procedure. The control treatment resulted in significantly superior outcomes of resolution of peri-implantitis lesions than the citric acid regimen. Conclusions: It is concluded that decontamination procedures including citric acid gel or rotating titanium brush did not improve outcomes following surgical treatment of experimental peri-implantitis. Results were, however, influenced by the implant surface characteristics. © 2022 John Wiley & Sons A/S.
|
|
| 33. |
- Berglundh, Tord, 1954, et al.
(författare)
-
Bone healing at implants with a fluoride-modified surface: an experimental study in dogs.
- 2007
-
Ingår i: Clinical oral implants research. - : Wiley. - 0905-7161 .- 1600-0501. ; 18:2, s. 147-52
-
Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: The aim of the present experiment was to study early stages of osseointegration to implants with a fluoride-modified surface. MATERIAL AND METHODS: Six mongrel dogs, about 1-year old, were used. All mandibular premolars and the first mandibular molars were extracted. Three months later, mucoperiosteal flaps were elevated in one side of the mandible and six sites were identified for implant placement. The control implants (MicroThread) had a TiOblast surface, while the test implants (OsseoSpeed) had a fluoride-modified TiOblast surface. Both types of implants had a similar geometry, a diameter of 3.5 mm and were 8 mm long. Following installation, cover screws were placed and the flaps were adjusted and sutured to cover all implants. Four weeks after the first implant surgery, the installation procedure was repeated in the opposite side of the mandible. Two weeks later, biopsies were obtained and prepared for histological analysis. The void that occurred between the cut bone wall of the recipient site and the macro-threads of the implant immediately following implant installation was used to study early bone formation. RESULTS: It was demonstrated that the amount of new bone that formed in the voids within the first 2 weeks of healing was larger at fluoride-modified implants (test) than at TiOblast (control) implants. It was further observed that the amount of bone-to-implant contact that had been established after 2 weeks in the macro-threaded portion of the implant was significantly larger at the test implants than at the controls. CONCLUSION: It is suggested that the fluoride-modified implant surface promotes osseointegration in the early phase of healing following implant installation.
|
|
| 34. |
- Berglundh, Tord, 1954, et al.
(författare)
-
Bone reactions to longstanding functional load at implants: an experimental study in dogs.
- 2005
-
Ingår i: Journal of clinical periodontology. - 0303-6979. ; 32:9, s. 925-32
-
Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: The aims of the present investigation were (i) to study marginal bone level alterations following implant installation, abutment connection and functional loading and (ii) to analyse bone tissue reactions to functional load. MATERIAL AND METHODS: Six beagle dogs, about 1-year old, were used. All mandibular pre-molars were extracted. Three months later four implants of the Astra Tech Implants Dental System were installed in one side of the mandible and four standard fixtures of the Brånemark System were placed in the contralateral side of the mandible. Abutment connection was performed 3 months later and a plaque control programme was initiated. Three months after abutment connection fixed partial dentures (FPDs) made in gold were cemented to the maxillary canines and pre-molars. FPDs were also connected to the three posterior implants in each side of the mandible, while the mesial implant in each side was used as an unloaded control. Radiographs were obtained from all implant sites following implant installation, abutment connection and FPD placement. Ten months after the FPD placement the radiographic examination was repeated. The animals were sacrificed and biopsies from all implant sites were obtained and prepared for histological analysis. RESULTS: The radiographic analysis revealed that largest amount of bone loss occurred following implant installation and abutment connection and that this loss was more pronounced at Brånemark than at Astra implants. The bone level alterations that were observed at implants exposed to 10 months of functional load in both implant systems were small and did not differ from control sites. The histological analysis revealed that implants exposed to functional load exhibited a higher degree of bone-to-implant contact than control implants in both implant systems. CONCLUSION: It is suggested that functional load at implants may enhance osseointegration and does not result in marginal bone loss.
|
|
| 35. |
|
|
| 36. |
- Berglundh, Tord, 1954, et al.
(författare)
-
Morphogenesis of the peri-implant mucosa: an experimental study in dogs.
- 2007
-
Ingår i: Clinical oral implants research. - : Wiley. - 0905-7161 .- 1600-0501. ; 18:1, s. 1-8
-
Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: The objective of the present experiment was to study the morphogenesis of the mucosal attachment to implants made of c.p. titanium. MATERIAL AND METHODS: All mandibular premolars were extracted in 20 Labrador dogs. After a healing period of 3 months, four implants (ITI Dental Implant System) were placed in the right and left sides of the mandible. A non-submerged implant installation technique was used and the mucosal tissues were secured to the conical marginal portion of the implants with interrupted sutures. The sutures were removed after 2 weeks and a plaque control program including daily cleaning of the remaining teeth and the implants was initiated. The animals were sacrificed and biopsies were obtained at various intervals to provide healing periods extending from Day 0 (2 h) to 12 weeks. The mandibles were removed and placed in the fixative. The implant sites were dissected using a diamond saw and processed for histological analysis. RESULTS: Large numbers of neutrophils infiltrated and degraded the coagulum that occupied the compartment between the mucosa and the implant during the initial phase of healing. At 2 weeks after surgery, fibroblasts were the dominating cell population in the connective tissue interface but at 4 weeks the density of fibroblasts had decreased. Furthermore, the first signs of epithelial proliferation were observed in specimens representing 1-2 weeks of healing and a mature barrier epithelium occurred after 6-8 weeks of healing. The collagen fibers of the mucosa were organized after 4-6 weeks of healing. CONCLUSION: It is suggested that the soft-tissue attachment to implants placed using a non-submerged installation procedure is properly established after several weeks following surgery.
|
|
| 37. |
- Carcuac, Olivier, 1974, et al.
(författare)
-
Adjunctive Systemic and Local Antimicrobial Therapy in the Surgical Treatment of Peri-implantitis: A Randomized Controlled Clinical Trial
- 2016
-
Ingår i: Journal of Dental Research. - : SAGE Publications. - 0022-0345 .- 1544-0591. ; 95:1, s. 50-57
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of the present randomized controlled clinical trial was to investigate the adjunctive effect of systemic antibiotics and the local use of chlorhexidine for implant surface decontamination in the surgical treatment of peri-implantitis. One hundred patients with severe peri-implantitis were recruited. Surgical therapy was performed with or without adjunctive systemic antibiotics or the local use of chlorhexidine for implant surface decontamination. Treatment outcomes were evaluated at 1 y. A binary logistic regression analysis was used to identify factors influencing the probability of treatment success, that is, probing pocket depth <= 5 mm, absence of bleeding/suppuration on probing, and no additional bone loss. Treatment success was obtained in 45% of all implants but was higher in implants with a nonmodified surface (79%) than those with a modified surface (34%). The local use of chlorhexidine had no overall effect on treatment outcomes. While adjunctive systemic antibiotics had no impact on treatment success at implants with a nonmodified surface, a positive effect on treatment success was observed at implants with a modified surface. The likelihood for treatment success using adjunctive systemic antibiotics in patients with implants with a modified surface, however, was low. As the effect of adjunctive systemic antibiotics depended on implant surface characteristics, recommendations for their use in the surgical treatment of peri-implantitis should be based on careful assessments of the targeted implant (ClinicalTrials.gov NCT01857804).
|
|
| 38. |
- Carcuac, Olivier, 1974, et al.
(författare)
-
Experimental periodontitis and peri-implantitis in dogs
- 2013
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161. ; 24:4, s. 363-371
-
Tidskriftsartikel (refereegranskat)abstract
- Abstract Aim: To analyze the tissue reactions following ligature removal in experimental periodontitis and peri-implantitis in dogs. Material and methods: Four implants with similar geometry and with two different surface characteristics (turned/TiUnite Nobel BioCare AB, Go ̈ teborg) were placed pair-wise in a randomized order in the right side of the mandible 3 months after tooth extraction in 5 dogs. Experimental peri-implantitis and periodontitis were initiated 3 months later by ligature placement around implants and mandibular premolars and plaque formation. The ligatures were removed after 10 weeks, and block biopsies were obtained and prepared for histological analysis 6 months later. Results: It was demonstrated that the amount of bone loss that occurred during the period following ligature removal was significantly larger at implants with a modified surface than at implants with a turned surface and at teeth. The histological analysis revealed that peri-implantitis sites exhibited inflammatory cell infiltrates that were larger, extended closer to the bone crest and contained larger proportions of neutrophil granulocytes and osteoclasts than in periodontitis. Conclusion: It is suggested that lesions produced in experimental periodontitis, and peri- implantitis are different and that implant surface characteristics influence the inflammatory process in experimental peri-implantitis and the magnitude of the resulting tissue destruction.
|
|
| 39. |
- Carcuac, Olivier, 1974, et al.
(författare)
-
Risk for recurrence of disease following surgical therapy of peri-implantitis-A prospective longitudinal study
- 2020
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 31:11, s. 1072-1077
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives The aim of the present prospective study was to assess the risk for disease recurrence following surgical therapy of peri-implantitis. Material & Methods 73 patients (130 implants) treated surgically for peri-implantitis were examined at 1 and 5 years after therapy. The primary outcome was recurrence/progression of disease defined as any of the following events: (a) bone loss >1.0 mm, (b) surgical retreatment, (c) implant removal/loss after year 1. Patient- and implant-related parameters as well as 1-year outcomes were evaluated as potential predictors through multiple logistic regression analysis. Results 57 implants (44%) displayed recurrence/progression of peri-implantitis during follow-up. Among these, 27 implants were removed. Residual deep probing pocket depth (>= 6 mm; odds ratio 7.4; 95% confidence interval 2.8-19.3) and reduced marginal bone level (OR 1.4; 95%CI 1.1-1.7) at 1 year after surgery constituted risk factors for recurrence/progression of disease. Furthermore, implants with modified surfaces were at higher risk than implants with non-modified surfaces (OR 5.1; 95%CI 1.6-16.5). Conclusion Implants with (a) residual deep probing pocket depth, (b) reduced marginal bone level, or (c) modified surfaces following surgical therapy of peri-implantitis present with increased risk for recurrence/progression.
|
|
| 40. |
- Carcuac, Olivier, 1974, et al.
(författare)
-
Spontaneous progression of experimental peri-implantitis in augmented and pristine bone. A pre-clinical in vivo study.
- 2020
-
Ingår i: Clinical oral implants research. - : Wiley. - 1600-0501 .- 0905-7161. ; 31:2, s. 192-200
-
Tidskriftsartikel (refereegranskat)abstract
- To examine progression of experimental peri-implantitis around different implants placed in augmented and pristine sites. M&M: 6 Labrador dogs were used. 3months after tooth extraction, 4 implants with different surface modifications were installed on each side of the mandible. A standard osteotomy was applied on one side, while on the contralateral side the osteotomy was modified, resulting in a gap between the implant and the bone wall. The gap was filled with a bone substitute and covered by a resorbable membrane. 3months after implant installation, implants were exposed and healing abutments were connected. 2months later, oral hygiene procedures were abandoned and a cotton ligature was placed in a submarginal position around the neck of all implants and kept in place for 4weeks. Following ligature removal, plaque formation continued for 6months (spontaneous progression period). Radiographs were obtained throughout the experiment and biopsies were collected and prepared for histological evaluation at the end of the spontaneous progression period.Differences in bone loss during the spontaneous progression period between pristine and augmented sites were small. The size and vertical dimension of the peri-implantitis lesion were larger at augmented than at pristine sites. Implants with non-modified surfaces exhibited smaller amounts of bone loss and smaller dimensions of peri-implantitis lesions than implants with modified surfaces.Small differences in spontaneous progression of peri-implantitis were detected between pristine and augmented sites. Implants with modified surfaces exhibited more bone loss and larger lesions than implants with non-modified surfaces, irrespective of the type of surrounding bone.
|
|
| 41. |
- Carcuac, Olivier, 1974, et al.
(författare)
-
Surgical treatment of peri-implantitis: 3-year results from a randomized controlled clinical trial.
- 2017
-
Ingår i: Journal of clinical periodontology. - : Wiley. - 1600-051X .- 0303-6979. ; 44:12, s. 1294-1303
-
Tidskriftsartikel (refereegranskat)abstract
- This study reports on the 3-year follow-up of patients enrolled in a randomized controlled clinical trial on surgical treatment of advanced peri-implantitis.A total of 100 patients with advanced peri-implantitis were randomly assigned to one of four treatment groups. Surgical therapy aiming at pocket elimination was performed and, in three test groups, supplemented by either systemic antibiotics, use of an antiseptic agent for implant surface decontamination or both. Outcomes were evaluated after 1 and 3years by means of clinical and radiological examinations. Differences between groups were explored by regression analysis.Clinical examinations at 3years after treatment revealed (i) improved peri-implant soft tissue health with a mean reduction in probing depth of 2.7mm and a reduction in bleeding/suppuration on probing of 40% and (ii) stable peri-implant marginal bone levels (mean bone loss during follow-up: 0.04mm). Implant surface characteristics had a significant impact on 3-year outcomes, in favour of implants with non-modified surfaces. Benefits of systemic antibiotics were limited to implants with modified surfaces and to the first year of follow-up.It is suggested that surgical treatment of peri-implantitis is effective and that outcomes of therapy are affected by implant surface characteristics. Potential benefits of systemic antibiotics are not sustained over 3years.
|
|
| 42. |
- Carcuac, Olivier, 1974, et al.
(författare)
-
The effect of the local use of chlorhexidine in surgical treatment of experimental peri-implantitis in dogs
- 2015
-
Ingår i: Journal of Clinical Periodontology. - : Wiley. - 0303-6979. ; 42:2, s. 196-203
-
Tidskriftsartikel (refereegranskat)abstract
- Aim: To evaluate the effect of surgical treatment of experimental peri-implantitis at implants with different surface characteristics using different anti-infective procedures. Material and methods: Four implants with different surface characteristics (A: TiOblast, B: OsseoSpeed, C: AT-I, D: TiUnite) were installed in a random- ized order in each side of the mandible in 6 labrador dogs 3 months after tooth extraction. Experimental peri-implantitis was induced 3 months later. Surgical treatment of peri-implantitis was performed. The implants were cleaned with gauze soaked in either saline (control) or chlorhexidine (test). Clinical and radio- graphical examinations were performed and microbiological samples were taken during a 6-month period after surgery. Biopsies were obtained and prepared for histological analysis. Results: Clinical signs of soft tissue inflammation were reduced after surgical therapy in most test and control sites. While the analysis of bone level alterations in radiographs together with histological and microbiological assessments of reso- lution of peri-implantitis lesions failed to demonstrate statistically significant dif- ferences between test and control procedures, the evaluations disclosed significant differences between implant D and implants A, B and C on treatment outcome. Conclusion: It is suggested that (i) the local use of chlorhexidine has minor influ- ence on treatment outcome, (ii) resolution of peri-implantitis following surgical treatment without the adjunctive use of local and systemic antimicrobial agents is possible and (iii) the results are influenced by implant surface characteristics.
|
|
| 43. |
- Charalampakis, Georgios, et al.
(författare)
-
Effect of cleansing of biofilm formed on titanium discs.
- 2015
-
Ingår i: Clinical oral implants research. - : Wiley. - 1600-0501 .- 0905-7161. ; 26:8, s. 931-936
-
Tidskriftsartikel (refereegranskat)abstract
- To study the combined effect of mechanical and chemical cleansing on a 4-day biofilm grown intra-orally on titanium discs with different surface characteristics.
|
|
| 44. |
- Charalampakis, Georgios, et al.
(författare)
-
Microbiota in experimental periodontitis and peri-implantitis in dogs
- 2014
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161. ; 25:9, s. 1094-1098
-
Tidskriftsartikel (refereegranskat)abstract
- Aim To analyze the microbial profile around teeth and implants following ligature removal in experimental periodontitis and peri-implantitis in dogs. Material and methods Four implants with similar geometry and with two different surface characteristics (implant A: turned/implant B: TiUnite; NobelBiocare AB) were placed pairwise in the right side of the mandible 3 months after tooth extraction in five dogs. Experimental periodontitis and peri-implantitis were initiated 3 months later by ligature placement around implants and mandibular premolars and plaque formation. The ligatures were removed after 10 weeks. Microbial samples were obtained using paper points immediately after ligature removal, at 10 and 25 weeks after ligature removal. The microbiological analysis was performed by “checkerboard” DNA-DNA hybridization, including a panel of 16 bacterial species. Results The amount of bone loss that occurred during the period following ligature removal was significantly larger at implants with a modified surface than at implants with a turned surface and at teeth. The microbiological analysis revealed that the total bacterial load increased during the period following ligature removal and established an anaerobic Gram-negative microflora. Conclusion It is suggested that the large variation in regard to the microbial profiles makes interpretation of a correlation between disease progression and microbial profiles difficult.
|
|
| 45. |
- Dahlén, Gunnar, 1944, et al.
(författare)
-
Predominant bacterial species in subgingival plaque in dogs.
- 2012
-
Ingår i: Journal of periodontal research. - : Wiley. - 1600-0765 .- 0022-3484. ; 47:3, s. 354-364
-
Tidskriftsartikel (refereegranskat)abstract
- Dahlén G, Charalampakis G, Abrahamsson I, Bengtsson L, Falsen E. Predominant bacterial species in subgingival plaque in dogs. J Periodont Res 2011; doi: 10.1111/j.1600-0765.2011.01440.x.©2011 John Wiley & Sons A/S Background and Objective: The dog has been used extensively for experimental and microbiological studies on periodontitis and peri-implantitis without detailed knowledge about the predominant flora of the subgingival plaque. This study was designed to evaluate the predominant cultivable bacterial species in dogs and compare them phenotypically and genotypically with corresponding human species. Material and Methods: Four subgingival samples were taken from two upper premolars in each of six Labrador retrievers. The samples from each dog were processed for anaerobic culture. From the samples of each dog, the five or six predominating bacteria based on colony morphology were selected and pure cultured. Each of the strains was characterized by Gram stain, anaerobic/aerobic growth and API-ZYM test. Eighteen strains showing clear-cut phenotypic differences were further classified based on DNA sequencing technology. Cross-reactions of DNA probes from human and dog strains were also tested against a panel of both human and dog bacterial species. Results: Thirty-one strains in the dogs were isolated and characterized. They represented 21 different species, of which six belonged to the genus Porphyromonas. No species was found consistently in the predominant flora of all six dogs. Porphyromonas crevioricanis and Fusobacterium canifelinum were the two most prevalent species in predominant flora in dogs. DNA probes from human and dog species cross-reacted to some extent with related strains from humans and dogs; however, distinct exceptions were found. Conclusion: The predominant cultural subgingival flora in dogs shows great similarities with the subgingival bacteria from humans at the genus level, but distinct differences at the species level; however, a genetic relatedness could be disclosed for most strains investigated.
|
|
| 46. |
- Derks, Jan, 1977, et al.
(författare)
-
Reconstructive surgical therapy of peri-implantitis: A multicenter randomized controlled clinical trial
- 2022
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 33:9, s. 921-944
-
Tidskriftsartikel (refereegranskat)abstract
- Objective To evaluate the potential benefit of the use of a bone substitute material in the reconstructive surgical therapy of peri-implantitis. Methods In this multicenter randomized clinical trial, 138 patients (147 implants) with peri-implantitis were treated surgically, randomized by coin toss to either a control (access flap surgery) or a test group (reconstructive surgery using bone substitute material). Clinical assessments, including probing pocket depth (PPD), bleeding and suppuration on probing (BOP & SOP) as well as soft tissue recession (REC), were recorded at baseline, 6 and 12 months. Marginal bone levels (MBL), measured on intra-oral radiographs, and patient-reported outcomes (PROs) were recorded at baseline and 12 months. No blinding to group allocation was performed. The primary outcome at 12 months was a composite measure including (i) implant not lost, (ii) absence of BOP/SOP at all aspects, (iii) PPD <= 5 mm at all aspects and (iv) <= 1 mm recession of mucosal margin on the buccal aspect of the implant. Secondary outcomes included (i) changes of MBL, (ii) changes of PPD, BOP%, and buccal KM, (iii) buccal REC and (iv) patient-reported outcomes. Results During follow-up, four implants (one in the test group, three in the control group) in four patients were removed due to disease progression. At 12 months, a total of 69 implants in the test and 68 implants in the control group were examined. Thus, 16.4% and 13.5% of implants in the test and control group, respectively, met all predefined criteria of the composite outcome. PPD reduction and MBL gain were 3.7 mm and about 1.0 mm in both groups. Reduction in mean BOP% varied between 45% (test) and 50% (control), without significant differences between groups. Buccal REC was less pronounced in the test group (M = 0.7, SD = 0.9 mm) when compared to controls (M = 1.1, SD = 1.5 mm). PROs were favorable in both groups without significant differences. One case of allergic reaction to the antibiotic therapy was recorded. No other adverse events were noted. Conclusions Surgical therapy of peri-implantitis effectively improved the clinical and radiographic status at 12 months. While the use of a bone substitute material did not improve reductions of PPD and BOP, buccal REC was less pronounced in the test group. Patient satisfaction was high in both groups.
|
|
| 47. |
- Guljé, Felix, et al.
(författare)
-
Implants of 6mm vs. 11mm lengths in the posterior maxilla and mandible: a 1-year multicenter randomized controlled trial.
- 2013
-
Ingår i: Clinical oral implants research. - : Wiley. - 1600-0501 .- 0905-7161. ; 24:12, s. 1325-1331
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND AND AIM: In cases with limited bone height, short implants could be a good alternative to augmentation procedures. The aim of this randomized controlled trial was to compare the clinical performance of implants of 6mm or 11mm in length in the posterior region. MATERIALS AND METHODS: In this multicenter trial (six study sites), 95 subjects were included. Subjects were randomly allocated to receiving implants with lengths of either 6 or 11mm both with a diameter of 4mm (OsseoSpeed(™) 4.0 S; Astra Tech AB; Mölndal, Sweden). In all cases, there had to be sufficient bone height to allow placement of an implant of at least 11mm in length. Two or three implants were placed per subject using one-stage surgery with a 42-48days' healing period before loading. They were restored with a screw-retained splinted fixed prosthesis. Clinical and radiographic examinations were performed preoperatively, postsurgery, at loading, and 6 and 12months after prosthesis placement. RESULTS: A total of 208 implants were inserted in 49 subjects receiving 6-mm implants (test) and in 46 subjects receiving 11mm implants (control). Two 6-mm implants failed before loading and one 6 and 11mm implants failed before 1-year evaluation. From loading to the 12months' follow-up, a mean marginal bone gain of 0.06mm in the 6mm group and 0.02mm in the 11mm group was found (P=0.478). Soft tissue behavior was equal in both groups (Bleeding and plaque [P=1.0] probing depth [P=0.91]). CONCLUSION: One-year data indicate that treatment with the 6mm implants is as reliable as treatment with the 11mm implants. This provides a good treatment option in situations with limited bone height in the premolar and molar regions. Whether or not short implants provide a predictable treatment alternative to bone augmentation procedures remains to be investigated in the future randomized controlled clinical trials.
|
|
| 48. |
- Gulje, F. L., et al.
(författare)
-
Comparison of 6-mm and 11-mm dental implants in the posterior region supporting fixed dental prostheses: 5-year results of an open multicenter randomized controlled trial
- 2021
-
Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 32:1, s. 15-22
-
Tidskriftsartikel (refereegranskat)abstract
- Objective The aim of this multicenter, randomized controlled trial was to compare the clinical and radiographic outcomes of 6-mm or 11-mm implants, placed in the posterior maxilla and mandible, during a 5-year follow-up period. Materials and methods Ninety-five patients with adequate bone height for 11-mm implants, were randomly allocated to a 6-mm group (test group with short implants) or an 11-mm group (control group with standard-length implants). Two or three implants of the same length were placed in each patient and after 6 weeks loaded with a splinted provisional restoration. This was followed by definitive splinted restoration 6 months after implant placement. Clinical and radiographic parameters, including the occurrence of complications were recorded. Results A total of 49 patients were enrolled to receive 6-mm implants (n = 108) and 46 patients to receive 11-mm implants (n = 101). Three implants (two of 6 mm and one of 11 mm in length) were lost before loading and one 6-mm implant after 15 months of function, and one 11-mm implant was lost during the first year of function. The 5-year survival rates were 96.0% and 98.9% in the 6-mm and 11-mm group, respectively. The mean marginal bone level changes 5 years post-loading were 0.01 +/- 0.45 mm (bone gain) in the 6-mm group and -0.12 +/- 0.93 mm (bone loss) in the 11-mm group (p = .7670). Clinical parameters, including plaque, bleeding on probing and pocket probing depth were not significantly different between the groups, and also technical complications were low. Conclusion The clinical and radiographic outcomes of 6-mm short and 11-mm standard-length implants were not different during a 5-year evaluation period.
|
|
| 49. |
- Ichioka, Yuki, et al.
(författare)
-
Factors influencing outcomes of surgical therapy of peri-implantitis: A secondary analysis of 1-year results from a randomized clinical study
- 2023
-
Ingår i: JOURNAL OF CLINICAL PERIODONTOLOGY. - 0303-6979. ; 50:10, s. 1282-1304
-
Tidskriftsartikel (refereegranskat)abstract
- Aim: To identify predictors of treatment outcomes following surgical therapy of peri-implantitis.Materials and Methods: We performed a secondary analysis of data from a randomized controlled trial (RCT) comparing access flap with or without bone replacement graft. Outcomes at 12 months were probing pocket depth (PPD), bleeding on probing (BOP), soft-tissue recession (REC) and marginal bone level (MBL) change. Multilevel regression analyses were used to identify predictors. We also built an explanatory model for residual signs of inflammation.Results: Baseline PPD was the most relevant predictor, showing positive associations with final PPD, REC and MBL gain, and negative association with probability of pocket closure. Smokers presented higher residual PPD. Absence of keratinized mucosa at baseline increased the probability of BOP but was otherwise not indicative of outcomes. Plaque at 6 weeks was detrimental in terms of residual PPD and BOP. Treatment allocation had an effect on REC. Final BOP was explained by residual PPD & GE;6 mm and plaque at more than two sites.Conclusions: Baseline PPD was the most relevant predictor of the outcomes of surgical therapy of peri-implantitis. Pocket closure should be a primary goal of treatment. Bone replacement grafts may be indicated in aesthetically demanding cases to reduce soft-tissue recession. The importance of smoking cessation and patient-performed plaque control is also underlined.
|
|
| 50. |
- Kato, Takahiro, 1983, et al.
(författare)
-
Periodontal disease among older people and its impact on oral health-related quality of life.
- 2018
-
Ingår i: Gerodontology. - : Wiley. - 1741-2358 .- 0734-0664. ; 35:4, s. 382-390
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of the study was to evaluate the associations between degree of periodontal disease and number of teeth on oral health-related quality of life among older individuals.Randomly selected 804 participants aged ≥70 derived from two cohorts were included in the analysis. Dental examinations and evaluation of OHRQL using the OHIP-14 (Oral Health Impact Profile-14) were performed. After categorisation of the participants according to the extent of periodontitis in three groups (none, localised with <30% of teeth affected, generalised with ≥30% of teeth affected) and the number of teeth, associations between periodontal status and the number of teeth and the OHIP-14 scores were analysed. Multivariable regression analyses were used taking into account level of periodontitis, number of teeth, age and sex.Among 70-year-old men and women, generalised periodontitis showed an association with poor OHRQL. However, a multivariable analysis failed to demonstrate this association (OR=1.02, 95% CI: 0.72-1.44). In participants with 1-10 remaining teeth, the OHIP-14 score was significantly increased indicating poor OHRQL, compared with participants with ≥21 remaining teeth (OR=1.57, 95% CI: 1.13-2.19). Similar findings were observed among women aged 70-92years.Periodontitis did not show an association with poor OHRQL, however, a significant association between the number of teeth and poor OHRQL was found.
|
|
